Chase PJ, Davis PG, Bensimhon DR: The obesity paradox in chronic heart failure: what does it mean?Curr Heart Fail Rep 2014,Epub ahead of print.
Clark AL, Fonarow GC, Horwich TB: Obesity and the obesity paradox in heart failure. Prog Cardiovasc Dis. 2014, 56: 409-410. 10.1016/j.pcad.2013.10.004.
Article
PubMed
Google Scholar
Diercks DB, Roe MT, Mulgund J, Pollack CV, Kirk JD, Gibler WB, Ohman EM, Smith SC, Boden WE, Peterson ED: The obesity paradox in non-ST-segment elevation acute coronary syndromes. Am Heart J. 2006, 152: 140-148. 10.1016/j.ahj.2005.09.024.
Article
PubMed
Google Scholar
Miki T, Itoh T, Sunaga D, Miura T: Effects of diabetes on myocardial infarct size and cardioprotection by preconditioning and postconditioning. Cardiovasc Diabetol. 2012, 11: 67-10.1186/1475-2840-11-67.
Article
PubMed Central
PubMed
Google Scholar
Whittington HJ, Babu GG, Mocanu NM, Yellon DM, Hausenloy DJ: The diabetic heart: too sweet for its own good?. Cardiol Res Pract. 2012, 2012: 845698-doi: 10.1155/2012/845698
PubMed Central
PubMed
Google Scholar
Balakumar P, Singh H, Singh M, Anand-Srivastava MB: The impairment of preconditioning-mediated cardioprotection in pathological conditions. Pharmacol Res. 2009, 60: 18-23. 10.1016/j.phrs.2009.03.002.
Article
PubMed
Google Scholar
Jones SP, Girod WG, Granger DN, Palazzo AJ, Lefer DJ: Reperfusion injury is not affected by blockade of P-selectin in the diabetic mouse heart. Am J Physiol Heart Circ Physiol. 1999, 277: H763-H769.
CAS
Google Scholar
Kersten JR, Toller WG, Gross ER, Pagel PS, Warltier DC: Diabetes abolishes ischemic preconditioning: role of glucose, insulin and osmolality. Am J Physiol. 2000, 278: H1218-H1224.
CAS
Google Scholar
Sidell RJ, Cole MA, Draper NJ, Desrois M, Buckingham RE, Clarke K: Thiazolidinedione treatment normalizes insulin resistance and ischemic injury in the Zucker fatty rat heart. Diabetes. 2002, 51: 1110-1117. 10.2337/diabetes.51.4.1110.
Article
CAS
PubMed
Google Scholar
Marfella R, D’Amico M, Di Filippo C, Piegari E, Nappo F, Esposito K, Berrino L, Rossi F, Giugliano D: Myocardial infarction in diabetic rats: role of hyperglycaemia on infarct size and early expression of hypoxia-inducible factor 1. Diabetologia. 2002, 45: 1172-1181.
Article
CAS
PubMed
Google Scholar
Hadour G, Ferrera R, Sebbag L, Forrat R, Delaye J, de Lorgeril M: Improved myocardial tolerance to ischaemia in the diabetic rabbit. J Mol Cell Cardiol. 1998, 30: 1869-1875. 10.1006/jmcc.1998.0751.
Article
CAS
PubMed
Google Scholar
Ma G, Al-Shabrawey M, Johnson JA, Datar R, Tawfik HE, Guo D, Caldwell RB, Caldwell RW: Protection against myocardial ischemia/reperfusion injury by short-term diabetes: enhancement of VEGF formation, capillary density and activation of cell survival signalling. Naunyn Schmiedebergs Arch Pharmacol. 2006, 373: 415-427. 10.1007/s00210-006-0102-1.
Article
CAS
PubMed
Google Scholar
Kristiansen SB, Lofgren B, Stottrup NB, Khatir D, Nielsen-Kudsk JTE, Nielsen TT, Botker HE, Flyvbjerg A: Ischaemic preconditioning does not protect the heart in obese and lean animal models and type 2 diabetes. Diabetologia. 2004, 47: 1716-1721. 10.1007/s00125-004-1514-4.
Article
CAS
PubMed
Google Scholar
Tsang A, Hausenloy DJ, Mocanu MM, Carr RD, Yellon DM: Preconditioning the diabetic heart: the importance of Akt phosphorylation. Diabetes. 2004, 54: 2360-2364. 10.2337/diabetes.54.8.2360.
Article
Google Scholar
Gurel E, Ustunova S, Kapucu A, Yilmazer N, Eerbeek O, Nederlof R, Hollman MW, Demirci-Tansel C, Zuurbier CJ: Hexokinase cellular trafficking in ischemia-reperfusion and ischaemic preconditioning is altered in type 1 diabetic heart. Mol Biol Rep. 2013, 40: 1753-1760. 10.1007/s11033-013-2495-5.
Article
Google Scholar
Ebel D, Mullenheim J, Frassdorf J, Heinen A, Huhn R, Bohlen R, Ferrari J, Sudkamp H, Preckel B, Schlack W, Thamer V: Effect of acute hyperglycaemia and diabetes mellitus with and without short-term insulin treatment on myocardial ischemic late preconditioning in the rabbit heart in vivo. Pflugers Archiv. 2003, 446: 175-182.
CAS
PubMed
Google Scholar
Matsumoto S, Cho S, Tosaka S, Ureshino H, Maekawa T, Hara T, Sumikawa K: Pharmacological preconditioning in type 2 diabetic rat hearts: the roles of mitochondrial ATP-sensitive potassium channels and the phosphatidylinositol 3-kinase-Akt pathway. Cardiovasc Drugs Therap. 2000, 23: 263-270. 10.1007/s10557-009-6184-5.
Article
Google Scholar
Clark C, Smith W, Lochner A, du Toit EF: The effects of gender and obesity on myocardial tolerance to ischemia. Physiol Res. 2011, 60: 291-301.
CAS
PubMed
Google Scholar
Wensley I, Salaveria K, Bulmer AC, Donner DG, du Toit EF: Myocardial structure, function and ischaemic tolerance in a rodent model of obesity with insulin resistance. Exp Physiol. 2013, 98: 1552-1564. 10.1113/expphysiol.2013.074948.
Article
CAS
PubMed
Google Scholar
Du Toit EF, Smith W, Muller C, Strijdom H, Stouthammer B, Woodiwiss A, Norton GR, Lochner A: Myocardial susceptibility to ischemic-reperfusion injury in a prediabetic model of dietary-induced obesity. Am J Physiol Heart Circ Physiol. 2008, 294: H2336-H2343. 10.1152/ajpheart.00481.2007.
Article
CAS
PubMed
Google Scholar
Nduhirabandi F, du Toit EF, Blackhurst D, Marais D, Lochner A: Chronic melatonin consumption prevents obesity-related metabolic abnormalities and protects the heart against myocardial ischaemia and reperfusion injury in a pre-diabetic model of diet-induced obesity. J Pineal Res. 2011, 50: 171-192.
CAS
PubMed
Google Scholar
Maarman G, Marais E, Lochner A, du Toit EF: Effect of chronic CPT-1 inhibition on myocardial ischaemia-reperfusion injury (I/R) in a model of diet-induced obesity. Cardiovasc Drugs Therap. 2012, 26: 305-316. 10.1007/s10557-012-6377-1.
Article
Google Scholar
Thakker GD, Frangogiannis NG, Zymek PT, Sharma S, Saumya S, Raya JL, Barger PM, Taegtmeyer H, Entman ML, Ballantyne CM: Increased myocardial succeptibility to repetitive ischemia with high fat diet-induced obesity. Obesity. 2008, 16: 2593-2600. 10.1038/oby.2008.414.
Article
PubMed Central
CAS
PubMed
Google Scholar
Bouhidel O, Pons S, Souktani R, Berdeaux A, Ghaleh B: Myocardial ischemic postconditioning against ischemia-reperfusion is impaired in ob/ob mice. Am J Physiol Heart Circ Physiol. 2008, 295: H1580-H1586. 10.1152/ajpheart.00379.2008.
Article
PubMed Central
CAS
PubMed
Google Scholar
Granado M, Fernandez N, Monge L, Figueras JC, Carreno-Tarragona G, Amor S, Garcia-Villalon AL: Effects of coronary ischemia-reperfusion in a rat model of early overnutrition: role of angiotensin receptors. PLoS One. 2013, 8: e54984-10.1371/journal.pone.0054984.
Article
PubMed Central
CAS
PubMed
Google Scholar
Katakam PV, Jordan JE, Snipes JA, Tulbert CD, Miller AW, Busija DW: Myocardial preconditioning against ischemia-reperfusion injury is abolished in Zucker obese rats with insulin resistance. Am J Physiol Regul Integr Comp Physiol. 2007, 292: R920-R926. 10.1152/ajpregu.00520.2006.
Article
CAS
PubMed
Google Scholar
Donner D, Headrick JP, Peart JN, du Toit EF: Obesity improves myocardial ischemic tolerance and RISK signalling in insulin-insensitive rats. Dis Mod Mech. 2013, 6: 457-466. 10.1242/dmm.010959.
Article
CAS
Google Scholar
Balakumar P, Sharma NK: Healing the diabetic heart: does myocardial preconditioning work?. Cell Signal. 2012, 24: 53-59. 10.1016/j.cellsig.2011.09.007.
Article
CAS
PubMed
Google Scholar
Bouchard JF, Lamontagne D: Protection afforded by preconditioning to the diabetic heart against ischaemic injury. Cardiovasc Res. 1998, 37: 82-90. 10.1016/S0008-6363(97)00234-4.
Article
CAS
PubMed
Google Scholar
Tatsumi T, Matoba S, Kobara M, Keira N, Kawahara A, Tsuruyama K, Tanaka T, Katamura M, Nakagawa C, Ohta B, Yamahara Y, Asayama J, Nakagawa M: Energy metabolism after ischaemic preconditioning in streptozotocin-induced diabetic rat hearts. J Am Coll Cardiol. 1998, 31: 707-715. 10.1016/S0735-1097(97)00556-1.
Article
CAS
PubMed
Google Scholar
Liu Y, Thornton JD, Cohen MY, Downey JM, Schaffer SW: Streptozotocin-induced non-insulin dependent diabetes protects the heart from infarction. Circulation. 1993, 88: 1273-1278. 10.1161/01.CIR.88.3.1273.
Article
CAS
PubMed
Google Scholar
Ravingerova T, Stetka R, Pancza D, Ulicna O, Ziegelkoffer A, Styk J: Susceptibility to ischemia-induced arrhythmias and the effect of preconditioning in the diabetic rat heart. Physiol Res. 2000, 49: 607-616.
CAS
PubMed
Google Scholar
Vinokur V, Berenshtein E, Bulvik B, Grinberg L, Eliashar R, Chevion M: The bitter fate of the sweet heart: impairment of iron homeostasis in diabetic heart leads to failure in myocardial protection by preconditioning. PLos One. 2013, 8: e62948-10.1371/journal.pone.0062948.
Article
PubMed Central
CAS
PubMed
Google Scholar
Hausenloy D, Tsang A, Mocanu MM, Yellon DM: Ischemic preconditioning protects by activating prosurvival kinses at reperfusion. Am J Physiol Heart Circ Physiol. 2005, 288: H971-H976. 10.1152/ajpheart.00374.2004.
Article
CAS
PubMed
Google Scholar
Hausenloy DJ, Yellon DM: Reperfusion injury salvage kinase signalling: taking a RISK for cardioprotection. Heart Fail Rev. 2007, 12: 217-234. 10.1007/s10741-007-9026-1.
Article
CAS
PubMed
Google Scholar
Huisamen B: Protein kinase B in the diabetic heart. Mol Cell Biochem. 2003, 249: 31-38. 10.1023/A:1024749614222.
Article
CAS
PubMed
Google Scholar
Xu G, Takashi E, Udo M, Ishiwata T, Naito S: Contradictory effects of short- and long-term hyperglycemias on ischemic injury of myocardium via intracellular signalling pathway. Exp Mol Pathol. 2004, 76: 57-65. 10.1016/j.yexmp.2003.08.003.
Article
CAS
PubMed
Google Scholar
Strniskova M, Barancik M, Neckar J, Ravingerova T: Mitogen-activated protein kinases in the acute diabetic myocardium. Mol Cell Biochem. 2003, 249: 59-65. 10.1023/A:1024774303744.
Article
CAS
PubMed
Google Scholar
Pickavance LC, Tadayyon M, Widdowson PS, Buckingham RE, Wilding JPH: Therapeutic index for rosiglitazone in dietary obese rats: separation of efficacy and haemodilution. Brit J Pharmacol. 1999, 128: 1570-1576. 10.1038/sj.bjp.0702932.
Article
CAS
Google Scholar
Lochner A, Genade S, Tromp E, Podzuweit T, Moolman JA: Ischaemic preconditioning and the beta-adrenergic signal transduction pathway. Circulation. 1999, 100: 958-966. 10.1161/01.CIR.100.9.958.
Article
CAS
PubMed
Google Scholar
Lochner A, Genade S, Moolman JA: Ischaemic preconditioning: infarct size is a more reliable endpoint than functional recovery. Basic Res Cardiol. 2003, 98: 337-346. 10.1007/s00395-003-0427-6.
Article
CAS
PubMed
Google Scholar
Salie R, Moolman JA, Lochner A: The mechanism of beta-adrenergic preconditioning: roles for adenosine and ROS during triggering and mediation. Basic Res Cardiol. 2012, 107: 281-303. 10.1007/s00395-012-0281-5.
Article
PubMed
Google Scholar
Bradford MM: A rapid and sensitive method for the quantification of microgram quantities protein utilizing the principle of protein-dye binding. Anal Biochem. 1976, 72: 248-254. 10.1016/0003-2697(76)90527-3.
Article
CAS
PubMed
Google Scholar
Du Toit EF, Nabben M, Lochner A: A potential role for angiotensin II in obesity–induced cardiac hypertrophy and ischaemic /reperfusion injury. Basic Res Cardiol. 2005, 100: 346-354. 10.1007/s00395-005-0528-5.
Article
CAS
PubMed
Google Scholar
Wilson CR, Tran MK, Salazar KL, Young ME, Taegtmeyer H: Western diet but not high fat diet, causes derangements of fatty acid metabolism and contractile dysfunction in the heart of Wistar rats. Biochem J. 2007, 406: 457-467. 10.1042/BJ20070392.
Article
PubMed Central
CAS
PubMed
Google Scholar
Harmancey R, Vasquez HG, Guthrie PH, Taegtmeyer H: Decreased long-chain fatty acid oxidation impairs postischemic recovery of the insulin-resistant rat heart. FASEB Journal. 2013, 27: 3966-3978. 10.1096/fj.13-234914.
Article
PubMed Central
CAS
PubMed
Google Scholar
Mazumder PK, O’Neill BT, Roberts MW, Buchanan J, Yun UJ, Cooksey RC, Boudina S, Abel ED: Impaired cardiac efficiency and increased fatty acid oxidation in insulin-resistant ob/ob mouse hearts. Diabetes. 2004, 53: 2366-2374. 10.2337/diabetes.53.9.2366.
Article
CAS
PubMed
Google Scholar
Buchanan J, Mazumder PK, Ping H, Chakrabarti G, Roberts MW, Yun UJ, Cooksey RC, Litwin SE, Abel ED: Reduced cardiac efficiency and altered substrate metabolism precedes the onset of hyperglycemia and contractile dysfunction in two mouse models of insulin resistance and obesity. Endocrinology. 2005, 146: 5341-5349. 10.1210/en.2005-0938.
Article
CAS
PubMed
Google Scholar
Van der Mieren G, Nevelsteen I, Vanderper A, Oosterlinck W, Flameng W, Herigers P: Angiotensin-converting enzyme inhibition and food restriction in diabetic mice do not correct the increased sensitivity for ischemia-reperfusion injury. Cardiovasc Diabetol. 2012, 11: 89-10.1186/1475-2840-11-89. doi: 10.1186/1475-2840-11-89
Article
PubMed Central
CAS
PubMed
Google Scholar
Van der Mieren G, Nevelsteen I, Vanderper A, Oosterlonck W, Flameng W, Herigers P: Angiotensin-converting enzyme inhibition and food restriction restore delayed preconditioning in diabetic mice. Cardiovasc Diabetol. 2013, 12: 36-10.1186/1475-2840-12-36. http://www.cardiab.com/content/12/1/36, [http://www.cardiab.com/content/12/1/36]
Article
PubMed Central
CAS
PubMed
Google Scholar