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Cardiovascular Diabetology

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  1. Content type: Original investigation

    Coronary atherosclerosis progresses faster in patients with diabetes mellitus (DM) and causes higher morbidity and mortality in such patients compared to non-diabetics ones (non-DM). We quantify changes in pla...

    Authors: Tomas Kovarnik, Zhi Chen, Gary S. Mintz, Andreas Wahle, Kristyna Bayerova, Ales Kral, Martin Chval, Karel Kopriva, John Lopez, Milan Sonka and Ales Linhart

    Citation: Cardiovascular Diabetology 2017 16:156

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  2. Content type: Review

    Cardiovascular disease, predominantly ischemic heart disease (IHD), is the leading cause of death in diabetes mellitus (DM). In addition to eliciting cardiomyopathy, DM induces a ‘wicked triumvirate’: (i) incr...

    Authors: Jake Russell, Eugene F. Du Toit, Jason N. Peart, Hemal H. Patel and John P. Headrick

    Citation: Cardiovascular Diabetology 2017 16:155

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  3. Content type: Original investigation

    Patients with type 2 diabetes (T2DM) are at high risk for cardiovascular events, which usually arise from the rupture of a vulnerable coronary plaque. The minimal fibrous cap thickness (FCT) overlying a necrot...

    Authors: Andrea Milzi, Mathias Burgmaier, Kathrin Burgmaier, Martin Hellmich, Nikolaus Marx and Sebastian Reith

    Citation: Cardiovascular Diabetology 2017 16:152

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  4. Content type: Original investigation

    The potential of anti-aging effect of DPP-4 inhibitors is unknown. This study was performed to determine whether linagliptin, a DPP-4 inhibitor, could protect against premature aging in klotho−/− mice.

    Authors: Yu Hasegawa, Kenyu Hayashi, Yushin Takemoto, Cao Cheng, Koki Takane, Bowen Lin, Yoshihiro Komohara and Shokei Kim-Mitsuyama

    Citation: Cardiovascular Diabetology 2017 16:154

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  5. Content type: Original investigation

    Biomarkers of inflammation and adiponectin are associated with cardiovascular autonomic neuropathy (CAN) in cross-sectional studies, but prospective data are scarce. This study aimed to assess the associations...

    Authors: Christian Stevns Hansen, Dorte Vistisen, Marit Eika Jørgensen, Daniel R. Witte, Eric J. Brunner, Adam G. Tabák, Mika Kivimäki, Michael Roden, Marek Malik and Christian Herder

    Citation: Cardiovascular Diabetology 2017 16:153

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  6. Content type: Original investigation

    Diabetes mellitus is considered an important risk factor for cardiovascular diseases. High hemoglobin A1c (HbA1c) levels, which indicate poor glycemic control, have been associated with occurrence of cardiovas...

    Authors: Shohei Ouchi, Kazunori Shimada, Tetsuro Miyazaki, Shuhei Takahashi, Yurina Sugita, Megumi Shimizu, Azusa Murata, Tomoyasu Kadoguchi, Takao Kato, Tatsuro Aikawa, Shoko Suda, Eiryu Sai, Masaru Hiki, Hiroshi Iwata, Takatoshi Kasai, Katsumi Miyauchi…

    Citation: Cardiovascular Diabetology 2017 16:151

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  7. Content type: Correction

    Following publication of the original article [1], the authors identified a number of errors. In Result (P.3), Table 1 (P.4), Table 5 (P.9) and Supplementary Table 1, the correct unit for adiponectin was μg/mL. I...

    Authors: Toshiyuki Hayashi, Tomoyasu Fukui, Noriko Nakanishi, Saki Yamamoto, Masako Tomoyasu, Anna Osamura, Makoto Ohara, Takeshi Yamamoto, Yasuki Ito and Tsutomu Hirano

    Citation: Cardiovascular Diabetology 2017 16:149

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    The original article was published in Cardiovascular Diabetology 2017 16:8

  8. Content type: Original investigation

    The cardiovascular benefits of statins have been proven, but their effect on circulation in small vessels has not been examined fully. We investigated the effect of 20 mg rosuvastatin on biomarkers, including ...

    Authors: Kyoung Min Kim, Kyong Yeun Jung, Han Mi Yun, Seo Young Lee, Tae Jung Oh, Hak Chul Jang and Soo Lim

    Citation: Cardiovascular Diabetology 2017 16:146

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  9. Content type: Original investigation

    Hypoglycemia is associated with increased mortality rate in patients with diabetes. The underlying mechanisms may involve reduced myocardial tolerance to ischemia and reperfusion (IR) or reduced capacity for i...

    Authors: Kim B. Pælestik, Nichlas R. Jespersen, Rebekka V. Jensen, Jacob Johnsen, Hans Erik Bøtker and Steen B. Kristiansen

    Citation: Cardiovascular Diabetology 2017 16:148

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  10. Content type: Original investigation

    Coexistence of left ventricular (LV) longitudinal myocardial systolic dysfunction with LV diastolic dysfunction could lead to heart failure with preserved ejection fraction (HFpEF). Diabetes mellitus (DM) is k...

    Authors: Makiko Suto, Hidekazu Tanaka, Yasuhide Mochizuki, Jun Mukai, Hiroki Takada, Fumitaka Soga, Kumiko Dokuni, Yutaka Hatani, Keiko Hatazawa, Hiroki Matsuzoe, Hiroyuki Sano, Hiroyuki Shimoura, Junichi Ooka, Kensuke Matsumoto, Yushi Hirota, Wataru Ogawa…

    Citation: Cardiovascular Diabetology 2017 16:145

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  11. Content type: Original investigation

    Irisin is a hormone released mainly from skeletal muscle after exercise which increases adipose tissue energy expenditure. Adipocytes can also release irisin after exercise, acting as a local adipokine to indu...

    Authors: Karan S. Rana, Chathyan Pararasa, Islam Afzal, David A. Nagel, Eric J. Hill, Clifford J. Bailey, Helen R. Griffiths, Ioannis Kyrou, Harpal S. Randeva, Srikanth Bellary and James E. Brown

    Citation: Cardiovascular Diabetology 2017 16:147

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  12. Content type: Original investigation

    Type 2 diabetes mellitus (T2DM) is strongly related to the in-hospital and short-term prognosis in patients with cardiovascular diseases needing surgical or invasive interventions. How T2DM might influence the...

    Authors: Manuel Mendez-Bailon, Noel Lorenzo-Villalba, Nuria Muñoz-Rivas, Jose Maria de Miguel-Yanes, Javier De Miguel-Diez, Josep Comín-Colet, Valentin Hernandez-Barrera, Rodrigo Jimenez-Garcia and Ana Lopez-de-Andres

    Citation: Cardiovascular Diabetology 2017 16:144

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  13. Content type: Original investigation

    Macrophages play a pivotal role in atherosclerotic plaque development. Recent evidence has suggested the glucagon-like peptide-1 receptor (GLP-1R) agonist, liraglutide, can attenuate pro-inflammatory responses...

    Authors: Robyn Bruen, Sean Curley, Sarina Kajani, Daniel Crean, Marcella E. O’Reilly, Margaret B. Lucitt, Catherine G. Godson, Fiona C. McGillicuddy and Orina Belton

    Citation: Cardiovascular Diabetology 2017 16:143

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  14. Content type: Original investigation

    Diabetes mellitus is a risk factor for coronary artery disease and diabetic cardiomyopathy, and adversely impacts outcomes following coronary artery bypass grafting. Current treatments focus on macro-revascula...

    Authors: Masashi Kawamura, Michael J. Paulsen, Andrew B. Goldstone, Yasuhiro Shudo, Hanjay Wang, Amanda N. Steele, Lyndsay M. Stapleton, Bryan B. Edwards, Anahita Eskandari, Vi N. Truong, Kevin J. Jaatinen, Arnar B. Ingason, Shigeru Miyagawa, Yoshiki Sawa and Y. Joseph Woo

    Citation: Cardiovascular Diabetology 2017 16:142

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  15. Content type: Original investigation

    We have previously shown that many chronic, inflammatory diseases are accompanied, and possibly partly caused or exacerbated, by various coagulopathies, manifested as anomalous clots in the form of ‘dense matt...

    Authors: Etheresia Pretorius, Martin J. Page, Lize Engelbrecht, Graham C. Ellis and Douglas B. Kell

    Citation: Cardiovascular Diabetology 2017 16:141

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  16. Content type: Original investigation

    Pioglitazone (PIO), a thiazolidinediones drug, is a well-known anti-diabetic medicine, but its anti-atherosclerotic effects remain controversial. Thus it is important to investigate the effects of PIO on ather...

    Authors: Yuling Tian, Tao Chen, Yan Wu, Lin Yang, Lijun Wang, Xiaojuan Fan, Wei Zhang, Jiahao Feng, Hang Yu, Yanjie Yang, Juan Zhou, Zuyi Yuan and Yue Wu

    Citation: Cardiovascular Diabetology 2017 16:140

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  17. Content type: Original investigation

    Altered regulation of extracellular matrix (ECM) composition by matrix metalloproteinases (MMPs) and tissue inhibitors of metalloproteinase (TIMPs) may contribute to arterial stiffening. We investigated associ...

    Authors: Stijn A. Peeters, Lian Engelen, Jacqueline Buijs, Nish Chaturvedi, John H. Fuller, Anders Jorsal, Hans-Henrik Parving, Lise Tarnow, Simone Theilade, Peter Rossing, Casper G. Schalkwijk and Coen D. A. Stehouwer

    Citation: Cardiovascular Diabetology 2017 16:139

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  18. Content type: Original investigation

    Sodium-glucose cotransporter-2 inhibitors reduce blood pressure (BP) and renal and cardiovascular events in patients with type 2 diabetes through not fully elucidated mechanisms. Aim of this study was to inves...

    Authors: Anna Solini, Livia Giannini, Marta Seghieri, Edoardo Vitolo, Stefano Taddei, Lorenzo Ghiadoni and Rosa Maria Bruno

    Citation: Cardiovascular Diabetology 2017 16:138

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  19. Content type: Review

    These recommendations aim to improve care for patients with type 2 diabetes (T2D) at high cardiovascular (CV) risk in Central and Eastern Europe. Cardiovascular disease (CVD) and/or chronic kidney disease (CKD...

    Authors: Guntram Schernthaner, Roger Lehmann, Martin Prázný, Leszek Czupryniak, Kristine Ducena, Peter Fasching, Andrej Janež, Avraham Karasik, Peter Kempler, Emil Martinka, Marina V. Shestakova, Lea Smirčić Duvnjak and Tsvetalina Tankova

    Citation: Cardiovascular Diabetology 2017 16:137

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  20. Content type: Correction

    This article was unintentionally published twice in this journal, by the same authors. The following should be considered the version of record and used for citation purposes: “Mehran Haidari, Wei Zhang, James...

    Authors: Mehran Haidari, Wei Zhang, James T. Willerson and Richard A. F. Dixon

    Citation: Cardiovascular Diabetology 2017 16:136

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    The original article was published in Cardiovascular Diabetology 2014 13:112

  21. Content type: Correction

    Following publication of the original article [1], author Antonio Ceriello requested that a correction be published in relation to his affiliations. His correct affiliations have been updated in this erratum. Thi...

    Authors: Oliver Schnell, Eberhard Standl, Doina Catrinoiu, Stefano Genovese, Nebojsa Lalic, Jan Skra, Paul Valensi, Dario Rahelic and Antonio Ceriello

    Citation: Cardiovascular Diabetology 2017 16:135

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    The original article was published in Cardiovascular Diabetology 2017 16:35

  22. Content type: Original investigation

    Previous studies have demonstrated that secreted frizzled-related protein 4 (SFRP4) is associated with impaired glucose and triglyceride metabolism in patients with stable coronary artery disease. In the prese...

    Authors: Qingwei Ji, Jianwei Zhang, Yu Du, Enjun Zhu, Zhijian Wang, Bin Que, Huangtai Miao, Shutian Shi, Xiuchuan Qin, Yingxin Zhao, Yujie Zhou, Fangjun Huang and Shaoping Nie

    Citation: Cardiovascular Diabetology 2017 16:133

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  23. Content type: Review

    Pioglitazone targets multiple pathogenic pathways involved in the development of cardiovascular diseases (CVD). The aim of this systematic review and meta-analysis is to assess the effects of pioglitazone trea...

    Authors: Marit de Jong, H. Bart van der Worp, Yolanda van der Graaf, Frank L. J. Visseren and Jan Westerink

    Citation: Cardiovascular Diabetology 2017 16:134

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