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Table 1 Thromboelastography clot parameters for WB and PPP

From: Inflammatory cytokines in type 2 diabetes mellitus as facilitators of hypercoagulation and abnormal clot formation

Parameters

Explanation

R value: reaction time; measured in minutes

Time of latency from start of test to initial fibrin formation (amplitude of 2 mm); i.e. initiation time

K value: kinetics; measured in minutes

Time taken to achieve a certain level of clot strength (amplitude of 20 mm); i.e. amplification

Angle (Α/Alpha): slope between the traces represented by R and K; measured in degrees

The angle measures the speed at which fibrin build up and cross linking takes place, hence assesses the rate of clot formation; i.e. thrombin burst

Maximal amplitude (MA): measured in mm

Maximum strength/stiffness of clot. Reflects the ultimate strength of the fibrin clot, i.e. overall stability of the clot

Maximum rate of thrombus generation (MRTG): measured in Dyn cm−2 s−1

The maximum velocity of clot growth observed or maximum rate of thrombus generation using G, where G is the elastic modulus strength of the thrombus in dynes per cm−2

Time to maximum rate of thrombus generation (TMRTG): measured in minutes

The time interval observed before the maximum speed of the clot growth

Total thrombus generation (TTG): measured in Dyn cm−2

The clot strength: the amount of total resistance (to movement of the cup and pin) generated during clot formation. This is the total area under the velocity curve during clot growth, representing the amount of clot strength generated during clot growth

Coagulation index (CI)

Overall assessment of coagulability