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  1. Recent large clinical trials have demonstrated cardiovascular benefits of similar overall magnitude for sodium–glucose cotransporter-2 inhibitor (SGLT-2i) and glucagon-like peptide-1 receptor agonist (GLP-1RA)...

    Authors: Minji Sohn, Johannes W. Dietrich, Michael A. Nauck and Soo Lim
    Citation: Cardiovascular Diabetology 2023 22:153
    Content type: Research Published on:

  2. This study aimed to investigate the impact of lipoprotein(a) [Lp(a)] levels on the prognosis of Chinese patients with ST-segment elevation myocardial infarction (STEMI), and to explore if the impact may differ...

    Authors: Nan Li, Jinying Zhou, Runzhen Chen, Xiaoxiao Zhao, Jiannan Li, Peng Zhou, Chen Liu, Yi Chen, Ying Wang, Li Song, Shaodi Yan, Hanjun Zhao and Hongbing Yan
    Citation: Cardiovascular Diabetology 2023 22:151
    Content type: Research Published on:

  3. The potential predictive significance of atherogenic index of plasma (AIP) for cardiovascular outcomes in patients with acute coronary syndrome (ACS) and who have undergone percutaneous coronary intervention (...

    Authors: Yue Wang, Shen Wang, Shuaifeng Sun, Fadong Li, Wenxin Zhao, Hongxia Yang and Xiaofan Wu
    Citation: Cardiovascular Diabetology 2023 22:150
    Content type: Research Published on:

  4. Elevated triglyceride-glucose (TyG) index and N-terminal pro-B-type natriuretic peptide (NT-proBNP) are independently associated with increased risk of major adverse cardio-cerebral events (MACCEs) in diabetic...

    Authors: Man Wang, Li Zhou, Wen Su, Wenxi Dang, Hongwei Li and Hui Chen
    Citation: Cardiovascular Diabetology 2023 22:149
    Content type: Research Published on:

  5. Diabetic foot is a significant cause of morbidity in diabetic patients, with a rate that is approximately twice that of patients without foot ulcers. “Metabolic memory” represents the epigenetic changes induce...

    Authors: Alessandro Del Cuore, Rosaria Maria Pipitone, Alessandra Casuccio, Marco Maria Mazzola, Maria Grazia Puleo, Gaetano Pacinella, Renata Riolo, Carlo Maida, Tiziana Di Chiara, Domenico Di Raimondo, Rossella Zito, Giulia Lupo, Luisa Agnello, Gabriele Di Maria, Marcello Ciaccio, Stefania Grimaudo…
    Citation: Cardiovascular Diabetology 2023 22:148
    Content type: Research Published on:

  6. Impaired kidney function and albuminuria are associated with increased risk of heart failure (HF) in patients with type 2 diabetes (T2D). We investigated whether rapid kidney function decline over time is an a...

    Authors: Carlos Roberto Bueno Junior, Arjola Bano, Yaling Tang, Xiuqin Sun, Alex Abate, Elizabeth Hall, Joanna Mitri, Mario Luca Morieri, Hetal Shah and Alessandro Doria
    Citation: Cardiovascular Diabetology 2023 22:131
    Content type: Research Published on:

  7. Type 2 diabetes is associated with an increased risk of developing cardiovascular events. Previous studies have reported that advanced glycation end products (AGEs) were related to cardiovascular events in typ...

    Authors: Tomoka Nakamura, Tetsuro Tsujimoto, Kazuki Yasuda, Kohjiro Ueki and Hiroshi Kajio
    Citation: Cardiovascular Diabetology 2023 22:147
    Content type: Research Published on:

  8. The occurrence and development of coronary heart disease (CHD) are closely linked to fluctuations in blood glucose levels. While the efficacy of intensified treatment guided by HbA1c levels remains uncertain f...

    Authors: Jingyang Chen, Dong Yin and Kefei Dou
    Citation: Cardiovascular Diabetology 2023 22:146
    Content type: Review Published on:

  10. The nuclear receptor corepressor 1 (NCOR1) plays an important role in the regulation of gene expression in immunometabolic conditions by connecting chromatin-modifying enzymes, coregulators and transcription f...

    Authors: Martin Geiger, Sara Oppi, Stefanie Nusser-Stein, Sarah Costantino, Shafeeq Ahmed Mohammed, Era Gorica, Joanne A. Hoogerland, Christian M. Matter, Ana T. Guillaumon, Frank Ruschitzka, Francesco Paneni, Maaike H. Oosterveer and Sokrates Stein
    Citation: Cardiovascular Diabetology 2023 22:144
    Content type: Research Published on:

  11. This study aimed to assess the long-term effects of tofogliflozin, a sodium-glucose cotransporter 2 (SGLT2) inhibitor, on atherosclerosis progression and major clinical parameters in patients with type 2 diabe...

    Authors: Naoto Katakami, Tomoya Mita, Hidenori Yoshii, Toshihiko Shiraiwa, Tetsuyuki Yasuda, Yosuke Okada, Akira Kurozumi, Masahiro Hatazaki, Hideaki Kaneto, Takeshi Osonoi, Tsunehiko Yamamoto, Nobuichi Kuribayashi, Kazuhisa Maeda, Hiroki Yokoyama, Keisuke Kosugi, Kentaro Ohtoshi…
    Citation: Cardiovascular Diabetology 2023 22:143
    Content type: Research Published on:

  12. Biomarker of insulin resistance, namely triglyceride-glucose index, is potentially useful in identifying critically ill patients at high risk of hospital death. However, the TyG index might have variations ove...

    Authors: Long Cheng, Feng Zhang, Wenjing Xue, Peng Yu, Xiaoyan Wang, Hairong Wang, Jun Wang, Tianyang Hu, Hui Gong and Li Lin
    Citation: Cardiovascular Diabetology 2023 22:142
    Content type: Research Published on:

  13. Metabolic Syndrome (MetS) is characterized by risk factors such as abdominal obesity, hypertriglyceridemia, low high-density lipoprotein cholesterol (HDL-C), hypertension, and hyperglycemia, which contribute t...

    Authors: Mengya Shi, Siyu Han, Kristin Klier, Gisela Fobo, Corinna Montrone, Shixiang Yu, Makoto Harada, Ann-Kristin Henning, Nele Friedrich, Martin Bahls, Marcus Dörr, Matthias Nauck, Henry Völzke, Georg Homuth, Hans J. Grabe, Cornelia Prehn…
    Citation: Cardiovascular Diabetology 2023 22:141
    Content type: Research Published on:

  14. Cardiovascular mortality and the impact of cardiac risk factors in advanced chronic kidney disease (CKD) remain poorly investigated. We examined the risk of cardiovascular mortality in patients with advanced C...

    Authors: Dea Haagensen Kofod, Nicholas Carlson, Ellen Freese Ballegaard, Thomas Peter Almdal, Christian Torp-Pedersen, Gunnar Gislason, Jesper Hastrup Svendsen, Bo Feldt-Rasmussen and Mads Hornum
    Citation: Cardiovascular Diabetology 2023 22:140
    Content type: Research Published on:

  15. An accurate prediction of survival prognosis is beneficial to guide clinical decision-making. This prospective study aimed to develop a model to predict one-year mortality among older patients with coronary ar...

    Authors: Yan Li, Lixun Guan, Chaoxue Ning, Pei Zhang, Yali Zhao, Qiong Liu, Ping Ping and Shihui Fu
    Citation: Cardiovascular Diabetology 2023 22:139
    Content type: Research Published on:

  16. The triglyceride-glucose (TyG) index was significantly associated with insulin resistance (IR). Several studies have validated the effect of TyG index on cerebrovascular disease. However, the value of TyG inde...

    Authors: Weimin Cai, Jun Xu, Xiao Wu, Zhuoyan Chen, Liuwei Zeng, Xian Song, Yuan Zeng and Fujun Yu
    Citation: Cardiovascular Diabetology 2023 22:138
    Content type: Research Published on:

  17. Visceral obesity is associated with high cardiovascular events risk in type 2 diabetes mellitus (T2DM). Whether normal-weight visceral obesity will pose a higher atherosclerotic cardiovascular disease (ASCVD) ...

    Authors: Jia Zheng, Ye Hu, Hanwen Xu, Yu Lei, Jieji Zhang, Qidong Zheng, Li Li, Weiping Tu, Riqiu Chen, Qiongyao Guo, Xunxiong Zang, Qiaoying You, Zhiyong Xu, Qiang Zhou and Xiaohong Wu
    Citation: Cardiovascular Diabetology 2023 22:137
    Content type: Research Published on:

  18. Lower-extremity endovascular revascularization (LER) is often required for diabetic patients with chronic limb threatening ischemia (CLTI). During the post-revascularization period patients may unpredictably e...

    Authors: Elisabetta Nardella, Federico Biscetti, Maria Margherita Rando, Andrea Leonardo Cecchini, Maria Anna Nicolazzi, Enrica Rossini, Flavia Angelini, Roberto Iezzi, Luis H. Eraso, Paul J. Dimuzio, Dario Pitocco, Massimo Massetti, Antonio Gasbarrini and Andrea Flex
    Citation: Cardiovascular Diabetology 2023 22:136
    Content type: Research Published on:

  19. The association of incident cardiometabolic multimorbidity (CMM) with mortality risk is rarely studied, and neither are the durations of cardiometabolic diseases (CMDs). Whether the association patterns of CMD...

    Authors: Yuting Han, Yizhen Hu, Canqing Yu, Dianjianyi Sun, Yuanjie Pang, Pei Pei, Ling Yang, Yiping Chen, Huaidong Du, Jingchao Liu, Dan Schmidt, Daniel Avery, Junshi Chen, Zhengming Chen, Liming Li and Jun Lv
    Citation: Cardiovascular Diabetology 2023 22:135
    Content type: Research Published on:

  21. The triglyceride–glucose (TyG) index has been proposed as a potential predictor of adverse prognosis of cardiovascular diseases (CVDs). However, its prognostic value in patients with coronary heart disease (CH...

    Authors: Yahui Liu, Binbin Zhu, Weicen Zhou, Yao Du, Datun Qi, Chenxu Wang, Qianqian Cheng, You Zhang, Shan Wang and Chuanyu Gao
    Citation: Cardiovascular Diabetology 2023 22:133
    Content type: Research Published on:

  22. Stroke has been found to be highly correlated with the triglyceride-glucose (TyG) index. The relation between the TyG index changes and stroke, however, has seldom been reported, and current researches mention...

    Authors: Yaoling Wu, Yongbiao Yang, Jinsheng Zhang, Shuo Liu and Weiduan Zhuang
    Citation: Cardiovascular Diabetology 2023 22:132
    Content type: Research Published on:

  23. The triglyceride-glucose (TyG) index has been recognized as being an alternative cardiometabolic biomarker for insulin resistance associated with the development and prognosis of cardiovascular disease (CVD). ...

    Authors: Haixu Yu, Liyuan Tao, Yan-Guang Li, Lincheng Yang, Dan Liu, Yang Wang, Xiaoyan Hao, Honghai He, Ying Che, Peng Wang, Wei Zhao and Wei Gao
    Citation: Cardiovascular Diabetology 2023 22:130
    Content type: Research Published on:

  24. Patients with prediabetes or diabetes are at increased risk of developing cardiovascular disease and adverse outcomes. First-line coronary computed tomography angiography (CTA) followed by selective use of pos...

    Authors: Matias Mäenpää, Iida Kujala, Esa Harjulahti, Iida Stenström, Wail Nammas, Juhani Knuuti, Antti Saraste and Teemu Maaniitty
    Citation: Cardiovascular Diabetology 2023 22:129
    Content type: Research Published on:

  25. Glucagon is thought to increase heart rate and contractility by stimulating glucagon receptors and increasing 3′,5′-cyclic adenosine monophosphate (cAMP) production in the myocardium. This has been confirmed i...

    Authors: Ramón Aranda-Domene, Esteban Orenes-Piñero, José María Arribas-Leal, Sergio Canovas-Lopez and Jesús Hernández-Cascales
    Citation: Cardiovascular Diabetology 2023 22:128
    Content type: Research Published on:

  26. Authors: Vittoria Favero, Carmen Aresta, Chiara Parazzoli, Elisa Cairoli, Cristina Eller-Vainicher, Serena Palmieri, Antonio Stefano Salcuni, Maura Arosio, Luca Persani, Alfredo Scillitani, Valentina Morelli and Iacopo Chiodini
    Citation: Cardiovascular Diabetology 2023 22:127
    Content type: Correction Published on:

    The original article was published in Cardiovascular Diabetology 2023 22:102

  27. In clinical trials enrolling patients with type 2 diabetes (T2D) at high cardiovascular risk, many glucagon-like peptide-1 receptor agonists (GLP-1 RAs) improved albuminuria status and possibly mitigated kidne...

    Authors: Meir Schechter, Cheli Melzer Cohen, Alisa Fishkin, Aliza Rozenberg, Ilan Yanuv, Dvora R. Sehtman-Shachar, Gabriel Chodick, Alice Clark, Trine J. Abrahamsen, Jack Lawson, Avraham Karasik and Ofri Mosenzon
    Citation: Cardiovascular Diabetology 2023 22:126
    Content type: Research Published on:

  28. The atherogenic index of plasma (AIP) is an important alternative metabolic biomarker of atherosclerosis and cardiovascular diseases. Nevertheless, the correlation between the AIP and carotid atherosclerosis i...

    Authors: Qin Huang, Zeyu Liu, Minping Wei, Qing Huang, Jie Feng, Zunjing Liu and Jian Xia
    Citation: Cardiovascular Diabetology 2023 22:125
    Content type: Research Published on:

    The Correction to this article has been published in Cardiovascular Diabetology 2023 22:246

  29. Atrial fibrillation (AF) and heart failure (HF) frequently coexist because of their similar pathological basis. However, whether sodium-glucose cotransporter 2 inhibitor (SGLT2i), a novel class of anti-HF medi...

    Authors: Xiaolan Ouyang, Jiafu Wang, Qian Chen, Long Peng, Suhua Li and Xixiang Tang
    Citation: Cardiovascular Diabetology 2023 22:124
    Content type: Review Published on:

  30. In this review, we summarise new insights into diagnostic approaches and treatment strategies for coronary artery disease (CAD) in patients with diabetes mellitus (DM). Despite the improvements in therapy, the...

    Authors: Tobias Michiel Hommels, Renicus Suffridus Hermanides, Enrico Fabris and Elvin Kedhi
    Citation: Cardiovascular Diabetology 2023 22:123
    Content type: Review Published on:

  31. Diabetes mellitus, a group of metabolic disorders characterized by high levels of blood glucose caused by insulin defect or impairment, is a major risk factor for cardiovascular diseases and related mortality....

    Authors: Gaia Spinetti, Martina Mutoli, Simona Greco, Federica Riccio, Soumaya Ben-Aicha, Franziska Kenneweg, Amela Jusic, David de Gonzalo-Calvo, Anne Yaël Nossent, Susana Novella, Georgios Kararigas, Thomas Thum, Costanza Emanueli, Yvan Devaux and Fabio Martelli
    Citation: Cardiovascular Diabetology 2023 22:122
    Content type: Review Published on:

  32. Pericoronary adipose tissue (PCAT) density is a biomarker of vessel inflammation, which is supposed to be increased in patients with type 2 diabetes mellitus (T2DM). However, whether the coronary inflammation ...

    Authors: Meng-Meng Yu, Xin Zhao, Yin-Yin Chen, Xin-Wei Tao, Jun-Bo Ge, Hang Jin and Meng-Su Zeng
    Citation: Cardiovascular Diabetology 2023 22:121
    Content type: Research Published on:

  33. Data on drug-coated balloon (DCB) treatment in the context of diabetes mellitus (DM) and multivessel coronary artery disease (CAD) are limited. We aimed to investigate the clinical impact of DCB-based revascul...

    Authors: Ae-Young Her, Eun-Seok Shin, Sunwon Kim, Bitna Kim, Tae-Hyun Kim, Chang-Bae Sohn, Byung Joo Choi, Yongwhi Park, Jung Rae Cho and Young-Hoon Jeong
    Citation: Cardiovascular Diabetology 2023 22:120
    Content type: Research Published on:

  34. We assessed the impact of 24 months of treatment with ipragliflozin, a sodium-glucose cotransporter 2 (SGLT2) inhibitor, on endothelial function in patients with type 2 diabetes as a sub-analysis of the PROTEC...

    Authors: Shinji Kishimoto, Yukihito Higashi, Takumi Imai, Kazuo Eguchi, Kazuo Fukumoto, Hirofumi Tomiyama, Koji Maemura, Atsushi Tanaka and Koichi Node
    Citation: Cardiovascular Diabetology 2023 22:119
    Content type: Research Published on:

  35. The triglyceride–glucose (TyG) index has been shown to be a new alternative measure for insulin resistance. However, no study has attempted to investigate the association of the TyG index with incident atrial ...

    Authors: Xiao Liu, Ayiguli Abudukeremu, Yuan Jiang, Zhengyu Cao, Maoxiong Wu, Jianyong Ma, Runlu Sun, Wanbing He, Zhiteng Chen, Yangxin Chen, Peng Yu, Wengen Zhu, Yuling Zhang and Jingfeng Wang
    Citation: Cardiovascular Diabetology 2023 22:118
    Content type: Research Published on:

  38. Few studies have assessed the correlation between coexisting mental disorders in participants with diabetes mellitus (DM) and the risk of heart failure (HF). Herein, we conducted a cohort study to determine th...

    Authors: Tae Kyung Yoo, Kyung-Do Han, Eun-Jung Rhee and Won-Young Lee
    Citation: Cardiovascular Diabetology 2023 22:115
    Content type: Research Published on:

  39. Metabolic abnormalities such as dyslipidemia, glucose and high blood pressure are common in diabetic patients. Visit-to-visit variabilities in these measures have been reported as potential residual cardiovasc...

    Authors: Subin Lim, Se Hwa Chung, Ju Hyeon Kim, Yong Hyun Kim, Eung Ju Kim and Hyung Joon Joo
    Citation: Cardiovascular Diabetology 2023 22:114
    Content type: Research Published on:

  40. Coronary microvascular dysfunction (CMD) is a strong determinant of prognosis in patients with chronic coronary syndrome (CCS). The triglyceride-glucose index (TyG index), an alternative method to evaluate ins...

    Authors: Wen Zhang, Lu Liu, Huiying Chen, Siqi Li, Minying Wan, Abdul-Quddus Mohammed, Bin Xu, Guoqing Yin, Xian Lv, Tingting Shi, Jassur Galip, Ayman A. Mohammed, Redhwan M. Mareai, Yawei Xu, Fuad A. Abdu and Wenliang Che
    Citation: Cardiovascular Diabetology 2023 22:113
    Content type: Research Published on:

  41. Atherosclerosis is a common co-morbidity of type 2 diabetes mellitus. Monocyte recruitment by an activated endothelium and the pro-inflammatory activity of the resulting macrophages are critical components of ...

    Authors: Heng Yu, Hunter F. Douglas, Donald Wathieu, Ryan A. Braun, Christine Edomwande, Daniel J. Lightell Jr., Thaidan Pham, Natasha C. Klingenberg, Shelia Pugh Bishop, Damir B. Khismatullin and T. Cooper Woods
    Citation: Cardiovascular Diabetology 2023 22:112
    Content type: Research Published on:

  42. The triglyceride and glucose (TyG) index has been linked to various cardiovascular diseases. However, it's still unclear whether the TyG index is associated with arterial stiffness and coronary artery calcific...

    Authors: Fuwei Liu, Qin Ling, Shaofeng Xie, Yi Xu, Menglu Liu, Qingwen Hu, Jianyong Ma, Zhiwei Yan, Yan Gao, Yujie Zhao, Wengen Zhu, Peng Yu, Jun Luo and Xiao Liu
    Citation: Cardiovascular Diabetology 2023 22:111
    Content type: Methodology Published on:

  43. This study aimed to explore the association between the triglyceride glucose index (TyG) and the risk of in-hospital and one-year mortality in patients with chronic kidney disease (CKD) and cardiovascular dise...

    Authors: Zixiang Ye, Shuoyan An, Yanxiang Gao, Enmin Xie, Xuecheng Zhao, Ziyu Guo, Yike Li, Nan Shen and Jingang Zheng
    Citation: Cardiovascular Diabetology 2023 22:110
    Content type: Research Published on:

  44. This study compared the risks of cardiovascular morbidity and mortality between patients with type 2 diabetes (T2D) with and without microvascular diseases, and between matched patients with microvascular dise...

    Authors: Fu-Shun Yen, James Cheng-Chung Wei, Ying-Hsiu Shih, Chih-Cheng Hsu and Chii-Min Hwu
    Citation: Cardiovascular Diabetology 2023 22:109
    Content type: Research Published on:

  45. The FIDELIO-DKD and FIGARO-DKD randomized clinical trials (RCTs) showed finerenone, a novel non-steroidal mineralocorticoid receptor antagonist (MRA), reduced the risk of renal and cardiovascular events in pat...

    Authors: Peter Bramlage, Stefanie Lanzinger, Steffen Mühldorfer, Karsten Milek, Anton Gillessen, Roman Veith, Tobias Ohde, Thomas Danne, Reinhard W. Holl and Jochen Seufert
    Citation: Cardiovascular Diabetology 2023 22:108
    Content type: Research Published on:

  46. Endothelial injury caused by Type 2 diabetes mellitus (T2DM) is considered as a mainstay in the pathophysiology of diabetic vascular complications (DVCs). However, the molecular mechanism of T2DM-induced endot...

    Authors: Shilong You, Jiaqi Xu, Zeyu Yin, Boquan Wu, Pengbo Wang, Mingjun Hao, Cheng Cheng, Mengke Liu, Yuanhui Zhao, Pengyu Jia, Hongkun Jiang, Da Li, Liu Cao, Xingang Zhang, Ying Zhang, Yingxian Sun…
    Citation: Cardiovascular Diabetology 2023 22:107
    Content type: Research Published on:

  47. Ischemic stroke patients with diabetes are at high risk for recurrent stroke and cardiovascular complications. Pioglitazone, a type of thiazolidinedione, has been shown to reduce cardiovascular complications i...

    Authors: Joonsang Yoo, Jimin Jeon, Minyoul Baik and Jinkwon Kim
    Citation: Cardiovascular Diabetology 2023 22:106
    Content type: Research Published on:

  48. We investigated, using population-based data, whether worse autonomic function, estimated from lower 24-hour heart rate variability (HRV), was associated with beta cell function, asse...

    Authors: Elisabetta Rinaldi, Frank CT van der Heide, Enzo Bonora, Maddalena Trombetta, Chiara Zusi, Abraham A Kroon, Miranda T Schram, Carla JH van der Kallen, Anke Wesselius, Riccardo Bonadonna, Andrea Mari, Casper G Schalkwijk, Marleen MJ van Greevenbroek and Coen DA Stehouwer
    Citation: Cardiovascular Diabetology 2023 22:105
    Content type: Research Published on:

  49. Emerging evidence supports that dihydroceramides (DhCer) and ceramides (Cer) contribute to the pathophysiology of insulin resistance and liver steatosis, and that their circulating concentrations are independe...

    Authors: Damien Denimal, Victoria Bergas, Jean-Paul Pais-de-Barros, Isabelle Simoneau, Laurent Demizieux, Patricia Passilly-Degrace, Benjamin Bouillet, Jean-Michel Petit, Alexia Rouland, Amandine Bataille, Laurence Duvillard and Bruno Vergès
    Citation: Cardiovascular Diabetology 2023 22:104
    Content type: Research Published on:

  50. Elevated serum uric acid (SUA) is regarded as a risk factor for the development of cardiovascular diseases. Triglyceride-glucose (TyG) index, a novel surrogate for insulin resistance (IR), has been proven to b...

    Authors: Zhenguo Wu, Cheng Cheng, Xiangfei Sun, Juan Wang, Dachuan Guo, Sha Chen, Yerui Zhang, Xiaoyu Liu, Li Liu, Cheng Zhang and Jianmin Yang
    Citation: Cardiovascular Diabetology 2023 22:103
    Content type: Research Published on:
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Cardiovascular Diabetology

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