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  1. Content type: Original investigation

    Subtle impairments in left ventricular (LV) function and geometry are common findings in individuals with diabetes. However, whether these impairments precede the development of diabetes mellitus (DM) is not e...

    Authors: Daniel Modin, Rasmus Møgelvang, Peter Godsk Jørgensen, Magnus Thorsten Jensen, Jelena P. Seferovic and Tor Biering-Sørensen

    Citation: Cardiovascular Diabetology 2019 18:37

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  2. Content type: Original investigation

    Because weight control is a cornerstone of diabetes management, it is important to understand the relationship of weight change to risk of cardiovascular disease (CVD) among patients with type 2 diabetes melli...

    Authors: Mee Kyoung Kim, Kyungdo Han, Eun Sil Koh, Eun Sook Kim, Min-Kyung Lee, Ga Eun Nam and Hyuk-Sang Kwon

    Citation: Cardiovascular Diabetology 2019 18:36

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  3. Content type: Original investigation

    This pathophysiological study addressed the hypothesis that soluble epoxide hydrolase (sEH), which metabolizes the vasodilator and anti-inflammatory epoxyeicosatrienoic acids (EETs) to dihydroxyeicosatrienoic ...

    Authors: Thomas Duflot, Lucile Moreau-Grangé, Clothilde Roche, Michèle Iacob, Julien Wils, Isabelle Rémy-Jouet, Anne-Françoise Cailleux, Matthieu Leuillier, Sylvanie Renet, Dongyang Li, Christophe Morisseau, Fabien Lamoureux, Vincent Richard, Gaëtan Prévost, Robinson Joannidès and Jérémy Bellien

    Citation: Cardiovascular Diabetology 2019 18:35

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  4. Content type: Original investigation

    Exercise, when performed on a regular basis, is a well-accepted strategy to improve vascular function in patients with type 2 diabetes. However, the exercise intensity that yields maximal adaptations on struct...

    Authors: João P. Magalhães, Xavier Melo, Inês R. Correia, Rogério T. Ribeiro, João Raposo, Hélder Dores, Manuel Bicho and Luís B. Sardinha

    Citation: Cardiovascular Diabetology 2019 18:34

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  5. Content type: Original investigation

    To evaluate the characteristics of type 2 diabetes (T2DM) patients with or without chronic kidney disease (CKD) in Germany.

    Authors: Peter Bramlage, Stefanie Lanzinger, Gesine van Mark, Eva Hess, Simon Fahrner, Christoph H. J. Heyer, Mathias Friebe, Jochen Seufert, Thomas Danne and Reinhard W. Holl

    Citation: Cardiovascular Diabetology 2019 18:33

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  6. Content type: Retraction Note

    The authors have retracted this article [1] because they have identified serious errors in their data analysis which change the conclusions of their study. All authors agree with this retraction.

    Authors: Kyoung Min Kim, Kyong Yeun Jung, Han Mi Yun, Seo Young Lee, Tae Jung Oh, Hak Chul Jang and Soo Lim

    Citation: Cardiovascular Diabetology 2019 18:32

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    The original article was published in Cardiovascular Diabetology 2017 16:146

  7. Content type: Original investigation

    Diabetes mellitus (DM) adversely affects morbidity and mortality for major atherosclerosis-related cardiovascular diseases and is associated with increased risk for the development of aortic stenosis. Clinical...

    Authors: Eilon Ram, Alexander Kogan, Shany Levin, Enrique Z. Fisman, Alexander Tenenbaum, Ehud Raanani and Leonid Sternik

    Citation: Cardiovascular Diabetology 2019 18:31

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  8. Content type: Commentary

    The 4th Cardiovascular Outcome Trial (CVOT) Summit of the Diabetes & Cardiovascular Disease (D&CVD) EASD Study Group was held in Munich on 25–26 October 2018. As in previous years, this summit served as a refe...

    Authors: Oliver Schnell, Eberhard Standl, Doina Catrinoiu, Baruch Itzhak, Nebojsa Lalic, Dario Rahelic, Jan Skrha, Paul Valensi and Antonio Ceriello

    Citation: Cardiovascular Diabetology 2019 18:30

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  9. Content type: Original investigation

    Cardiovascular autonomic neuropathy (CAN) is a major cause of morbidity and mortality in diabetes patients. Although several risk factors for CAN progression have been established, whether CAN is reversible re...

    Authors: Ji Eun Jun, Seung-Eun Lee, Min Sun Choi, Sung Woon Park, You-Cheol Hwang and Jae Hyeon Kim

    Citation: Cardiovascular Diabetology 2019 18:29

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  10. Content type: Original investigation

    To determine the impact of dipeptidyl peptidase-4 inhibitor (DPP4i) on the risk of major cardiocerebrovascular and renal outcomes compared with sulfonylurea (SU) combined with metformin in patients with type 2...

    Authors: Kyoung Jin Kim, Jimi Choi, Juneyoung Lee, Jae Hyun Bae, Jee Hyun An, Hee Young Kim, Hye Jin Yoo, Ji A. Seo, Nan Hee Kim, Kyung Mook Choi, Sei Hyun Baik, Sin Gon Kim and Nam Hoon Kim

    Citation: Cardiovascular Diabetology 2019 18:28

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  11. Content type: Original investigation

    Glycemic variability is associated with worse outcomes after cardiac surgery, but the prognosis value of early glycemic variability after transcatheter aortic valve implantation is not known. This study was th...

    Authors: Guillaume Besch, Sebastien Pili-Floury, Caroline Morel, Martine Gilard, Guillaume Flicoteaux, Lucie Salomon du Mont, Andrea Perrotti, Nicolas Meneveau, Sidney Chocron, Francois Schiele, Herve Le Breton, Emmanuel Samain and Romain Chopard

    Citation: Cardiovascular Diabetology 2019 18:27

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  12. Content type: Original investigation

    The prevalence of asymptomatic coronary artery disease (CAD) in type 2 diabetes (T2D) is unclear. We investigated the extent and prevalence of asymptomatic CAD in T2D patients by utilizing invasive coronary an...

    Authors: Satish Arora, Anne Pernille Ofstad, Geir R. Ulimoen, Kåre I. Birkeland, Knut Endresen, Lars Gullestad and Odd Erik Johansen

    Citation: Cardiovascular Diabetology 2019 18:26

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  13. Content type: Original investigation

    Percutaneous coronary intervention (PCI) in patients with diabetes mellitus (DM) remains challenging even with modern drug-eluting stents (DES) due to high rates of repeat revascularization. Everolimus-eluting...

    Authors: T. M. Hommels, R. S. Hermanides, S. Rasoul, B. Berta, A. J. J. IJsselmuiden, G. A. J. Jessurun, E. Benit, B. Pereira, G. De Luca and E. Kedhi

    Citation: Cardiovascular Diabetology 2019 18:25

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  14. Content type: Original investigation

    In patients with Normal Glucose Tolerance (NGT) some causes of ischemic heart disease (IHD) were not completely investigated. The role both of metabolic milieu and adipokines in IHD progression was not fully inve...

    Authors: Ferdinando Carlo Sasso, Pia Clara Pafundi, Raffaele Marfella, Paolo Calabrò, Federico Piscione, Fulvio Furbatto, Giovanni Esposito, Raffaele Galiero, Felice Gragnano, Luca Rinaldi, Teresa Salvatore, Michele D’Amico, Luigi Elio Adinolfi and Celestino Sardu

    Citation: Cardiovascular Diabetology 2019 18:24

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  15. Content type: Correction

    Following publication of the original article [1], based on the authors review, the GLP1 receptor agonists in type 2 diabetes published in Cardiovascular Diabetology, a meta-analysis of GLP-1 and non-GLP-1 bas...

    Authors: Andrei C. Sposito, Otávio Berwanger, Luiz Sérgio F. de Carvalho and José Francisco Kerr Saraiva

    Citation: Cardiovascular Diabetology 2019 18:23

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    The original article was published in Cardiovascular Diabetology 2018 17:157

  16. Content type: Original investigation

    Patients with type 2 diabetes mellitus are at an increased risk of adverse cardiovascular events compared to those without diabetes. The timing, relative to disease onset, and degree of glycemic control that r...

    Authors: Jaskanwal D. Sara, Riad Taher, Nikhil Kolluri, Adrian Vella, Lilach O. Lerman and Amir Lerman

    Citation: Cardiovascular Diabetology 2019 18:22

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  17. Content type: Original investigation

    There is a mutual interaction between inflammation and endocrine disorders in the development of coronary artery disease (CAD). Growth differentiation factor-15 (GDF-15) is associated with CAD, and the effects...

    Authors: Huan Liu, Yongnan Lyu, Di Li, Yan Cui, Yun Huang, Wen Dai and Yan Li

    Citation: Cardiovascular Diabetology 2019 18:21

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  18. Content type: Review

    Sotagliflozin is a dual sodium–glucose co-transporter-2 and 1 (SGLT2/1) inhibitor for the treatment of both type 1 (T1D) and type 2 diabetes (T2D). Sotagliflozin inhibits renal sodium–glucose co-transporter 2 ...

    Authors: Chiara Maria Assunta Cefalo, Francesca Cinti, Simona Moffa, Flavia Impronta, Gian Pio Sorice, Teresa Mezza, Alfredo Pontecorvi and Andrea Giaccari

    Citation: Cardiovascular Diabetology 2019 18:20

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  19. Content type: Original investigation

    Impaired glucose tolerance (IGT) is a risk factor for the development of diabetes and related complications that ensue. Early identification of at-risk individuals might be beneficial to reduce or delay the pr...

    Authors: Lucia La Sala, Simona Mrakic-Sposta, Elena Tagliabue, Francesco Prattichizzo, Stefano Micheloni, Elena Sangalli, Claudia Specchia, Anna Chiara Uccellatore, Silvia Lupini, Gaia Spinetti, Paola de Candia and Antonio Ceriello

    Citation: Cardiovascular Diabetology 2019 18:18

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  20. Content type: Original investigation

    Soluble Receptor for Advanced Glycation End Products (sRAGE) may be considered a marker inversely related to inflammation and its participation has been established in patients with advanced atherosclerotic va...

    Authors: Andrea Maria Maresca, Luigina Guasti, Sara Bozzini, Christian Mongiardi, Nicolò Tandurella, Rossana Corso, Francesco G. Zerba, Alessandro Squizzato, Leonardo Campiotti, Francesco Dentali, Catherine Klersy, Anna M. Grandi and Colomba Falcone

    Citation: Cardiovascular Diabetology 2019 18:17

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  21. Content type: Original investigation

    Sodium-glucose cotransporter 2 inhibitors (SGLT2i) is the first class of anti-diabetes treatment that reduces mortality and risk for hospitalization due to heart failure. In clinical studies it has been shown ...

    Authors: Damilola D. Adingupu, Sven O. Göpel, Julia Grönros, Margareta Behrendt, Matus Sotak, Tasso Miliotis, Ulrika Dahlqvist, Li-Ming Gan and Ann-Cathrine Jönsson-Rylander

    Citation: Cardiovascular Diabetology 2019 18:16

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  22. Content type: Original investigation

    Hyperglycaemia associated with myocardial oxidative stress and fibrosis is the main cause of diabetic cardiomyopathy. Empagliflozin, a sodium-glucose cotransporter 2 (SGLT2) inhibitor has recently been reporte...

    Authors: Chenguang Li, Jie Zhang, Mei Xue, Xiaoyu Li, Fei Han, Xiangyang Liu, Linxin Xu, Yunhong Lu, Ying Cheng, Ting Li, Xiaochen Yu, Bei Sun and Liming Chen

    Citation: Cardiovascular Diabetology 2019 18:15

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  23. Content type: Original investigation

    Carotid artery intima-media thickness (cIMT) progression is a surrogate marker of atherosclerosis with a high predictive value for future CVD risk. This study evaluates the comparative efficacies of lipid lowe...

    Authors: Rongzhong Huang, Kerry Mills, Julio Romero, Yan Li, Zicheng Hu, Yu Cao, Hua Huang, Yu Xu and Lihong Jiang

    Citation: Cardiovascular Diabetology 2019 18:14

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  24. Content type: Original investigation

    The diabetic heart undergoes remodelling contributing to an increased incidence of heart failure in individuals with diabetes at a later stage. The molecular regulators that drive this process in the diabetic ...

    Authors: Shruti Rawal, Prashanth Thevakar Nagesh, Sean Coffey, Isabelle Van Hout, Ivor F. Galvin, Richard W. Bunton, Philip Davis, Michael J. A. Williams and Rajesh Katare

    Citation: Cardiovascular Diabetology 2019 18:13

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  25. Content type: Original investigation

    Increasing evidence has suggested that the presence of remnant lipoproteins is a significant risk factor for atherosclerosis. Remnant lipoproteins are lipoproteins that are rich in triglycerides (TGs), and the...

    Authors: Zheng Qin, Kuo Zhou, Yue-ping Li, Jian-long Wang, Wan-jun Cheng, Cheng-ping Hu, Chao Shi, Hua He and Yu-jie Zhou

    Citation: Cardiovascular Diabetology 2019 18:11

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  26. Content type: Commentary

    Novel studies have increased our knowledge regarding optimal treatment options in diabetes. Key studies that have broadened our knowledge about optimal treatment options in diabetes in recent years are cardiov...

    Authors: Katharina Fritzen and Oliver Schnell

    Citation: Cardiovascular Diabetology 2019 18:10

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  27. Content type: Original investigation

    Reports on body mass index (BMI) trajectories from childhood into late adolescence, their determinants, and subsequent cardiometabolic risk markers, particularly among European populations have been few. Moreo...

    Authors: Kolade Oluwagbemigun, Anette E. Buyken, Ute Alexy, Matthias Schmid, Christian Herder and Ute Nöthlings

    Citation: Cardiovascular Diabetology 2019 18:9

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  28. Content type: Original investigation

    Serum haptoglobin (Hp) has been closely associated with cardio-cerebrovascular diseases. We investigated a metabolic profile associated with circulating Hp and carotid arterial functions via a targeted metabol...

    Authors: Shiyun Wang, Jie Wang, Rong Zhang, Aihua Zhao, Xiaojiao Zheng, Dandan Yan, Feng Jiang, Wei Jia, Cheng Hu and Weiping Jia

    Citation: Cardiovascular Diabetology 2019 18:8

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  29. Content type: Original investigation

    Metabolic abnormalities have been implicated as a causal event in diabetic cardiomyopathy (DCM). However, the mechanisms underlying cardiac metabolic disorder in DCM were not fully understood.

    Authors: Zhongwei Yin, Yanru Zhao, Mengying He, Huaping Li, Jiahui Fan, Xiang Nie, Mengwen Yan, Chen Chen and Dao Wen Wang

    Citation: Cardiovascular Diabetology 2019 18:7

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  30. Content type: Original investigation

    Sortilin is a 95-kDa protein which has recently been linked to circulating cholesterol concentration and lifetime risk of developing significant atherosclerotic disease. Sortilin is found inside different cell...

    Authors: Federico Biscetti, Nicola Bonadia, Francesco Santini, Flavia Angelini, Elisabetta Nardella, Dario Pitocco, Angelo Santoliquido, Marco Filipponi, Raffaele Landolfi and Andrea Flex

    Citation: Cardiovascular Diabetology 2019 18:5

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  31. Content type: Original investigation

    Diabetes mellitus (DM) is a prevalent metabolic disease characterized by chronic hyperglycemia. A primary burden of DM is related to its long-term complications, which have been shown to impact the course of h...

    Authors: Kassem Sharif, Suheil Ghadir, Daniela Jakubowicz, Howard Amital, Nicola Luigi Bragazzi, Abdulla Watad, Julio Wainstein and Yosefa Bar-Dayan

    Citation: Cardiovascular Diabetology 2019 18:4

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  32. Content type: Original investigation

    Epicardial fat tissue (EFT) is the visceral fat distributed along the coronary arteries between the pericardium and the myocardium. Increases in EFT are closely related to the occurrence of diabetes mellitus (...

    Authors: Yingrui Li, Bin Liu, Yu Li, Xiaodong Jing, Songbai Deng, Yulin Yan and Qiang She

    Citation: Cardiovascular Diabetology 2019 18:3

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  33. Content type: Original investigation

    The prognostic importance of carotid atherosclerosis in individuals with diabetes is unsettled. We aimed to evaluate the relationships between parameters of carotid atherosclerosis and the future occurrence of...

    Authors: Claudia R. L. Cardoso, Guilherme C. Salles, Nathalie C. Leite and Gil F. Salles

    Citation: Cardiovascular Diabetology 2019 18:2

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  34. Content type: Original investigation

    In heart failure the myocardium becomes insulin resistant which negatively influences cardiac energy metabolism and function, while increasing cardiac insulin signalling improves cardiac function and prevents ...

    Authors: Qutuba G. Karwi, Liyan Zhang, Cory S. Wagg, Wang Wang, Manoj Ghandi, Dung Thai, Hai Yan, John R. Ussher, Gavin Y. Oudit and Gary D. Lopaschuk

    Citation: Cardiovascular Diabetology 2019 18:1

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  35. Content type: Original investigation

    Several studies have shown that bariatric surgery reduces long term mortality compared to medical weight loss therapy. In a previous study we have demonstrated that gastric banding (LAGB) is associated with re...

    Authors: Antonio E. Pontiroli, Ahmed S. Zakaria, Marco Fanchini, Chiara Osio, Elena Tagliabue, Giancarlo Micheletto, Alessandro Saibene and Franco Folli

    Citation: Cardiovascular Diabetology 2018 17:161

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  36. Content type: Original investigation

    There are increasing evidence that left ventricle diastolic dysfunction is the initial functional alteration in the diabetic myocardium. In this study, we hypothesized that alogliptin prevents diastolic dysfun...

    Authors: Xiaowei Zhang, Zhiwei Zhang, Yajuan Yang, Ya Suo, Ruimeng Liu, Jiuchun Qiu, Yungang Zhao, Ning Jiang, Changle Liu, Gary Tse, Guangping Li and Tong Liu

    Citation: Cardiovascular Diabetology 2018 17:160

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  37. Content type: Correction

    Following publication of the original article [1], the authors reported an error in Acknowledgment section. The last sentence should read as “All authors have read and approval the submission to Cardiovascular...

    Authors: Celestino Sardu, Michelangela Barbieri, Maria Luisa Balestrieri, Mario Siniscalchi, Pasquale Paolisso, Paolo Calabrò, Fabio Minicucci, Giuseppe Signoriello, Michele Portoghese, Pasquale Mone, Davide D’Andrea, Felice Gragnano, Alessandro Bellis, Ciro Mauro, Giuseppe Paolisso, Maria Rosaria Rizzo…

    Citation: Cardiovascular Diabetology 2018 17:159

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    The original article was published in Cardiovascular Diabetology 2018 17:152

  38. Content type: Original investigation

    Patients with type 1 diabetes (T1DM) have increased mortality from cardiovascular disease (CVD). Risk factors for CVD include an elevation of LDL (LDLp) and small HDL (sHDLp) particles, and a decrease in rever...

    Authors: Evgenia Gourgari, Martin P. Playford, Umberto Campia, Amit K. Dey, Fran Cogen, Stephanie Gubb-Weiser, Mihriye Mete, Sameer Desale, Maureen Sampson, Allen Taylor, Kristina I. Rother, Alan T. Remaley and Nehal N. Mehta

    Citation: Cardiovascular Diabetology 2018 17:158

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  39. Content type: Review

    Patients with type 2 diabetes (T2DM) have a substantial risk of developing cardiovascular disease. The strong connection between the severity of hyperglycaemia, metabolic changes secondary to T2DM and vascular...

    Authors: Andrei C. Sposito, Otávio Berwanger, Luiz Sérgio F. de Carvalho and José Francisco Kerr Saraiva

    Citation: Cardiovascular Diabetology 2018 17:157

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    The Correction to this article has been published in Cardiovascular Diabetology 2019 18:23

  40. Content type: Original investigation

    The pathophysiology of cardiovascular complications in people with type 1 diabetes (T1DM) remains unclear. An increase in epicardial adipose tissue (EAT) and alterations in the composition of high-density lipo...

    Authors: Cristina Colom, David Viladés, Montserrat Pérez-Cuellar, Rubén Leta, Andrea Rivas-Urbina, Gemma Carreras, Jordi Ordóñez-Llanos, Antonio Pérez and Jose Luis Sánchez-Quesada

    Citation: Cardiovascular Diabetology 2018 17:156

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  41. Content type: Original investigation

    Increasing evidence suggest that statin therapy has a diabetogenic effect. Individual types of statin may have a different effect on glucose metabolism. Using the repeated nationwide population-based health sc...

    Authors: Jinkwon Kim, Hye Sun Lee and Kyung-Yul Lee

    Citation: Cardiovascular Diabetology 2018 17:155

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  42. Content type: Original investigation

    Epidemiological studies have demonstrated a relationship between cognitive function in youth and the future risk of death. Less is known regarding the relationship with diabetes related death. This study asses...

    Authors: Gilad Twig, Amir Tirosh, Estela Derazne, Ziona Haklai, Nehama Goldberger, Arnon Afek, Hertzel C. Gerstein, Jeremy D. Kark and Tali Cukierman-Yaffe

    Citation: Cardiovascular Diabetology 2018 17:154

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  43. Content type: Original investigation

    Deteriorated arterial function and high incidence of cardiovascular events characterise diabetes mellitus. Metformin and recent antidiabetic drugs, SGLT2 inhibitors, reduce cardiovascular events. We explored t...

    Authors: Mojca Lunder, Miodrag Janić, Miha Japelj, Andrej Juretič, Andrej Janež and Mišo Šabovič

    Citation: Cardiovascular Diabetology 2018 17:153

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  44. Content type: Original investigation

    We evaluate whether the thrombus aspiration (TA) before primary percutaneous coronary intervention (PPCI) may improve STEMI outcomes in hyperglycemic patients.

    Authors: Celestino Sardu, Michelangela Barbieri, Maria Luisa Balestrieri, Mario Siniscalchi, Pasquale Paolisso, Paolo Calabrò, Fabio Minicucci, Giuseppe Signoriello, Michele Portoghese, Pasquale Mone, Davide D’Andrea, Felice Gragnano, Alessandro Bellis, Ciro Mauro, Giuseppe Paolisso, Maria Rosaria Rizzo…

    Citation: Cardiovascular Diabetology 2018 17:152

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    The Correction to this article has been published in Cardiovascular Diabetology 2018 17:159

  45. Content type: Original investigation

    Type 2 diabetes mellitus (DM) is a frequent co-morbidity among patients undergoing coronary artery bypass grafting (CABG) surgery. The aim of this study was to evaluate the impact of DM on the early- and long-...

    Authors: Alexander Kogan, Eilon Ram, Shany Levin, Enrique Z. Fisman, Alexander Tenenbaum, Ehud Raanani and Leonid Sternik

    Citation: Cardiovascular Diabetology 2018 17:151

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  46. Content type: Original investigation

    The global prevalence of type 2 diabetes-related complications is not well described. We assessed prevalence of vascular complications at baseline in DISCOVER (NCT02322762; NCT02226822), a global, prospective,...

    Authors: Mikhail Kosiborod, Marilia B. Gomes, Antonio Nicolucci, Stuart Pocock, Wolfgang Rathmann, Marina V. Shestakova, Hirotaka Watada, Iichiro Shimomura, Hungta Chen, Javier Cid-Ruzafa, Peter Fenici, Niklas Hammar, Filip Surmont, Fengming Tang and Kamlesh Khunti

    Citation: Cardiovascular Diabetology 2018 17:150

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