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  1. To assess whether the Multidisciplinary Risk Assessment and Management Program for Patients with Diabetes Mellitus (RAMP-DM) led to improvements in biomedical outcomes, observed cardiovascular events and predi...

    Authors: Fang Fang Jiao, Colman Siu Cheung Fung, Carlos King Ho Wong, Yuk Fai Wan, Daisy Dai, Ruby Kwok and Cindy Lo Kuen Lam
    Citation: Cardiovascular Diabetology 2014 13:127
  2. Fatty acid-binding protein 4 (FABP4) is expressed in both adipocytes and macrophages. Recent studies have shown secretion of FABP4 from adipocytes and association of elevated serum FABP4 level with obesity, in...

    Authors: Takahiro Fuseya, Masato Furuhashi, Satoshi Yuda, Atsuko Muranaka, Mina Kawamukai, Tomohiro Mita, Shutaro Ishimura, Yuki Watanabe, Kyoko Hoshina, Marenao Tanaka, Kohei Ohno, Hiroshi Akasaka, Hirofumi Ohnishi, Hideaki Yoshida, Shigeyuki Saitoh, Kazuaki Shimamoto…
    Citation: Cardiovascular Diabetology 2014 13:126
  3. Abnormal ventricular repolarization is a predictor of cardiovascular mortality. In this study, we tested the hypothesis that glycemic control reverses abnormal ventricular repolarization in patients with type ...

    Authors: Takayuki Miki, Toshiyuki Tobisawa, Tatsuya Sato, Masaya Tanno, Toshiyuki Yano, Hiroshi Akasaka, Atsushi Kuno, Makoto Ogasawara, Hiromichi Murase, Shigeyuki Saitoh and Tetsuji Miura
    Citation: Cardiovascular Diabetology 2014 13:125
  4. Although no receptor has yet been identified, changes in circulating levels of the adipokine designated as Omentin have been demonstrated in obesity and related comorbidities such as cardiovascular disease, in...

    Authors: Marc Lapointe, Paul Poirier, Julie Martin, Marjorie Bastien, Audrey Auclair and Katherine Cianflone
    Citation: Cardiovascular Diabetology 2014 13:124
  5. The interplay between the novel adipokine retinol-binding protein-4 (RBP4) and coronary artery disease (CAD) is still obscure. We investigated the relationship between RBP4 levels and the presence and severity...

    Authors: Vaia Lambadiari, Nikolaos PE Kadoglou, Vassilios Stasinos, Eirini Maratou, Aias Antoniadis, Fotios Kolokathis, John Parissis, Erifili Hatziagelaki, Efstathios K Iliodromitis and George Dimitriadis
    Citation: Cardiovascular Diabetology 2014 13:121
  6. Nestin was reported to directly contribute to cell proliferation and the intermediate filament protein was detected in vascular smooth muscle cells. In experimental type I diabetes, nestin downregulation in th...

    Authors: Kim Tardif, Vanessa Hertig, Camille Dumais, Louis Villeneuve, Louis Perrault, Jean-François Tanguay and Angelino Calderone
    Citation: Cardiovascular Diabetology 2014 13:119
  7. Pathophysiological processes underlying diabetic-related cardiomyopathies are complex. Mitochondria dysfunction is often described as a cause of cardiac impairment but its extent may depend on the type of expe...

    Authors: Camille Marciniak, Xavier Marechal, David Montaigne, Remi Neviere and Steve Lancel
    Citation: Cardiovascular Diabetology 2014 13:118
  8. Evidence from the literature suggests diminished acetylsalicylic acid (ASA) treatment efficacy in type 2 diabetes (DM2). High on-aspirin platelet reactivity (HAPR) in DM2 has been linked to poor glycemic and l...

    Authors: Agnieszka Kaplon-Cieslicka, Marek Postula, Marek Rosiak, Michal Peller, Agnieszka Kondracka, Agnieszka Serafin, Ewa Trzepla, Grzegorz Opolski and Krzysztof J Filipiak
    Citation: Cardiovascular Diabetology 2014 13:112
  9. We have previously shown that EphrinA1/EphA expression profile changes in response to myocardial infarction (MI), exogenous EphrinA1-Fc administration following MI positively influences wound healing, and that...

    Authors: Augustin DuSablon, Susan Kent, Anita Coburn and Jitka Virag
    Citation: Cardiovascular Diabetology 2014 13:114
  10. The aim of this study was to probe cardiac complications, including heart-rate control, in a mouse model of type-2 diabetes. Heart-rate development in diabetic patients is not straight forward: In general, pat...

    Authors: Ewa Soltysinska, Tobias Speerschneider, Sine V Winther and Morten B Thomsen
    Citation: Cardiovascular Diabetology 2014 13:122
  11. Atrial fibrillation (AF), an inflammatory process involving arrhythmia, is associated with severe morbidity and mortality and commonly seen in patients with diabetes mellitus (DM). The effect of metformin, the...

    Authors: Shang-Hung Chang, Lung-Sheng Wu, Meng-Jiun Chiou, Jia-Rou Liu, Kuang-Hui Yu, Chang-Fu Kuo, Ming-Shien Wen, Wei-Jan Chen, Yung-Hsin Yeh and Lai-Chu See
    Citation: Cardiovascular Diabetology 2014 13:123
  12. Growing evidence demonstrates subtle left ventricular myocardial dysfunction in patients with metabolic syndrome (MetS), with central obesity, glucose intolerance and inflammation emerging as important contrib...

    Authors: Juan Serrano-Ferrer, Guillaume Walther, Edward Crendal, Agnès Vinet, Frédéric Dutheil, Geraldine Naughton, Bruno Lesourd, Robert Chapier, Daniel Courteix and Philippe Obert
    Citation: Cardiovascular Diabetology 2014 13:116
  13. We previously demonstrated that older beagles have impaired whole body and myocardial insulin responsiveness (MIR), and that glucagon-like peptide-1 (GLP-1 [7–36] amide) improves MIR in young beagles with dila...

    Authors: Melissa Chen, Franca S Angeli, You-tang Shen and Richard P Shannon
    Citation: Cardiovascular Diabetology 2014 13:115
  14. It has been reported that increased expression of UCP-2 in the vasculature may prevent the development of atherosclerosis in patients with increased production of reactive oxygen species, as in the diabetes, o...

    Authors: Almudena Gómez-Hernández, Liliana Perdomo, Natalia de las Heras, Nuria Beneit, Óscar Escribano, Yolanda F Otero, Carlos Guillén, Sabela Díaz-Castroverde, Beatriz Gozalbo-López, Victoria Cachofeiro, Vicente Lahera and Manuel Benito
    Citation: Cardiovascular Diabetology 2014 13:108
  15. Sepsis is a common disease that continues to increase in incidence in the world. Diseases, such as diabetes mellitus, may make the situation worse. Diabetic patients are at increased risk for common infections...

    Authors: Jian Cai, Shuai Lu, Zheng Yao, Ya-Ping Deng, Ling-Di Zhang, Jia-Wen Yu, Guo-Fei Ren, Fu-Ming Shen and Guo-Jun Jiang
    Citation: Cardiovascular Diabetology 2014 13:106
  16. Alpha glucosidase inhibitor (GI) attenuates postprandial hyperglycemia (PPH) and reduces the risk of cardiovascular events in patients with impaired glucose tolerance or type 2 diabetes. Dipeptidyl peptidase 4...

    Authors: Kazufumi Nakamura, Hiroki Oe, Hajime Kihara, Kenei Shimada, Shota Fukuda, Kyoko Watanabe, Tsutomu Takagi, Kei Yunoki, Toru Miyoshi, Kumiko Hirata, Junichi Yoshikawa and Hiroshi Ito
    Citation: Cardiovascular Diabetology 2014 13:110
  17. Endothelial nitric oxide synthase (eNOS)-uncoupling links obesity-associated insulin resistance and type-II diabetes to the increased incidence of cardiovascular disease. Studies have indicated that increased ...

    Authors: Yi Yu, Angana G Rajapakse, Jean-Pierre Montani, Zhihong Yang and Xiu-Fen Ming
    Citation: Cardiovascular Diabetology 2014 13:113
  18. Although obesity is still considered a risk factor in the development of cardiovascular disorders, recent studies suggested that it may also be associated with reduced morbidity and mortality, the so-called “o...

    Authors: Ruduwaan Salie, Barbara Huisamen and Amanda Lochner
    Citation: Cardiovascular Diabetology 2014 13:109
  19. Circulating endothelial progenitor cells (EPCs) reflect endothelial repair capacity and may be a significant marker for the clinical outcomes of cardiovascular disease. While some high-dose statin treatments m...

    Authors: Liang-Yu Lin, Chin-Chou Huang, Jia-Shiong Chen, Tao-Cheng Wu, Hsin-Bang Leu, Po-Hsun Huang, Ting-Ting Chang, Shing-Jong Lin and Jaw-Wen Chen
    Citation: Cardiovascular Diabetology 2014 13:111
  20. Hyperglycemia has been recognized as a primary factor in endothelial barrier dysfunction and in the development of micro- and macrovascular diseases associated with diabetes, but the underlying biochemical mec...

    Authors: Mehran Haidari, Wei Zhang, James T Willerson and Richard AF Dixon
    Citation: Cardiovascular Diabetology 2014 13:112
  21. Hyperglycemia has been recognized as a primary factor in endothelial barrier dysfunction and in the development of micro- and macrovascular diseases associated with diabetes, but the underlying biochemical mec...

    Authors: Mehran Haidari, Wei Zhang, James T Willerson and Richard AF Dixon
    Citation: Cardiovascular Diabetology 2014 13:105
  22. Women with gestational diabetes history are at increased risk for type 2 diabetes. They face specific challenges for behavioural changes, including childcare responsibilities. The aim of this study is to test ...

    Authors: Anne-Sophie Brazeau, Aaron Leong, Sara J Meltzer, Rani Cruz, Deborah DaCosta, Mary Hendrickson-Nelson, Lawrence Joseph and Kaberi Dasgupta
    Citation: Cardiovascular Diabetology 2014 13:104
  23. Evidence concerning the importance of glucose lowering in the prevention of cardiovascular (CV) outcomes remains controversial. Given the multi-faceted pathogenesis of atherosclerosis in diabetes, it is likely...

    Authors: Bernard Zinman, Silvio E Inzucchi, John M Lachin, Christoph Wanner, Roberto Ferrari, David Fitchett, Erich Bluhmki, Stefan Hantel, Joan Kempthorne-Rawson, Jennifer Newman, Odd Erik Johansen, Hans-Juergen Woerle and Uli C Broedl
    Citation: Cardiovascular Diabetology 2014 13:102
  24. Diabetic patients have a significantly worse prognosis after an acute myocardial infarction (AMI) than their counterparts. Previous studies have shown that the number of circulating endothelial progenitor cell...

    Authors: Natália António, Rosa Fernandes, Ana Soares, Francisco Soares, Ana Lopes, Tiago Carvalheiro, Artur Paiva, Guilherme Mariano Pêgo, Luís A Providência, Lino Gonçalves and Carlos Fontes Ribeiro
    Citation: Cardiovascular Diabetology 2014 13:101
  25. Heart disease is the leading cause of death in diabetic patients, and defective copper metabolism may play important roles in the pathogenesis of diabetic cardiomyopathy (DCM). The present study sought to dete...

    Authors: Shaoping Zhang, Hong Liu, Greeshma V Amarsingh, Carlos C H Cheung, Sebastian Hogl, Umayal Narayanan, Lin Zhang, Selina McHarg, Jingshu Xu, Deming Gong, John Kennedy, Bernard Barry, Yee Soon Choong, Anthony R J Phillips and Garth J S Cooper
    Citation: Cardiovascular Diabetology 2014 13:100
  26. Vascular endothelial dysfunction is involved in macrovascular disease progression in type 2 diabetes mellitus (T2DM). We reported previously that blood glucose fluctuations, as evaluated by continuous glucose ...

    Authors: Keiichi Torimoto, Yosuke Okada, Hiroko Mori and Yoshiya Tanaka
    Citation: Cardiovascular Diabetology 2014 13:99
  27. Caffeic acid phenethyl ester (CAPE) has been shown to protect the heart against ischemia/reperfusion (I/R) injury by various mechanisms including its antioxidant effect. In this study, we evaluated the protect...

    Authors: Yi-Jin Ho, An-Sheng Lee, Wen-Pin Chen, Wei-Lung Chang, Ying-Kang Tsai, Hsi-Lin Chiu, Yueh-Hsiung Kuo and Ming-Jai Su
    Citation: Cardiovascular Diabetology 2014 13:98
  28. Vascular smooth muscle cells (VSMCs) proliferation and migration, which are central in the development of vascular diseases, are regulated by numerous hormones and humoral factors. Activation of the insulin re...

    Authors: Changqing Yu, Zhen Wang, Yu Han, Yukai Liu, Wei Eric Wang, Caiyu Chen, Hongyong Wang, Pedro A Jose and Chunyu Zeng
    Citation: Cardiovascular Diabetology 2014 13:97
  29. The dipeptidyl-peptidase-IV (DPP-4) inhibitors, including sitagliptin, are used for the treatment of type 2 diabetes mellitus (T2DM). Adiponectin, an adipocyte-derived circulating protein, has anti-atheroscler...

    Authors: Toshiyuki Hibuse, Norikazu Maeda, Ken Kishida, Takekazu Kimura, Tomoko Minami, Eriko Takeshita, Ayumu Hirata, Yasuhiko Nakagawa, Susumu Kashine, Akemi Oka, Masumi Hayashi, Hitoshi Nishizawa, Tohru Funahashi and Iichiro Shimomura
    Citation: Cardiovascular Diabetology 2014 13:96
  30. We aimed to assess the safety and tolerability of different doses of canakinumab versus placebo in patients with type 2 diabetes mellitus (T2DM).

    Authors: Campbell Howard, Adele Noe, Andrej Skerjanec, Björn Holzhauer, Margaret Wernsing, Monica Ligueros-Saylan and Tom Thuren
    Citation: Cardiovascular Diabetology 2014 13:94
  31. Metformin (MET) therapy exerts positive effects improving glucose tolerance and preventing the evolution toward diabetes in insulin resistant patients. It has been shown that adding MET to exercise training do...

    Authors: Christian Cadeddu, Silvio Nocco, Lucia Cugusi, Martino Deidda, Alessandro Bina, Orru Fabio, Stefano Bandinu, Efisio Cossu, Marco Giorgio Baroni and Giuseppe Mercuro
    Citation: Cardiovascular Diabetology 2014 13:93
  32. Type 2 diabetes (T2D) is associated with reduction and dysfunction of circulating pro-angiogenic cells (PACs). DPP-4 inhibitors, a class of oral agents for T2D, might possess pleiotropic vasculoprotective acti...

    Authors: Nicol Poncina, Mattia Albiero, Lisa Menegazzo, Roberta Cappellari, Angelo Avogaro and Gian Paolo Fadini
    Citation: Cardiovascular Diabetology 2014 13:92
  33. Angiotensin receptor blockers (ARBs) have been shown to exert various peroxisome proliferator-activated receptor gamma (PPARγ) binding activities and insulin-sensitizing effects. The objective of this study wa...

    Authors: Chia-Hsuin Chang, Yi-Cheng Chang, Li-Chiu Wu, Jou-Wei Lin, Lee-Ming Chuang and Mei-Shu Lai
    Citation: Cardiovascular Diabetology 2014 13:91
  34. The genetic polymorphism concerning the ß3-subunit of platelet integrin receptor glycoprotein IIIa is held responsible for enhanced binding of adhesive proteins resulting in increased thrombogenic potential. W...

    Authors: Bernd Stratmann, Tao Xu, Christa Meisinger, Barbara Menart, Michael Roden, Christian Herder, Harald Grallert, Annette Peters, Wolfgang Koenig, Thomas Illig, Heinz-Erich Wichmann, Rui Wang-Sattler, Wolfgang Rathmann and Diethelm Tschoepe
    Citation: Cardiovascular Diabetology 2014 13:90
  35. Despite advances in the treatment of heart failure, mortality remains high, particularly in individuals with diabetes. Activated transforming growth factor beta (TGF-β) contributes to the pathogenesis of the f...

    Authors: Antoinette Bugyei-Twum, Andrew Advani, Suzanne L Advani, Yuan Zhang, Kerri Thai, Darren J Kelly and Kim A Connelly
    Citation: Cardiovascular Diabetology 2014 13:89
  36. The present study was to investigate the role of calpain in reactive oxygen species (ROS) production in endothelial cells and endothelium-dependent vascular dysfunction under experimental conditions of diabetes.

    Authors: Bainian Chen, Qing Zhao, Rui Ni, Futian Tang, Limei Shan, Inga Cepinskas, Gediminas Cepinskas, Wang Wang, Peter W Schiller and Tianqing Peng
    Citation: Cardiovascular Diabetology 2014 13:88
  37. Intima-media thickness (IMT) of the common carotid artery is a surrogate end point of cardiovascular disease (CVD). Identifying the factors associated with a higher IMT may contribute to the identification of ...

    Authors: Carlos Roberto Moraes de Andrade Junior, Eliete Leão Clemente Silva, Maria de Fátima Bevilaqua da Matta, Marcia Bueno Castier, Maria Luiza Garcia Rosa and Marília de Brito Gomes
    Citation: Cardiovascular Diabetology 2014 13:87
  38. Insulin resistance, as a key mediator of metabolic syndrome, is thought to be associated with pathogenesis of calcific aortic valve disease and altered left ventricular (LV) function and structure. However, in...

    Authors: Hiroto Utsunomiya, Hideya Yamamoto, Eiji Kunita, Takayuki Hidaka and Yasuki Kihara
    Citation: Cardiovascular Diabetology 2014 13:86
  39. Matrix Gla protein (MGP) is an important inhibitor of calcification. The objective of the present study of patients with type 2 diabetes and normal or slightly altered kidney function was to evaluate levels of...

    Authors: Sophie Liabeuf, Bourron Olivier, Cees Vemeer, Elke Theuwissen, Elke Magdeleyns, Carole Elodie Aubert, Michel Brazier, Romuald Mentaverri, Agnes Hartemann and Ziad A Massy
    Citation: Cardiovascular Diabetology 2014 13:85

    The Erratum to this article has been published in Cardiovascular Diabetology 2015 14:9

  40. Various adipokines are reported to be associated with the development of heart failure (HF) through insulin resistance and chronic inflammation. Omentin-1 is a novel adipokine and is associated with incident c...

    Authors: Taro Narumi, Tetsu Watanabe, Shinpei Kadowaki, Daisuke Kinoshita, Miyuki Yokoyama, Yuki Honda, Yoichiro Otaki, Satoshi Nishiyama, Hiroki Takahashi, Takanori Arimoto, Tetsuro Shishido, Takuya Miyamoto and Isao Kubota
    Citation: Cardiovascular Diabetology 2014 13:84
  41. The presence of impaired glucose tolerance (IGT) and metabolic syndrome (MetS) are two risk factors for Type 2 diabetes. The inter-relatedness of these factors among adolescents is unclear.

    Authors: Mark D DeBoer and Matthew J Gurka
    Citation: Cardiovascular Diabetology 2014 13:83
  42. Glycation of high-density lipoprotein (HDL) decreases its ability to induce cyclooxygenase-2 (COX-2) expression and prostacyclin I-2 (PGI-2) release in endothelial cells. Whether lipid content of HDL, especial...

    Authors: Xunliang Tong, Pu Lv, Anna V Mathew, Donghui Liu, Chenguang Niu, Yan Wang, Liang Ji, Jizhao Li, Zhiwei Fu, Bing Pan, Subramaniam Pennathur, Lemin Zheng and Yining Huang
    Citation: Cardiovascular Diabetology 2014 13:82
  43. In the emerging landscape of cardiovascular (CV) outcome trials evaluating the effects of blood glucose lowering drugs in individuals with type 2 diabetes, it is becoming increasingly apparent that since the p...

    Authors: Eberhard Standl, Michael J Theodorakis, Michael Erbach, Oliver Schnell and Jaakko Tuomilehto
    Citation: Cardiovascular Diabetology 2014 13:81
  44. Pharmaceutical interventions for diabetes aim to control glycaemia and to prevent the development of complications, such as cardiovascular diseases. Some anti-hyperglycaemic drugs have been found to have adver...

    Authors: Sefaa Al-aryahi, Danielle Kamato, Robel Getachew, Wenhua Zheng, Simon J Potocnik, Neale Cohen, Daniel Guidone, Narin Osman and Peter J Little
    Citation: Cardiovascular Diabetology 2014 13:80
  45. Diabetes induces numerous electrical, ionic and biochemical defects in the heart. A general feature of diabetic myocardium is its low rate of activity, commonly characterised by prolonged twitch duration. This...

    Authors: June-Chiew Han, Kenneth Tran, Poul MF Nielsen, Andrew J Taberner and Denis S Loiselle
    Citation: Cardiovascular Diabetology 2014 13:79
  46. Rat neonate cardiomyocytes were cultured and treated with AGEs at different concentration. Two classic autophagy markers, microtubule-associated protein 1 light chain 3 (LC3) and Beclin-1, were detected by wes...

    Authors: Xuwei Hou, Zhaohui Hu, Hanying Xu, Jian Xu, Shunrong Zhang, Yigang Zhong, Xiuying He and Ningfu Wang
    Citation: Cardiovascular Diabetology 2014 13:78

Cardiovascular Diabetology is affiliated with Sackler Faculty of Medicine, Tel-Aviv University

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