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  1. Obstructive sleep apnea (OSA) and type 2 diabetes (T2D) are associated with endothelial dysfunction a main predictor of late cardiovascular (CV) events. Despite the high prevalence of OSA in patients with T2D,...

    Authors: Vanessa Bironneau, François Goupil, Pierre Henri Ducluzeau, Marc Le Vaillant, Pierre Abraham, Samir Henni, Séverine Dubois, Audrey Paris, Pascaline Priou, Nicole Meslier, Claire Sanguin, Wojciech Trzépizur, Ramaroson Andriantsitohaina, Maria Carmen Martinez and Frédéric Gagnadoux
    Citation: Cardiovascular Diabetology 2017 16:39
  2. We aimed to (1) assess the association between lipoprotein(a) [Lp(a)] concentration and incident type-2 diabetes in the Bruneck study, a prospective population-based study, and (2) combine findings with eviden...

    Authors: Ellie Paige, Katya L. Masconi, Sotirios Tsimikas, Florian Kronenberg, Peter Santer, Siegfried Weger, Johann Willeit, Stefan Kiechl and Peter Willeit
    Citation: Cardiovascular Diabetology 2017 16:38
  3. To establish if aerobic exercise training is associated with beneficial effects on clinical outcomes and glycaemic profile in people with type II diabetes.

    Authors: Aimee Grace, Erick Chan, Francesco Giallauria, Petra L. Graham and Neil A. Smart
    Citation: Cardiovascular Diabetology 2017 16:37
  4. Subclinical left ventricular (LV) diastolic dysfunction in type 2 diabetes (T2D) is a common finding and represents an early sign of diabetic cardiomyopathy. However, the relationship between LV diastolic dysf...

    Authors: Juri Park, Jin-Seok Kim, Seong Hwan Kim, Sunwon Kim, Sang Yup Lim, Hong-Euy Lim, Goo-Yeong Cho, Ki-Chul Sung, Jang-Young Kim, Inkyung Baik, Kwang Kon Koh, Jung Bok Lee, Seung Ku Lee and Chol Shin
    Citation: Cardiovascular Diabetology 2017 16:36
  5. The 2nd Cardiovascular Outcome Trial (CVOT) Summit of the Diabetes and Cardiovascular Disease (D&CVD) EASD Study Group was held on the 20th–21st October 2016 in Munich. This second Summit was organized in ligh...

    Authors: Oliver Schnell, Eberhard Standl, Doina Catrinoiu, Stefano Genovese, Nebojsa Lalic, Jan Skra, Paul Valensi, Dario Rahelic and Antonio Ceriello
    Citation: Cardiovascular Diabetology 2017 16:35

    The Correction to this article has been published in Cardiovascular Diabetology 2017 16:135

  6. An enhanced thrombotic environment and premature atherosclerosis are key factors for the increased cardiovascular risk in diabetes. The occlusive vascular thrombus, formed secondary to interactions between pla...

    Authors: Katherine Kearney, Darren Tomlinson, Kerrie Smith and Ramzi Ajjan
    Citation: Cardiovascular Diabetology 2017 16:34
  7. Vascular dysfunction is a pivotal event in the development of diabetes-associated vascular disease. Increased inflammation and oxidative stress are major contributors to vascular dysfunction. Nrf2, a master re...

    Authors: Arpeeta Sharma, Luddwi Rizky, Nada Stefanovic, Mitchel Tate, Rebecca H. Ritchie, Keith W. Ward and Judy B. de Haan
    Citation: Cardiovascular Diabetology 2017 16:33
  8. Accumulation of epicardial fat (EF) is associated with increased cardio-metabolic risks and coronary events, independently of traditional cardiovascular risk factors. Therefore, the reduction of EF volume (EFV...

    Authors: Ryotaro Bouchi, Masahiro Terashima, Yuriko Sasahara, Masahiro Asakawa, Tatsuya Fukuda, Takato Takeuchi, Yujiro Nakano, Masanori Murakami, Isao Minami, Hajime Izumiyama, Koshi Hashimoto, Takanobu Yoshimoto and Yoshihiro Ogawa
    Citation: Cardiovascular Diabetology 2017 16:32
  9. Incretin-based agents, including dipeptidyl peptidase-4 inhibitors (DPP-4Is) and glucagon-like peptide-1 agonists (GLP-1As), work via GLP-1 receptor for hyperglycemic control directly or indirectly, but have d...

    Authors: Zeqing Zhang, Xi Chen, Puhan Lu, Jianhua Zhang, Yongping Xu, Wentao He, Mengni Li, Shujun Zhang, Jing Jia, Shiying Shao, Junhui Xie, Yan Yang and Xuefeng Yu
    Citation: Cardiovascular Diabetology 2017 16:31
  10. Risk of type 2 diabetes mellitus (T2DM) is increased in metabolically obese but normal-weight people. However, we have limited knowledge of how to prevent T2DM in normal-weight people. We aimed to evaluate the...

    Authors: Ming Zhang, Bingyuan Wang, Yu Liu, Xizhuo Sun, Xinping Luo, Chongjian Wang, Linlin Li, Lu Zhang, Yongcheng Ren, Yang Zhao, Junmei Zhou, Chengyi Han, Jingzhi Zhao and Dongsheng Hu
    Citation: Cardiovascular Diabetology 2017 16:30
  11. Physiologic determinants, such as pulse pressure [difference between systolic blood pressure (SBP) and diastolic BP (DBP)], mean arterial pressure (2/3 DBP + 1/3 SBP), and double product [beats per minute (bpm...

    Authors: Michael Pfeifer, Raymond R. Townsend, Michael J. Davies, Ujjwala Vijapurkar and Jimmy Ren
    Citation: Cardiovascular Diabetology 2017 16:29
  12. Diabetic cardiomyopathy (DCM) is a cardiac dysfunction which affects approximately 12% of diabetic patients, leading to overt heart failure and death. However, there is not an efficient and specific methodolog...

    Authors: A. Lorenzo-Almorós, J. Tuñón, M. Orejas, M. Cortés, J. Egido and Ó. Lorenzo
    Citation: Cardiovascular Diabetology 2017 16:28
  13. Fewer circulating endothelial progenitor cells (EPCs) and increased plasma (C-term) stromal cell-derived factor 1α (SDF-1α), a substrate of DPP-4, are biomarkers, and perhaps mediators, of cardiovascular risk ...

    Authors: Alessandra Dei Cas, Valentina Spigoni, Monia Cito, Raffaella Aldigeri, Valentina Ridolfi, Elisabetta Marchesi, Michela Marina, Eleonora Derlindati, Rosalia Aloe, Riccardo C. Bonadonna and Ivana Zavaroni
    Citation: Cardiovascular Diabetology 2017 16:27
  14. The sodium–glucose cotransporter 2 inhibitor, dapagliflozin, has been shown to improve diabetic control and reduce blood pressure in patients with type 2 diabetes mellitus. Its effects on micro- and macrovascu...

    Authors: Christian Ott, Agnes Jumar, Kristina Striepe, Stefanie Friedrich, Marina V. Karg, Peter Bramlage and Roland E. Schmieder
    Citation: Cardiovascular Diabetology 2017 16:26
  15. Vascular calcification (VC) is common in type 2 diabetes, and is associated with cardiovascular complications. Recent preclinical data suggest that metformin inhibits VC both in vitro and in animal models. How...

    Authors: Aurélien Mary, Agnes Hartemann, Sophie Liabeuf, Carole Elodie Aubert, Salim Kemel, Joe Elie Salem, Philippe Cluzel, Aurélie Lenglet, Ziad A. Massy, Jean-Daniel Lalau, Romuald Mentaverri, Olivier Bourron and Saïd Kamel
    Citation: Cardiovascular Diabetology 2017 16:24
  16. To report the long-term safety and efficacy data of a third generation drug eluting stent (DES) with biodegradable polymer in the complex patient population of diabetes mellitus after a follow-up period of 5 ...

    Authors: Marcus Wiemer, Sinisa Stoikovic, Alexander Samol, Zisis Dimitriadis, Juan M. Ruiz-Nodar, Ralf Birkemeyer, Jacques Monsegu, Gérard Finet, David Hildick-Smith, Damras Tresukosol, Enrique Garcia Novo, Jacques J. Koolen, Emanuele Barbato and Gian Battista Danzi
    Citation: Cardiovascular Diabetology 2017 16:23

    The Erratum to this article has been published in Cardiovascular Diabetology 2017 16:59

  17. Use of dipeptidyl peptidase-4 inhibitors (DPP4-i) for the treatment of type 2 diabetes (T2D) has been associated with a possible increase in the risk for heart failure (HF). B-type natriuretic peptide (BNP), w...

    Authors: Gian Paolo Fadini, Benedetta Maria Bonora, Mattia Albiero, Martina Zaninotto, Mario Plebani and Angelo Avogaro
    Citation: Cardiovascular Diabetology 2017 16:22
  18. It is unclear whether obesity and type 2 diabetes (T2D), either alone or in combination, induce left ventricular hypertrophy (LVH) independent of hypertension. In the current study, we provide clarity on this ...

    Authors: Kirstie A. De Jong, Juliane K. Czeczor, Smithamol Sithara, Kevin McEwen, Gary D. Lopaschuk, Alan Appelbe, Kimberly Cukier, Mark Kotowicz and Sean L. McGee
    Citation: Cardiovascular Diabetology 2017 16:21

    The Erratum to this article has been published in Cardiovascular Diabetology 2017 16:53

  19. Brain-derived neurotrophic factor (BDNF) exerts beneficial effects not only on diabetic neuropathies but also on cardiovascular injury. There is argument regarding the levels of serum BDNF in patients with dia...

    Authors: Kazuo Furukawa, Ichiro Fuse, Yuriko Iwakura, Hidekazu Sotoyama, Osamu Hanyu, Hiroyuki Nawa, Hirohito Sone and Nobuyuki Takei
    Citation: Cardiovascular Diabetology 2017 16:20
  20. Many cardioprotective pharmacological agents failed to exert their protective effects in diabetic hearts subjected to myocardial ischemia/reperfusion (MI/R). Identify the molecular basis linking diabetes with ...

    Authors: Mingge Ding, Qianqian Dong, Zhenghua Liu, Zheng Liu, Yinxian Qu, Xing Li, Cong Huo, Xin Jia, Feng Fu and Xiaoming Wang
    Citation: Cardiovascular Diabetology 2017 16:19

    The Erratum to this article has been published in Cardiovascular Diabetology 2017 16:60

  21. Interleukin-22 (IL-22) has beneficial effects on body weight, insulin resistance and inflammation in different mouse models, but its relevance for the development of type 2 diabetes in humans is unknown. We ai...

    Authors: Christian Herder, Julia M. Kannenberg, Maren Carstensen-Kirberg, Cornelia Huth, Christa Meisinger, Wolfgang Koenig, Annette Peters, Wolfgang Rathmann, Michael Roden and Barbara Thorand
    Citation: Cardiovascular Diabetology 2017 16:17
  22. To determine the association between urinary N-acetyl-β-d-glucosaminidase (NAG), a marker of renal tubulopathy, and carotid intima-media thickness (IMT) and plaques in patients with type 2 diabetes mellitus (T2D)...

    Authors: So Ra Kim, Yong-ho Lee, Sang-Guk Lee, Eun Seok Kang, Bong-Soo Cha and Byung-Wan Lee
    Citation: Cardiovascular Diabetology 2017 16:16
  23. Enhanced advanced glycation end products deposition within myocardial tissue may cause diastolic dysfunction. However, whether this is related to left ventricular hypertrophy or inappropriate left ventricular ...

    Authors: Chun-Cheng Wang, Yao-Chang Wang, Guei-Jane Wang, Ming-Yi Shen, Yen-Lin Chang, Show-Yih Liou, Hung-Chih Chen, An-Sheng Lee, Kuan-Cheng Chang, Wei-Yu Chen and Chiz-Tzung Chang
    Citation: Cardiovascular Diabetology 2017 16:15
  24. To investigate the relationship among body mass index (BMI), cardiometabolic risk and coronary artery disease (CAD) among patients undergoing coronary computed tomography angiography (CTA).

    Authors: Edward A. Hulten, Marcio Sommer Bittencourt, Ryan Preston, Avinainder Singh, Carla Romagnolli, Brian Ghoshhajra, Ravi Shah, Siddique Abbasi, Suhny Abbara, Khurram Nasir, Michael Blaha, Udo Hoffmann, Marcelo F. Di Carli and Ron Blankstein
    Citation: Cardiovascular Diabetology 2017 16:14
  25. Studies of dipeptidyl peptidase (DPP)-4 inhibitors report heterogeneous effects on endothelial function in patients with type 2 diabetes (T2D). This study assessed the effects of the DPP-4 inhibitor linaglipti...

    Authors: Thomas Jax, Alin Stirban, Arne Terjung, Habib Esmaeili, Andreas Berk, Sandra Thiemann, Robert Chilton, Maximilian von Eynatten and Nikolaus Marx
    Citation: Cardiovascular Diabetology 2017 16:13
  26. Endothelial dysfunction plays a critical role in the development of type 2 diabetes (T2DM). T-cadherin (T-cad) has gained recognition as a regulator of endothelial cell (EC) function. The present study examine...

    Authors: Han Wang, Ling Tao, Anastasia Ambrosio, Wenjun Yan, Ross Summer, Wayne Bond Lau, Yajing Wang and Xinliang Ma
    Citation: Cardiovascular Diabetology 2017 16:12
  27. Diabetes and cardiovascular disease develop in concert with metabolic abnormalities mirroring and causing changes in the vasculature, particularly the microcirculation. The microcirculation can be affected in ...

    Authors: Dagmar Fuchs, Pepijn P. Dupon, Laura A. Schaap and Richard Draijer
    Citation: Cardiovascular Diabetology 2017 16:11
  28. Hyperglycaemia, hypertension, dyslipidemia and insulin resistance collectively impact on the myocardium of people with diabetes, triggering molecular, structural and myocardial abnormalities. These have been s...

    Authors: Jason Kar Sheng Lew, James T. Pearson, Daryl O. Schwenke and Rajesh Katare
    Citation: Cardiovascular Diabetology 2017 16:10
  29. Obese and diabetic individuals are at increased risk for impairments in diastolic relaxation and heart failure with preserved ejection fraction. The impairments in diastolic relaxation are especially pronounce...

    Authors: Javad Habibi, Annayya R. Aroor, James R. Sowers, Guanghong Jia, Melvin R. Hayden, Mona Garro, Brady Barron, Eric Mayoux, R. Scott Rector, Adam Whaley-Connell and Vincent G. DeMarco
    Citation: Cardiovascular Diabetology 2017 16:9
  30. The sodium-glucose co-transporter-2 (SGLT-2) inhibitors have been reported to increase both low-density lipoprotein (LDL) and high-density lipoprotein (HDL)-cholesterol (C). This study aimed to determine how S...

    Authors: Toshiyuki Hayashi, Tomoyasu Fukui, Noriko Nakanishi, Saki Yamamoto, Masako Tomoyasu, Anna Osamura, Makoto Ohara, Takeshi Yamamoto, Yasuki Ito and Tsutomu Hirano
    Citation: Cardiovascular Diabetology 2017 16:8

    The Correction to this article has been published in Cardiovascular Diabetology 2017 16:149

  31. Adenosine-free coronary pressure wire metrics have been proposed to test the functional significance of coronary artery lesions, but it is unexplored whether their diagnostic performance might be altered in pa...

    Authors: Giuseppe Gargiulo, Eugenio Stabile, Marco Ferrone, Emanuele Barbato, Frederik M. Zimmermann, Julien Adjedj, Barry Hennigan, Mitsuaki Matsumura, Nils P. Johnson, William F. Fearon, Allen Jeremias, Bruno Trimarco and Giovanni Esposito
    Citation: Cardiovascular Diabetology 2017 16:7
  32. While glucagon-like peptide-1 receptor agonists (GLP-1 RAs) are known to increase heart rate (HR), it is insufficiently recognized that the extent varies greatly between the various agonists and is affected by...

    Authors: Martin Lorenz, Francesca Lawson, David Owens, Denis Raccah, Christine Roy-Duval, Anne Lehmann, Riccardo Perfetti and Lawrence Blonde
    Citation: Cardiovascular Diabetology 2017 16:6
  33. Gestational diabetes mellitus (GDM) is a significant risk factor for cardiovascular disease (CVD) in later life, but the mechanism remains unclear. Adipokine imbalance in the presence of metabolic dysfunction ...

    Authors: Tove Lekva, Annika Elisabet Michelsen, PÃ¥l Aukrust, Tore Henriksen, Jens Bollerslev and Thor Ueland
    Citation: Cardiovascular Diabetology 2017 16:5
  34. To investigate the effects of dyslipidemia and statin therapy on progression of diabetic retinopathy and diabetic macular edema in patients with type 2 diabetes.

    Authors: Yoo-Ri Chung, Sung Wook Park, Shin-Young Choi, Seung Woo Kim, Ka Young Moon, Jeong Hun Kim and Kihwang Lee
    Citation: Cardiovascular Diabetology 2017 16:4
  35. Diabetes mellitus (DM) and essential hypertension are common conditions that are frequently present together. Both are considered risk factors for cardiovascular disease and microvascular complications and the...

    Authors: Alon Grossman and Ehud Grossman
    Citation: Cardiovascular Diabetology 2017 16:3
  36. Endothelial dysfunction is an early marker of cardiovascular disease so endothelial and arterial stiffness indexes are good indicators of vascular health. We aimed to assess whether the presence of diabetic fo...

    Authors: Antonino Tuttolomondo, Alessandra Casuccio, Giovanni Guercio, Carlo Maida, Alessandro Del Cuore, Domenico Di Raimondo, Irene Simonetta, Danilo Di Bona, Rosaria Pecoraro, Vittoriano Della Corte, Eliana Gulotta, Gaspare Gulotta and Antonio Pinto
    Citation: Cardiovascular Diabetology 2017 16:2
  37. Representative data on the secular trends in cardiovascular disease (CVD) are limited in Asian populations with diabetes. We aimed to estimate the temporal trends in cardiovascular complications using Korean n...

    Authors: Chang Hee Jung, Jin Ook Chung, Kyungdo Han, Seung-Hyun Ko, Kyung Soo Ko and Joong-Yeol Park
    Citation: Cardiovascular Diabetology 2017 16:1
  38. Diastolic dysfunction is a major cause of morbidity in obese individuals. We aimed to assess the ability of magnetic resonance imaging (MRI) derived left atrial (LA) strain to detect early diastolic dysfunctio...

    Authors: Morgane Evin, Kathryn M. Broadhouse, Fraser M. Callaghan, Rachel T. McGrath, Sarah Glastras, Rebecca Kozor, Samantha L. Hocking, Jérôme Lamy, Alban Redheuil, Nadjia Kachenoura, Greg R. Fulcher, Gemma A. Figtree and Stuart M. Grieve
    Citation: Cardiovascular Diabetology 2016 15:164
  39. Individuals with peripheral artery disease (PAD) often have reduced physical activity, which may increase the future risk of diabetes mellitus. Although diabetes is a risk factor for PAD, whether low ankle-bra...

    Authors: Simin Hua, Laura R. Loehr, Hirofumi Tanaka, Gerardo Heiss, Josef Coresh, Elizabeth Selvin and Kunihiro Matsushita
    Citation: Cardiovascular Diabetology 2016 15:163
  40. Liraglutide, a GLP-1 analogue, exerts several beneficial non-glycemic effects in patients with type-2 diabetes (T2DM), such as those on body weight, blood pressure, plasma lipids and inflammation markers. Howe...

    Authors: Manfredi Rizzo, Ali A. Rizvi, Angelo Maria Patti, Dragana Nikolic, Rosaria Vincenza Giglio, Giuseppa Castellino, Giovanni Li Volti, Massimiliano Caprio, Giuseppe Montalto, Vincenzo Provenzano, Stefano Genovese and Antonio Ceriello
    Citation: Cardiovascular Diabetology 2016 15:162
  41. Abnormal proliferation and migration of vascular smooth muscle cells (VSMCs) is a major contributor to the development of atherosclerotic process. In a previous work, we demonstrated that the insulin receptor ...

    Authors: N. Beneit, C. E. Fernández-García, J. L. Martín-Ventura, L. Perdomo, Ó. Escribano, J. B. Michel, G. García-Gómez, S. Fernández, S. Díaz-Castroverde, J. Egido, A. Gómez-Hernández and M. Benito
    Citation: Cardiovascular Diabetology 2016 15:161
  42. There are limited data regarding the effect of diabetes mellitus (DM) on the risks of both appropriate and inappropriate implantable cardioverter defibrillator (ICD) therapy. The present study was designed to ...

    Authors: Hillel Steiner, Michael Geist, Ilan Goldenberg, Mahmoud Suleiman, Michael Glikson, Alexander Tenenbaum, Moshe Swissa, Enrique Z. Fisman, Gregory Golovchiner, Boris Strasberg and Alon Barsheshet
    Citation: Cardiovascular Diabetology 2016 15:160
  43. Visceral fat plays a central role in the development of metabolic syndrome and atherosclerotic cardiovascular diseases. The association of visceral fat accumulation with cardio-metabolic diseases has been repo...

    Authors: Yoshinari Obata, Norikazu Maeda, Yuya Yamada, Koji Yamamoto, Seiji Nakamura, Masaya Yamaoka, Yoshimitsu Tanaka, Shigeki Masuda, Hirofumi Nagao, Shiro Fukuda, Yuya Fujishima, Shunbun Kita, Hitoshi Nishizawa, Tohru Funahashi, Ken-ichi Matsubara, Yuji Matsuzawa…
    Citation: Cardiovascular Diabetology 2016 15:159
  44. Smoking is associated with increased macrovascular and microvascular complications in people with diabetes. In addition to other concomitant vascular perturbations, it also seems to influence the cardiometabol...

    Authors: Debasish Kar, Clare Gillies, Francesco Zaccardi, David Webb, Samuel Seidu, Solomon Tesfaye, Melanie Davies and Kamlesh Khunti
    Citation: Cardiovascular Diabetology 2016 15:158
  45. The potential benefit of SGLT2 inhibitors in metabolic syndrome is with prediabetic stage unclear. This work was undertaken to investigate the non-glycemic effect of empagliflozin on metabolic syndrome rats wi...

    Authors: Hiroaki Kusaka, Nobutaka Koibuchi, Yu Hasegawa, Hisao Ogawa and Shokei Kim-Mitsuyama
    Citation: Cardiovascular Diabetology 2016 15:157
  46. Hyperinsulinemia and insulin resistance have been recently recognized as an important cause of atherosclerosis. Clinical studies have also found that expression of the estrogen receptor is closely related to t...

    Authors: Jia Min, Zhong Weitian, Cai Peng, Peng Yan, Zhang Bo, Wang Yan, Bai Yun and Wang Xukai
    Citation: Cardiovascular Diabetology 2016 15:156
  47. The leading cause of death among the obese population is heart failure and stroke prompted by structural and functional changes in the heart. The molecular mechanisms that underlie obesity-related cardiac remo...

    Authors: Elisa Lucas, Rocio Vila-Bedmar, Alba C. Arcones, Marta Cruces-Sande, Victoria Cachofeiro, Federico Mayor Jr. and Cristina Murga
    Citation: Cardiovascular Diabetology 2016 15:155
  48. Results of longitudinal researches regarding the temporal relationship between dyslipidemia and insulin resistance (IR) are inconsistent. This study assessed temporal relationships of blood lipids with IR and ...

    Authors: Tianshu Han, Yu Cheng, Shuang Tian, Li Wang, Xi Liang, Wei Duan, Lixin Na and Changhao Sun
    Citation: Cardiovascular Diabetology 2016 15:154

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