Gallagher EJ, Leroith D, Karnieli E: Insulin resistance in obesity as the underlying cause for the metabolic syndrome. Mt Sinai J Med. 2010, 77: 511-523. 10.1002/msj.20212.
Article
PubMed
Google Scholar
DeFronzo RA, Ferrannini E: Insulin resistance: a multifaceted syndrome responsible for NIDDM, obesity, hypertension, dyslipidemia, and atherosclerotic cardiovascular disease. Diabetes Care. 1991, 14: 173-194. 10.2337/diacare.14.3.173.
Article
CAS
PubMed
Google Scholar
Fontbonne AM, Eschwege EM: Insulin and cardiovascular disease: Paris prospective study. Diabetes Care. 1991, 14: 461-469. 10.2337/diacare.14.6.461.
Article
CAS
PubMed
Google Scholar
Eckel RH, Grundy SM, Zimmet PZ: The metabolic syndrome. Lancet. 2005, 365: 1415-1428. 10.1016/S0140-6736(05)66378-7.
Article
CAS
PubMed
Google Scholar
Matthews DR, Hosker JP, Rudenski AS, Naylor BA, Treacher DF, Turner RC: Homeostasis model assessment: insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man. Diabetologia. 1985, 28: 412-419. 10.1007/BF00280883.
Article
CAS
PubMed
Google Scholar
Meisinger C, Löwel H, Heier M, Schneider A, Thorand B, KORA Study Group: Serum gamma-glutamyltransferase and risk of type 2 diabetes mellitus in men and women from the general population. J Intern Med. 2005, 258: 527-535. 10.1111/j.1365-2796.2005.01572.x.
Article
CAS
PubMed
Google Scholar
Wannamethee SG, Shaper AG, Lennon L, Whincup PH: Hepatic enzymes, the metabolic syndrome, and the risk of type 2 diabetes in older men. Diabetes Care. 2005, 28: 2913-2918. 10.2337/diacare.28.12.2913.
Article
CAS
PubMed
Google Scholar
Doi Y, Kubo M, Yonemoto K, Ninomiya T, Iwase M, Tanizaki Y, Shikata K, Iida M, Kiyohara Y: Liver enzymes as a predictor for incident diabetes in a Japanese population: the Hisayama study. Obesity (Silver Spring). 2007, 15: 1841-1850. 10.1038/oby.2007.218.
Article
CAS
Google Scholar
Monami M, Bardini G, Lamanna C, Pala L, Cresci B, Francesconi P, Buiatti E, Rotella CM, Mannucci E: Liver enzymes and risk of diabetes and cardiovascular disease: results of the Firenze Bagno a Ripoli (FIBAR) study. Metabolism. 2008, 57: 387-392. 10.1016/j.metabol.2007.10.015.
Article
CAS
PubMed
Google Scholar
Gao F, Pan JM, Hou XH, Fang QC, Lu HJ, Tang JL, Gu HL, Pan ZJ, Yao YH, Shen WZ, Jia WP: Liver enzyme concentrations are closely related to prediabetes: findings of the Shanghai Diabetes Study II (SHDS II). Biomed Environ Sci. 2012, 25: 30-37.
CAS
PubMed
Google Scholar
André P, Balkau B, Vol S, Charles MA, Eschwège E, DESIR Study Group: Gamma-glutamyltransferase activity and development of the metabolic syndrome (International Diabetes Federation Definition) in middle-aged men and women: Data from the Epidemiological Study on the Insulin Resistance Syndrome (DESIR) cohort. Diabetes Care. 2007, 30: 2355-2361. 10.2337/dc07-0440.
Article
PubMed
Google Scholar
Xu Y, Bi YF, Xu M, Huang Y, Lu WY, Gu YF, Ning G, Li XY: Cross-sectional and longitudinal association of serum alanine aminotransaminase and γ-glutamyltransferase with metabolic syndrome in middle-aged and elderly Chinese people. J Diabetes. 2011, 3: 38-47. 10.1111/j.1753-0407.2010.00111.x.
Article
CAS
PubMed
Google Scholar
Steinvil A, Shapira I, Ben-Bassat OK, Cohen M, Vered Y, Berliner S, Rogowski O: The association of higher levels of within-normal-limits liver enzymes and the prevalence of the metabolic syndrome. Cardiovasc Diabetol. 2010, 9: 30-10.1186/1475-2840-9-30.
Article
PubMed Central
PubMed
Google Scholar
Sookoian S, Pirola CJ: Alanine and aspartate aminotransferase and glutamine-cycling pathway: Their roles in pathogenesis of metabolic syndrome. World J Gastroenterol. 2012, 18: 3775-3781. 10.3748/wjg.v18.i29.3775.
Article
PubMed Central
CAS
PubMed
Google Scholar
Vozarova B, Stefan N, Lindsay RS, Saremi A, Pratley RE, Bogardus C, Tataranni PA: High alanine aminotransferase is associated with decreased hepatic insulin sensitivity and predicts the development of type 2 diabetes. Diabetes. 2002, 51: 1889-1895. 10.2337/diabetes.51.6.1889.
Article
CAS
PubMed
Google Scholar
Ortega E, Koska J, Salbe AD, Tataranni PA, Bunt JC: Serum gamma-glutamyl transpeptidase is a determinant of insulin resistance independently of adiposity in Pima Indian children. J Clin Endocrinol Metab. 2006, 91: 1419-1422. 10.1210/jc.2005-1783.
Article
CAS
PubMed
Google Scholar
Kawamoto R, Tabara Y, Kohara K, Miki T, Kusunoki T, Takayama S, Abe M, Katoh T, Ohtsuka N: High-sensitivity C-reactive protein and gamma-glutamyl transferase levels are synergistically associated with metabolic syndrome in community-dwelling persons. Cardiovasc Diabetol. 2010, 9: 87-10.1186/1475-2840-9-87.
Article
PubMed Central
CAS
PubMed
Google Scholar
Kawamoto R, Kohara K, Tabara Y, Miki T: An association between metabolic syndrome and the estimated glomerular filtration rate. Intern Med. 2008, 47: 1399-1406. 10.2169/internalmedicine.47.1202.
Article
PubMed
Google Scholar
Friedewald WT, Levy RI, Fredrickson DS: Estimation of the concentration of low-density lipoprotein cholesterol in plasma, without use of the preparative ultracentrifuge. Clin Chem. 1972, 18: 499-502.
CAS
PubMed
Google Scholar
Yeni-Komshian H, Carantoni M, Abbasi F, Reaven GM: Relationship between several surrogate estimates of insulin resistance and quantification of insulin-mediated glucose disposal in 490 healthy nondiabetic volunteers. Diabetes Care. 2000, 23: 171-175. 10.2337/diacare.23.2.171.
Article
CAS
PubMed
Google Scholar
Taniguchi A, Fukushima M, Sakai M, Kataoka K, Miwa K, Nagata I, Doi K, Tokuyama K, Nakai Y: Insulin-sensitive and insulin-resistant variants in nonobese Japanese type 2 diabetic patients. The role of triglycerides in insulin resistance. Diabetes Care. 1999, 22: 2100-2101. 10.2337/diacare.22.12.2100.
Article
CAS
PubMed
Google Scholar
Bonora E, Kiechl S, Willeit J, Oberhollenzer F, Egger G, Targher G, Alberiche M, Bonadonna RC, Muggeo M: Prevalence of insulin resistance in metabolic disorders: the Bruneck Study. Diabetes. 1998, 47: 1643-1649. 10.2337/diabetes.47.10.1643.
Article
CAS
PubMed
Google Scholar
Wallace TM, Levy JC, Matthews DR: Use and abuse of HOMA modeling. Diabetes Care. 2004, 27: 1487-1495. 10.2337/diacare.27.6.1487.
Article
PubMed
Google Scholar
Kim-Dorner SJ, Deuster PA, Zeno SA, Remaley AT, Poth M: Should triglycerides and the triglycerides to high-density lipoprotein cholesterol ratio be used as surrogates for insulin resistance?. Metabolism. 2010, 59: 299-304. 10.1016/j.metabol.2009.07.027.
Article
CAS
PubMed
Google Scholar
Kannel WB, Vasan RS, Keyes MJ, Sullivan LM, Robins SJ: Usefulness of the triglyceride-high-density lipoprotein versus the cholesterol-high-density lipoprotein ratio for predicting insulin resistance and cardiometabolic risk (from the Framingham Offspring Cohort). Am J Cardiol. 2008, 101: 497-501. 10.1016/j.amjcard.2007.09.109.
Article
PubMed Central
CAS
PubMed
Google Scholar
Tamada M, Makita S, Abiko A, Naganuma Y, Nagai M, Nakamura M: Low-density lipoprotein cholesterol to high-density lipoprotein cholesterol ratio as a useful marker for early-stage carotid atherosclerosis. Metabolism. 2010, 59: 653-657. 10.1016/j.metabol.2009.09.009.
Article
CAS
PubMed
Google Scholar
Kimm H, Lee SW, Lee HS, Shim KW, Cho CY, Yun JE, Jee SH: Associations between lipid measures and metabolic syndrome, insulin resistance and adiponectin. - Usefulness of lipid ratios in Korean men and women. Circ J. 2010, 74: 931-937. 10.1253/circj.CJ-09-0571.
Article
CAS
PubMed
Google Scholar
Kawamoto R, Tabara Y, Kohara K, Miki T, Kusunoki T, Takayama S, Abe M, Katoh T, Ohtsuka N: Relationships between lipid profiles and metabolic syndrome, insulin resistance and serum high molecular adiponectin in Japanese community-dwelling adults. Lipids Health Dis. 2011, 10: 79-10.1186/1476-511X-10-79.
Article
PubMed Central
CAS
PubMed
Google Scholar
Ioannou GN, Weiss NS, Boyko EJ, Kahn SE, Lee SP: Contribution of metabolic factors to alanine aminotransferase activity in persons with other causes of liver disease. Gastroenterology. 2005, 128: 627-635. 10.1053/j.gastro.2004.12.004.
Article
CAS
PubMed
Google Scholar
Hanley AJ, Wagenknecht LE, Festa A, D'Agostino RB, Haffner SM: Alanine aminotransferase and directly measured insulin sensitivity in a multiethnic cohort: the Insulin Resistance Atherosclerosis Study. Diabetes Care. 2007, 30: 1819-1827. 10.2337/dc07-0086.
Article
CAS
PubMed
Google Scholar
Homsanit M, Sanguankeo A, Upala S, Udol K: Abnormal liver enzymes in Thai patients with metabolic syndromes. J Med Assoc Thai. 2012, 95: 444-451.
PubMed
Google Scholar
Seppälä-Lindroos A, Vehkavaara S, Häkkinen AM, Goto T, Westerbacka J, Sovijärvi A, Halavaara J, Yki-Järvinen H: Fat accumulation in the liver is associated with defects in insulin suppression of glucose production and serum free fatty acids independent of obesity in normal men. J Clin Endocrinol Metab. 2002, 87: 3023-3028. 10.1210/jc.87.7.3023.
Article
PubMed
Google Scholar
Browning JD, Szczepaniak LS, Dobbins R, Nuremberg P, Horton JD, Cohen JC, Grundy SM, Hobbs HH: Prevalence of hepatic steatosis in an urban population in the United States: impact of ethnicity. Hepatology. 2004, 40: 1387-1395. 10.1002/hep.20466.
Article
PubMed
Google Scholar
Nanji AA, French SW, Freeman JB: Serum alanine aminotransferase to aspartate aminotransferase ratio and degree of fatty liver in morbidly obese patients. Enzyme. 1986, 36: 266-269.
CAS
PubMed
Google Scholar
Marchesini G, Brizi M, Bianchi G, Tomassetti S, Bugianesi E, Lenzi M, McCullough AJ, Natale S, Forlani G, Melchionda N: Nonalcoholic fatty liver disease: a feature of the metabolic syndrome. Diabetes. 2001, 50: 1844-1850. 10.2337/diabetes.50.8.1844.
Article
CAS
PubMed
Google Scholar
Mulhall BP, Ong JP, Younossi ZM: Non-alcoholic fatty liver disease: an overview. J Gastroenterol Hepatol. 2002, 17: 1136-1143. 10.1046/j.1440-1746.2002.02881.x.
Article
CAS
PubMed
Google Scholar
Schindhelm RK, Diamant M, Dekker JM, Tushuizen ME, Teerlink T, Heine RJ: Alanine aminotransferase as a marker of non-alcoholic fatty liver disease in relation to type 2 diabetes mellitus and cardiovascular disease. Diabetes Metab Res Rev. 2006, 22: 437-443. 10.1002/dmrr.666.
Article
CAS
PubMed
Google Scholar