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  1. Insulin resistance (IR) is the key feature of the metabolic syndrome (MetS); its association with peripheral arterial disease (PAD) is unclear. We hypothesized that IR is associated with both the MetS and sono...

    Authors: Alexander Vonbank, Christoph H Saely, Philipp Rein and Heinz Drexel
    Citation: Cardiovascular Diabetology 2013 12:106
  2. Adipokines, including adipocyte fatty acid-binding protein (A-FABP), have been demonstrated to be involved in the pathogenesis of atherosclerosis. In the present study, we investigated the association of circu...

    Authors: Chi-Lun Huang, Yen-Wen Wu, Chih-Cheng Wu, Lin Lin, Yu-Chin Wu, Pei-Ying Hsu, Yuh-Shiun Jong and Wei-Shiung Yang
    Citation: Cardiovascular Diabetology 2013 12:105
  3. Dyslipidemia is a common complication in patients with diabetes and is involved in being prone to cardiovascular disease. The risk of coronary artery disease is known to be lower in light-to-moderate drinkers ...

    Authors: Tomoko Shimomura and Ichiro Wakabayashi
    Citation: Cardiovascular Diabetology 2013 12:104
  4. Genetic variants of the FTO gene rs9939609 A/T and the MC4R gene rs17782313 C/T have been associated with obesity. Individuals with mutations in MC4R gene have lower blood pressure (BP), independently of obesity....

    Authors: Aline Marcadenti, Flavio D Fuchs, Ursula Matte, Fernanda Sperb, Leila B Moreira and Sandra C Fuchs
    Citation: Cardiovascular Diabetology 2013 12:103
  5. Patients with type 2 diabetes are at increased risk for both, left ventricular (LV)-dilatation and myocardial infarction (MI) following the rupture of a vulnerable plaque. This study investigated the to date i...

    Authors: Mathias Burgmaier, Michael Frick, Ana Liberman, Simone Battermann, Martin Hellmich, Walter Lehmacher, Agnes Jaskolka, Nikolaus Marx and Sebastian Reith
    Citation: Cardiovascular Diabetology 2013 12:102
  6. Exercise causes physiological cardiac hypertrophy and benefits the diabetic heart. Mammalian switch-independent 3A (mSin3A) and histone deacetylases (HDACs) 1 and 2 regulate hypertrophic genes through associat...

    Authors: Emily J Cox and Susan A Marsh
    Citation: Cardiovascular Diabetology 2013 12:101
  7. Icosapent ethyl (IPE) is a high-purity prescription form of eicosapentaenoic acid (EPA) ethyl ester indicated as an adjunct to diet to reduce triglyceride (TG) levels in adult patients with severe (≥500 mg/dL)...

    Authors: Eliot A Brinton, Christie M Ballantyne, Harold E Bays, John J Kastelein, Rene A Braeckman and Paresh N Soni
    Citation: Cardiovascular Diabetology 2013 12:100
  8. Glucose intolerance and cardiovascular complications are major symptoms in patients with diabetes. Many therapies have proven beneficial in treating diabetes in animals by protecting the cardiovascular system ...

    Authors: Yi-Jin Ho, Wen-Pin Chen, Tzong-Cherng Chi, Ching-Chia Chang Chien, An-Sheng Lee, Hsi-Lin Chiu, Yueh-Hsiung Kuo and Ming-Jai Su
    Citation: Cardiovascular Diabetology 2013 12:99
  9. Previous reports have clearly indicated a significant relationship between hemoglobin (Hb) A1c change from one visit to the next and microvascular complications, especially nephropathy (albuminuria and albuminuri...

    Authors: Giuseppe Penno, Anna Solini, Giacomo Zoppini, Emanuela Orsi, Cecilia Fondelli, Gianpaolo Zerbini, Susanna Morano, Franco Cavalot, Olga Lamacchia, Roberto Trevisan, Monica Vedovato and Giuseppe Pugliese
    Citation: Cardiovascular Diabetology 2013 12:98
  10. It has been reported that hyperglycemia following hypoglycemia produces an ischemia-reperfusion-like effect in type 1 diabetes. In this study the possibility that GLP-1 has a protective effect on this phenomen...

    Authors: Antonio Ceriello, Anna Novials, Emilio Ortega, Silvia Canivell, Gemma Pujadas, Lucia La Sala, Loredana Bucciarelli, Maurizio Rondinelli and Stefano Genovese
    Citation: Cardiovascular Diabetology 2013 12:97
  11. Glycemic memory of endothelial cells is an effect of long-lasting hyperglycemia and is a cause of various diabetics complications, that arises despite of the treatment targeted towards returning low glucose le...

    Authors: Marta Targosz-Korecka, Grzegorz D Brzezinka, Katarzyna E Malek, Ewa Stȩpień and Marek Szymonski
    Citation: Cardiovascular Diabetology 2013 12:96
  12. Patients with type 2 diabetes (T2D) are at elevated risk for cardiovascular disease (CVD) events and mortality. Recent studies have assessed the impact of genetic variants affecting high-density lipoprotein ch...

    Authors: Laura M Raffield, Amanda J Cox, Fang-Chi Hsu, Maggie C-Y Ng, Carl D Langefeld, J Jeffrey Carr, Barry I Freedman and Donald W Bowden
    Citation: Cardiovascular Diabetology 2013 12:95
  13. Type 2 diabetes mellitus (T2DM) is associated with subclinical myocardial injury although the underlying mechanism is uncertain. We postulated that arterial stiffness, endothelial dysfunction and subclinical a...

    Authors: Kai-Hang Yiu, Chun-Ting Zhao, Yan Chen, Chung-Wah Siu, Yap-Hang Chan, Kui-Kai Lau, Shasha Liu, Chu-Pak Lau and Hung-Fat Tse
    Citation: Cardiovascular Diabetology 2013 12:94
  14. Increased arterial stiffness is a cardiovascular outcome of metabolic syndrome (MetS). The chromosome 9p21 locus has been identified as a major locus for risk of coronary artery disease (CAD). The single nucle...

    Authors: Suphawadee Phababpha, Upa Kukongviriyapan, Poungrat Pakdeechote, Laddawan Senggunprai, Veerapol Kukongviriyapan, Chatri Settasatian, Pyatat Tatsanavivat, Phongsak Intharaphet, Vichai Senthong, Nantarat Komanasin, Nongnuch Settasatian and Stephen E Greenwald
    Citation: Cardiovascular Diabetology 2013 12:93
  15. Hyperglycemia, a risk factor for development of cardiovascular disease, causes endothelial dysfunction. Alpha-glucosidase inhibitors (α-GIs) improve postprandial hyperglycemia (PPHG) and may have favorable eff...

    Authors: Daisuke Kitano, Masaaki Chiku, Yuxin Li, Yasuo Okumura, Daisuke Fukamachi, Tadateru Takayama, Takafumi Hiro, Satoshi Saito and Atsushi Hirayama
    Citation: Cardiovascular Diabetology 2013 12:92
  16. Diabetic patients, through incompletely understood mechanisms, endure exacerbated ischemic heart injury compared to non-diabetic patients. Intermedin (IMD) is a novel calcitonin gene-related peptide (CGRP) sup...

    Authors: Hong Li, Yunfei Bian, Nana Zhang, Jia Guo, Cheng Wang, Wayne Bond Lau and Chuanshi Xiao
    Citation: Cardiovascular Diabetology 2013 12:91
  17. The increase in fructose consumption is paralleled by a higher incidence of metabolic syndrome, and consequently, cardiovascular disease mortality. We examined the effects of 8 weeks of low intensity exercise ...

    Authors: Eduardo Morvan, Nathalia Edviges Alves Lima, Jacqueline Freire Machi, Cristiano Mostarda, Kátia De Angelis, Maria Cláudia Irigoyen, Rogério Brandão Wichi, Bruno Rodrigues and Laura Beatriz Mesiano Maifrino
    Citation: Cardiovascular Diabetology 2013 12:89
  18. Although many Asian type 2 diabetic patients have been considered to be not obese and have low capacity of insulin secretion, the proportion of obese patients with visceral fat accumulation has increased in re...

    Authors: Hirofumi Nagao, Susumu Kashine, Hitoshi Nishizawa, Takuya Okada, Takekazu Kimura, Ayumu Hirata, Shiro Fukuda, Junji Kozawa, Norikazu Maeda, Tetsuhiro Kitamura, Tetsuyuki Yasuda, Kohei Okita, Toshiyuki Hibuse, Mamiko Tsugawa, Akihisa Imagawa, Tohru Funahashi…
    Citation: Cardiovascular Diabetology 2013 12:88
  19. Clopidogrel and aspirin are antiplatelet agents that are recommended to reduce the risk of recurrent stroke and other cardiovascular events. Combination therapy of clopidogrel and aspirin has been shown to inc...

    Authors: Yasuo Takahashi, Yayoi Nishida, Tomohiro Nakayama and Satoshi Asai
    Citation: Cardiovascular Diabetology 2013 12:87
  20. In the general population, metabolic syndrome (MetS) is correlated with visceral fat and a risk factor for cardiovascular disease (CVD); however, little is known about the significance of abdominal fat and its...

    Authors: Jenq-Wen Huang, Chung-Yi Yang, Hon-Yen Wu, Kao-Lang Liu, Chi-Ting Su, Cho-Kai Wu, Jen-Kuang Lee, Chih-Kang Chiang, Hui-Teng Cheng, Yu-Chung Lien and Kuan-Yu Hung
    Citation: Cardiovascular Diabetology 2013 12:86
  21. Although cardiac autonomic neuropathy is one of major complications of diabetes mellitus (DM), anatomical data on cardiac innervation of diabetic animal models is scant and controversial. We performed this stu...

    Authors: Darius Batulevicius, Thomas Frese, Elmar Peschke, Dainius H Pauza and Vaida Batuleviciene
    Citation: Cardiovascular Diabetology 2013 12:85
  22. Although dipyridamole is a widely used pharmacological stress agent, the direct effects on myocardium are not entirely known. Diabetic cardiomyopathy can be investigated by 2D-strain echocardiography. The aim ...

    Authors: Thomas Cognet, Paul-Louis Vervueren, Laurent Dercle, Delphine Bastié, Rainui Richaud, Matthieu Berry, Pauline Marchal, Matthieu Gautier, Audrey Fouilloux, Michel Galinier, Didier Carrié, Pierre Massabuau, Isabelle Berry and Olivier Lairez
    Citation: Cardiovascular Diabetology 2013 12:84
  23. Physical activity has been associated with lower cardiovascular mortality in people with diabetes, but how diabetes severity influence this association has not been extensively studied.

    Authors: Børge Moe, Liv Berit Augestad and Tom IL Nilsen
    Citation: Cardiovascular Diabetology 2013 12:83
  24. Dyslipidemia is a major risk factor for cardiovascular (CV) disease – the primary cause of death, worldwide. Although reducing levels of low-density lipoprotein-cholesterol can significantly reduce CV risk, a ...

    Authors: Jean-Charles Fruchart
    Citation: Cardiovascular Diabetology 2013 12:82
  25. The panoply of treatment algorithms, periodically released to improve guidance, is one mean to face therapeutic uncertainty in pharmacological management of hyperglycemia in type 2 diabetes, especially after m...

    Authors: Katherine Esposito, Sandro Gentile, Riccardo Candido, Alberto De Micheli, Marco Gallo, Gerardo Medea and Antonio Ceriello
    Citation: Cardiovascular Diabetology 2013 12:81
  26. The term cardiometabolic disease encompasses a range of lifestyle-related conditions, including Metabolic syndrome (MetS) and type 2 diabetes (T2D), that are characterized by different combinations of cardiova...

    Authors: Henry Ginsberg
    Citation: Cardiovascular Diabetology 2013 12(Suppl 1):S1

    This article is part of a Supplement: Volume 12 Supplement 1

  27. Both hyperglycaemia and dendritic cells (DCs) play causative roles in atherosclerosis. However, whether they interact in atherosclerosis remains uncertain. Therefore, we examined whether high glucose could reg...

    Authors: Hao Lu, Kang Yao, Dong Huang, Aijun Sun, Yunzeng Zou, Juying Qian and Junbo Ge
    Citation: Cardiovascular Diabetology 2013 12:80
  28. The diagnosis of diabetes mellitus (DM) is based on either fasting plasma glucose levels or an oral glucose tolerance test (OGTT). Recently, an HbA1c value of ≥ 48 mmol/mol (6.5%) has been included as an addition...

    Authors: Iren D Hjellestad, Marianne C Astor, Roy M Nilsen, Eirik Søfteland and Torbjørn Jonung
    Citation: Cardiovascular Diabetology 2013 12:79
  29. Little is known about the impact of sex-specific differences in the management of type 1 diabetes (T1DM).

    Authors: Alexandra Kautzky-Willer, Kathrin Stich, Juliane Hintersteiner, Alexander Kautzky, Majid Reza Kamyar, Johannes Saukel, Julienne Johnson and Rosa Lemmens-Gruber
    Citation: Cardiovascular Diabetology 2013 12:78
  30. Fatty liver is associated with insulin resistance, dyslipidemia, and obesity and is therefore considered a phenotype of metabolic syndrome. However, less is known regarding the metabolic abnormalities associat...

    Authors: Wan-Chen Wu and Chih-Yuan Wang
    Citation: Cardiovascular Diabetology 2013 12:77
  31. The predictive potentials of neck circumference (NC) for cardio-metabolic risks remain uncertain. The aim of this study was to investigate whether NC independently contributes to the prediction of cardio-metab...

    Authors: Jing-ya Zhou, Hui Ge, Ming-fan Zhu, Li-jun Wang, Li Chen, Yao-zong Tan, Yu-ming Chen and Hui-lian Zhu
    Citation: Cardiovascular Diabetology 2013 12:76
  32. Cardiac dysfunction is well-described in endotoxemia and diagnosed in up to 60% of patients with endotoxic shock. ATP-sensitive potassium (KATP) channels are critical to cardiac function. This study investigates ...

    Authors: Zhong-Wei Yang, Ji-Kuai Chen, Min Ni, Ting Zhao, Ya-Ping Deng, Xia Tao, Guo-Jun Jiang and Fu-Ming Shen
    Citation: Cardiovascular Diabetology 2013 12:75
  33. Post-challenge hyperglycemia (PH) is well-established as one of risk factors for coronary artery disease. However, it remains unclear whether PH affects clinical outcomes in patients with stable angina undergo...

    Authors: Shoichi Kuramitsu, Hiroyoshi Yokoi, Takenori Domei, Akihiro Nomura, Hirotoshi Watanabe, Kyohei Yamaji, Yoshimitsu Soga, Takeshi Arita, Katsuhiro Kondo, Shinichi Shirai, Kenji Ando, Koyu Sakai, Masashi Iwabuchi, Hedeyuki Nosaka and Masakiyo Nobuyoshi
    Citation: Cardiovascular Diabetology 2013 12:74
  34. Treatment with the alpha-glucosidase inhibitor (AGI) acarbose is associated with a significant reduction the risk of cardiovascular events. However, the underlying mechanisms of this effect are unclear. AGIs w...

    Authors: Miao-yan Zheng, Ju-hong Yang, Chun-yan Shan, Hong-tao Zhou, Yan-guang Xu, Ying Wang, Hui-zhu Ren, Bao-cheng Chang and Li-ming Chen
    Citation: Cardiovascular Diabetology 2013 12:73
  35. Circulating adipocyte fatty acid-binding protein (FABP4) levels are considered to be a link between obesity, insulin resistance, diabetes, and cardiovascular (CV) diseases. In vitro, FABP4 has exhibited cardiodep...

    Authors: Anna Cabré, Pilar Valdovinos, Iolanda Lázaro, Gil Bonet, Alfredo Bardají and Lluís Masana
    Citation: Cardiovascular Diabetology 2013 12:72
  36. Angiotensin receptor blockers (ARBs) are reported to provide direct protection to many organs by controlling inflammation and decreasing oxidant stress. Pioglitazone, an anti-diabetic agent that improves insul...

    Authors: Hirofumi Suzuki, Masaya Sakamoto, Takeshi Hayashi, Hiroyuki Iuchi, Kennosuke Ohashi, Tsuyoshi Isaka, Noriko Sakamoto, Yosuke Kayama, Katsuyoshi Tojo, Michihiro Yoshimura and Kazunori Utsunomiya
    Citation: Cardiovascular Diabetology 2013 12:71
  37. Empagliflozin is a potent, selective sodium glucose cotransporter 2 (SGLT2) inhibitor in development as an oral antidiabetic treatment. This QT interval study assessed potential effects of empagliflozin on ven...

    Authors: Arne Ring, Tobias Brand, Sreeraj Macha, Kerstin Breithaupt-Groegler, Gudrun Simons, Beate Walter, Hans J Woerle and Uli C Broedl
    Citation: Cardiovascular Diabetology 2013 12:70
  38. Diabetic cardiovascular complications are characterised by oxidative stress-induced endothelial dysfunction. Uncoupling protein 2 (UCP2) is a regulator of mitochondrial reactive oxygen species (ROS) generation...

    Authors: Jing Sun, Yunfei Pu, Peijian Wang, Sijiao Chen, Yu Zhao, Chan Liu, Qianhui Shang, Zhiming Zhu and Daoyan Liu
    Citation: Cardiovascular Diabetology 2013 12:69
  39. Risk stratification in individuals with type 2 diabetes (T2D) remains an important priority in the management of associated morbidity and mortality, including from cardiovascular disease (CVD). The current inv...

    Authors: Amanda J Cox, Fang-Chi Hsu, J Jeffrey Carr, Barry I Freedman and Donald W Bowden
    Citation: Cardiovascular Diabetology 2013 12:68
  40. Adiponectin, an adipokine facilitating insulin action, has antiatherogenic effects. This study investigated whether common single nucleotide polymorphisms (SNPs) in the adiponectin gene influenced plasma adipo...

    Authors: Guoxin Tong, Ningfu Wang, Jianhang Leng, Xiaoshan Tong, Yun Shen, Jianmin Yang, Xianhua Ye, Liang Zhou and Yujie Zhou
    Citation: Cardiovascular Diabetology 2013 12:67
  41. Insulin resistance (IR) is currently considered a crucial cardiovascular (CV) risk factor, which seems to play a dominant role in the evolution toward cardiac and vascular impairment. Early IR-induced cardiac ...

    Authors: Christian Cadeddu, Silvio Nocco, Davide Piano, Martino Deidda, Efisio Cossu, Marco Giorgio Baroni and Giuseppe Mercuro
    Citation: Cardiovascular Diabetology 2013 12:66
  42. Although hypercaloric interventions are associated with nutritional, endocrine, metabolic, and cardiovascular disorders in obesity experiments, a rational distinction between the effects of excess adiposity an...

    Authors: Silvio A Oliveira Junior, Carlos R Padovani, Sergio A Rodrigues, Nilza R Silva, Paula F Martinez, Dijon HS Campos, Marina P Okoshi, Katashi Okoshi, Maeli Dal-Pai and Antonio C Cicogna
    Citation: Cardiovascular Diabetology 2013 12:65
  43. Endothelial dysfunction, largely dependent on impaired nitric oxide bioavailability, has been reportedly associated with incident type 2 diabetes. Our aim was to test the hypothesis that asymmetric dimethylarg...

    Authors: Andrzej Surdacki, Olga Kruszelnicka, Tomasz Rakowski, Aleksandra Jaźwińska-Kozuba and Jacek S Dubiel
    Citation: Cardiovascular Diabetology 2013 12:64
  44. The most important function of red blood cells (RBCs) is the carrying of oxygen, but they are also involved in inflammatory processes and during coagulation. RBCs are extremely deformable and elastic, as they ...

    Authors: Etheresia Pretorius
    Citation: Cardiovascular Diabetology 2013 12:63
  45. Metformin is, if not contraindicated and if tolerated, usually preferred over other antidiabetic drugs for the first line treatment of type-2 diabetes. The particular decision on which antidiabetic agent to us...

    Authors: Diethelm Tschöpe, Markolf Hanefeld, Juris J Meier, Anselm K Gitt, Martin Halle, Peter Bramlage and Petra-Maria Schumm-Draeger
    Citation: Cardiovascular Diabetology 2013 12:62
  46. The aim of this study is to evaluate the effect of gender and menopause in cardiometabolic risk in a type 2 diabetes mellitus (T2DM) population, based on classical and non-traditional markers.

    Authors: Filipa Mascarenhas-Melo, Daniela Marado, Filipe Palavra, José Sereno, Álvaro Coelho, Rui Pinto, Edite Teixeira-Lemos, Frederico Teixeira and Flávio Reis
    Citation: Cardiovascular Diabetology 2013 12:61
  47. In patients with type 2 diabetes mellitus (T2DM), hypertension and microalbuminuria are predictive markers for increased renal and cardiovascular risk. This post hoc analysis of data from a global development pro...

    Authors: Maximilian von Eynatten, Yan Gong, Angela Emser and Hans-Juergen Woerle
    Citation: Cardiovascular Diabetology 2013 12:60

Cardiovascular Diabetology is affiliated with Sackler Faculty of Medicine, Tel-Aviv University

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