Alanine aminotransferase/aspartate aminotransferase ratio is the best surrogate marker for insulin resistance in non-obese Japanese adults

Table 5 Comparison of ALT/AST ratio for predicting of insulin resistance (HOMA-IR ≥2.5) of subjects categorized by body mass index

Characteristics cut-off point	HOMA-IR§
	<2.5	≥2.5	Sensitivity	Specificity	Positive LR	Negative LR	Accuracy
Body mass index <25.0 kg/m²	N = 936	N = 62					%
ALT/AST ratio <0.82	612	22	0.67	0.65	1.91	0.51	65.3
ALT/AST ratio ≥0.82	324	40
Body mass index ≥25.0 kg/m²	N = 239	N = 105
ALT/AST ratio <1.02	158	41	0.66	0.61	1.69	0.56	64.5
ALT/AST ratio ≥1.02	81	64

ISSN: 1475-2840