Cardiovascular Diabetology is affiliated with Sackler Faculty of Medicine, Tel-Aviv University
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Page 5 of 53
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Citation: Cardiovascular Diabetology 2022 21:224
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Diabetes mellitus duration and mortality in patients hospitalized with acute myocardial infarction
Diabetes mellitus (DM) is associated with an increased mortality risk in patients hospitalized with acute myocardial infarction (AMI); however, no studies have investigated the impact of the duration of DM on ...
Citation: Cardiovascular Diabetology 2022 21:223 -
Prognostic value of coronary microvascular dysfunction assessed by coronary angiography-derived index of microcirculatory resistance in diabetic patients with chronic coronary syndrome
Coronary microvascular dysfunction (CMD) is common and is associated with unfavorable cardiovascular events in patients with diabetes mellitus (DM). Coronary angiography-derived index of microcirculatory resis...
Citation: Cardiovascular Diabetology 2022 21:222 -
Long-term cardiovascular outcomes of gestational diabetes mellitus: a prospective UK Biobank study
Previous studies showed that gestational diabetes mellitus (GDM) can be a risk factor for subsequent atherosclerotic cardiovascular disease. However, there is a paucity of information regarding diverse cardiov...
Citation: Cardiovascular Diabetology 2022 21:221 -
One-year outcomes of polymer-free amphilimus-eluting stents versus durable polymer zotarolimus-eluting stents in patients with diabetes mellitus: a meta-analysis
Diabetes mellitus (DM) and cardiovascular diseases often co-exist. Today, percutaneous coronary intervention (PCI) is the preferred revascularization procedure for majority of patients with coronary artery dis...
Citation: Cardiovascular Diabetology 2022 21:220 -
Correction: Nut consumption is associated with a shift of the NMR lipoprotein subfraction profile to a less atherogenic pattern among older individuals at high CVD risk
Citation: Cardiovascular Diabetology 2022 21:219 -
Impact of hypoglycemia at the time of hospitalization for heart failure from emergency department on major adverse cardiovascular events in patients with and without type 2 diabetes
Few studies have examined the association between hypoglycemic episodes among people with type 2 diabetes (T2DM) at the time of hospitalization for heart failure (HF) and cardiovascular outcomes.
Citation: Cardiovascular Diabetology 2022 21:218 -
Association of stress hyperglycemia ratio and in-hospital mortality in patients with coronary artery disease: insights from a large cohort study
Stress hyperglycemia is strongly associated with poor clinical outcomes in patients with acute coronary syndrome (ACS). Recently, the stress hyperglycemia ratio (SHR) has been proposed to represent relative hy...
Citation: Cardiovascular Diabetology 2022 21:217 -
The association between macrovascular complications and intensive care admission, invasive mechanical ventilation, and mortality in people with diabetes hospitalized for coronavirus disease-2019 (COVID-19)
It is not clear whether pre-existing macrovascular complications (ischemic heart disease, stroke or peripheral artery disease) are associated with health outcomes in people with diabetes mellitus hospitalized ...
Citation: Cardiovascular Diabetology 2022 21:216 -
TyGIS: improved triglyceride-glucose index for the assessment of insulin sensitivity during pregnancy
The triglyceride-glucose index (TyG) has been proposed as a surrogate marker of insulin resistance, which is a typical trait of pregnancy. However, very few studies analyzed TyG performance as marker of insuli...
Citation: Cardiovascular Diabetology 2022 21:215 -
Serum high mobility group box-1 levels associated with cardiovascular events after lower extremity revascularization: a prospective study of a diabetic population
Peripheral arterial disease (PAD) is one of the most disabling cardiovascular complications of type 2 diabetes mellitus and is indeed associated with a high risk of cardiovascular and limb adverse events. High...
Citation: Cardiovascular Diabetology 2022 21:214 -
Response of circulating metabolites to an oral glucose challenge and risk of cardiovascular disease and mortality in the community
New biomarkers to identify cardiovascular disease (CVD) risk earlier in its course are needed to enable targeted approaches for primordial prevention. We evaluated whether intraindividual changes in blood meta...
Citation: Cardiovascular Diabetology 2022 21:213 -
Novel lipid indicators and the risk of type 2 diabetes mellitus among Chinese hypertensive patients: findings from the Guangzhou Heart Study
Data are limited on whether several easily measured indices are independent predictors of type 2 diabetes mellitus (T2DM) in hypertensive patients. This study aimed to assess the association of hypertriglyceri...
Citation: Cardiovascular Diabetology 2022 21:212 -
Microvascular complications identify a specific coronary atherosclerotic phenotype in patients with type 2 diabetes mellitus
Patients with type 2 diabetes mellitus (T2DM) are considered as a homogeneous cohort of patients. However, the specific role of diabetic microvascular complications (DMC), in determining the features of corona...
Citation: Cardiovascular Diabetology 2022 21:211 -
Non-obese NAFLD had no better cardio-metabolic risk profile than obese NAFLD in type 2 diabetic patients
Non-obese non-alcoholic fatty liver disease (NAFLD) has been reported to share clinical outcomes with its obese counterpart in the general population. However, conflicting results have been observed regarding ...
Citation: Cardiovascular Diabetology 2022 21:210 -
Fatty liver index as a predictor for incident type 2 diabetes in community-dwelling adults: longitudinal findings over 12 years
Diagnosing fatty liver and identifying disease status are important for fatty liver related-diseases prevention. The fatty liver index (FLI), which can be easily available in clinical practice, can be very use...
Citation: Cardiovascular Diabetology 2022 21:209 -
Association between metabolically healthy obesity and risk of atrial fibrillation: taking physical activity into consideration
The modification of physical activity (PA) on the metabolic status in relation to atrial fibrillation (AF) in obesity remains unknown. We aimed to investigate the independent and joint associations of metaboli...
Citation: Cardiovascular Diabetology 2022 21:208 -
Association of α-klotho with subclinical carotid atherosclerosis in subjects with type 1 diabetes mellitus
Compelling evidence suggests that the fibroblast growth factor 23 (FGF23) / α-klotho axis is impaired in subjects with diabetes mellitus. We examined the relationship between parameters related to calcium/phos...
Citation: Cardiovascular Diabetology 2022 21:207 -
Leukocyte telomere length, allelic variations in related genes and risk of coronary heart disease in people with long-standing type 1 diabetes
Type 1 diabetes is associated with accelerated vascular aging and advanced atherosclerosis resulting in increased rates of cardiovascular disease and premature death. We evaluated associations between Leukocyt...
Citation: Cardiovascular Diabetology 2022 21:206 -
Neuregulin-4 attenuates diabetic cardiomyopathy by regulating autophagy via the AMPK/mTOR signalling pathway
Diabetic cardiomyopathy is characterized by left ventricle dysfunction, cardiomyocyte apoptosis, and interstitial fibrosis and is a serious complication of diabetes mellitus (DM). Autophagy is a mechanism that...
Citation: Cardiovascular Diabetology 2022 21:205 -
Association between triglyceride glucose index and atherosclerotic plaques and Burden: findings from a community-based study
Insulin resistance is an important cause of cardiovascular events and cerebral infarction development. We aimed to investigate the association of the triglyceride glucose (TyG) index with atherosclerotic burde...
Citation: Cardiovascular Diabetology 2022 21:204 -
Real-world characteristics, modern antidiabetic treatment patterns, and comorbidities of patients with type 2 diabetes in central and Eastern Europe: retrospective cross-sectional and longitudinal evaluations in the CORDIALLY® study
Guidelines from 2016 onwards recommend early use of SGLT2i or GLP-1 RA for patients with type 2 diabetes (T2D) and cardiovascular disease (CVD), to reduce CV events and mortality. Many eligible patients are no...
Citation: Cardiovascular Diabetology 2022 21:203 -
The severity and duration of Hypoglycemia affect platelet-derived protein responses in Caucasians
Severe hypoglycemia is associated with increased cardiovascular death risk, and platelet responses to hypoglycemia (hypo) have been described. However, the impact of deep transient hypo (deep-hypo) versus prol...
Citation: Cardiovascular Diabetology 2022 21:202 -
The bidirectional association of C-peptide with cardiovascular risk in nondiabetic adults and patients with newly diagnosed type 2 diabetes mellitus: a retrospective cohort study
Recent literature reported the biological role of C-peptide, but this role is still controversial and unclear. The primary aim of this study was to investigate associations between C-peptide and cardiovascular...
Citation: Cardiovascular Diabetology 2022 21:201 -
Effects of dulaglutide on endothelial progenitor cells and arterial elasticity in patients with type 2 diabetes mellitus
Randomised controlled trial showed that dulaglutide can reduce the risk of atherosclerotic cardiovascular disease (ASCVD) in patients with type 2 diabetes mellitus (T2DM), but the underlying mechanisms remain ...
Citation: Cardiovascular Diabetology 2022 21:200 -
Association between healthy lifestyle and the occurrence of cardiometabolic multimorbidity in hypertensive patients: a prospective cohort study of UK Biobank
Cardiometabolic multimorbidity (CMM) is becoming increasingly common in patients with hypertension, and it is well established that healthy lifestyle plays a key role in the prevention of hypertension. However...
Citation: Cardiovascular Diabetology 2022 21:199 -
Sex-related disparities in the incidence and outcomes of infective endocarditis according to type 2 diabetes mellitus status in Spain, 2016–2020
We performed a study to assess sex-differences in incidence (2016–2020), clinical characteristics, use of therapeutic procedures, and in-hospital outcomes in patients with infective endocarditis (IE) according...
Citation: Cardiovascular Diabetology 2022 21:198 -
Dapagliflozin reduces the vulnerability of rats with pulmonary arterial hypertension-induced right heart failure to ventricular arrhythmia by restoring calcium handling
Malignant ventricular arrhythmia (VA) is a major contributor to sudden cardiac death (SCD) in patients with pulmonary arterial hypertension (PAH)-induced right heart failure (RHF). Recently, dapagliflozin (DAP...
Citation: Cardiovascular Diabetology 2022 21:197 -
Results of a prospective observational study of autologous peripheral blood mononuclear cell therapy for no-option critical limb-threatening ischemia and severe diabetic foot ulcers
Cell therapy with autologous peripheral blood mononuclear cells (PB-MNCs) may help restore limb perfusion in patients with diabetes mellitus and critical limb-threatening ischemia (CLTI) deemed not eligible fo...
Citation: Cardiovascular Diabetology 2022 21:196 -
Plasma mannose as a novel marker of myocardial infarction across different glycaemic states: a case control study
Plasma mannose, an emerging novel biomarker of insulin resistance, is associated with both diabetes mellitus and coronary atherosclerosis, but the relationship between mannose concentrations and myocardial inf...
Citation: Cardiovascular Diabetology 2022 21:195 -
Initiation of the SGLT2 inhibitor canagliflozin to prevent kidney and heart failure outcomes guided by HbA1c, albuminuria, and predicted risk of kidney failure
Sodium glucose co-transporter-2 (SGLT2) inhibitors reduce the risk of kidney and heart failure events independent of glycemic effects. We assessed whether initiation of the SGLT2 inhibitor canagliflozin guided...
Citation: Cardiovascular Diabetology 2022 21:194 -
Incremental prognostic value of triglyceride glucose index additional to coronary artery calcium score in asymptomatic low-risk population
The triglyceride glucose (TyG) index has been suggested as a reliable surrogate marker of insulin resistance which is a substantial risk factor for atherosclerotic cardiovascular disease (ASCVD). Several recen...
Citation: Cardiovascular Diabetology 2022 21:193 -
Evaluating the impact of glucokinase activation on risk of cardiovascular disease: a Mendelian randomisation analysis
Glucokinase activators (GKAs) are an emerging class of glucose lowering drugs that activate the glucose-sensing enzyme glucokinase (GK). Pending formal cardiovascular outcome trials, we applied two-sample Mend...
Citation: Cardiovascular Diabetology 2022 21:192 -
Eliminating exogenous insulin therapy in patients with type 2 diabetes by duodenal ablation and GLP-1RA decreases risk scores for cardiovascular events
Duodenal Mucosal Resurfacing (DMR) is an endoscopic ablation technique aimed at improving glycaemia and metabolic health in patients with type 2 diabetes mellitus (T2DM). DMR has an insulin sensitizing effect ...
Citation: Cardiovascular Diabetology 2022 21:191 -
Proteomics of fibrin amyloid microclots in long COVID/post-acute sequelae of COVID-19 (PASC) shows many entrapped pro-inflammatory molecules that may also contribute to a failed fibrinolytic system
Post-acute sequelae of COVID-19 (PASC), also now known as long COVID, has become a major global health and economic burden. Previously, we provided evidence that there is a significant insoluble fibrin amyloid...
Citation: Cardiovascular Diabetology 2022 21:190 -
Nut consumption is associated with a shift of the NMR lipoprotein subfraction profile to a less atherogenic pattern among older individuals at high CVD risk
Scientific evidence has accumulated on the beneficial effects of nut consumption on cardiovascular risk and cholesterol reduction, but few studies have examined the effects of nuts on advanced measures of lipo...
Citation: Cardiovascular Diabetology 2022 21:189 -
Immune-inflammatory biomarkers and the risk of cardiac injury in COVID-19 patients with diabetes: a retrospective cohort study
To determine the risk-assessment role of the immune-inflammatory biomarkers on myocardial damage in COVID-19 patients with diabetes mellitus (DM).
Citation: Cardiovascular Diabetology 2022 21:188 -
Association between triglyceride glucose index, coronary artery calcification and multivessel coronary disease in Chinese patients with acute coronary syndrome
Multivessel coronary disease (MVCD) is the common type of coronary artery disease in acute coronary syndrome (ACS). Coronary artery calcification (CAC) has been confirmed the strong predictor of major adverse ...
Citation: Cardiovascular Diabetology 2022 21:187 -
Effect of dapagliflozin on the prognosis of patients with acute myocardial infarction undergoing percutaneous coronary intervention
The effect of dapagliflozin (DAPA) on the prognosis of patients with acute myocardial infarction (AMI) is unclear. The present study was conducted to evaluate the association between DAPA administration and ad...
Citation: Cardiovascular Diabetology 2022 21:186 -
CCL7 as a novel inflammatory mediator in cardiovascular disease, diabetes mellitus, and kidney disease
Chemokines are key components in the pathology of chronic diseases. Chemokine CC motif ligand 7 (CCL7) is believed to be associated with cardiovascular disease, diabetes mellitus, and kidney disease. CCL7 may ...
Citation: Cardiovascular Diabetology 2022 21:185 -
Professor Alexander Tenenbaum: obituary
Citation: Cardiovascular Diabetology 2022 21:184 -
Time course of the triglyceride glucose index accumulation with the risk of cardiovascular disease and all-cause mortality
Future risk of cardiovascular disease (CVD) and mortality is associated with cumulative amount TyG index (cumTyG) exposure, while whether time course of TyG accumulation modulates the risk remains unclear. Thi...
Citation: Cardiovascular Diabetology 2022 21:183 -
Risk prediction models for incident type 2 diabetes in Chinese people with intermediate hyperglycemia: a systematic literature review and external validation study
People with intermediate hyperglycemia (IH), including impaired fasting glucose and/or impaired glucose tolerance, are at higher risk of developing type 2 diabetes (T2D) than those with normoglycemia. We aimed...
Citation: Cardiovascular Diabetology 2022 21:182 -
Effect of empagliflozin on left ventricular contractility and peak oxygen uptake in subjects with type 2 diabetes without heart disease: results of the EMPA-HEART trial
The mechanism through which sodium-glucose cotransporter 2 inhibitors (SGLT2i) prevent the incidence of heart failure and/or affect cardiac structure and function remains unclear.
Citation: Cardiovascular Diabetology 2022 21:181 -
Prognostic value of soluble ST2, high-sensitivity cardiac troponin, and NT-proBNP in type 2 diabetes: a 15-year retrospective study
Patients with type 2 diabetes (T2DM) present an increased risk of cardiovascular (CV) disease and excess CV-related mortality. Beyond the established role of brain natriuretic peptide (BNP) and cardiac troponi...
Citation: Cardiovascular Diabetology 2022 21:180 -
Cardiovascular and metabolic morbidity in women with previous gestational diabetes mellitus: a nationwide register-based cohort study
Gestational diabetes mellitus (GDM) is associated with adverse pregnancy outcomes and has maternal health implications reaching beyond the perinatal period. We aimed to investigate the incidence and severity o...
Citation: Cardiovascular Diabetology 2022 21:179 -
Higher pulse wave velocity in young adult offspring of mothers with type 1 diabetes: a case–control study
Offspring of mothers with type 1 diabetes have an increased risk for acquiring early onset cardiovascular disease (CVD). Arterial stiffness, measured as pulse wave velocity (PWV), is a non-invasive biomarker f...
Citation: Cardiovascular Diabetology 2022 21:178 -
Long-term cardiovascular prognosis of patients with type 1 diabetes after myocardial infarction
To explore long-term cardiovascular prognosis after myocardial infarction (MI) among patients with type 1 diabetes.
Citation: Cardiovascular Diabetology 2022 21:177 -
Anti-obesity therapy for cardiovascular disease prevention: potential expected roles of glucagon-like peptide-1 receptor agonists
Obesity is characterized by visceral fat accumulation and various metabolic disturbances that cause metabolic syndrome and obesity-related cardiovascular diseases (ORCVDs). Hence, treatments targeting obesity ...
Citation: Cardiovascular Diabetology 2022 21:176 -
Revascularization outcomes in diabetic patients presenting with acute coronary syndrome with non-ST elevation
To compare the outcomes of diabetic patients hospitalized with non-ST elevation myocardial infarction (NSTEMI) or unstable angina (UA) referred for revascularization by either coronary artery bypass grafting (...
Citation: Cardiovascular Diabetology 2022 21:175
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