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Table 2 Insulin resistance of subjects categorized by body mass index

From: Alanine aminotransferase/aspartate aminotransferase ratio is the best surrogate marker for insulin resistance in non-obese Japanese adults

Body mass index characteristics Total Non-obese Overweight P-value*
  All N = 1,342 <25.0 kg/m2 N = 998 ≥25.0 kg/m2 N = 344  
Fasting blood glucose (mg/dL) 92 (87–99) 91 (86–98) 96 (89–103) <0.001
Immunoreactive insulin (mU/mL) 5.2 (3.4-7.7) 4.5 (3.0-6.6) 8.0 (5.4-11.2) <0.001
HOMA-IR† 1.20 (0.76-1.84) 1.03 (0.67-1.54) 1.93 (1.23-2.81) <0.001
HOMA-IR† <1.6,% 67.5 77.5 38.7  
HOMA-IR† ≥1.6 and <2.5,% 20.0 16.3 30.8 <0.001
HOMA-IR† ≥2.5,% 12.4 6.2 30.5 <0.001
  1. HOMA-IR, homeostasis of minimal assessment of insulin resistance. Data for fasting blood glucose, fasting immunoreactive insulin, and HOMA-IR were skewed, and are presented as median (interquartile range). †HOMA-IR was calculated using the following formula; [fasting blood glucose (FBG) (mg/dL) X fasting Immunoreactive insulin (mU/mL)]/405. Data for fasting blood glucose, Immunoreactive insulin, and HOMA-IR were log-transformed for analysis. *Student’s t test or χ2 test.