Fig. 1

Interaction of sex and selenium with signs of the metabolic syndrome. Sex and selenium levels were found to have significant interaction with BMI and proportion of diabetes mellitus in both PREVEND (1A: pinteraction < 0.001; 1B: pinteraction = 0.040, resp.) and BIOSTAT-CHF (1C: pinteraction = 0.021; 1D: pinteraction = 0.024, resp.). Females with lower selenium levels had a higher BMI and higher prevalence of diabetes, whereas in males, higher selenium associated to an increased BMI and prevalence of diabetes