Alfieri O, Bongani M, Mayosi SJP, Sarrafzadegan N, Virmani R. Exploring unknowns in cardiology. Nat Rev Cardiol. 2014;11:664–70.
Article
Google Scholar
Stary HC, Chandler AB, Glagov S, Guyton JR, Insull W Jr, Rosenfeld ME, et al. A definition of initial, fatty streak, and intermediate lesions of atherosclerosis A report from the Committee on Vascular Lesions of the Council on Arteriosclerosis American Heart Association. Circulation. 1994;89:2462–78.
Article
CAS
Google Scholar
Libby P, Folco EJ, Esper RJ. Inmunidad, inflamación y ateroesclerosis. In: Esper RJ, Vilariño JO (Eds): Progresos en Ateroesclerosis, Buenos Aires, Ediciones Médicas del Sur, 2011, p. 23–47.
Viles-Gonzalez JF, Fuster V, Esper RJ, Vilariño JO, Badimon JJ: Enfermedad Aterotrombótica. In: Esper RJ (Ed): Aterotrombosis en el tercer milenio. Barcelona, Prous Sciences, 2004, p. 1–22.
Esper RJ. Ateroesclerosis, una enfermedad inmuno-inflamatoria. Prensa Med Argent. 2009;96:552–70.
Google Scholar
Esper RJ, Nordaby RA, Vilariño JO, Paragano A, Cacharrón JL, Machado RA. Endothelial dysfunction: a comprehensive appraisal. Cardiovasc Diabetol. 2006; 5: 4. https://doi.org/10.1186/1475-2843-5-4. http://www.cardiab.com/content/5/1/4.
Ridker PM, Lüscher TF. Anti-inflammatory therapies for cardiovascular diseases. Eur Heart J. 2014;35:1782–91.
Article
CAS
Google Scholar
Crea F, Liuzzo G. Anti-inflammatory treatment of acute coronary syndromes: the need for precision medicine. Eur Heart J. 2016;37:2414–6.
Article
Google Scholar
Choy EH, Kavanaugh AF, Jones SA. The problem of choise current biologic agents and future prospects in RA. Nat Rheumatol. 2013;9:154–63.
Article
CAS
Google Scholar
Liuzzo G, Trotta F, Pedicino D. Interleukin-17 in atherosclerosis and cardiovascular disease: the good, the bad and the unknow. Eur Heart J. 2013;34:556–9.
Article
Google Scholar
Feinberg MW. No small task: therapeutic targeting of Lp(a) for cardiovascular disease. Lancet. 2016;388:2211–2.
Article
Google Scholar
Lüscher TF. Frontiers in precision medicine: genes and their modulation by miRNAs. Eur Heart J. 2016;37:3247–50.
Article
Google Scholar
El-Mowafy AM. Advances in averting cardiovascular anomalies to diabetes. J Cardiovasc Med. 2009;1:18–20. https://doi.org/10.5083/ejcm.20424884.05.
Article
Google Scholar
Fernández-Gimenez R, Al-Kazar M, Jaslow R, Carvajal I, Fuster V. Children present a window of opportunity for promoting health. J Am Col Cardiol. 2018;72:3310–9.
Article
Google Scholar
El-Lebedy D. Interaction between endothelial nitric oxide synthase rs1799983, cholesteryl ester-transfer protein rs708272 and angiopoietin-like protein 8 rs2278426 gene variants highly elevates the risk of type 2 diabetes mellitus and cardiovascular disease. Cardiovasc Diabetol. 2018;17:97. https://doi.org/10.1186/s12933-018-0742-8.
Article
PubMed
PubMed Central
Google Scholar
Fandini GP, Avogaro A. How to interpret the role of SDF-1α on diabetic complications during therapy with DPP-4 inhibitors. Cardiovasc Diabetol. 2018;17:22. https://doi.org/10.1186/s12933-018-0668-1.
Article
Google Scholar
Bogari NM, Aljohani A, Amin AA, Al-Allaf FA, Dannoun A, Taher MM, et al. A genetic variant c.553G > T (rs2075291) in the apolipoprotein A5 gene is associated with altered triglycerides levels in coronary artery disease (CAD) patients with lipid lowering drug. BMC Cardiovasc Disorders. 2019;19:2. https://doi.org/10.1186/s12872-018-0965-3.
Article
Google Scholar
Esper RJ, Antivero Esper P. Depresión, ataques de pánico, estados de ánimo y eventos cardiovasculares. In: Esper RJ, Vilariño JO (Eds): Prevención Cardiovascular, Desafíos y Oportunidades. Buenos Aires, Intermedica, 2014, p: 205-218.
Sipido KR, Tedgui A, Kristensen SD, Pasterkamp G, Schunkert H. Identifying needs and opportunities for advancing translational research in cardiovascular disease. Cardiovasc Res. 2009;83:425–35.
Article
CAS
Google Scholar
Indice de Mortalidad por Accidentes. Cumbre Anual del International Transport Forum (ITF) y Organización para la Cooperación y el Desarrollo Económicos (OCDE). Buenos Aires, La Nación, Argentina, 29 de mayo de 2015.
Fleitas Ortiz de Rosas, D. Homicidios años 2002-2012. Asociación para políticas públicas. Buenos Aires, La Nación, Argentina, 15 de octubre 2014.
Lüscher TF. Takotsubo. A japanese contribution to cardiology. Eur Heart J. 2016;37:2803–5.
Article
Google Scholar
Aukrust P, Halvorsen B, Yndestad A, Ueland T, Øie E, Otterdal K, et al. Chemokines and cardiovascular risk. Arterioscler Thromb Vasc Biol. 2008;28:1900–19.
Article
Google Scholar
Wang TJ, Gona P, Larson MG, Tofler GH, Levy D, Newton-Cheh C, Jacques PF, et al. Multiple biomarkers for the prediction of first major cardiovascular events and death. N Engl J Med. 2006;355:2631–9.
Article
CAS
Google Scholar
Ware JH. The limitations of risk factors as prognostic tools. N Engl J Med. 2006;355:2615–7.
Article
CAS
Google Scholar
Badimon JJ, García MJ. Diagnóstico de la aterosclerosis por imágenes. In: Esper RJ, Vilariño JO (Eds): Progresos en Aterotrombosis. Buenos Aires, Ediciones Médicas del Sur, 2011; p. 283–98.
Kopp AF, Ohnesorge B, Becker C, Schröder S, Heuschmid M, Küttner A, et al. Reproducibility and accuracy of coronary calcium measurements with multidetector row versus electron-beam CT. Radiology. 2002;225:113–9.
Article
CAS
Google Scholar
Arbab-Zadeh A, Fuster V. The risk continuum of atherosclerosis and its implications for defining chd by coronary angiography. J Am Coll Cardiol. 2016;68:2467–78.
Article
Google Scholar
Lichtman KH, Froelicher ES, Blumenthal JA, Carney RM, Dering LV, Frasure-Smith N, et al. Depression as a risk factor for poor prognosis among patients with acute coronary syndrome: systematic review and recommendations. A scientific statement from the American Heart Association. Circulation. 2014;129:1350–69.
Article
Google Scholar
Kubzansky LD, Sparrow LD, Vokonas P. Veterans affairs normative aging study minnesota multiphasic personality inventory bipolar revised optimism-pessimism scale. Psychosom Med. 2001;63:910–6.
Article
CAS
Google Scholar
Cediel G, Rueda F, Oxvig C, Oliveras T, Labata C, de Diego O, et al. Prognostic value of the Stanniocalcin-2/PAPP-A/IGFBP-4 axis in ST-segment elevation myocardial infarction. Cardiovasc Diabetol. 2018;17:63. https://doi.org/10.1186/s12933-018-0710-3.
Article
PubMed
PubMed Central
Google Scholar
Zhang S, Dai J, Jia H, Hu S, Du H, Li N, et al. Non-culprit plaque characteristics in acute coronary syndrome patients with raised hemoglobinA1c: an intravascular optical coherence tomography study. Cardiovasc Diabetol. 2018;17:90. https://doi.org/10.1186/s12933-018-0729-5.
Article
PubMed
PubMed Central
Google Scholar
Kobayashi N, Hata N, Tsaurumi M, Shibata Y, Okazaki H, Shirakabe A, Takano M, Seino Y, Shimizu W. Relation of coronary culprit morphology determined by optical coherence tomography and cardiac outcomes to preinfarction angina in patients with acute myocardial infarction. Int J Cardiol. 2018;269:365.
Article
Google Scholar
Fuster V. Conferencia Inaugural 40 Congreso Argentino de Cardiología. Buenos Aires, 2014; Octubre 16.
Esper RJ., Vilariño JO. Riesgo Residual, Endotelio, Genética y Tratamiento Personalizado. In: Esper RJ, Vilariño JO (Eds): Progresos en Aterotrombosis. Buenos Aires, Ediciones Médicas del Sur, 2011, p. 109–126.
Sachdeva A, Cannon CP, Deedwania PC, LaBresh KA, Smith SC Jr, Dai D, et al. Lipid Levels in patients hospitalized with coronary artery disease: an analysis of 136.905 hospitalizations in Get with the Guidelines. Am Heart J. 2009;157:111–7.
Article
CAS
Google Scholar
Khot UN, Khot MB, Bajzer CT, Sapp SK, Magnus Ohman E, Brener SJ, et al. Prevalence of conventional risk factors in patients with coronary heart disease. JAMA. 2003;290:898–904.
Article
Google Scholar
Gotto AM, Moon J. Dislipidemias. In: Esper RJ, Vilariño JO (Eds): Progresos en aterotrombosis. Buenos Aires, Ediciones Médicas del Sur 2011, p. 79–96.
Lüscher TF. Manejo actual de los desórdenes lipídicos. Enfoques entre las Guías Europeas (ESC/EAS) y americanas (ACC/AHA). In: Esper RJ, Vilariño JO (Eds): Prevención Cardiovascular. Desafíos y Oportunidades. Buenos Aires, Intermedica, 2015, p. 53–62.
Ference BA, Robinson JG, Brook RD, Catapano AL, Chapman J, Neff DR, et al. Variation in PCSK9 and HMGCR and risk of cardiovascular disease and diabetes. N Engl J Med. 2016;375:2144–53.
Article
CAS
Google Scholar
Stroes ES, Thompson PD, Corsini A, Vladutiu GD, Raal FJ, Ray KK, et al. Statin-associated muscle symptoms: impact on statin therapy-European Atherosclerosis Society Consensus Panel statement on assessment, aetiology, and management. Eur Heart J. 2015;36:1015–22.
Article
Google Scholar
Kim K, Lee SH, Lee KY. Efect of statins on fasting glucose in non-diabetic individuals: nationwide population-based health examination in Korea. Cardiovasc Diabetol. 2018;17:155. https://doi.org/10.1186/s12933-018-0799-4.
Article
PubMed
PubMed Central
Google Scholar
Yang SH, Xia R, Cui CJ, Wang Y, Du Y, Chen ZG, et al. Liraglutide downregulates hepatic LDL receptor and PCSK9 expression in HepG2 cells and db/db mice through a HNF-1a dependent mechanism. Cardiovasc Diabetol. 2018;17:48. https://doi.org/10.1186/s12933-018-0689-9.
Article
CAS
PubMed
PubMed Central
Google Scholar
Kaufman TM, Warden BA, Minnier J, Miles JR, Barton Duell P, Purnell JQ, et al. Application of PCSK9 inhibitors in practice. Part 2: the patient experience. Circ Res. 2019;124:32–7. https://doi.org/10.1161/circresaha.118.314191.
Article
CAS
PubMed
Google Scholar
Naci H, Brugts J, Ades T. Comparative tolerability and harms of individual statins. A study-level network meta-analysis of 246 955 participants from 135 randomized controlled trials. Circ Cardiovasc Qual Outcomes. 2013;06:390–9.
Article
Google Scholar
Search Collaborative Group. SLCO1B1 variants and statin-induced myopathy-a genomic study. N Engl J Med. 2008;359:789–99.
Article
Google Scholar
Preiss D, Campbell RT, Murray HM, Ford I, Packard CJ, Sattard N, et al. The effect of statin therapy on heart failure events: a collaborative meta-analysis of unpublished for the SEARCH Collaborative Group. SLCO1B1 data from major randomized trials. Eur Heart J. 2015;36:1536–46.
Article
CAS
Google Scholar
Betteridge EJ, Carmena R. The diabetogenic action of statins. Mechanisms and clinical implications. Nat Rew Endocrinol. 2016;12:99–110.
Article
CAS
Google Scholar
Wang S, Cai R, Yuan Y, Varghese Z, Moorhead J, Ruan XZ, et al. Association between reductions in low-density lipoprotein cholesterol wit statins therapy and the risk of new-onset diabetes: a meta-analysis. Sci Rep. 2017;7:39982. https://doi.org/10.1038/srep39982.
Article
CAS
PubMed
PubMed Central
Google Scholar
Agarwala A, Kulkarni S, Maddox T. The association of statin therapy with incident diabetes: evidence, mechanisms, and recommendation. Curr Cardiol Rep. 2018;20:50. https://doi.org/10.1007/s11886-018-0995-6.
Article
CAS
PubMed
Google Scholar
Laakso M, Kuusisto J. Diabetes secondary to treatment with statins. Curr Dian Rep. 2017;10:2–10.
Google Scholar
Crandall JP, Mather K, Rajpathak SN, Goldberg RB, Watson K, Foo S, et al. Statin use and risk of developing diabetes: results from the Diabetes Prevention Program. BMJ Open Diab Res Care. 2017;5:e000438. https://doi.org/10.1136/bmjdrc-2017-000438.
Article
PubMed
Google Scholar
Cederberg H, Stančáková A, Yaluri N, Modi S, Kuusisto J, Laakso M. Increased risk of diabetes with statin treatment is associated with impaired insulin sensitivity and insulin secretion: a 6 year follow-up study of the METSIM cohort. Diabetologia. 2017. https://doi.org/10.1007/s00125-015-3528-5.
Article
Google Scholar
Schmidt AF, Swerdlow DI, Holmes MV, Patel RS, Fairhurst-Hunter Z, Lyall DM, et al. PCSK9 genetic variants and risk of type 2 diabetes: a mendelian randomisation study. Lancet Diabetes Endocrinol. 2017. https://doi.org/10.1016/S2213-8587(16)30396-5.
Article
PubMed
PubMed Central
Google Scholar
Ravnskov U, Diamond DM, Hama R, Hamazaki T, Hammarskjöld B, Hynes N, et al. Lack of an association or an inverse association between low-density-lipoprotein cholesterol and mortality in the elderly: a systematic review. BMJ Open. 2016;6(6):e010401. https://doi.org/10.1136/bmjopen-2015-010401.
Article
PubMed
PubMed Central
Google Scholar
Hippisley-Cox J, Coupland C. Unintended effects of statins in men and women in England and Wales: population based cohort study using the QResearch database. BMJ. 2010;340:c2197.
Article
Google Scholar
Rodriguez F, Maron DJ, Knowles JW, Viraniy SS, Lin S, Heidenreich PA. Association between intensity of statin therapy and mortality in patients with atherosclerotic cardiovascular disease. JAMA Cardiol. 2017;2(1):47–54.
Article
Google Scholar
Halter JB, Musi N, McFarland Horne F, Crandall JP, Goldberg A, Harkless L, et al. Diabetes and cardiovascular disease in older adults: current status and future directions. Diabetes. 2014;63:2578–89.
Article
CAS
Google Scholar
Goldfine A. Is it really time to reassess benefits and risks? N Engl J Med. 2012;366:1752–5.
Article
CAS
Google Scholar
Borracci RA. Fallibility of the ethics committees in medical research. Rev Argent Cardiol. 2016;84:606–9.
Google Scholar
Doval H. Changing the paradigm of primary care: behavioral interventions, subsidies and taxes to “change lifestyle”. Rev Argent Cardiol. 2018;86:361–5.
Article
Google Scholar