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  1. Raised liver function tests (LFTs) have been correlated with multiple metabolic abnormalities and variably associated with cardiorenal outcomes. We sought to systematically test the relationship between LFT le...

    Authors: Giulia Ferrannini, Norman Rosenthal, Michael K. Hansen and Ele Ferrannini
    Citation: Cardiovascular Diabetology 2022 21:127
    Content type: Research Published on:

  2. Outcome prediction tools for patients with type 2 diabetes mellitus (T2DM) undergoing percutaneous coronary intervention (PCI) are lacking. Here, we developed a machine learning-based metabolite classifier for...

    Authors: Xue-bin Wang, Ning-hua Cui and Xia’nan Liu
    Citation: Cardiovascular Diabetology 2022 21:126
    Content type: Research Published on:

  3. Obesity is strongly associated with the development of cardiovascular disease (CVD). However, the heterogenous nature of obesity in CVD-risk is still poorly understood. We aimed to explore novel CVD biomarkers...

    Authors: Johan Korduner, Hannes Holm, Amra Jujic, Olle Melander, Manan Pareek, John Molvin, Lennart Råstam, Ulf Lindblad, Bledar Daka, Margret Leosdottir, Peter M. Nilsson, Erasmus Bachus, Michael H. Olsen and Martin Magnusson
    Citation: Cardiovascular Diabetology 2022 21:125
    Content type: Research Published on:

  4. The triglyceride-glucose (TyG) index is a new alternative measure for insulin resistance. This meta-analysis was conducted to assess the associations of the TyG index with the risks of cardiovascular diseases ...

    Authors: Xiao Liu, Ziqi Tan, Yuna Huang, Huilei Zhao, Menglu Liu, Peng Yu, Jianyong Ma, Yujie Zhao, Wengen Zhu and Jingfeng Wang
    Citation: Cardiovascular Diabetology 2022 21:124
    Content type: Review Published on:

  5. Insulin resistance (IR), endothelial dysfunction, inflammation, glucose and lipid metabolism disorders, and thrombosis are believed involved in coronary heart disease (CHD) and non-alcoholic fatty liver diseas...

    Authors: Jianqi Zhao, Hongxuan Fan, Ting Wang, Bing Yu, Shaobin Mao, Xun Wang, Wenjing Zhang, Leigang Wang, Yao Zhang, Zhaoyu Ren and Bin Liang
    Citation: Cardiovascular Diabetology 2022 21:123
    Content type: Research Published on:

  6. Diabetes is a metabolic disorder that affects millions of people worldwide. Diabetic heart disease (DHD) comprises coronary artery disease, heart failure, cardiac autonomic neuropathy, peripheral arterial dise...

    Authors: Dhananjie Chandrasekera and Rajesh Katare
    Citation: Cardiovascular Diabetology 2022 21:122
    Content type: Review Published on:

  7. In statins-treated diabetic mellitus (DM) patients, longitudinal coronary CTA (CCTA) evidence is scarce regarding the relationship between coronary Agatston artery calcification scores (CACs) and coronary plaq...

    Authors: Rui Shi, Yue Gao, Li-Ling Shen, Ke Shi, Jin Wang, Li Jiang, Yuan Li and Zhi-Gang Yang
    Citation: Cardiovascular Diabetology 2022 21:121
    Content type: Research Published on:

  8. Type 2 diabetes mellitus (DM) is a frequent co-morbidity among patients suffering from infective endocarditis (IE). The aim of the study was to evaluate the impact of type 2 DM on the early-, intermediate- and...

    Authors: Alexander Kogan, Anat Wieder-Finesod, Jonathan Frogel, Yael Peled-Potashnik, Eilon Ram, Ehud Raanani and Leonid Sternik
    Citation: Cardiovascular Diabetology 2022 21:120
    Content type: Research Published on:

  9. Atrial fibrillation, the most common cardiac arrhythmia, results in substantial morbidity and mortality related to its increased risks of stroke, heart failure, and impaired cognitive function. The incidence a...

    Authors: Syona S Shetty and Andrew Krumerman
    Citation: Cardiovascular Diabetology 2022 21:119
    Content type: Review Published on:

  10. Although a few meta-analyses were conducted to compare the risk of incident atrial fibrillation (AF) between sodium-glucose cotransporter-2 inhibitor (SGLT2i), glucagon-like peptide-1 receptor agonists (GLP-1R...

    Authors: Yi-Hsin Chan, Tze-Fan Chao, Shao-Wei Chen, Hsin-Fu Lee, Pei-Ru Li, Wei-Min Chen, Yung-Hsin Yeh, Chi-Tai Kuo, Lai-Chu See and Gregory Y. H. Lip
    Citation: Cardiovascular Diabetology 2022 21:118
    Content type: Research Published on:

  11. Previous research has linked elevated low-density lipoprotein cholesterol (LDL-C) and remnant cholesterol (RC) with diabetes mellitus (DM). The present study aims to estimate the RC-related DM risk beyond LDL-...

    Authors: Xiangming Hu, Qunzhi Liu, Xingyuan Guo, Weimian Wang, Bingyan Yu, Beijia Liang, Yingling Zhou, Haojian Dong and Jijin Lin
    Citation: Cardiovascular Diabetology 2022 21:117
    Content type: Research Published on:

  12. To determine whether there were racial differences in short-term cardiometabolic responses to once-weekly exenatide (EQW) in the Exenatide Study of Cardiovascular Event Lowering (EXSCEL).

    Authors: Timothy M. E. Davis, Anna Giczewska, Yuliya Lokhnygina, Robert J. Mentz, Naveed Sattar and Rury R. Holman
    Citation: Cardiovascular Diabetology 2022 21:116
    Content type: Research Published on:

  13. The residual SYNTAX score (rSS), a quantitative measure of angiographic completeness of revascularization after percutaneous coronary intervention (PCI), and the triglyceride–glucose index (TyG index), a relia...

    Authors: Shiqiang Xiong, Qiang Chen, Zhen Zhang, Yingzhong Chen, Jun Hou, Caiyan Cui, Lianchao Cheng, Hong Su, Yu Long, Siqi Yang, Lingyao Qi, Xu Chen, Hanxiong Liu and Lin Cai
    Citation: Cardiovascular Diabetology 2022 21:115
    Content type: Research Published on:

  14. Admission hyperglycemia is associated with poor prognosis in patients with acute myocardial infarction (AMI), but the effects of baseline diabetes status on this association remain elusive. We aim to investiga...

    Authors: Hanzohra Upur, Jia-Li Li, Xiao-Guang Zou, Yu-Ying Hu, He-Yin Yang, Alimujiang Abudoureyimu, Anwar Abliz, Mamatili Abdukerim and Min Huang
    Citation: Cardiovascular Diabetology 2022 21:114
    Content type: Research Published on:

  16. We evaluated whether measures of glucose dysregulation are associated with subclinical cardiac dysfunction, as assessed by speckle-tracking echocardiography, in an older population.

    Authors: Parveen K. Garg, Mary L. Biggs, Jorge R. Kizer, Sanjiv J. Shah, Bruce Psaty, Mercedes Carnethon, John S. Gottdiener, David Siscovick and Kenneth J. Mukamal
    Citation: Cardiovascular Diabetology 2022 21:112
    Content type: Research Published on:

  18. Compared with enalapril, sacubitril/valsartan lowered HbA1c and reduced new insulin therapy in patients with heart failure with reduced ejection fraction (HFrEF) and diabetes in the PARADIGM-HF trial. We sough...

    Authors: Magnus O. Wijkman, Brian Claggett, Muthiah Vaduganathan, Jonathan W. Cunningham, Rasmus Rørth, Alice Jackson, Milton Packer, Michael Zile, Jean Rouleau, Karl Swedberg, Martin Lefkowitz, Sanjiv J. Shah, Marc A. Pfeffer, John J. V. McMurray and Scott D. Solomon
    Citation: Cardiovascular Diabetology 2022 21:110
    Content type: Research Published on:

  19. Adverse ventricular structure and function is a key pathogenic mechanism of heart failure. Observational studies have shown that both insulin resistance (IR) and glycemic level are associated with adverse vent...

    Authors: Sizhi Ai, Xiaoyu Wang, Shanshan Wang, Yilin Zhao, Shuxun Guo, Guohua Li, Zhigang Chen, Fei Lin, Sheng Guo, Yan Li, Jihui Zhang and Guoan Zhao
    Citation: Cardiovascular Diabetology 2022 21:109
    Content type: Research Published on:

  20. Findings from the T.O.S.CA. Registry recently reported that patients with concomitant chronic heart failure (CHF) and impairment of insulin axis (either insulin resistance—IR or diabetes mellitus—T2D) display ...

    Authors: Andrea Salzano, Roberta D’Assante, Massimo Iacoviello, Vincenzo Triggiani, Giuseppe Rengo, Francesco Cacciatore, Ciro Maiello, Giuseppe Limongelli, Daniele Masarone, Angela Sciacqua, Pasquale Perrone Filardi, Antonio Mancini, Maurizio Volterrani, Olga Vriz, Roberto Castello, Andrea Passantino…
    Citation: Cardiovascular Diabetology 2022 21:108
    Content type: Research Published on:

  21. The Food and Drug Administration has approved Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) inhibitors for the treatment of dyslipidemia. However, evidence of the optimal PCSK9 agents targeting PCSK9 f...

    Authors: Xing Wang, Dingke Wen, Yuqi Chen, Lu Ma and Chao You
    Citation: Cardiovascular Diabetology 2022 21:107
    Content type: Research Published on:

  22. Empagliflozin has been reported to protect endothelial cell function, regardless of diabetes status. However, the role of empagliflozin in microvascular protection during myocardial ischemia reperfusion injury...

    Authors: Rongjun Zou, Wanting Shi, Junxiong Qiu, Na Zhou, Na Du, Hao Zhou, Xinxin Chen and Li Ma
    Citation: Cardiovascular Diabetology 2022 21:106
    Content type: Research Published on:

  23. Recent studies have suggested that triglyceride-glucose (TyG) index is an independent predictor of cardiovascular disease (CVD). However, the impact of long-term visit-to-visit variability in TyG index on the ...

    Authors: Haibin Li, Yingting Zuo, Frank Qian, Shuohua Chen, Xue Tian, Penglian Wang, Xia Li, Xiuhua Guo, Shouling Wu and Anxin Wang
    Citation: Cardiovascular Diabetology 2022 21:105
    Content type: Research Published on:

  24. Type-2 diabetes (T2D), chronic kidney disease, and heart failure (HF) share epidemiological and pathophysiological features. Although their prevalence was described, there is limited contemporary, high-resolut...

    Authors: Meir Schechter, Cheli Melzer Cohen, Ilan Yanuv, Aliza Rozenberg, Gabriel Chodick, Johan Bodegård, Lawrence A. Leiter, Subodh Verma, Hiddo J. Lambers Heerspink, Avraham Karasik and Ofri Mosenzon
    Citation: Cardiovascular Diabetology 2022 21:104
    Content type: Research Published on:

  25. Coronary artery disease (CAD) detection in asymptomatic patients still remains controversial. The aim of our study was to evaluate the usefulness of ophthalmologic findings as predictors of the presence of CAD...

    Authors: José Lorenzo Romero-Trevejo, Lourdes Fernández-Romero, Josué Delgado, Erika Muñoz-García, Andrés Sánchez-Pérez, Mora Murri, Mario Gutiérrez-Bedmar and Manuel Francisco Jiménez-Navarro
    Citation: Cardiovascular Diabetology 2022 21:103
    Content type: Research Published on:

  26. Assessing the spectrum of disease risk associated with hypertriglyceridemia is needed to inform potential benefits from emerging triglyceride lowering treatments. We sought to examine the associations between ...

    Authors: Riyaz S. Patel, Laura Pasea, Handrean Soran, Paul Downie, Richard Jones, Aroon D. Hingorani, Dermot Neely, Spiros Denaxas and Harry Hemingway
    Citation: Cardiovascular Diabetology 2022 21:102
    Content type: Research Published on:

  27. Heart failure (HF) is a growing complication and one of the leading causes of mortality in people living with type 2 diabetes (T2D). Among the possible causes, the excess of red meat and the insufficiency of v...

    Authors: Matthieu Wargny, Mikaël Croyal, Stéphanie Ragot, Elise Gand, David Jacobi, Jean-Noël Trochu, Xavier Prieur, Cédric Le May, Thomas Goronflot, Bertrand Cariou, Pierre-Jean Saulnier and Samy Hadjadj
    Citation: Cardiovascular Diabetology 2022 21:101
    Content type: Research Published on:

  28. Functional mitral regurgitation (FMR) in type 2 diabetes mellitus (T2DM) patients induced by left ventricular (LV) enlargement and mitral valve abnormality may aggravated the impairment in left atrial (LA) com...

    Authors: Yi Zhang, Xue-Ming Li, Meng-Ting Shen, Shan Huang, Yuan Li and Zhi-Gang Yang
    Citation: Cardiovascular Diabetology 2022 21:100
    Content type: Research Published on:

  29. Endothelin-1 (ET-1) and adrenomedullin (ADM) are commonly known as vasoactive peptides that regulate vascular homeostasis. Less recognised is the fact that both peptides could affect glucose metabolism. Here, ...

    Authors: Chaterina Sujana, Veikko Salomaa, Frank Kee, Jochen Seissler, Pekka Jousilahti, Charlotte Neville, Cornelia Then, Wolfgang Koenig, Kari Kuulasmaa, Jaakko Reinikainen, Stefan Blankenberg, Tanja Zeller, Christian Herder, Ulrich Mansmann, Annette Peters and Barbara Thorand
    Citation: Cardiovascular Diabetology 2022 21:99
    Content type: Research Published on:

  30. The association between osteocalcin and mortality has been scantly studied. We aimed to investigate the association between osteocalcin along with its trajectories and mortality based on long-term longitudinal...

    Authors: Yun Shen, Lei Chen, Jian Zhou, Chunfang Wang, Fei Gao, Wei Zhu, Gang Hu, Xiaojing Ma, Han Xia and Yuqian Bao
    Citation: Cardiovascular Diabetology 2022 21:98
    Content type: Research Published on:

  31. Arterial stiffness is a potential biomarker for cardiovascular disease (CVD) risk in patients with type 1 diabetes (T1D). However, its relation with other CV risk evaluation tools in T1D has not been elucidate...

    Authors: Simon Helleputte, Luc Van Bortel, Francis Verbeke, Jos Op ‘t Roodt, Patrick Calders, Bruno Lapauw and Tine De Backer
    Citation: Cardiovascular Diabetology 2022 21:97
    Content type: Research Published on:

  32. Triglyceride glucose (TyG) index is a new marker associated with atherosclerosis. This study aimed to assess the association between TyG index and the severity of coronary artery disease (CAD) in patients with...

    Authors: Jinyu Su, Zhu Li, Mengnan Huang, Yang Wang, Tong Yang, Mei Ma, Tongyao Ni, Guangwei Pan, Ziqin Lai, Chunjie Li, Lin Li and Chunquan Yu
    Citation: Cardiovascular Diabetology 2022 21:96
    Content type: Research Published on:

  33. Advanced glycation end-products (AGEs) and their interaction with the receptor for advanced glycation end-products (RAGE) play a pivotal role in the development and progression of type 2 diabetes. In this retr...

    Authors: Jacopo Sabbatinelli, Stefania Castiglione, Federica Macrì, Angelica Giuliani, Deborah Ramini, Maria Cristina Vinci, Elena Tortato, Anna Rita Bonfigli, Fabiola Olivieri and Angela Raucci
    Citation: Cardiovascular Diabetology 2022 21:95
    Content type: Research Published on:

  34. Type 2 diabetes mellitus (T2DM) increases the risk of worse long-term outcomes in patients with non-ischemic dilated cardiomyopathy (NIDCM). However, the additive effects of T2DM on left ventricular (LV) funct...

    Authors: Meng-Ting Shen, Yuan Li, Ying-Kun Guo, Li Jiang, Yue Gao, Rui Shi and Zhi-Gang Yang
    Citation: Cardiovascular Diabetology 2022 21:94
    Content type: Research Published on:

  35. Type 2 diabetes mellitus (T2DM) is often accompanied by undiagnosed dyslipidemia. Research on the association of unconventional lipid markers with prediabetes (pre-DM) and T2DM simultaneously is limited in cor...

    Authors: Tong Yang, Yijia Liu, Lin Li, Yanchao Zheng, Yang Wang, Jinyu Su, Rongrong Yang, Mingchi Luo and Chunquan Yu
    Citation: Cardiovascular Diabetology 2022 21:93
    Content type: Research Published on:

  36. Sodium-glucose cotransporter-2 inhibitors (SGLT2i) have proven cardiovascular benefits in patients with type 2 diabetes (T2D). This self-controlled case series study aims to evaluate whether metformin use and ...

    Authors: Carlos King Ho Wong, Kristy Tsz Kwan Lau, Eric Ho Man Tang, Chi Ho Lee, Carmen Yu Yan Lee, Yu Cho Woo, Ivan Chi Ho Au, Kathryn Choon Beng Tan and David Tak Wai Lui
    Citation: Cardiovascular Diabetology 2022 21:92
    Content type: Research Published on:

  37. Red blood cell distribution width (RDW) has emerged as a prognostic factor for mortality in various diseases. Up to now, few studies have focused on the prognostic value of RDW in patients with diabetic foot u...

    Authors: Jing Hong, Xiang Hu, Wenyue Liu, Xuehua Qian, Feifei Jiang, Zeru Xu, Feixia Shen and Hong Zhu
    Citation: Cardiovascular Diabetology 2022 21:91
    Content type: Research Published on:

  38. To determine the impact of metabolic syndrome (MetS) and/or metabolic dysfunction-associated fatty liver disease (MAFLD), which are pathophysiologically similar and include insulin resistance, on the developme...

    Authors: Yasuhiro Matsubayashi, Kazuya Fujihara, Mayuko Yamada-Harada, Yurie Mitsuma, Takaaki Sato, Yuta Yaguchi, Taeko Osawa, Masahiko Yamamoto, Masaru Kitazawa, Takaho Yamada, Satoru Kodama and Hirohito Sone
    Citation: Cardiovascular Diabetology 2022 21:90
    Content type: Research Published on:

  39. Cardiovascular prognosis related to type 2 diabetes may not be adequately captured by information on comorbid conditions such as obesity and hypertension. To inform the cardiovascular prognosis among diabetic ...

    Authors: Justin B. Echouffo-Tcheugui, Solomon K. Musani, Alain G. Bertoni, Adolfo Correa, Ervin R. Fox and Robert J. Mentz
    Citation: Cardiovascular Diabetology 2022 21:89
    Content type: Research Published on:

  40. The triglyceride glucose (TyG) index has been proposed as a reliable marker of insulin resistance (IR) and an independent predictor of cardiovascular disease risk. However, its prognostic value in patients wit...

    Authors: Rong Huang, Ziyan Wang, Jianzhou Chen, Xue Bao, Nanjiao Xu, Simin Guo, Rong Gu, Weimin Wang, Zhonghai Wei and Lian Wang
    Citation: Cardiovascular Diabetology 2022 21:88
    Content type: Research Published on:

  41. Patients diagnosed with ischemic heart disease (IHD) are becoming increasingly multi-morbid, and studies designed to analyze the full spectrum are few.

    Authors: Amalie D. Haue, Jose J. Almagro Armenteros, Peter C. Holm, Robert Eriksson, Pope L. Moseley, Lars V. Køber, Henning Bundgaard and Søren Brunak
    Citation: Cardiovascular Diabetology 2022 21:87
    Content type: Research Published on:

  42. Hemoglobin A1C (HbA1c) is a form of glycated hemoglobin used to estimate glycemic control in diabetic patients. Data regarding the prognostic significance of HbA1c levels in contemporary intensive cardiac care...

    Authors: Lior Lupu, Louay Taha, Rivka Farkash, Feras Bayya, Mohammad Karmi, Yoed Steinmetz, Fauzi Fadi Shaheen, Nimrod Perel, Kamal Hamayel, Nir Levi, Tommer Maller, Hani Karameh, Gavriel Lichewitz, Dov Gavish, Nurit Algur, Michael Glikson…
    Citation: Cardiovascular Diabetology 2022 21:86
    Content type: Research Published on:

  43. Type 2 diabetes (T2D) and hypertension commonly coexist and are associated with subclinical myocardial structural and functional changes. We sought to determine the association between blood pressure (BP) and ...

    Authors: Jian L. Yeo, Gaurav S. Gulsin, Emer M. Brady, Abhishek Dattani, Joanna M. Bilak, Anna-Marie Marsh, Manjit Sian, Lavanya Athithan, Kelly S. Parke, Joanne Wormleighton, Matthew P. M. Graham-Brown, Anvesha Singh, J. Ranjit Arnold, Claire Lawson, Melanie J. Davies, Hui Xue…
    Citation: Cardiovascular Diabetology 2022 21:85
    Content type: Research Published on:

  46. Statin treatment increases the risk of new-onset diabetes mellitus (NODM); however, data directly comparing the risk of NODM among individual statins is limited. We compared the risk of NODM between patients u...

    Authors: Won-Woo Seo, Seung In Seo, Yerim Kim, Jong Jin Yoo, Woon Geon Shin, Jinseob Kim, Seng Chan You, Rae Woong Park, Young Min Park, Kyung-Jin Kim, Sang Youl Rhee, Meeyoung Park, Eun-Sun Jin and Sung Eun Kim
    Citation: Cardiovascular Diabetology 2022 21:82
    Content type: Research Published on:

  47. The atherogenic index of plasma (AIP) is composed of triglycerides and high-density lipoprotein cholesterol and is a novel marker for assessing the risk of atherogenicity and cardiometabolic health. An associa...

    Authors: Si Hyoung Kim, Yun Kyung Cho, Ye-Jee Kim, Chang Hee Jung, Woo Je Lee, Joong-Yeol Park, Ji Hye Huh, Jun Goo Kang, Seong Jin Lee and Sung-Hee Ihm
    Citation: Cardiovascular Diabetology 2022 21:81
    Content type: Research Published on:

  48. Proprotein convertase subtilisin/kexin type 9 (PCSK9) has been shown to be predictive of cardiovascular outcomes in stable coronary artery disease with diabetes. We aimed to assess the relationship between PCS...

    Authors: Li Song, Xiaoxiao Zhao, Runzhen Chen, Jiannan Li, Jinying Zhou, Chen Liu, Peng Zhou, Ying Wang, Yi Chen, Hanjun Zhao and Hongbing Yan
    Citation: Cardiovascular Diabetology 2022 21:80
    Content type: Research Published on:

  49. In patients with type 2 diabetes mellitus (T2DM) an association between severe hypoglycaemic episodes and the risk of cardiovascular (CV) morbidity and mortality has been previously established.

    Authors: Ceren Eyileten, Zofia Wicik, Disha Keshwani, Faisal Aziz, Felix Aberer, Peter N. Pferschy, Norbert J. Tripolt, Caren Sourij, Barbara Prietl, Florian Prüller, Dirk von Lewinski, Salvatore De Rosa, Jolanta M. Siller-Matula, Marek Postula and Harald Sourij
    Citation: Cardiovascular Diabetology 2022 21:79
    Content type: Research Published on:

  50. There have been scarce data comparing cardiovascular outcomes between individual sodium-glucose cotransporter-2 (SGLT2) inhibitors. We aimed to compare the subsequent cardiovascular risk between individual SGL...

    Authors: Yuta Suzuki, Hidehiro Kaneko, Akira Okada, Hidetaka Itoh, Satoshi Matsuoka, Katsuhito Fujiu, Nobuaki Michihata, Taisuke Jo, Norifumi Takeda, Hiroyuki Morita, Kentaro Kamiya, Atsuhiko Matsunaga, Junya Ako, Koichi Node, Hideo Yasunaga and Issei Komuro
    Citation: Cardiovascular Diabetology 2022 21:67
    Content type: Research Published on:
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ISSN: 1475-2840