Maternal diabetes induces congenital heart defects in mice by altering the expression of genes involved in cardiovascular development

Table 3 Frequencies for cardiac and extra-cardiac malformations in the embryos from control and diabetic mice.

	Control (n = 60)	Diabetes (n = 120)
No. of embryos with cardiac malformations	0	12 (10.0%)
No. of embryos with extra-cardiac malformations^a	0	15 (12.5%)

^a Extra-cardiac malformation such as neural tube defects, including exencephaly, anaencephaly and spina bifida.