Table 3 Baseline-adjusted vascular outcomes after intervention and after 3-month washout

Vascular outcomes after 8-week intervention

 Baseline-adjusted systolic BP at 8-weeks (mmHg)

130 (2.7)

133 (2.7)

128 (2.6)

0.38

 Baseline-adjusted diastolic BP at 8-weeks (mmHg)

79 (1.7)

81 (1.7)

78 (1.7)

0.34

 Baseline-adjusted heart rate at 8-weeks (bpm)

71 (1.6)

72 (1.7)

71 (1.6)

0.91

 Baseline-adjusted RHI at 8-weeks

2.07 (0.10)

2.00 (0.10)

1.81 (0.10)

0.19

Vascular outcomes after 3-month washout

 Baseline-adjusted systolic BP at 20-weeks (mmHg)

133 (2.1)

132 (2.0)

128 (1.9)

0.25

 Baseline-adjusted diastolic BP at 20-weeks (mmHg)

83 (1.6)

81 (1.5)

79 (1.5)

0.28

 Baseline-adjusted heart rate at 20-weeks (bpm)

70 (1.6)

72 (1.6)

69 (1.5)

0.53

 Baseline-adjusted RHI at 20-weeks

1.74 (0.10)

1.87 (0.09)

1.96 (0.09)

0.25