NCD Risk Factor Collaboration (NCD-RISC). Worldwide trends in diabetes since 1980: a pooled analysis of 751 population-based studies with 4.4 million participants. Lancet. 2016;387(10027):1513–30.
Article
Google Scholar
Donadello K, Piagnerelli M, Reggiori G, Gottin L, Scolletta S, Occhipinti G, Zouaoui Boudjeltia K, Vincent JL. Reduced red blood cell deformability over time is associated with a poor outcome in septic patients. Microvasc Res. 2015;101:8–14.
Article
PubMed
Google Scholar
Karim F, Akter QS, Jahan S, Khanom A, Haque S, Yeasmin T, Siddika T, Sinha S. Coagulation Impairment in type 2 diabetes mellitus. J. Bangladesh Soc Physiol. 2015;10(1):26–9.
Article
Google Scholar
Nguyen-Chi M, Laplace-Builhe B, Travnickova J, Luz-Crawford P, Tejedor G, Phan QT, Duroux-Richard I, Levraud JP, Kissa K, Lutfalla G, et al. Identification of polarized macrophage subsets in zebrafish. eLife. 2015;4:e07288.
Article
PubMed
PubMed Central
CAS
Google Scholar
Colwell JA, Nesto RW. The platelet in diabetes: focus on prevention of ischemic events. Diabetes Care. 2003;26(7):2181–8.
Article
PubMed
Google Scholar
Pretorius E, Kell DB. Diagnostic morphology: biophysical indicators for iron-driven inflammatory diseases. Integr Biol. 2014;6(5):486–510.
Article
CAS
Google Scholar
Kell DB, Pretorius E. The simultaneous occurrence of both hypercoagulability and hypofibrinolysis in blood and serum during systemic inflammation, and the roles of iron and fibrin(ogen). Integr Biol. 2015;7:24–52.
Article
CAS
Google Scholar
Goldberg RB. Cytokine and cytokine-like inflammation markers, endothelial dysfunction, and imbalanced coagulation in development of diabetes and its complications. J Clin Endocrinol Metab. 2009;94(9):3171–82.
Article
CAS
PubMed
Google Scholar
Stolar MW, Chilton RJ. Type 2 diabetes, cardiovascular risk, and the link to insulin resistance. Clin Ther. 2003;25(Suppl B):B4–31.
Article
CAS
PubMed
Google Scholar
Wellen KE, Hotamisligil GS. Inflammation, stress, and diabetes. J Clin Investig. 2005;115(5):1111–9.
Article
CAS
PubMed
PubMed Central
Google Scholar
Glatz JF, Dyck JR, Des Rosiers C. Cardiac adaptations to obesity, diabetes and insulin resistance. New York: Elsevier; 2018.
Book
Google Scholar
Bril F, Cusi K. Basic concepts in insulin resistance and diabetes treatment. Dermatology and diabetes. Berlin: Springer; 2018. p. 19–35.
Chapter
Google Scholar
Pretorius E, Bester J, Vermeulen N, Alummoottil S, Soma P, Buys AV, Kell DB. Poorly controlled type 2 diabetes is accompanied by significant morphological and ultrastructural changes in both erythrocytes and in thrombin-generated fibrin: implications for diagnostics. Cardiovasc Diabetol. 2015;14:30.
Article
PubMed
PubMed Central
CAS
Google Scholar
Domingueti CP, Dusse LMSA, das Graças Carvalho M, de Sousa LP, Gomes KB, Fernandes AP. Diabetes mellitus: the linkage between oxidative stress, inflammation, hypercoagulability and vascular complications. J Diab Compl. 2016;30(4):738–45.
Article
Google Scholar
Mutie PM, Giordano GN, Franks PW. Lifestyle precision medicine: the next generation in type 2 diabetes prevention? BMC Med. 2017;15(1):171.
Article
PubMed
PubMed Central
CAS
Google Scholar
Esser N, Legrand-Poels S, Piette J, Scheen AJ, Paquot N. Inflammation as a link between obesity, metabolic syndrome and type 2 diabetes. Diabetes Res Clin Pract. 2014;105(2):141–50.
Article
CAS
PubMed
Google Scholar
van der Leeuw J, Beulens JW, van Dieren S, Schalkwijk CG, Glatz JF, Hofker MH, Verschuren WM, Boer JM, van der Graaf Y, Visseren FL, et al. Novel biomarkers to improve the prediction of cardiovascular event risk in type 2 diabetes mellitus. J Am Heart Assoc. 2016;5:6.
Google Scholar
Hotamisligil GS, Arner P, Caro JF, Atkinson RL, Spiegelman BM. Increased adipose tissue expression of tumor necrosis factor-alpha in human obesity and insulin resistance. J Clin Investig. 1995;95(5):2409–15.
Article
CAS
PubMed
PubMed Central
Google Scholar
Keane KN, Calton EK, Carlessi R, Hart PH, Newsholme P. The bioenergetics of inflammation: insights into obesity and type 2 diabetes. Eur J Clin Nutr. 2017;71(7):904–12.
Article
CAS
PubMed
Google Scholar
Franks PW, Poveda A. Lifestyle and precision diabetes medicine: will genomics help optimise the prediction, prevention and treatment of type 2 diabetes through lifestyle therapy? Diabetologia. 2017;60(5):784–92.
Article
PubMed
PubMed Central
Google Scholar
McCarthy MI. Painting a new picture of personalised medicine for diabetes. Diabetologia. 2017;60(5):793–9.
Article
PubMed
PubMed Central
Google Scholar
De Buck M, Gouwy M, Wang JM, Van Snick J, Proost P, Struyf S, Van Damme J. The cytokine-serum amyloid A-chemokine network. Cytokine Growth Factor Rev. 2016;30:55–69.
Article
PubMed
CAS
Google Scholar
Bray C, Bell LN, Liang H, Haykal R, Kaiksow F, Mazza JJ, Yale SH. Erythrocyte sedimentation rate and C-reactive protein measurements and their relevance in clinical medicine. Off Publ State Med Soc Wisconsin. 2016;115(6):317–21.
Google Scholar
Pepys MB, Hirschfield GM. C-reactive protein: a critical update. J Clin Investig. 2003;111(12):1805–12.
Article
CAS
PubMed
PubMed Central
Google Scholar
Pradhan S, Ghimire A, Bhattarai B, Khanal B, Pokharel K, Lamsal M, Koirala S. The role of C-reactive protein as a diagnostic predictor of sepsis in a multidisciplinary Intensive Care Unit of a tertiary care center in Nepal. Indian J Crit Care Med. 2016;20(7):417–20.
Article
CAS
PubMed
PubMed Central
Google Scholar
Katz FE, Parkar M, Stanley K, Murray LJ, Clark EA, Greaves MF. Chromosome mapping of cell membrane antigens expressed on activated B cells. Eur J Immunol. 1985;15(1):103–6.
Article
CAS
PubMed
Google Scholar
Hubbard AK, Rothlein R. Intercellular adhesion molecule-1 (ICAM-1) expression and cell signaling cascades. Free Radical Biol Med. 2000;28(9):1379–86.
Article
CAS
Google Scholar
Fingar VH, Taber SW, Buschemeyer WC, ten Tije A, Cerrito PB, Tseng M, Guo H, Johnston MN, Wieman TJ. Constitutive and stimulated expression of ICAM-1 protein on pulmonary endothelial cells in vivo. Microvasc Res. 1997;54(2):135–44.
Article
CAS
PubMed
Google Scholar
Javaid K, Rahman A, Anwar KN, Frey RS, Minshall RD, Malik AB. Tumor necrosis factor-alpha induces early-onset endothelial adhesivity by protein kinase Czeta-dependent activation of intercellular adhesion molecule-1. Circ Res. 2003;92(10):1089–97.
Article
CAS
PubMed
Google Scholar
Myers CL, Wertheimer SJ, Schembri-King J, Parks T, Wallace RW. Induction of ICAM-1 by TNF-alpha, IL-1 beta, and LPS in human endothelial cells after downregulation of PKC. Am J Physiol. 1992;263(4 Pt 1):C767–72.
Article
CAS
PubMed
Google Scholar
Chiu JJ, Wung BS, Shyy JY, Hsieh HJ, Wang DL. Reactive oxygen species are involved in shear stress-induced intercellular adhesion molecule-1 expression in endothelial cells. Arterioscler Thromb Vasc Biol. 1997;17(12):3570–7.
Article
CAS
PubMed
Google Scholar
Karimi Z, Kahe F, Jamil A, Marszalek J, Ghanbari A, Afarideh M, Khajeh E, Noshad S, Esteghamati A, Chi G. Intercellular adhesion molecule-1 in diabetic patients with and without microalbuminuria. Diabetes Metab Syndr. 2018;12(3):365–8.
Article
PubMed
Google Scholar
Price DT, Loscalzo J. Cellular adhesion molecules and atherogenesis. Am J Med. 1999;107(1):85–97.
Article
CAS
PubMed
Google Scholar
Osborn L, Hession C, Tizard R, Vassallo C, Luhowskyj S, Chi-Rosso G, Lobb R. Direct expression cloning of vascular cell adhesion molecule 1, a cytokine-induced endothelial protein that binds to lymphocytes. Cell. 1989;59(6):1203–11.
Article
CAS
PubMed
Google Scholar
Rice GE, Bevilacqua MP. An inducible endothelial cell surface glycoprotein mediates melanoma adhesion. Science (New York, NY). 1989;246(4935):1303–6.
Article
CAS
Google Scholar
Cook-Mills JM, Marchese ME, Abdala-Valencia H. Vascular cell adhesion molecule-1 expression and signaling during disease: regulation by reactive oxygen species and antioxidants. Antioxid Redox Signal. 2011;15(6):1607–38.
Article
CAS
PubMed
PubMed Central
Google Scholar
Wittchen ES. Endothelial signaling in paracellular and transcellular leukocyte transmigration. Front Biosci (Landmark edition). 2009;14:2522–45.
Article
CAS
Google Scholar
Liu JJ, Yeoh LY, Sum CF, Tavintharan S, Ng XW, Liu S, Lee SB, Tang WE, Lim SC. Vascular cell adhesion molecule-1, but not intercellular adhesion molecule-1, is associated with diabetic kidney disease in Asians with type 2 diabetes. J Diabetes Complications. 2015;29(5):707–12.
Article
CAS
PubMed
Google Scholar
Braatvedt GD, Gamble G, Ockelford P, Bagg W, Ferri C, Desideri G. The influences of obesity and glycemic control on endothelial activation in patients with type 2 diabetes. J Clin Endocrinol Metab. 2001;86(11):5491–7.
Article
PubMed
Google Scholar
De Vriese AS, Verbeuren TJ, Van de Voorde J, Lameire NH, Vanhoutte PM. Endothelial dysfunction in diabetes. Br J Pharmacol. 2000;130(5):963–74.
Article
PubMed
PubMed Central
Google Scholar
Devaraj S, Jialal I. Low-density lipoprotein postsecretory modification, monocyte function, and circulating adhesion molecules in type 2 diabetic patients with and without macrovascular complications: the effect of alpha-tocopherol supplementation. Circulation. 2000;102(2):191–6.
Article
CAS
PubMed
Google Scholar
Wang X, Bao W, Liu J, Ouyang YY, Wang D, Rong S, Xiao X, Shan ZL, Zhang Y, Yao P, et al. Inflammatory markers and risk of type 2 diabetes: a systematic review and meta-analysis. Diabetes Care. 2013;36(1):166–75.
Article
CAS
PubMed
Google Scholar
Eklund KK, Niemi K, Kovanen PT. Immune functions of serum amyloid A. Crit Rev Immunol. 2012;32(4):335–48.
Article
CAS
PubMed
Google Scholar
Thompson JC, Jayne C, Thompson J, Wilson PG, Yoder MH, Webb N, Tannock LR. A brief elevation of serum amyloid A is sufficient to increase atherosclerosis. J Lipid Res. 2015;56(2):286–93.
Article
CAS
PubMed
PubMed Central
Google Scholar
Li J, Tan M, Xiang Q, Zhou Z, Yan H. Thrombin-activated platelet-derived exosomes regulate endothelial cell expression of ICAM-1 via microRNA-223 during the thrombosis-inflammation response. Thromb Res. 2017;154:96–105.
Article
CAS
PubMed
Google Scholar
Herter JM, Rossaint J, Zarbock A. Platelets in inflammation and immunity. J Thromb Haemost. 2014;12(11):1764–75.
Article
CAS
PubMed
Google Scholar
Olumuyiwa-Akeredolu OO, Page MJ, Soma P, Pretorius E. Platelets: emerging facilitators of cellular crosstalk in rheumatoid arthritis. Nat Rev Rheumatol. 2019;15:237–48.
PubMed
Google Scholar
Bombeli T, Schwartz BR, Harlan JM. Adhesion of activated platelets to endothelial cells: evidence for a GPIIbIIIa-dependent bridging mechanism and novel roles for endothelial intercellular adhesion molecule 1 (ICAM-1), alphavbeta3 integrin, and GPIbalpha. J Exp Med. 1998;187(3):329–39.
Article
CAS
PubMed
PubMed Central
Google Scholar
Meza D, Shanmugavelayudam SK, Mendoza A, Sanchez C, Rubenstein DA, Yin W. Platelets modulate endothelial cell response to dynamic shear stress through PECAM-1. Thromb Res. 2017;150:44–50.
Article
CAS
PubMed
Google Scholar
Shi J, Zhu N, Wang J, Wang Y, Geng Z, Gao S, Li Z. Expression of platelet collagen receptor glycoprotein VI in coronary heart disease: interaction between platelets and endothelial cells. Clinical laboratory. 2016;62(7):1279–86.
CAS
PubMed
Google Scholar
Ye RD, Sun L. Emerging functions of serum amyloid A in inflammation. J Leukoc Biol. 2015;98(6):923–9.
Article
CAS
PubMed
PubMed Central
Google Scholar
de Beer MC, Yuan T, Kindy MS, Asztalos BF, Roheim PS, de Beer FC. Characterization of constitutive human serum amyloid A protein (SAA4) as an apolipoprotein. J Lipid Res. 1995;36(3):526–34.
PubMed
Google Scholar
Cabana VG, Reardon CA, Wei B, Lukens JR, Getz GS. SAA-only HDL formed during the acute phase response in apoA-I+/+ and apoA-I−/− mice. J Lipid Res. 1999;40(6):1090–103.
CAS
PubMed
Google Scholar
Kisilevsky R, Manley PN. Acute-phase serum amyloid A: perspectives on its physiological and pathological roles. Amyloid. 2012;19(1):5–14.
Article
CAS
PubMed
Google Scholar
Hua S, Song C, Geczy CL, Freedman SB, Witting PK. A role for acute-phase serum amyloid A and high-density lipoprotein in oxidative stress, endothelial dysfunction and atherosclerosis. Redox Rep. 2009;14(5):187–96.
Article
CAS
PubMed
Google Scholar
Jayaraman S, Haupt C, Gursky O. Thermal transitions in serum amyloid A in solution and on the lipid: implications for structure and stability of acute-phase HDL. J Lipid Res. 2015;56(8):1531–42.
Article
CAS
PubMed
PubMed Central
Google Scholar
Zewinger S, Drechsler C, Kleber ME, Dressel A, Riffel J, Triem S, Lehmann M, Kopecky C, Saemann MD, Lepper PM, et al. Serum amyloid A: high-density lipoproteins interaction and cardiovascular risk. Eur Heart J. 2015;36(43):3007–16.
CAS
PubMed
Google Scholar
Malle E, De Beer FC. Human serum amyloid A (SAA) protein: a prominent acute-phase reactant for clinical practice. Eur J Clin Invest. 1996;26(6):427–35.
Article
CAS
PubMed
Google Scholar
Bozinovski S, Hutchinson A, Thompson M, Macgregor L, Black J, Giannakis E, Karlsson AS, Silvestrini R, Smallwood D, Vlahos R, et al. Serum amyloid a is a biomarker of acute exacerbations of chronic obstructive pulmonary disease. Am J Respir Crit Care Med. 2008;177(3):269–78.
Article
CAS
PubMed
Google Scholar
Cicarelli DD, Vieira JE, Benseñor FE. Comparison of C-reactive protein and serum amyloid a protein in septic shock patients. Mediators Inflamm. 2008;2008:631414.
Article
PubMed
PubMed Central
CAS
Google Scholar
Delanghe JR, Langlois MR, De Bacquer D, Mak R, Capel P, Van Renterghem L, De Backer G. Discriminative value of serum amyloid A and other acute-phase proteins for coronary heart disease. Atherosclerosis. 2002;160(2):471–6.
Article
CAS
PubMed
Google Scholar
Johnson BD, Kip KE, Marroquin OC, Ridker PM, Kelsey SF, Shaw LJ, Pepine CJ, Sharaf B, Bairey Merz CN, Sopko G, et al. Serum amyloid A as a predictor of coronary artery disease and cardiovascular outcome in women: the National Heart, Lung, and Blood Institute-Sponsored Women’s Ischemia Syndrome Evaluation (WISE). Circulation. 2004;109(6):726–32.
Article
CAS
PubMed
Google Scholar
Getz GS, Krishack PA, Reardon CA. Serum amyloid A and atherosclerosis. Curr Opin Lipidol. 2016;27(5):531–5.
Article
CAS
PubMed
Google Scholar
Slater A, Perrella G, Onselaer MB, Martin EM, Gauer JS, Xu RG, Heemskerk JW, Ariens RAS, Watson SP. Does fibrin(ogen) bind to monomeric or dimeric GPVI, or not at all? Platelets. 2018;30:28.
Google Scholar
Alshehri OM, Hughes CE, Montague S, Watson SK, Frampton J, Bender M, Watson SP. Fibrin activates GPVI in human and mouse platelets. Blood. 2015;126(13):1601–8.
Article
CAS
PubMed
PubMed Central
Google Scholar
Lee SJ, Hong JM, Lee SE, Kang DR, Ovbiagele B, Demchuk AM, Lee JS. Association of fibrinogen level with early neurological deterioration among acute ischemic stroke patients with diabetes. BMC Neurol. 2017;17(1):101.
Article
PubMed
PubMed Central
CAS
Google Scholar
Mammadova-Bach E, Ollivier V, Loyau S, Schaff M, Dumont B, Favier R, Freyburger G, Latger-Cannard V, Nieswandt B, Gachet C, et al. Platelet glycoprotein VI binds to polymerized fibrin and promotes thrombin generation. Blood. 2015;126(5):683–91.
Article
CAS
PubMed
Google Scholar
Estevez B, Du X. New concepts and mechanisms of platelet activation signaling. Physiology (Bethesda, Md). 2017;32(2):162–77.
CAS
Google Scholar
Lee MY, Verni CC, Herbig BA, Diamond SL. Soluble fibrin causes an acquired platelet glycoprotein VI signaling defect: implications for coagulopathy. J Thromb Haemost. 2017;15(12):2396–407.
Article
CAS
PubMed
PubMed Central
Google Scholar
Page MJ, Thomson GJA, Nunes JM, Engelbrecht AM, Nell TA, de Villiers WJS, de Beer MC, Engelbrecht L, Kell DB, Pretorius E. Serum amyloid A binds to fibrin(ogen), promoting fibrin amyloid formation. Sci Rep. 2019;9(1):3102.
Article
PubMed
PubMed Central
CAS
Google Scholar
Pretorius E, Page MJ, Engelbrecht L, Ellis GC, Kell DB. Substantial fibrin amyloidogenesis in type 2 diabetes assessed using amyloid-selective fluorescent stains. Cardiovasc Diabetol. 2017;16(1):141.
Article
PubMed
PubMed Central
CAS
Google Scholar
Pretorius E, Mbotwe S, Kell DB. Lipopolysaccharide-binding protein (LBP) reverses the amyloid state of fibrin seen in plasma of type 2 diabetics with cardiovascular co-morbidities. Sci Rep. 2017;7(1):9680.
Article
PubMed
PubMed Central
Google Scholar
Pretorius E, Bester J. Viscoelasticity as a measurement of clot structure in poorly controlled type 2 diabetes patients: towards a precision and personalized medicine approach. Oncotarget. 2016;7(32):50895–907.
Article
PubMed
PubMed Central
Google Scholar
Huo Y, Ley K. Adhesion molecules and atherogenesis. Acta Physiol Scand. 2001;173(1):35–43.
Article
CAS
PubMed
Google Scholar
de Waal GM, Engelbrecht L, Davis T, de Villiers WJS, Kell DB, Pretorius E. Correlative light-electron microscopy detects lipopolysaccharide and its association with fibrin fibres in Parkinson’s Disease, Alzheimer’s Disease and Type 2 Diabetes Mellitus. Sci Rep. 2018;8(1):16798.
Article
PubMed
PubMed Central
CAS
Google Scholar
Bester J, Matshailwe C, Pretorius E. Simultaneous presence of hypercoagulation and increased clot lysis time due to IL-1beta, IL-6 and IL-8. Cytokine. 2018;110:237–42.
Article
CAS
PubMed
Google Scholar
Bester J, Pretorius E. Effects of IL-1beta, IL-6 and IL-8 on erythrocytes, platelets and clot viscoelasticity. Sci Rep. 2016;6:32188.
Article
CAS
PubMed
PubMed Central
Google Scholar
Pretorius L, Thomson GJA, Adams RCM, Nell TA, Laubscher WA, Pretorius E. Platelet activity and hypercoagulation in type 2 diabetes. Cardiovasc Diabetol. 2018;17(1):141.
Article
PubMed
PubMed Central
Google Scholar
Welsh P, Murray HM, Ford I, Trompet S, de Craen AJ, Jukema JW, Stott DJ, McInnes IB, Packard CJ, Westendorp RG, et al. Circulating interleukin-10 and risk of cardiovascular events: a prospective study in the elderly at risk. Arterioscler Thromb Vasc Biol. 2011;31(10):2338–44.
Article
CAS
PubMed
Google Scholar
Botha-Scheepers S, Watt I, Slagboom E, de Craen AJ, Meulenbelt I, Rosendaal FR, Breedveld FC, Huizinga TW, Kloppenburg M. Innate production of tumour necrosis factor alpha and interleukin 10 is associated with radiological progression of knee osteoarthritis. Ann Rheum Dis. 2008;67(8):1165–9.
Article
CAS
PubMed
Google Scholar
Moore KW, de Waal Malefyt R, Coffman RL, O'Garra A. Interleukin-10 and the interleukin-10 receptor. Annu Rev Immunol. 2001;19:683–765.
Article
CAS
PubMed
Google Scholar
Xie F, Chan JC, Ma RC. Precision medicine in diabetes prevention, classification and management. J Diabetes Invest. 2018;9(5):998–1015.
Article
Google Scholar
de Vries JK, Levin A, Loud F, Adler A, Mayer G, Pena MJ. Implementing personalized medicine in diabetic kidney disease: stakeholders’ perspectives. Diabetes Obes Metab. 2018;20(Suppl 3):24–9.
Article
PubMed
PubMed Central
Google Scholar