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Table 3 Sample demographics of study population, healthy and diabetic, and medication profile of diabetic volunteers

From: Inflammatory cytokines in type 2 diabetes mellitus as facilitators of hypercoagulation and abnormal clot formation

(a) Sample demographics of 20-Plex cytokine analysis, thromboelastography and lipogram analysis, healthy (n = 23) and diabetic (n = 25) volunteers

 

Healthy individuals (n = 23)

Diabetic individuals (n = 25)

P-values

Gender

Male (n = 14)

Male (n = 13)

 

Female (n = 9)

Female (n = 12)

 

Age (years)

55.30 ± 3.59

59.75 ± 3.07

 

HbA1c (%)

5.43 ± 0.10

9.05 ± 0.58

< 0.0001

Diabetic medication

 Hyperglycaemia medication

–

n = 17 (68.00%)

 

 Hypertension medication

–

n = 16 (64.00%)

 

 Hyperlipidaemia medication

–

n = 9 (36.00%)

 

 Anticoagulant medication

–

n = 12 (48.00%)

 

(b) Sample demographics of V-Plex vascular injury analysis, healthy (n = 36) and diabetic (n = 38) volunteers

 

Healthy individuals (n = 36)

Diabetic individuals (n = 38)

P-values

Gender

Male (n = 16)

Male (n = 19)

 

Female (n = 20)

Female (n = 19)

 

Age (years)

58.11 ± 10.98

64.58 ± 12.42

 

HbA1c (%)

5.25 ± 0.09

8.96 ± 0.46

< 0.0001

Diabetic medication

 Hyperglycaemia medication

–

n = 30 (83.33%)

 

 Hypertension medication

–

n = 25 (69.44%)

 

 Hyperlipidaemia medication

–

n = 18 (50.00%)

 

 Anticoagulant medication

–

n = 19 (52.78%)

 
  1. Data expressed as mean ± SEM. No significant correlation was observed between age and HbA1c between the healthy and diabetic samples (Spearman-test) of both 20-Plex (and V-Plex analysis. Medications prescribed and used by diabetic volunteers were recorded, where n is the number of diabetic individuals on specific medication. Medication prescribed for hyperglycaemia included; Diamacron, Diaglucide Metformin, Diaphage, Pioglitazone, Galvus and insulin injections (Optisulin, Actraphane, Protaphane, Novomix, Apidra, Lantus, Actrapid, LEVEMIR®, Humulin). Medication prescribed for blood pressure regulation included; Zartan, Ridaq, Coversyl, Amlodipine, Pritor, LASIX® Retard, Ciplavasc, Adco-Zetomax, Indapamide, Carvedilol, Carloc, Amloc Tareg, Adalat, Ciplazar, Spiractin, Irbesartan, Verahexal SR. Medication prescribed for cholesterol regulation included; Simvas, Adco Simvastatintatin, Atorvastatin, Vusor, Aspavor, Bezafibrate.; anticoagulant medication consisted of; Xarelto, Clexane, Aspirin, Heparin, Clopidogrel, Clexane, Ecotrin, novel oral anticoagulants