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  1. Content type: Original investigation

    Hypertriglyceridemia, insulin resistance and hyperglycemia are risk factors for atherosclerosis in type 2 diabetes. Angiopoietin-like protein 8 (ANGPTL8) is a newly identified liver-derived hormone related to ...

    Authors: Tianpeng Zheng, Bo Ge, Hongbo Liu, Bo Chen, Linyuan Qin, Liuping Xiao and Jianfei Song

    Citation: Cardiovascular Diabetology 2018 17:84

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  2. Content type: Original investigation

    The relationship between long-term glycemic variability (GV) represented by visit-to-visit HbA1c variability and baroreflex sensitivity (BRS) in type 2 diabetes mellitus (T2DM) has not been clarified by previo...

    Authors: Daisuke Matsutani, Masaya Sakamoto, Soichiro Minato, Yosuke Kayama, Norihiko Takeda, Ryuzo Horiuchi and Kazunori Utsunomiya

    Citation: Cardiovascular Diabetology 2018 17:100

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  3. Content type: Review

    Diabetes mellitus currently affects over 350 million patients worldwide and is associated with many deaths from cardiovascular complications. Sodium–glucose co-transporter 2 (SGLT-2) inhibitors are a novel cla...

    Authors: Sarayut Lahnwong, Siriporn C. Chattipakorn and Nipon Chattipakorn

    Citation: Cardiovascular Diabetology 2018 17:101

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  4. Content type: Review

    Randomized controlled trials (RCTs) suggest that supplementation with omega-3 polyunsaturated fatty acids (n-3PUFAs) may favourably modify cardiometabolic biomarkers in type 2 diabetes (T2DM). Previous meta-an...

    Authors: Lauren L. O’Mahoney, Jamie Matu, Oliver J. Price, Karen M. Birch, Ramzi A. Ajjan, Diane Farrar, Robyn Tapp, Daniel J. West, Kevin Deighton and Matthew D. Campbell

    Citation: Cardiovascular Diabetology 2018 17:98

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  5. Content type: Original investigation

    Inhibiting both type 1 and 2 sodium–glucose linked cotransporter (SGLT1/2) offers the potential to not only increase glucosuria beyond that seen with selective SGLT2 inhibition alone but to reduce glucose abso...

    Authors: Kim A. Connelly, Yanling Zhang, Jean-François Desjardins, Kerri Thai and Richard E. Gilbert

    Citation: Cardiovascular Diabetology 2018 17:99

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  6. Content type: Original investigation

    The aim of the present study was to examine the association of angiopoietin-like proteins-8 (ANGPTL8) rs2278426, cholesteryl ester-transfer protein (CETP) rs708272 and endothelial nitric oxide synthase (NOS3) rs1...

    Authors: Dalia El-Lebedy

    Citation: Cardiovascular Diabetology 2018 17:97

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  7. Content type: Review

    Patients with diabetes type 2 have an increased risk for cardiovascular disease and commonly use combination therapy consisting of the anti-diabetic drug metformin and a cholesterol-lowering statin. However, b...

    Authors: Mariël F. van Stee, Albert A. de Graaf and Albert K. Groen

    Citation: Cardiovascular Diabetology 2018 17:94

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  8. Content type: Original investigation

    As body fat composition and metabolism differ between men and women, we evaluated sex-related differences in the association among epicardial adipose tissue (EAT), secretome profile, and myocardial function of...

    Authors: Dong-Hyuk Cho, Hyung Joon Joo, Mi-Na Kim, Do-Sun Lim, Wan Joo Shim and Seong-Mi Park

    Citation: Cardiovascular Diabetology 2018 17:95

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  9. Content type: Original investigation

    The prognostic impact of long-term glycemic variability on clinical outcomes in patients with heart failure (HF) and type 2 diabetes mellitus (T2DM) remains unclear. We determined and compared hemoglobin A1c (...

    Authors: Jun Gu, Jian-an Pan, Yu-qi Fan, Hui-li Zhang, Jun-feng Zhang and Chang-qian Wang

    Citation: Cardiovascular Diabetology 2018 17:96

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  10. Content type: Original investigation

    Previous studies have documented that visceral adipose tissue is positively associated with the risk of diabetes. However, the association of subcutaneous adipose tissue with diabetes risk is still in dispute....

    Authors: Peizhu Chen, Xuhong Hou, Gang Hu, Li Wei, Lei Jiao, Hongmei Wang, Siyu Chen, Jingzhu Wu, Yuqian Bao and Weiping Jia

    Citation: Cardiovascular Diabetology 2018 17:93

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  11. Content type: Original investigation

    Angiopoietin-like protein 8 (ANGPTL8), which is a novel hormone produced in liver and adipose tissue, is involved in regulating lipid metabolism. Patients with diabetes and coronary artery disease (CAD) have r...

    Authors: Xiaolu Jiao, Jiqiang He, Yunyun Yang, Song Yang, Juan Li and Yanwen Qin

    Citation: Cardiovascular Diabetology 2018 17:92

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  12. Content type: Original investigation

    Recently, two large randomized controlled trials which only included patients with underlying cardiovascular disease (CVD) or patients at high risk for CVD showed that two sodium glucose co-transporter 2 inhib...

    Authors: Young-Gun Kim, Seung Jin Han, Dae Jung Kim, Kwan-Woo Lee and Hae Jin Kim

    Citation: Cardiovascular Diabetology 2018 17:91

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  13. Content type: Original investigation

    Raised hemoglobinA1c (HbA1c) is an indicator of pre-diabetes, which is associated with increased risk of coronary artery disease. However, the detailed morphological characteristics of non-culprit plaques in a...

    Authors: Shaotao Zhang, Jiannan Dai, Haibo Jia, Sining Hu, Hongwei Du, Ning Li, Yongpeng Zou, Yanan Zou, Shenhong Jing, Yan Wang, Rong Sun and Bo Yu

    Citation: Cardiovascular Diabetology 2018 17:90

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  14. Content type: Original investigation

    Calcium/calmodulin-dependent kinase II-delta (CaMKIIδ) activity is enhanced during hyperglycemia and has been shown to alter intracellular calcium handling in cardiomyocytes, ultimately leading to reduced card...

    Authors: Lorna J. Daniels, Rachel S. Wallace, Olivia M. Nicholson, Genevieve A. Wilson, Fiona J. McDonald, Peter P. Jones, J. Chris Baldi, Regis R. Lamberts and Jeffrey R. Erickson

    Citation: Cardiovascular Diabetology 2018 17:89

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  15. Content type: Original investigation

    Chronic low-grade inflammation and associated insulin resistance and metabolic abnormalities have been proposed as ‘common soil’ for diabetes mellitus (DM) and cardiovascular disease (CVD). This paper aimed to...

    Authors: Xue Bao, Yan Borné, Linda Johnson, Iram Faqir Muhammad, Margaretha Persson, Kaijun Niu and Gunnar Engström

    Citation: Cardiovascular Diabetology 2018 17:87

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  16. Content type: Original investigation

    Local, abdominal fat depots may be related to alterations in cardiac function and morphology due to a metabolic linkage. Thus, we aimed to determine their association with subtle cardiac changes and the potent...

    Authors: Christopher L. Schlett, Roberto Lorbeer, Carolyn Arndt, Sigrid Auweter, Jürgen Machann, Holger Hetterich, Birgit Linkohr, Wolfgang Rathmann, Annette Peters and Fabian Bamberg

    Citation: Cardiovascular Diabetology 2018 17:88

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  17. Content type: Study protocol

    Recent studies reported that sodium glucose cotransporter 2 (SGLT2) inhibitors reduced the cardiovascular morbidity and mortality in patients with type 2 diabetes mellitus (T2DM) compared to placebo in contras...

    Authors: Fumika Shigiyama, Naoki Kumashiro, Ayako Fuchigami and Takahisa Hirose

    Citation: Cardiovascular Diabetology 2018 17:86

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  18. Content type: Commentary

    Recent clinical trials investigating cardiovascular (CV) safety of newer antidiabetic agents have been rapidly and largely changing the landscape of diabetes care and providing highly important clinical inform...

    Authors: Atsushi Tanaka and Koichi Node

    Citation: Cardiovascular Diabetology 2018 17:85

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  19. Content type: Original investigation

    Patients with type 2 diabetes (T2D) face a high amputation rate. We investigated the relationship between the level of amputation and the presence of micro or macro-vascular disease and related circulating bio...

    Authors: Fabrice Schneider, Pierre-Jean Saulnier, Elise Gand, Mathieu Desvergnes, Nicolas Lefort, Eric Thorin, Nathalie Thorin-Trescases, Kamel Mohammedi, Stéphanie Ragot, Jean-Baptiste Ricco and Samy Hadjadj

    Citation: Cardiovascular Diabetology 2018 17:81

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  20. Content type: Original investigation

    Advanced glycation end-products play a role in diabetic vascular complications. Their optical properties allow to estimate their accumulation in tissues by measuring the skin autofluorescence (SAF). We searche...

    Authors: C. Blanc-Bisson, F. L. Velayoudom-Cephise, A. Cougnard-Gregoire, C. Helmer, K. Rajaobelina, C. Delcourt, L. Alexandre, L. Blanco, K. Mohammedi, M. Monlun and V. Rigalleau

    Citation: Cardiovascular Diabetology 2018 17:82

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  21. Content type: Original investigation

    High-density lipoproteins (HDLs) can exert anti-atherogenic effects. On top of removing excess cholesterol through reverse cholesterol transport, HDLs play beneficial actions on endothelial function and integr...

    Authors: Daniela Lucchesi, Simona Georgiana Popa, Veronica Sancho, Laura Giusti, Monia Garofolo, Giuseppe Daniele, Laura Pucci, Roberto Miccoli, Giuseppe Penno and Stefano Del Prato

    Citation: Cardiovascular Diabetology 2018 17:78

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  22. Content type: Review

    Cardiovascular (CV) safety of one anti-diabetic medication over another remains partially delineated. We sought to assess the comparative effect on CV outcomes among novel anti-diabetic agents.

    Authors: Xiao-dong Zhuang, Xin He, Da-ya Yang, Yue Guo, Jian-gui He, Hai-peng Xiao and Xin-xue Liao

    Citation: Cardiovascular Diabetology 2018 17:79

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  23. Content type: Original investigation

    Most studies linking long-term consequences of adolescent underweight and obesity are limited to men.

    Authors: Ariel Furer, Arnon Afek, Omri Orr, Liron Gershovitz, Moran Landau Rabbi, Estela Derazne, Orit Pinhas-Hamiel, Noam Fink, Adi Leiba, Amir Tirosh, Jeremy D. Kark and Gilad Twig

    Citation: Cardiovascular Diabetology 2018 17:80

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  24. Content type: Original investigation

    Cardiovascular risk stratification is complex in type 1 diabetes. We hypothesised that traditional and diabetes-specific cardiovascular risk factors were prevalent and strongly associated with cardiovascular d...

    Authors: Anthony Pease, Arul Earnest, Sanjeeva Ranasinha, Natalie Nanayakkara, Danny Liew, Natalie Wischer, Sofianos Andrikopoulos and Sophia Zoungas

    Citation: Cardiovascular Diabetology 2018 17:77

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