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  1. To evaluate the impact of different definitions of metabolic syndrome (MetS) and their components on the risk of sudden cardiac death (SCD) among the Iranian population according to the World Health Organizati...

    Authors: Soroush Masrouri, Seyyed Saeed Moazzeni, Neda Cheraghloo, Fereidoun Azizi and Farzad Hadaegh
    Citation: Cardiovascular Diabetology 2022 21:269
    Content type: Research Published on:

  2. An “obesity paradox” for mortality has been shown in chronic disorders such as diabetes, and attributed to methodological bias, including the use of body mass index (BMI) for obesity definition. This analysis ...

    Authors: Emanuela Orsi, Anna Solini, Giuseppe Penno, Enzo Bonora, Cecilia Fondelli, Roberto Trevisan, Monica Vedovato, Franco Cavalot, Olga Lamacchia, Jonida Haxhi, Antonio Nicolucci and Giuseppe Pugliese
    Citation: Cardiovascular Diabetology 2022 21:266
    Content type: Research Published on:

  3. Dimethylarginine dimethylaminohydrolase (DDAH) 1 maintains the bioavailability of nitric oxide by degrading asymmetric dimethylarginine (ADMA). Here, we aimed to investigate the effect of haptoglobin (Hp) geno...

    Authors: Shiyun Wang, Zixuan Deng, Hong Zhang, Rong Zhang, Dandan Yan, Xiaojiao Zheng, Weiping Jia and Cheng Hu
    Citation: Cardiovascular Diabetology 2022 21:265
    Content type: Research Published on:

  4. Triglyceride-glucose (TyG) index has been proposed as a simple and credible surrogate for insulin resistance and an independent predictor of cardiovascular outcomes. Due to lack of data on TyG index in stroke,...

    Authors: Takao Hoshino, Takafumi Mizuno, Kentaro Ishizuka, Shuntaro Takahashi, Satoko Arai, Sono Toi and Kazuo Kitagawa
    Citation: Cardiovascular Diabetology 2022 21:264
    Content type: Research Published on:

  5. Dyslipidemia in patients with type 2 diabetes (DMT2) is one of the worst controlled worldwide, with only about 1/4 of patients being on the low-density lipoprotein cholesterol (LDL-C) target. There are many re...

    Authors: Maciej Banach, Stanisław Surma, Zeljko Reiner, Niki Katsiki, Peter E. Penson, Zlatko Fras, Amirhossein Sahebkar, Francesco Paneni, Manfredi Rizzo and John Kastelein
    Citation: Cardiovascular Diabetology 2022 21:263
    Content type: Review Published on:

  6. Arterial stiffness, glycemic control and blood pressure are risk factors of macrovascular complications in type 2 diabetes. This study aimed to investigate the combined association of arterial stiffness, glyce...

    Authors: Zhiyuan Wu, Siqi Yu, Haiping Zhang, Zheng Guo, Yulu Zheng, Zongkai Xu, Zhiwei Li, Xiangtong Liu, Xia Li, Shuo Chen, Jingbo Zhang, Lixin Tao and Xiuhua Guo
    Citation: Cardiovascular Diabetology 2022 21:262
    Content type: Research Published on:

  7. Enhanced de-novo collagen type VI (COL VI) formation has been associated with kidney and cardiovascular fibrosis. We hypothesized that endotrophin (ETP), a product specifically generated during collagen type V...

    Authors: Daniel Guldager Kring Rasmussen, Michael K. Hansen, Joseph Blair, Timothy A. Jatkoe, Bruce Neal, Morten A. Karsdal and Federica Genovese
    Citation: Cardiovascular Diabetology 2022 21:261
    Content type: Research Published on:

  8. The triglyceride glucose (TyG) index is an alternative to insulin resistance (IR) as an early indicator of worsening heart failure (HF). Patients with secondary mitral regurgitation (sMR) often experience prog...

    Authors: Haozhang Huang, Qiang Li, Jiulin Liu, Linfang Qiao, Shiqun Chen, Wenguang Lai, Yu Kang, Xiaozhao Lu, Yang Zhou, Yibo He, Jiyan Chen, Ning Tan, Jin Liu and Yong Liu
    Citation: Cardiovascular Diabetology 2022 21:260
    Content type: Research Published on:

  9. Coronary atherosclerosis can lead to serious cardiovascular events. In type 2 diabetes (T2DM) patients, the effects of clinical factors on coronary atherosclerosis have not been fully elucidated. We used a clu...

    Authors: Yu Jiang, Zhi-Gang Yang, Jin Wang, Rui Shi, Pei-Lun Han, Wen-Lei Qian, Wei-Feng Yan and Yuan Li
    Citation: Cardiovascular Diabetology 2022 21:259
    Content type: Research Published on:

  10. Diabetes and prediabetes are known risk factors for cardiovascular disease and associated with increased mortality risk. Whether patients with a random elevated blood glucose level but no history of diabetes a...

    Authors: Catarina Djupsjö, Jeanette Kuhl, Tomas Andersson, Magnus Lundbäck, Martin J. Holzmann and Thomas Nyström
    Citation: Cardiovascular Diabetology 2022 21:258
    Content type: Research Published on:

    The Correction to this article has been published in Cardiovascular Diabetology 2022 21:292

  11. Subjects with Type 1 diabetes mellitus (T1DM) have an increased incidence of heart failure (HF). Several pathophysiological mechanisms have been involved in its development. The aim of this study was to analyz...

    Authors: Carlos Puig-Jové, Josep Julve, Esmeralda Castelblanco, M Teresa Julián, Núria Amigó, Henrik U Andersen, Tarunveer S Ahluwalia, Peter Rossing, Dídac Mauricio, Magnus T Jensen and Núria Alonso
    Citation: Cardiovascular Diabetology 2022 21:257
    Content type: Research Published on:

  12. The triglyceride–glucose (TyG) index is known as a reliable alternative marker of insulin resistance (IR), which has been regarded as a predictor of cardiovascular disease (CVD). However, whether TyG index can...

    Authors: Li Liu, Zhenguo Wu, Yifan Zhuang, Yerui Zhang, Huiliang Cui, Fanghong Lu, Jie Peng and Jianmin Yang
    Citation: Cardiovascular Diabetology 2022 21:256
    Content type: Research Published on:

  13. Individuals diagnosed with and treated for type 1 diabetes (T1D) have increased risk of micro- and macrovascular disease and excess mortality. Improving cardiovascular (CV) risk factors in individuals with T1D...

    Authors: Hanan Amadid, Kim Katrine Bjerring Clemmensen, Dorte Vistisen, Frederik Persson and Marit Eika Jørgensen
    Citation: Cardiovascular Diabetology 2022 21:255
    Content type: Research Published on:

  14. Evidence regarding thyroid-stimulating hormone (TSH) levels within the normal range and mortality in adults with diabetes is scarce. This study aimed to identify the association between TSH levels and cardiova...

    Authors: Ping Zhu, Guojuan Lao, Chuping Chen, Lihui Luo, Jing Gu and Jianmin Ran
    Citation: Cardiovascular Diabetology 2022 21:254
    Content type: Research Published on:

  15. Galectins are β-galactoside-binding proteins that bind and crosslink molecules via their sugar moieties, forming signaling and adhesion networks involved in cellular communication, differentiation, migration, ...

    Authors: Adel Abo Mansour, Franziska Krautter, Zhaogong Zhi, Asif Jilani Iqbal and Carlota Recio
    Citation: Cardiovascular Diabetology 2022 21:253
    Content type: Review Published on:

  16. Although type 2 diabetes mellitus (T2DM) and coronary artery disease (CAD) share many common pathological and physiological characteristics, there are few studies assessing the predictive capacity of novel bio...

    Authors: Yanhong Chen, Yu Fu, Shixin Wang, Pengsheng Chen, Yunfeng Pei, Jiao Zhang, Rui Zhang, Guoping Niu, Feng Gu and Xiaoli Li
    Citation: Cardiovascular Diabetology 2022 21:252
    Content type: Research Published on:

  17. It is unclear whether mental disorders are an independent risk factor for atrial fibrillation (AF) in patients with diabetes. We aimed to investigate whether patients with diabetes who have mental disorders ha...

    Authors: Nan Young Bae, So-Ryoung Lee, Eue-Keun Choi, Hyun Jin Ahn, Hyo-Jeong Ahn, Soonil Kwon, Kyung-Do Han, Kyu-Na Lee, Seil Oh and Gregory Y. H. Lip
    Citation: Cardiovascular Diabetology 2022 21:251
    Content type: Research Published on:

  18. Triglyceride-glucose (TyG) index is a simple and reliable surrogate marker of insulin resistance. Elevated TyG index was related to stroke recurrence. This study aimed to explore the associations between TyG i...

    Authors: Li Wu, Jinmao Zhu, Chenghao Li, Juehua Zhu, Zheng Dai and Yongjun Jiang
    Citation: Cardiovascular Diabetology 2022 21:250
    Content type: Research Published on:

  19. Pleiotropic effects have been implicated in clinical benefits of ticagrelor compared to thienopyridine P2Y12 antagonists. There are conflicting data regarding effects of ticagrelor vs. thienopyridine P2Y12 blocke...

    Authors: Bernadeta Chyrchel, Olga Kruszelnicka and Andrzej Surdacki
    Citation: Cardiovascular Diabetology 2022 21:249
    Content type: Research Published on:

  20. The reno-protective effect of second-line treatments in type 2 diabetes has been assessed by clinical trials but generalizability to routine clinical practice is still uncertain. We aimed to assess the effecti...

    Authors: Sukanya Siriyotha, Thitiya Lukkunaprasit, Panu Looareesuwan, Hataikarn Nimitphong, Gareth J. McKay, John Attia and Ammarin Thakkinstian
    Citation: Cardiovascular Diabetology 2022 21:248
    Content type: Research Published on:

  21. Cardiovascular risk and body-weight management are both emerging challenges of type 1 diabetes care. We evaluated the association between intraindividual variability of body-weight and risk of cardiovascular e...

    Authors: Iulia Petria, Samuel Albuquerque, Gaël Varoquaux, Jill-Jênn Vie, Nicolas Venteclef, Kamel Mohammedi, Ronan Roussel, Marion Camoin, Gianluca Perseghin, Gilberto Velho and Louis Potier
    Citation: Cardiovascular Diabetology 2022 21:247
    Content type: Research Published on:

  22. Diabetes Mellitus (DM) affects a third of patients with symptomatic severe aortic valve stenosis undergoing transcatheter aortic valve implantation (TAVI). DM is a well-known risk factor for cardiac surgery, b...

    Authors: Astrid C. van Nieuwkerk, Raquel B. Santos, Roberto Blanco Mata, Didier Tchétché, Fabio S. de Brito Jr, Marco Barbanti, Ran Kornowski, Azeem Latib, Augusto D’Onofrio, Flavio Ribichini, Jan Baan, Juan Oteo-Dominguez, Nicolas Dumonteil, Alexandre Abizaid, Samantha Sartori, Paola D’Errigo…
    Citation: Cardiovascular Diabetology 2022 21:246
    Content type: Research Published on:

  23. Hypertriglyceridemia is an important feature of dyslipidemia in type 1 and type 2 diabetic patients and associated with the development of atherosclerotic cardiovascular disease. Recently, variability of lipid...

    Authors: Sung Min Koh, Se Hwa Chung, Yun Jin Yum, Se Jun Park, Hyung Joon Joo, Yong-Hyun Kim and Eung Ju Kim
    Citation: Cardiovascular Diabetology 2022 21:245
    Content type: Research Published on:

  24. Carotid plaque and triglyceride-glucose (TyG) index are associated with insulin resistance. However, a highly debated question is whether there is an association between the TyG index and carotid plaque incide...

    Authors: Yichi Zhang, Zhuchao Wu, Xiaona Li, Jingkai Wei, Qun Zhang and Jianming Wang
    Citation: Cardiovascular Diabetology 2022 21:244
    Content type: Research Published on:

  25. The effect of diabetes mellitus (DM) on the long-term outcomes of coronary artery bypass graft (CABG) remained debatable and various strategies exist for CABG; hence, clarifying the effects of DM on CABG outco...

    Authors: Ilkun Park, Kuk Bin Choi, Joong Hyun Ahn, Wook Sung Kim, Young Tak Lee and Dong Seop Jeong
    Citation: Cardiovascular Diabetology 2022 21:243
    Content type: Research Published on:

  26. Several randomized controlled trials have demonstrated the benefits of glucagon-like peptide-1 receptor agonists (GLP-1RAs) on ischemic stroke in patients with diabetes. In this review, we summarize and discus...

    Authors: Bruno Vergès, Victor Aboyans, Denis Angoulvant, Pierre Boutouyrie, Bertrand Cariou, Fabien Hyafil, Kamel Mohammedi and Pierre Amarenco
    Citation: Cardiovascular Diabetology 2022 21:242
    Content type: Review Published on:

  27. Circulating fibrinogen-to-albumin ratio (FAR) has been proposed as a novel inflammatory biomarker and a cardiovascular disease risk predictor. However, its prognostic value in patients with acute decompensated...

    Authors: Rong Huang, Qing Dai, Lei Chang, Ziyan Wang, Jianzhou Chen, Rong Gu, Hongyan Zheng, Lei Hu, Biao Xu and Lian Wang
    Citation: Cardiovascular Diabetology 2022 21:241
    Content type: Research Published on:

  28. Nonalcoholic fatty liver disease is associated with an increased cardiovascular disease (CVD) risk, although the exact mechanism(s) are less clear. Moreover, the relationship between newly redefined metabolic-...

    Authors: Karolina Drożdż, Katarzyna Nabrdalik, Hanna Kwiendacz, Mirela Hendel, Anna Olejarz, Andrzej Tomasik, Wojciech Bartman, Jakub Nalepa, Janusz Gumprecht and Gregory Y. H. Lip
    Citation: Cardiovascular Diabetology 2022 21:240
    Content type: Research Published on:

  29. The baseline coronary plaque burden is the most important factor for rapid plaque progression (RPP) in the coronary artery. However, data on the independent predictors of RPP in the absence of a baseline coron...

    Authors: Ki-Bum Won, Byoung Kwon Lee, Fay Y. Lin, Martin Hadamitzky, Yong-Jin Kim, Ji Min Sung, Edoardo Conte, Daniele Andreini, Gianluca Pontone, Matthew J. Budoff, Ilan Gottlieb, Eun Ju Chun, Filippo Cademartiri, Erica Maffei, Hugo Marques, Pedro de Araújo Gonçalves…
    Citation: Cardiovascular Diabetology 2022 21:239
    Content type: Research Published on:

  30. Previous studies reported that there was right ventricular (RV) systolic dysfunction in patients with hypertension. The aim of this study was to evaluate the impact of type 2 diabetes mellitus (T2DM) on RV sys...

    Authors: Xue-Ming Li, Wei-Feng Yan, Li Jiang, Ke Shi, Yan Ren, Pei-Lun Han, Li-Qing Peng, Ying-Kun Guo and Zhi-Gang Yang
    Citation: Cardiovascular Diabetology 2022 21:238
    Content type: Research Published on:

  31. Optimal treatment strategies for patients with heart failure with preserved ejection fraction (HFpEF) remain uncertain. The goal of this study was to compare the treatment effects of different therapeutic agen...

    Authors: Yaowang Lin, Zhigang Cai, Jie Yuan, Huadong Liu, Xinli Pang, Qiuling Chen, Xinzheng Tang, Qingshan Geng and Shaohong Dong
    Citation: Cardiovascular Diabetology 2022 21:237
    Content type: Research Published on:

  32. Even though hyperglycemia is a well-known cardiovascular risk factor, the absolute risk of cardiovascular events varies to a great extent within each glycemic category. The aim of this study is to evaluate whe...

    Authors: Stefano Ciardullo, Federico Rea, Rosa Cannistraci, Emanuele Muraca, Silvia Perra, Francesca Zerbini, Andrea Mortara and Gianluca Perseghin
    Citation: Cardiovascular Diabetology 2022 21:236
    Content type: Research Published on:

  33. Nephropathy in Diabetes type 2 (NID-2) study is an open-label cluster randomized clinical trial that demonstrated that multifactorial intensive treatment reduces Major Adverse Cardiac Events (MACEs) and overal...

    Authors: Ferdinando Carlo Sasso, Vittorio Simeon, Raffaele Galiero, Alfredo Caturano, Luca De Nicola, Paolo Chiodini, Luca Rinaldi, Teresa Salvatore, Miriam Lettieri, Riccardo Nevola, Celestino Sardu, Giovanni Docimo, Giuseppe Loffredo, Raffaele Marfella, Luigi Elio Adinolfi and Roberto Minutolo
    Citation: Cardiovascular Diabetology 2022 21:235
    Content type: Research Published on:

  34. Bioactive lipids play an important role in insulin secretion and sensitivity, contributing to the pathophysiology of type 2 diabetes (T2D). This study aimed to identify novel lipid species associated with inci...

    Authors: Junda Zhong, Chloe Y. Y. Cheung, Xiuli Su, Chi-Ho Lee, Yi Ru, Carol H. Y. Fong, Yan Liu, Cynthia K. Y. Cheung, Karen S. L. Lam, Zongwei Cai and Aimin Xu
    Citation: Cardiovascular Diabetology 2022 21:234
    Content type: Research Published on:

  35. The prognostic value of common and frequently associated diabetic microvascular complications (MVC), namely chronic kidney disease (CKD), cardiac autonomic neuropathy (CAN), peripheral neuropathy (DPN), and re...

    Authors: Luca Sacchetta, Martina Chiriacò, Lorenzo Nesti, Simone Leonetti, Giovanna Forotti, Andrea Natali, Anna Solini and Domenico Tricò
    Citation: Cardiovascular Diabetology 2022 21:233
    Content type: Research Published on:

  36. To evaluate the cardiovascular and renal benefits of finerenone, sodium-glucose cotransporter-2 inhibitors (SGLT2i) and glucagonlike peptide-1 receptor agonists (GLP-1 RA) in patients with Type 2 Diabetes Mell...

    Authors: Yaofu Zhang, Li Jiang, Junheng Wang, Tongxin Wang, Chieh Chien, Weijun Huang, Xiaozhe Fu, Yonghua Xiao, Qiang Fu, Shidong Wang and Jinxi Zhao
    Citation: Cardiovascular Diabetology 2022 21:232
    Content type: Research Published on:

  37. Circulating thrombospondin-2 (TSP2) levels were associated with the development of heart failure (HF) in recent studies. However, these studies included only a minority of patients with type 2 diabetes, which ...

    Authors: CH Lee, MZ Wu, DTW Lui, CHY Fong, QW Ren, SY Yu, MMA Yuen, WS Chow, JY Huang, A Xu, KH Yiu and KSL Lam
    Citation: Cardiovascular Diabetology 2022 21:231
    Content type: Research Published on:

  38. Reduced lung function and adverse health outcomes are often observed. This study characterizes genetic susceptibility for reduced lung function and risk of developing a range of adverse health outcomes.

    Authors: Suneela Zaigham, Isabel Gonçalves, Regeneron Genetics Center, Gunnar Engström and Jiangming Sun
    Citation: Cardiovascular Diabetology 2022 21:230
    Content type: Research Published on:

  39. The relationship between triglyceride-glucose (TyG) index, an emerging marker of insulin resistance, and the risk of incident heart failure (HF) was unclear. This study thus aimed to investigate this relations...

    Authors: Xintao Li, Jeffrey Shi Kai Chan, Bo Guan, Shi Peng, Xiaoyu Wu, Xiaofeng Lu, Jiandong Zhou, Jeremy Man Ho Hui, Yan Hiu Athena Lee, Danish Iltaf Satti, Shek Long Tsang, Shouling Wu, Songwen Chen, Gary Tse and Shaowen Liu
    Citation: Cardiovascular Diabetology 2022 21:229
    Content type: Research Published on:

  40. Elevated remnant cholesterol (remnant-C) is considered a risk factor for cardiovascular disease (CVD); however, whether this notion applies to the East Asian population with type 2 diabetes (T2D) has not been ...

    Authors: Ji Hye Huh, Kyung-do Han, Yun Kyung Cho, Eun Roh, Jun Goo Kang, Seong Jin Lee and Sung-Hee Ihm
    Citation: Cardiovascular Diabetology 2022 21:228
    Content type: Research Published on:

  41. We aimed to investigate the gender difference in the association between changes in metabolic syndrome (MetS) and its components with the risk of cardiovascular disease (CVD) and coronary heart disease (CHD) a...

    Authors: Azra Ramezankhani, Fereidoun Azizi and Farzad Hadaegh
    Citation: Cardiovascular Diabetology 2022 21:227
    Content type: Research Published on:

  42. The triglyceride glucose (TyG) index, which is a new surrogate indicator of insulin resistance (IR), is thought to be associated with many diseases, such as cardiovascular disease, but its relationship with ce...

    Authors: Feifei Yan, Shoumeng Yan, Jing Wang, Yani Cui, Feinan Chen, Fang Fang and Weiwei Cui
    Citation: Cardiovascular Diabetology 2022 21:226
    Content type: Review Published on:

  43. Waist circumference (WC), visceral adiposity index (VAI), lipid accumulation product (LAP), and Chinese visceral adiposity index (CVAI) are considered surrogate indicators of abdominal fat deposition, but the ...

    Authors: Tingting Qiao, Tao Luo, Hualian Pei, Bahegu Yimingniyazi, Dilihumaer Aili, Aliya Aimudula, Hui Zhao, Huanwen Zhang, Jianghong Dai and Duolao Wang
    Citation: Cardiovascular Diabetology 2022 21:225
    Content type: Research Published on:

  44. Authors: Jinchun Wu, Tao Liu, Shaobo Shi, Zhixing Fan, Roddy Hiram, Feng Xiong, Bo Cui, Xiaoling Su, Rong Chang, Wei Zhang, Min Yan, Yanhong Tang, He Huang, Gang Wu and Congxin Huang
    Citation: Cardiovascular Diabetology 2022 21:224
    Content type: Correction Published on:

    The original article was published in Cardiovascular Diabetology 2022 21:197

  45. Diabetes mellitus (DM) is associated with an increased mortality risk in patients hospitalized with acute myocardial infarction (AMI); however, no studies have investigated the impact of the duration of DM on ...

    Authors: Marta Baviera, Stefano Genovese, Pierluca Colacioppo, Nicola Cosentino, Andreana Foresta, Mauro Tettamanti, Ida Fortino, Maria Carla Roncaglioni and Giancarlo Marenzi
    Citation: Cardiovascular Diabetology 2022 21:223
    Content type: Research Published on:

  46. Coronary microvascular dysfunction (CMD) is common and is associated with unfavorable cardiovascular events in patients with diabetes mellitus (DM). Coronary angiography-derived index of microcirculatory resis...

    Authors: Wen Zhang, Shekhar Singh, Lu Liu, Abdul-Quddus Mohammed, Guoqing Yin, Siling Xu, Xian Lv, Tingting Shi, Cailin Feng, Rong Jiang, Ayman A. Mohammed, Redhwan M. Mareai, Yawei Xu, Xuejing Yu, Fuad A. Abdu and Wenliang Che
    Citation: Cardiovascular Diabetology 2022 21:222
    Content type: Research Published on:

  47. Previous studies showed that gestational diabetes mellitus (GDM) can be a risk factor for subsequent atherosclerotic cardiovascular disease. However, there is a paucity of information regarding diverse cardiov...

    Authors: Seung Mi Lee, Manu Shivakumar, Ji Won Park, Young Mi Jung, Eun Kyung Choe, Soo Heon Kwak, Sohee Oh, Joong Shin Park, Jong Kwan Jun, Dokyoon Kim and Jae-Seung Yun
    Citation: Cardiovascular Diabetology 2022 21:221
    Content type: Research Published on:

  48. Diabetes mellitus (DM) and cardiovascular diseases often co-exist. Today, percutaneous coronary intervention (PCI) is the preferred revascularization procedure for majority of patients with coronary artery dis...

    Authors: Hong Wang, Xiaoya Xie, Quannan Zu, Ming Lu, Rongfa Chen, Zhiren Yang and Yongqiang Gao
    Citation: Cardiovascular Diabetology 2022 21:220
    Content type: Research Published on:

  49. Authors: Jesus F. Garcia‑Gavilan, Margery A. Connelly, Nancy Babio, Christos S. Mantzoros, Emilio Ros and Jordi Salas‑Salvado
    Citation: Cardiovascular Diabetology 2022 21:219
    Content type: Correction Published on:

    The original article was published in Cardiovascular Diabetology 2022 21:189

  50. Few studies have examined the association between hypoglycemic episodes among people with type 2 diabetes (T2DM) at the time of hospitalization for heart failure (HF) and cardiovascular outcomes.

    Authors: Seon-Ah Cha, Jae-Seung Yun, Gee-Hee Kim and Yu-Bae Ahn
    Citation: Cardiovascular Diabetology 2022 21:218
    Content type: Research Published on:
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