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Table 5 Comparison of ALT/AST ratio for predicting of insulin resistance (HOMA-IR ≥2.5) of subjects categorized by body mass index

From: Alanine aminotransferase/aspartate aminotransferase ratio is the best surrogate marker for insulin resistance in non-obese Japanese adults

Characteristics cut-off point HOMA-IR§       
  <2.5 ≥2.5 Sensitivity Specificity Positive LR Negative LR Accuracy
Body mass index <25.0 kg/m2 N = 936 N = 62      %
ALT/AST ratio <0.82 612 22 0.67 0.65 1.91 0.51 65.3
ALT/AST ratio ≥0.82 324 40      
Body mass index ≥25.0 kg/m2 N = 239 N = 105      
ALT/AST ratio <1.02 158 41 0.66 0.61 1.69 0.56 64.5
ALT/AST ratio ≥1.02 81 64      
  1. LR, likelihood ratio.