Wren C, Birrell G, Hawthorne G: Cardiovascular malformations in infants of diabetic mothers. Heart. 2003, 89 (10): 1217-1220. 10.1136/heart.89.10.1217.
Article
PubMed Central
CAS
PubMed
Google Scholar
Enciso JM, Gratzinger D, Camenisch TD, Canosa S, Pinter E, Madri JA: Elevated glucose inhibits VEGF-A-mediated endocardial cushion formation: modulation by PECAM-1 and MMP-2. J Cell Biol. 2003, 160 (4): 605-615. 10.1083/jcb.200209014.
Article
PubMed Central
CAS
PubMed
Google Scholar
Abu-Sulaiman RM, Subaih B: Congenital heart disease in infants of diabetic mothers: echocardiographic study. Pediatr Cardiol. 2004, 25 (2): 137-140. 10.1007/s00246-003-0538-8.
Article
CAS
PubMed
Google Scholar
Eriksson UJ: Congenital malformations in diabetic animal models--a review. Diabetes Res. 1984, 1 (2): 57-66.
CAS
PubMed
Google Scholar
Pinter E, Haigh J, Nagy A, Madri JA: Hyperglycemia-induced vasculopathy in the murine conceptus is mediated via reductions of VEGF-A expression and VEGF receptor activation. Am J Pathol. 2001, 158 (4): 1199-1206.
Article
PubMed Central
CAS
PubMed
Google Scholar
Molin DG, Roest PA, Nordstrand H, Wisse LJ, Poelmann RE, Eriksson UJ, Gittenberger-De Groot AC: Disturbed morphogenesis of cardiac outflow tract and increased rate of aortic arch anomalies in the offspring of diabetic rats. Birth Defects Res A Clin Mol Teratol. 2004, 70 (12): 927-938. 10.1002/bdra.20101.
Article
CAS
PubMed
Google Scholar
Kirby ML, Stewart DE: Neural crest origin of cardiac ganglion cells in the chick embryo: identification and extirpation. Dev Biol. 1983, 97 (2): 433-443. 10.1016/0012-1606(83)90100-8.
Article
CAS
PubMed
Google Scholar
Kirby ML, Gale TF, Stewart DE: Neural crest cells contribute to normal aorticopulmonary septation. Science. 1983, 220 (4601): 1059-1061. 10.1126/science.6844926.
Article
CAS
PubMed
Google Scholar
Kirby ML, Aronstam RS, Buccafusco JJ: Changes in cholinergic parameters associated with failure of conotruncal septation in embryonic chick hearts after neural crest ablation. Circ Res. 1985, 56 (3): 392-401.
Article
CAS
PubMed
Google Scholar
Ferencz C, Rubin JD, McCarter RJ, Clark EB: Maternal diabetes and cardiovascular malformations: predominance of double outlet right ventricle and truncus arteriosus. Teratology. 1990, 41 (3): 319-326. 10.1002/tera.1420410309.
Article
CAS
PubMed
Google Scholar
Siman CM, Gittenberger-De Groot AC, Wisse B, Eriksson UJ: Malformations in offspring of diabetic rats: morphometric analysis of neural crest-derived organs and effects of maternal vitamin E treatment. Teratology. 2000, 61 (5): 355-367. 10.1002/(SICI)1096-9926(200005)61:5<355::AID-TERA7>3.0.CO;2-W.
Article
CAS
PubMed
Google Scholar
Suzuki N, Svensson K, Eriksson UJ: High glucose concentration inhibits migration of rat cranial neural crest cells in vitro. Diabetologia. 1996, 39 (4): 401-411. 10.1007/BF00400671.
Article
CAS
PubMed
Google Scholar
Crossin KL, Hoffman S: Expression of adhesion molecules during the formation and differentiation of the avian endocardial cushion tissue. Dev Biol. 1991, 145 (2): 277-286. 10.1016/0012-1606(91)90126-N.
Article
CAS
PubMed
Google Scholar
Okagawa H, Nakagawa M, Simada M: Immunolocalization of N-CAM in the heart of the early developing rat embryo. Anat Rec. 1995, 243 (2): 261-271. 10.1002/ar.1092430213.
Article
CAS
PubMed
Google Scholar
Bally-Cuif L, Goridis C, Santoni MJ: The mouse NCAM gene displays a biphasic expression pattern during neural tube development. Development. 1993, 117 (2): 543-552.
CAS
PubMed
Google Scholar
Shoba T, Dheen ST, Tay SS: Retinoic acid influences the expression of the neuronal regulatory genes Mash-1 and c-ret in the developing rat heart. Neurosci Lett. 2002, 318 (3): 129-132. 10.1016/S0304-3940(01)02491-0.
Article
CAS
PubMed
Google Scholar
Eriksson UJ, Cederberg J, Wentzel P: Congenital malformations in offspring of diabetic mothers--animal and human studies. Rev Endocr Metab Disord. 2003, 4 (1): 79-93. 10.1023/A:1021879504372.
Article
CAS
PubMed
Google Scholar
Jiao K, Kulessa H, Tompkins K, Zhou Y, Batts L, Baldwin HS, Hogan BL: An essential role of Bmp4 in the atrioventricular septation of the mouse heart. Genes Dev. 2003, 17 (19): 2362-2367. 10.1101/gad.1124803.
Article
PubMed Central
CAS
PubMed
Google Scholar
Ishii M, Han J, Yen HY, Sucov HM, Chai Y, Maxson RE: Combined deficiencies of Msx1 and Msx2 cause impaired patterning and survival of the cranial neural crest. Development. 2005, 132 (22): 4937-4950. 10.1242/dev.02072.
Article
CAS
PubMed
Google Scholar
Kwang SJ, Brugger SM, Lazik A, Merrill AE, Wu LY, Liu YH, Ishii M, Sangiorgi FO, Rauchman M, Sucov HM, Maas RL, Maxson RE: Msx2 is an immediate downstream effector of Pax3 in the development of the murine cardiac neural crest. Development. 2002, 129 (2): 527-538.
CAS
PubMed
Google Scholar
Conway SJ, Henderson DJ, Copp AJ: Pax3 is required for cardiac neural crest migration in the mouse: evidence from the splotch (Sp2H) mutant. Development. 1997, 124 (2): 505-514.
CAS
PubMed
Google Scholar
Franz T: Persistent truncus arteriosus in the Splotch mutant mouse. Anat Embryol (Berl). 1989, 180 (5): 457-464. 10.1007/BF00305120.
Article
CAS
Google Scholar
Stottmann RW, Choi M, Mishina Y, Meyers EN, Klingensmith J: BMP receptor IA is required in mammalian neural crest cells for development of the cardiac outflow tract and ventricular myocardium. Development. 2004, 131 (9): 2205-2218. 10.1242/dev.01086.
Article
PubMed Central
CAS
PubMed
Google Scholar
Nakajima Y, Yamagishi T, Hokari S, Nakamura H: Mechanisms involved in valvuloseptal endocardial cushion formation in early cardiogenesis: roles of transforming growth factor (TGF)-beta and bone morphogenetic protein (BMP). Anat Rec. 2000, 258 (2): 119-127. 10.1002/(SICI)1097-0185(20000201)258:2<119::AID-AR1>3.0.CO;2-U.
Article
CAS
PubMed
Google Scholar
Markwald RR, Wessels A: Overview of heart development. Formation of the heart and its regulation. Edited by: RB TRJR. 2001, Birkhauser, Boston , 1-22.
Chapter
Google Scholar
Chan-Thomas PS, Thompson RP, Robert B, Yacoub MH, Barton PJ: Expression of homeobox genes Msx-1 (Hox-7) and Msx-2 (Hox-8) during cardiac development in the chick. Dev Dyn. 1993, 197 (3): 203-216.
Article
CAS
PubMed
Google Scholar
Creazzo TL, Godt RE, Leatherbury L, Conway SJ, Kirby ML: Role of cardiac neural crest cells in cardiovascular development. Annu Rev Physiol. 1998, 60: 267-286. 10.1146/annurev.physiol.60.1.267.
Article
CAS
PubMed
Google Scholar
Kaufman MH: The Atlas of Mouse Development. 1992, New York, NY , Academic Press
Google Scholar
Sissman NJ: Developmental landmarks in cardiac morphogenesis: comparative chronology. Am J Cardiol. 1970, 25 (2): 141-148. 10.1016/0002-9149(70)90575-8.
Article
CAS
PubMed
Google Scholar
Srinivasan S, Baldwin HS, Aristizabal O, Kwee L, Labow M, Artman M, Turnbull DH: Noninvasive, in utero imaging of mouse embryonic heart development with 40-MHz echocardiography. Circulation. 1998, 98 (9): 912-918.
Article
CAS
PubMed
Google Scholar
Kumar SD, Tay SS: Changes in peptidergic nerves in the atrioventricular valves of streptozotocin-induced diabetic rats: a confocal microscopy study. Anat Rec. 2000, 258 (3): 277-285. 10.1002/(SICI)1097-0185(20000301)258:3<277::AID-AR7>3.0.CO;2-U.
Article
CAS
PubMed
Google Scholar
Livak KJ, Schmittgen TD: Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. Methods. 2001, 25 (4): 402-408. 10.1006/meth.2001.1262.
Article
CAS
PubMed
Google Scholar
Liao DM, Ng YK, Tay SS, Ling EA, Dheen ST: Altered gene expression with abnormal patterning of the telencephalon in embryos of diabetic Albino Swiss mice. Diabetologia. 2004, 47 (3): 523-531. 10.1007/s00125-004-1351-5.
Article
CAS
PubMed
Google Scholar
Fu J, Tay SS, Ling EA, Dheen ST: High glucose alters the expression of genes involved in proliferation and cell-fate specification of embryonic neural stem cells. Diabetologia. 2006, 49 (5): 1027-1038. 10.1007/s00125-006-0153-3.
Article
CAS
PubMed
Google Scholar
Kumar SD, Tay SS: Ultrastructural changes in the atrioventricular valves of streptozotocin-induced diabetic rats. J Hirnforsch. 1999, 39 (4): 559-566.
CAS
PubMed
Google Scholar
Takeshima H, Komazaki S, Hirose K, Nishi M, Noda T, Iino M: Embryonic lethality and abnormal cardiac myocytes in mice lacking ryanodine receptor type 2. Embo J. 1998, 17 (12): 3309-3316. 10.1093/emboj/17.12.3309.
Article
PubMed Central
CAS
PubMed
Google Scholar
Sund M, Ylonen R, Tuomisto A, Sormunen R, Tahkola J, Kvist AP, Kontusaari S, Autio-Harmainen H, Pihlajaniemi T: Abnormal adherence junctions in the heart and reduced angiogenesis in transgenic mice overexpressing mutant type XIII collagen. Embo J. 2001, 20 (18): 5153-5164. 10.1093/emboj/20.18.5153.
Article
PubMed Central
CAS
PubMed
Google Scholar
Adams MM, Mulinare J, Dooley K: Risk factors for conotruncal cardiac defects in Atlanta. J Am Coll Cardiol. 1989, 14 (2): 432-442. 10.1016/0735-1097(89)90199-X.
Article
CAS
PubMed
Google Scholar
Meyer-Wittkopf M, Simpson JM, Sharland GK: Incidence of congenital heart defects in fetuses of diabetic mothers: a retrospective study of 326 cases. Ultrasound Obstet Gynecol. 1996, 8 (1): 8-10. 10.1046/j.1469-0705.1996.08010008.x.
Article
CAS
PubMed
Google Scholar
Phelan SA, Ito M, Loeken MR: Neural tube defects in embryos of diabetic mice: role of the Pax-3 gene and apoptosis. Diabetes. 1997, 46 (7): 1189-1197. 10.2337/diabetes.46.7.1189.
Article
CAS
PubMed
Google Scholar
Dinleyici EC, Tekin N, Dinleyici M, Kilic Z, Adapinar B, Aksit MA: Severe fatal course of axial mesodermal dysplasia spectrum associated with complex cardiac defect in an infant of a mother with insulin dependent diabetes. Am J Med Genet A. 2007, 143 (18): 2156-2159.
Article
Google Scholar
Smoak IW: Hyperglycemia-induced TGFbeta and fibronectin expression in embryonic mouse heart. Dev Dyn. 2004, 231 (1): 179-189. 10.1002/dvdy.20123.
Article
CAS
PubMed
Google Scholar
Roest PA, van Iperen L, Vis S, Wisse LJ, Poelmann RE, Steegers-Theunissen RP, Molin DG, Eriksson UJ, Gittenberger-De Groot AC: Exposure of neural crest cells to elevated glucose leads to congenital heart defects, an effect that can be prevented by N-acetylcysteine. Birth Defects Res A Clin Mol Teratol. 2007, 79 (3): 231-235. 10.1002/bdra.20341.
Article
CAS
PubMed
Google Scholar
Schafer K, Neuhaus P, Kruse J, Braun T: The homeobox gene Lbx1 specifies a subpopulation of cardiac neural crest necessary for normal heart development. Circ Res. 2003, 92 (1): 73-80. 10.1161/01.RES.0000050587.76563.A5.
Article
PubMed
Google Scholar
Suzuki A, Ueno N, Hemmati-Brivanlou A: Xenopus msx1 mediates epidermal induction and neural inhibition by BMP4. Development. 1997, 124 (16): 3037-3044.
CAS
PubMed
Google Scholar
Cederberg J, Picard JJ, Eriksson UJ: Maternal diabetes in the rat impairs the formation of neural-crest derived cranial nerve ganglia in the offspring. Diabetologia. 2003, 46 (9): 1245-1251. 10.1007/s00125-003-1100-1.
Article
CAS
PubMed
Google Scholar
Aybar MJ, Mayor R: Early induction of neural crest cells: lessons learned from frog, fish and chick. Curr Opin Genet Dev. 2002, 12 (4): 452-458. 10.1016/S0959-437X(02)00325-8.
Article
CAS
PubMed
Google Scholar
Knecht AK, Bronner-Fraser M: Induction of the neural crest: a multigene process. Nat Rev Genet. 2002, 3 (6): 453-461. 10.1038/nrm832.
Article
CAS
PubMed
Google Scholar
Camenisch TD, Molin DG, Person A, Runyan RB, Gittenberger-de Groot AC, McDonald JA, Klewer SE: Temporal and distinct TGFbeta ligand requirements during mouse and avian endocardial cushion morphogenesis. Dev Biol. 2002, 248 (1): 170-181. 10.1006/dbio.2002.0731.
Article
CAS
PubMed
Google Scholar
Han M, Yang X, Farrington JE, Muneoka K: Digit regeneration is regulated by Msx1 and BMP4 in fetal mice. Development. 2003, 130 (21): 5123-5132. 10.1242/dev.00710.
Article
CAS
PubMed
Google Scholar
Wang J, Sridurongrit S, Dudas M, Thomas P, Nagy A, Schneider MD, Epstein JA, Kaartinen V: Atrioventricular cushion transformation is mediated by ALK2 in the developing mouse heart. Dev Biol. 2005, 286 (1): 299-310. 10.1016/j.ydbio.2005.07.035.
Article
PubMed Central
CAS
PubMed
Google Scholar
Epstein JA, Li J, Lang D, Chen F, Brown CB, Jin F, Lu MM, Thomas M, Liu E, Wessels A, Lo CW: Migration of cardiac neural crest cells in Splotch embryos. Development. 2000, 127 (9): 1869-1878.
CAS
PubMed
Google Scholar