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  3. A C825T polymorphism was recently identified in the gene encoding the β3 subunit of heterotrimeric G-proteins (GNB3). The T-allele is significantly associated with essential hypertension and obesity. In order to ...

    Authors: Jens Nürnberger, Sandra Dammer, Thomas Philipp, Rene R Wenzel and Rafael F Schäfers
    Citation: Cardiovascular Diabetology 2003 2:7
    Content type: Original investigation Published on:

  4. Using the streptozotocin-induced diabetic rat model, we have recently showed that the expression and function of β1-adrenoreceptor were decreased in the diabetic rat heart. However, the effect of diabetes on expr...

    Authors: U Deniz Dinçer, Şahika Güner, Aydin Tay, Ebru Arioğlu, Atilay Taşdelen, Sait Aşlamaci and Keshore R Bidasee
    Citation: Cardiovascular Diabetology 2003 2:6
    Content type: Original investigation Published on:

  5. Interleukin 8 (IL-8) is a cytokine with atherogenic properties. In vitro studies revealed that it is produced and secreted by human adipocytes. We recently reported that plasma IL-8 is increased in obese subje...

    Authors: Marek Straczkowski, Irina Kowalska, Agnieszka Nikolajuk, Stella Dzienis-Straczkowska, Malgorzata Szelachowska and Ida Kinalska
    Citation: Cardiovascular Diabetology 2003 2:5
    Content type: Original investigation Published on:

  6. The metabolic syndrome is a highly prevalent clinical entity. The recent Adult Treatment Panel (ATP III) guidelines have called specific attention to the importance of targeting the cardiovascular risk factors...

    Authors: Alexander Tenenbaum, Enrique Z Fisman and Michael Motro
    Citation: Cardiovascular Diabetology 2003 2:4
    Content type: Review Published on:

  7. Coronary plaque rupture may result from localised over expression of matrix metalloproteinases (MMPs) within the plaque by infiltrating monocyte – macrophages. As MMP expression can be promoted by the modified...

    Authors: Mark D Baugh, Jelena Gavrilovic, Isabel R Davies, David A Hughes and Mike J Sampson
    Citation: Cardiovascular Diabetology 2003 2:3
    Content type: Original investigation Published on:

  8. Cardiovascular disease accounts for at least 85 percent of deaths for those patients with type 2 diabetes mellitus (T2DM). Additionally, 75 percent of these deaths are due to ischemic heart disease.

    Authors: Melvin R Hayden and Suresh C Tyagi
    Citation: Cardiovascular Diabetology 2003 2:2
    Content type: Hypothesis Published on:

  9. Our aim is to summarize and discuss the recent literature linking diabetes mellitus with heart failure, and to address the issue of the optimal treatment for diabetic patients with heart failure.

    Authors: Christophe Bauters, Nicolas Lamblin, Eugène P Mc Fadden, Eric Van Belle, Alain Millaire and Pascal de Groote
    Citation: Cardiovascular Diabetology 2003 2:1
    Content type: Review Published on:

  10. There is little data on the relationship between novel cardiovascular risk factors and silent coronary artery disease (CAD) in diabetic patients. We investigated whether Lipoprotein(a), homocysteine and apolip...

    Authors: Carmine Gazzaruso, Adriana Garzaniti, Stefano Giordanetti, Colomba Falcone and Pietro Fratino
    Citation: Cardiovascular Diabetology 2002 1:5
    Content type: Original investigation Published on:

  11. The increase in the prevalence of insulin resistance-related metabolic syndrome, a disorder that greatly increases the risk of diabetes, heart attack and stroke, is alarming. One of the most frequent and early...

    Authors: Radka Lichnovská, Simona Gwozdziewiczová and Jirí Hrebícek
    Citation: Cardiovascular Diabetology 2002 1:4
    Content type: Original investigation Published on:

  12. Metabolic syndrome, insulin resistance, prediabetes, and overt type 2 diabetes mellitus are associated with an accelerated atherosclerosis (atheroscleropathy). This quartet is also associated with multiple met...

    Authors: Melvin R Hayden and Suresh C Tyagi
    Citation: Cardiovascular Diabetology 2002 1:3
    Content type: Review Published on:

  13. The RENAAL (Reduction of Endpoints in NIDDM with the Angiotensin II Antagonist Losartan) study is a multinational, double-blind, randomized, placebo controlled trial which was recently published. It was aimed ...

    Authors: Enrique Z Fisman, Alexander Tenenbaum and Michael Motro
    Citation: Cardiovascular Diabetology 2002 1:2
    Content type: Commentary Published on:
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ISSN: 1475-2840