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  1. Osteoprotegerin (OPG) and osteopontin (OPN) are vascular calcification inhibitors with a known role in the atherosclerotic and inflammatory process. We investigated their relationship with adverse outcomes (re...

    Authors: Nikolaos P. E. Kadoglou, Dimitrios Kapetanios, Emmanouil Korakas, Georgia Valsami, Nikolaos Tentolouris, Nikolaos Papanas, Vaia Lambadiari and Christos Karkos
    Citation: Cardiovascular Diabetology 2022 21:171
  2. Gabapentin and pregabalin are commonly prescribed medications to treat pain in patients with diabetic neuropathy. Gabapentin and pregabalin can cause fluid retention, which is hypothesized to be associated wit...

    Authors: Yiheng Pan, Pamela B. Davis, David C. Kaebler, Robert P. Blankfield and Rong Xu
    Citation: Cardiovascular Diabetology 2022 21:170
  3. The triglyceride–glucose (TyG) index, which is a reliable surrogate marker of insulin resistance (IR), has been associated with cardiovascular diseases. However, evidence of the impact of the TyG index on the ...

    Authors: Xiang Wang, Wei Xu, Qirui Song, Zinan Zhao, Xuyang Meng, Chenxi Xia, Yibo Xie, Chenguang Yang, Pengfei Jin and Fang Wang
    Citation: Cardiovascular Diabetology 2022 21:168
  4. Plasma ceramides and sphingomyelins have been independently linked to diabetes risk, glucose and insulin levels, and the risk of several cardiovascular (CVD) outcomes. However, whether individual ceramide and ...

    Authors: Paul N. Jensen, Amanda M. Fretts, Andrew N. Hoofnagle, Barbara McKnight, Barbara V. Howard, Jason G. Umans, Colleen M. Sitlani, David S. Siscovick, Irena B. King, Nona Sotoodehnia and Rozenn N. Lemaitre
    Citation: Cardiovascular Diabetology 2022 21:167
  5. Among individuals with atherosclerotic cardiovascular disease (ASCVD), type 2 diabetes mellitus (T2DM) is common and confers increased risk for morbidity and mortality. Differentiating risk is key to optimize ...

    Authors: Susanna R. Stevens, Matthew W. Segar, Ambarish Pandey, Yuliya Lokhnygina, Jennifer B. Green, Darren K. McGuire, Eberhard Standl, Eric D. Peterson and Rury R. Holman
    Citation: Cardiovascular Diabetology 2022 21:166
  6. Cardiomyocyte death contributes to cardiac pathology of diabetes. Studies have shown that the RIPK3/MLKL necroptosis signaling is activated in diabetic hearts. Deletion of RIPK3 was reported to attenuate myoca...

    Authors: Ting Cao, Rui Ni, Weimin Ding, Xiaoyun Ji, Lan Li, Guangneng Liao, Yanrong Lu, Guo-Chang Fan, Zhuxu Zhang and Tianqing Peng
    Citation: Cardiovascular Diabetology 2022 21:165
  7. Continuous glucose monitoring (CGM) shows in more detail the glycaemic pattern of diabetic subjects and provides several new parameters (“glucometrics”) to assess patients’ glycaemia and consensually guide tre...

    Authors: Carlo Di Mario, Stefano Genovese, Gaetano A. Lanza, Edoardo Mannucci, Giancarlo Marenzi, Edoardo Sciatti and Dario Pitocco
    Citation: Cardiovascular Diabetology 2022 21:164
  8. Cardiovascular (CV) outcome trials (CVOTs) of type 2 diabetes mellitus (T2DM) therapies have mostly used randomized comparison with placebo to demonstrate non-inferiority to establish that the investigational ...

    Authors: Darren K. McGuire, David D’Alessio, Stephen J. Nicholls, Steven E. Nissen, Jeffrey S. Riesmeyer, Imre Pavo, Shanthi Sethuraman, Cory R. Heilmann, John J. Kaiser and Govinda J. Weerakkody
    Citation: Cardiovascular Diabetology 2022 21:163
  9. GLP-1 receptor agonists (GLP-1 RA) and SGLT-2 inhibitors (SGLT-2i) have shown to reduce the risk of major adverse cardiovascular events (MACE), death and worsening nephropathy when added to standard of care. H...

    Authors: Marta Baviera, Andreana Foresta, Pierluca Colacioppo, Giulia Macaluso, Maria Carla Roncaglioni, Mauro Tettamanti, Ida Fortino, Stefano Genovese, Irene Caruso and Francesco Giorgino
    Citation: Cardiovascular Diabetology 2022 21:162
  10. The triglyceride-glucose (TyG) index is a reliable surrogate marker of insulin resistance and is associated with major adverse cardiovascular events (MACEs) in patients with type 2 diabetes mellitus (T2DM). Ho...

    Authors: Shi Tai, Liyao Fu, Ningjie Zhang, Rukai Yang, Yuying Zhou, Zhenhua Xing, Yongjun Wang and Shenghua Zhou
    Citation: Cardiovascular Diabetology 2022 21:161
  11. It is well known that diabetes is a prominent risk factor for cardiovascular (CV) events. The level of CV risk depends on the type and duration of diabetes, age and additional co-morbidities. Diabetes is an in...

    Authors: A. John Camm, Hani Sabbour, Oliver Schnell, Francesco Summaria and Atul Verma
    Citation: Cardiovascular Diabetology 2022 21:160
  12. Treatment algorithms define lines of glucose lowering medications (GLM) for the management of type 2 diabetes (T2D), but whether therapeutic trajectories are associated with major adverse cardiovascular events...

    Authors: Enrico Longato, Barbara Di Camillo, Giovanni Sparacino, Angelo Avogaro and Gian Paolo Fadini
    Citation: Cardiovascular Diabetology 2022 21:159
  13. The estimated glomerular filtration rate (eGFR) and the albumin-to-creatinine ratio (ACR) are risk factors for diabetes-related outcomes. A composite that captures information from both may provide a simpler w...

    Authors: Hertzel C. Gerstein, Chinthanie Ramasundarahettige, Alvero Avezum, Jan Basile, Ignacio Conget, William C. Cushman, Gilles R. Dagenais, Edward Franek, Mark Lakshmanan, Fernando Lanas, Lawrence A. Leiter, Nana Pogosova, Jeffrey Probstfield, Peter J. Raubenheimer, Matthew Riddle, Jonathan Shaw…
    Citation: Cardiovascular Diabetology 2022 21:158
  14. There is a lack of recent data reflecting the actual use of sodium-glucose cotransporter-2 (SGLT2) inhibitors for heart failure (HF) and type 2 diabetes (DM) in the superaged society. The present study investi...

    Authors: Michikazu Nakai, Yoshitaka Iwanaga, Koshiro Kanaoka, Yoko Sumita, Yuichi Nishioka, Tomoya Myojin, Shinichiro Kubo, Katsuki Okada, Tsunenari Soeda, Tatsuya Noda, Yasushi Sakata, Tomoaki Imamura, Yoshihiko Saito, Satoshi Yasuda and Yoshihiro Miyamoto
    Citation: Cardiovascular Diabetology 2022 21:157
  15. Inflammation plays a crucial role in the pathogenesis and progression of coronary artery disease (CAD). The neutrophil to lymphocyte ratio (NLR) is a novel inflammatory biomarker and its association with clini...

    Authors: Jining He, Xiaohui Bian, Chenxi Song, Rui Zhang, Sheng Yuan, Dong Yin and Kefei Dou
    Citation: Cardiovascular Diabetology 2022 21:156
  16. This study aimed to investigate the associations between the triglyceride-glucose (TyG) index in young adulthood with incident cardiovascular disease (CVD) and mortality.

    Authors: Xinghao Xu, Rihua Huang, Yifen Lin, Yue Guo, Zhenyu Xiong, Xiangbin Zhong, Xiaomin Ye, Miaohong Li, Xiaodong Zhuang and Xinxue Liao
    Citation: Cardiovascular Diabetology 2022 21:155
  17. Reduced cholesterol efflux capacity (CEC) of HDLs is likely to increase cardiovascular risk in type 1 diabetes (T1D). We aimed to assess whether improvement of glycemic control in T1D patients is associated wi...

    Authors: Damien Denimal, Serge Monier, Isabelle Simoneau, Laurence Duvillard, Bruno Vergès and Benjamin Bouillet
    Citation: Cardiovascular Diabetology 2022 21:154
  18. Prediabetes is an important risk factor of cardiovascular disease (CVD) and is associated with subclinical atherosclerosis. However, the evidence of prediabetes as a cardiovascular risk factor is mainly derive...

    Authors: Qiuyu Cao, Zhuojun Xin, Ruixin He, Tiange Wang, Min Xu, Jieli Lu, Meng Dai, Di Zhang, Yuhong Chen, Zhiyun Zhao, Shuangyuan Wang, Hong Lin, Weiqing Wang, Guang Ning, Yufang Bi, Yu Xu…
    Citation: Cardiovascular Diabetology 2022 21:153
  19. Impaired glucose tolerance (IGT) has been related to adverse cardiovascular outcomes. We investigated the added value of 1-h plasma glucose (PG) at the oral glucose tolerance test (OGTT) in predicting admissio...

    Authors: Viola Zywicki, Paola Capozza, Paolo Caravelli, Stefano Del Prato and Raffaele De Caterina
    Citation: Cardiovascular Diabetology 2022 21:152
  20. Insulin resistance and hyperinsulinemia in patients with type 2 diabetes (T2D) are adversely associated with the development and worsening of heart failure (HF). Herein, we sought to investigate the effect of ...

    Authors: Atsushi Tanaka, Takumi Imai, Michio Shimabukuro, Isao Taguchi, Akira Sezai, Shigeru Toyoda, Hirotaka Watada, Junya Ako and Koichi Node
    Citation: Cardiovascular Diabetology 2022 21:151
  21. Chronic total occlusion (CTO) of the coronary artery is a difficult problem in clinical practice. The triglycerideglucose (TyG) index is an effective risk predictor of cardiovascular risk. However, the relations...

    Authors: Yingkai Li, Songyuan He, Zheng Wu, Wenzheng Li, Wen Jian, Zichao Cheng, Cong Wang, Yuchen Shi and Jinghua Liu
    Citation: Cardiovascular Diabetology 2022 21:149
  22. Fibrin(ogen) amyloid microclots and platelet hyperactivation previously reported as a novel finding in South African patients with the coronavirus 2019 disease (COVID-19) and Long COVID/Post-Acute Sequelae of ...

    Authors: Etheresia Pretorius, Chantelle Venter, Gert Jacobus Laubscher, Maritha J Kotze, Sunday O. Oladejo, Liam R. Watson, Kanshu Rajaratnam, Bruce W. Watson and Douglas B. Kell
    Citation: Cardiovascular Diabetology 2022 21:148
  23. Sodium-glucose cotransporter 2 inhibitors (SGLT2i) improve endothelial dysfunction and reduce cardiovascular events in individuals with type 2 diabetes (T2D). Proprotein convertase subtilisin/kexin 9 (PCSK9i) ...

    Authors: Andrei C. Sposito, Ikaro Breder, Joaquim Barreto, Jessica Breder, Isabella Bonilha, Marcus Lima, Alessandra Oliveira, Vaneza Wolf, Beatriz Luchiari, Helison R. do Carmo, Daniel Munhoz, Daniela Oliveira, Otavio R. Coelho-Filho, Otavio R. Coelho, Jose Roberto Matos-Souza, Filipe A. Moura…
    Citation: Cardiovascular Diabetology 2022 21:147
  24. High glycated-hemoglobin (HbA1c) levels correlated with an elevated risk of adverse cardiovascular outcomes despite renin-angiotensin system (RAS) inhibition in type-2 diabetic (T2DM) patients with reduced eje...

    Authors: Raffaele Marfella, Nunzia D’Onofrio, Gelsomina Mansueto, Vincenzo Grimaldi, Maria Consiglia Trotta, Celestino Sardu, Ferdinando Carlo Sasso, Lucia Scisciola, Cristiano Amarelli, Salvatore Esposito, Michele D’Amico, Paolo Golino, Marisa De Feo, Giuseppe Signoriello, Pasquale Paolisso, Emanuele Gallinoro…
    Citation: Cardiovascular Diabetology 2022 21:146
  25. The Global Registry of Acute Coronary Events (GRACE) score derived from clinical parameters at the time of hospital discharge is a powerful predictor of long-term mortality and reinfarction after acute coronar...

    Authors: Shiqiang Xiong, Qiang Chen, Xu Chen, Jun Hou, Yingzhong Chen, Yu Long, Siqi Yang, Lingyao Qi, Hong Su, Wenchao Huang, Hanxiong Liu, Zhen Zhang and Lin Cai
    Citation: Cardiovascular Diabetology 2022 21:145
  26. Cardiovascular disease (CVD) is the leading cause of mortality and morbidity in patients with type 2 diabetes (T2D). Historical concerns about cardiovascular (CV) risks associated with certain glucose-lowering...

    Authors: Melanie J. Davies, Heinz Drexel, François R. Jornayvaz, Zoltan Pataky, Petar M. Seferović and Christoph Wanner
    Citation: Cardiovascular Diabetology 2022 21:144
  27. The influence of diabetes on the mortality and risk of implantable cardioverter defibrillator (ICD) therapies is still controversial, and a comprehensive assessment is lacking. We performed this systematic rev...

    Authors: Hualong Liu, Jinzhu Hu, Wen Zhuo, Rong Wan and Kui Hong
    Citation: Cardiovascular Diabetology 2022 21:143
  28. Premature coronary artery disease (PCAD) has become more common in recent years and is often associated with poor outcomes. Triglyceride-glucose (TyG) index is a simple and reliable surrogate for insulin resis...

    Authors: Zhenguo Wu, Li Liu, Weiwei Wang, Huiliang Cui, Yerui Zhang, Jiechang Xu, Wencheng Zhang, Tengfei Zheng and Jianmin Yang
    Citation: Cardiovascular Diabetology 2022 21:142
  29. It has been suggested that the baseline triglyceride-glucose (TyG) index, a simple surrogate measure for insulin resistance, is significantly associated with the occurrence of stroke. Nevertheless, the impact ...

    Authors: Zegui Huang, Xiong Ding, Qing Yue, Xianxuan Wang, Zekai Chen, Zefeng Cai, Weijian Li, Zhiwei Cai, Guanzhi Chen, Yulong Lan, Weiqiang Wu, Shouling Wu and Youren Chen
    Citation: Cardiovascular Diabetology 2022 21:141
  30. Stress induced hyperglycemia (SIH) is common among patients with ST-elevation myocardial infarction (STEMI), even in patients without diabetes mellitus. However, evidence regarding its role on the angiographic...

    Authors: Nikolaos Stalikas, Andreas S. Papazoglou, Efstratios Karagiannidis, Eleftherios Panteris, Dimitrios Moysidis, Stylianos Daios, Vasileios Anastasiou, Vasiliki Patsiou, Triantafyllia Koletsa, George Sofidis, Georgios Sianos and George Giannakoulas
    Citation: Cardiovascular Diabetology 2022 21:140
  31. Recent studies have shown that sodium-glucose cotransporter-2 inhibitors (SGLT2i) can achieve significant improvement in blood pressure in people with diabetes. Furthermore, randomized controlled trials (RCTs)...

    Authors: Min Li, Tieci Yi, Fangfang Fan, Lin Qiu, Zhi Wang, Haoyu Weng, Wei Ma, Yan Zhang and Yong Huo
    Citation: Cardiovascular Diabetology 2022 21:139
  32. Ketone monoester β-hydroxybutyrate (KEβHB) ingestion has emerged as an effective method of inducing acute ketosis. Although evidence suggests that KEβHB can offer several therapeutic benefits, whether KEβHB af...

    Authors: Yutong Liu, Sakina H. Bharmal, Wandia Kimita and Maxim S. Petrov
    Citation: Cardiovascular Diabetology 2022 21:138
  33. Several previous studies have indicated that the triglyceride-glucose index (TyG) index is associated with carotid atherosclerosis (CA); however, the evidence of the association is limited and inconsistent, wh...

    Authors: Wenzhen Li, Dajie Chen, Yueqing Tao, Zuxun Lu and Dongming Wang
    Citation: Cardiovascular Diabetology 2022 21:137
  34. The high heterogeneity in the symptoms and severity of COVID-19 makes it challenging to identify high-risk patients early in the disease. Cardiometabolic comorbidities have shown strong associations with COVID...

    Authors: Philip H. Schroeder, Laura N. Brenner, Varinderpal Kaur, Sara J. Cromer, Katrina Armstrong, Regina C. LaRocque, Edward T. Ryan, James B. Meigs, Jose C. Florez, Richelle C. Charles, Josep M. Mercader and Aaron Leong
    Citation: Cardiovascular Diabetology 2022 21:136
  35. Cardiovascular disease remains the leading cause of mortality in individuals with diabetes and improved understanding of its pathophysiology is needed. We investigated the association of a large panel of metab...

    Authors: Luis F. Ferreira-Divino, Tommi Suvitaival, Viktor Rotbain Curovic, Nete Tofte, Kajetan Trošt, Ismo M. Mattila, Simone Theilade, Signe A. Winther, Tine W. Hansen, Marie Frimodt-Møller, Cristina Legido-Quigley and Peter Rossing
    Citation: Cardiovascular Diabetology 2022 21:135
  36. We examined multi-dimensional clinical and laboratory data in participants with normoglycemia, prediabetes, and diabetes to identify characteristics of prediabetes and predictors of progression from prediabete...

    Authors: Ranee Chatterjee, Lydia Coulter Kwee, Neha Pagidipati, Lynne H. Koweek, Priyatham S. Mettu, Francois Haddad, David J. Maron, Fatima Rodriguez, Jessica L. Mega, Adrian Hernandez, Kenneth Mahaffey, Latha Palaniappan and Svati H. Shah
    Citation: Cardiovascular Diabetology 2022 21:134
  37. Evidence for the relationship between glycated hemoglobin (HbA1c) levels and risk of cardiovascular diseases (CVD) in patients with gout remained sparse and limited. This study aims to explore the associations...

    Authors: Likang Li, Gregory Y. H. Lip, Shuai Li, Jonathan D. Adachi, Lehana Thabane and Guowei Li
    Citation: Cardiovascular Diabetology 2022 21:133
  38. Prior studies of the glycemic effect of statins have been inconsistent. Also, most studies have only considered a short duration of statin use; the effect of long-term statin use on fasting glucose (FG) has no...

    Authors: Tanushree Haldar, Akinyemi Oni-Orisan, Thomas J. Hoffmann, Catherine Schaefer, Carlos Iribarren, Ronald M. Krauss, Marisa W. Medina and Neil Risch
    Citation: Cardiovascular Diabetology 2022 21:132
  39. Few studies have examined associations between genetic risk for type 2 diabetes (T2D), lifestyle, clinical risk factors, and cardiovascular disease (CVD). We aimed to investigate the association of and potenti...

    Authors: Jae-Seung Yun, Sang-Hyuk Jung, Manu Shivakumar, Brenda Xiao, Amit V. Khera, Hong-Hee Won and Dokyoon Kim
    Citation: Cardiovascular Diabetology 2022 21:131
  40. Liver pathology (LP) characteristic of non-alcoholic fatty acid disease (NAFLD)/non-alcoholic steatohepatitis (NASH) is a prevalent co-morbidity of type 2 diabetes (T2D). Accumulating evidence indicates that n...

    Authors: Brett E. Phillips, Louise Lantier, Carl Engman, Yesica Garciafigueroa, Aatur Singhi, Massimo Trucco, Christos Mantzoros, David Wasserman and Nick Giannoukakis
    Citation: Cardiovascular Diabetology 2022 21:130
  41. Mannose binding lectin (MBL) has been suggested to be associated with an impaired cardiovascular prognosis in dysglycaemic conditions, but results are still contrasting.

    Authors: Sara Meziani, Giulia Ferrannini, Mette Bjerre, Troels K. Hansen, Viveca Ritsinger, Anna Norhammar, Viveca Gyberg, Per Näsman, Lars Rydén and Linda G. Mellbin
    Citation: Cardiovascular Diabetology 2022 21:129
  42. Triglyceride-glucose (TyG) index as a reliable surrogate of insulin resistance (IR) has been shown to be related to adverse clinical outcomes in patients with acute coronary syndrome, heart failure, ischemic s...

    Authors: Ying Liao, Rongting Zhang, Shanshan Shi, Yukun Zhao, Yibo He, Lihua Liao, Xueqin Lin, Qian Guo, Yani Wang, Liling Chen, Weiguo Li, Shihai Li, Kaihong Chen and Yong Fang
    Citation: Cardiovascular Diabetology 2022 21:128
  43. Raised liver function tests (LFTs) have been correlated with multiple metabolic abnormalities and variably associated with cardiorenal outcomes. We sought to systematically test the relationship between LFT le...

    Authors: Giulia Ferrannini, Norman Rosenthal, Michael K. Hansen and Ele Ferrannini
    Citation: Cardiovascular Diabetology 2022 21:127
  44. Outcome prediction tools for patients with type 2 diabetes mellitus (T2DM) undergoing percutaneous coronary intervention (PCI) are lacking. Here, we developed a machine learning-based metabolite classifier for...

    Authors: Xue-bin Wang, Ning-hua Cui and Xia’nan Liu
    Citation: Cardiovascular Diabetology 2022 21:126
  45. Obesity is strongly associated with the development of cardiovascular disease (CVD). However, the heterogenous nature of obesity in CVD-risk is still poorly understood. We aimed to explore novel CVD biomarkers...

    Authors: Johan Korduner, Hannes Holm, Amra Jujic, Olle Melander, Manan Pareek, John Molvin, Lennart Råstam, Ulf Lindblad, Bledar Daka, Margret Leosdottir, Peter M. Nilsson, Erasmus Bachus, Michael H. Olsen and Martin Magnusson
    Citation: Cardiovascular Diabetology 2022 21:125
  46. The triglyceride-glucose (TyG) index is a new alternative measure for insulin resistance. This meta-analysis was conducted to assess the associations of the TyG index with the risks of cardiovascular diseases ...

    Authors: Xiao Liu, Ziqi Tan, Yuna Huang, Huilei Zhao, Menglu Liu, Peng Yu, Jianyong Ma, Yujie Zhao, Wengen Zhu and Jingfeng Wang
    Citation: Cardiovascular Diabetology 2022 21:124
  47. Insulin resistance (IR), endothelial dysfunction, inflammation, glucose and lipid metabolism disorders, and thrombosis are believed involved in coronary heart disease (CHD) and non-alcoholic fatty liver diseas...

    Authors: Jianqi Zhao, Hongxuan Fan, Ting Wang, Bing Yu, Shaobin Mao, Xun Wang, Wenjing Zhang, Leigang Wang, Yao Zhang, Zhaoyu Ren and Bin Liang
    Citation: Cardiovascular Diabetology 2022 21:123
  48. Diabetes is a metabolic disorder that affects millions of people worldwide. Diabetic heart disease (DHD) comprises coronary artery disease, heart failure, cardiac autonomic neuropathy, peripheral arterial dise...

    Authors: Dhananjie Chandrasekera and Rajesh Katare
    Citation: Cardiovascular Diabetology 2022 21:122
  49. Type 2 diabetes mellitus (DM) is a frequent co-morbidity among patients suffering from infective endocarditis (IE). The aim of the study was to evaluate the impact of type 2 DM on the early-, intermediate- and...

    Authors: Alexander Kogan, Anat Wieder-Finesod, Jonathan Frogel, Yael Peled-Potashnik, Eilon Ram, Ehud Raanani and Leonid Sternik
    Citation: Cardiovascular Diabetology 2022 21:120

Cardiovascular Diabetology is affiliated with Sackler Faculty of Medicine, Tel-Aviv University

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