Boudina S, Abel ED. Diabetic cardiomyopathy revisited. Circulation. 2007;115(25):3213–23.
Article
PubMed
Google Scholar
Bendas A, Rothe U, Kiess W, Kapellen TM, Stange T, Manuwald U, Salzsieder E, Holl RW, Schoffer O, Stahl-Pehe A et al. Trends in incidence rates during 1999–2008 and prevalence in 2008 of childhood type 1 diabetes mellitus in GERMANY—model-based national estimates. PLoS One 2015;10(7):e0132716. doi:10.1371/journal.pone.0132716.
Article
PubMed Central
PubMed
Google Scholar
Cai L, Kang YJ. Cell death and diabetic cardiomyopathy. Cardiovasc Toxicol. 2003;3(3):219–28.
Article
CAS
PubMed
Google Scholar
Poirier P, Bogaty P, Philippon F, Garneau C, Fortin C, Dumesnil JG. Preclinical diabetic cardiomyopathy: relation of left ventricular diastolic dysfunction to cardiac autonomic neuropathy in men with uncomplicated well-controlled type 2 diabetes. Metabolism. 2003;52(8):1056–61.
Article
CAS
PubMed
Google Scholar
Liu ZW, Zhu HT, Chen KL, Dong X, Wei J, Qiu C, Xue JH. Protein kinase RNA-like endoplasmic reticulum kinase (PERK) signaling pathway plays a major role in reactive oxygen species (ROS)-mediated endoplasmic reticulum stress-induced apoptosis in diabetic cardiomyopathy. Cardiovasc Diabetol. 2013;12(158):1475–2840.
Google Scholar
Donath MY, Shoelson SE. Type 2 diabetes as an inflammatory disease. Nat Rev Immunol. 2011;11(2):98–107.
Article
CAS
PubMed
Google Scholar
Banerjee M, Saxena M. Interleukin-1 (IL-1) family of cytokines: role in type 2 diabetes. Clin Chim Acta. 2012;413(15–16):1163–70.
Article
CAS
PubMed
Google Scholar
Rhodes CJ. Type 2 diabetes-a matter of beta-cell life and death? Science. 2005;307(5708):380–4.
Article
CAS
PubMed
Google Scholar
Shen Y, Qin J, Bu P. Pathways involved in interleukin-1beta-mediated murine cardiomyocyte apoptosis. Tex Heart Inst J. 2015;42(2):109–16.
Article
PubMed Central
PubMed
Google Scholar
Harding HP, Ron D. Endoplasmic reticulum stress and the development of diabetes: a review. Diabetes. 2002;51(3):S455–61.
Article
CAS
PubMed
Google Scholar
Liu Z, Cai H, Zhu H, Toque H, Zhao N, Qiu C, Guan G, Dang Y, Wang J. Protein kinase RNA-like endoplasmic reticulum kinase (PERK)/calcineurin signaling is a novel pathway regulating intracellular calcium accumulation which might be involved in ventricular arrhythmias in diabetic cardiomyopathy. Cell Signal. 2014;26(12):2591–600.
Article
CAS
PubMed
Google Scholar
Xu J, Zhou Q, Xu W, Cai L. Endoplasmic reticulum stress and diabetic cardiomyopathy. Exp Diabetes Res. 2012;827971(10):24.
Google Scholar
Li Y, Guo Y, Tang J, Jiang J, Chen Z. New insights into the roles of CHOP-induced apoptosis in ER stress. Acta Biochim Biophys Sin. 2014;46(8):629–40.
Article
CAS
PubMed
Google Scholar
Benosman S, Ravanan P, Correa RG, Hou YC, Yu M, Gulen MF, Li X, Thomas J, Cuddy M, Matsuzawa Y et al: Interleukin-1 receptor-associated kinase-2 (IRAK2) is a critical mediator of endoplasmic reticulum (ER) stress signaling. PLoS One 2013; 8(5).
Li YL, Guo FK, Wu SG. Effects of antisense IRAK-2 oligonucleotides on PGI2 release induced by IL-1 and TNF. Acta Pharmacol Sin. 2000;21(7):646–8.
CAS
PubMed
Google Scholar
Dayer JM. Evidence for the biological modulation of IL-1 activity: the role of IL-1Ra. Clin Exp Rheumatol. 2002;20(5 Suppl 27):S14–20.
CAS
PubMed
Google Scholar
Deguine J, Barton GM. MyD88: a central player in innate immune signaling. F1000Prime Rep. 2014;6(97):6–97.
Google Scholar
Xu C, Shen J, Zhang J, Jia Z, He Z, Zhuang X, Xu T, Shi Y, Zhu S, Wu M, et al. Recombinant interleukin-1 receptor antagonist attenuates the severity of chronic pancreatitis induced by TNBS in rats. Biochem Pharmacol. 2015;93(4):449–60.
Article
CAS
PubMed
Google Scholar
Li Y, Zhang Y, Liu DB, Liu HY, Hou WG, Dong YS. Curcumin attenuates diabetic neuropathic pain by downregulating TNF-alpha in a rat model. Int J Med Sci. 2013;10(4):377–81.
Article
PubMed Central
CAS
PubMed
Google Scholar
Wu J, Yan LJ. Streptozotocin-induced type 1 diabetes in rodents as a model for studying mitochondrial mechanisms of diabetic beta cell glucotoxicity. Diabetes Metab Syndr Obes. 2015;8:181–8.
PubMed Central
PubMed
Google Scholar
Xu RS. Pathogenesis of diabetic cerebral vascular disease complication. World J Diabetes. 2015;6(1):54–66.
Article
PubMed Central
PubMed
Google Scholar
King H, Aubert RE, Herman WH. Global burden of diabetes, 1995–2025: prevalence, numerical estimates, and projections. Diabetes Care. 1998;21(9):1414–31.
Article
CAS
PubMed
Google Scholar
Lam CS. Diabetic cardiomyopathy: an expression of stage B heart failure with preserved ejection fraction. Diab Vasc Dis Res. 2015 (pii: 1479164115579006).
Lakshmanan AP, Harima M, Suzuki K, Soetikno V, Nagata M, Nakamura T, Takahashi T, Sone H, Kawachi H, Watanabe K. The hyperglycemia stimulated myocardial endoplasmic reticulum (ER) stress contributes to diabetic cardiomyopathy in the transgenic non-obese type 2 diabetic rats: a differential role of unfolded protein response (UPR) signaling proteins. Int J Biochem Cell Biol. 2013;45(2):438–47.
Article
CAS
PubMed
Google Scholar
Guo R, Liu W, Liu B, Zhang B, Li W, Xu Y. SIRT1 suppresses cardiomyocyte apoptosis in diabetic cardiomyopathy: an insight into endoplasmic reticulum stress response mechanism. Int J Cardiol. 2015;191:36–45.
Article
PubMed
Google Scholar
Cao SS, Luo KL, Shi L. Endoplasmic reticulum stress Interacts with inflammation in human diseases. J Cell Physiol. 2015;22(10):25098.
Google Scholar
Maritim AC, Sanders RA, Watkins JB 3rd. Diabetes, oxidative stress, and antioxidants: a review. J Biochem Mol Toxicol. 2003;17(1):24–38.
Article
CAS
PubMed
Google Scholar
Park SH, Park JH, Shim HM, Na AY, Bae KC, Lim JG, Song DK. Protection of pancreatic beta-cells against glucotoxicity by short-term treatment with GLP-1. Biochem Biophys Res Commun. 2015;459(4):561–7.
Article
CAS
PubMed
Google Scholar
Janikiewicz J, Hanzelka K, Kozinski K, Kolczynska K, Dobrzyn A. Islet beta-cell failure in type 2 diabetes—within the network of toxic lipids. Biochem Biophys Res Commun. 2015;3(15):153.
Google Scholar
Sivitz WI, Yorek MA. Mitochondrial dysfunction in diabetes: from molecular mechanisms to functional significance and therapeutic opportunities. Antioxid Redox Signal. 2010;12(4):537–77.
Article
PubMed Central
CAS
PubMed
Google Scholar
Luo B, Li B, Wang W, Liu X, Xia Y, Zhang C, Zhang Y, Zhang M, An F. Rosuvastatin alleviates diabetic cardiomyopathy by inhibiting NLRP3 inflammasome and MAPK pathways in a type 2 diabetes rat model. Cardiovasc Drugs Ther. 2014;28(1):33–43.
Article
CAS
PubMed
Google Scholar
Malozowski S, Sahlroot JT. Interleukin-1-receptor antagonist in type 2 diabetes mellitus. N Engl J Med. 2007;357(3):302–3 (author reply 303).
Article
CAS
PubMed
Google Scholar
Poitout V, Robertson RP. Minireview: secondary beta-cell failure in type 2 diabetes–a convergence of glucotoxicity and lipotoxicity. Endocrinology. 2002;143(2):339–42.
CAS
PubMed
Google Scholar
Costes S, Langen R, Gurlo T, Matveyenko AV, Butler PC. beta-Cell failure in type 2 diabetes: a case of asking too much of too few? Diabetes. 2013;62(2):327–35.
Article
PubMed Central
CAS
PubMed
Google Scholar
Masters SL, Dunne A, Subramanian SL, Hull RL, Tannahill GM, Sharp FA, Becker C, Franchi L, Yoshihara E, Chen Z, et al. Activation of the NLRP3 inflammasome by islet amyloid polypeptide provides a mechanism for enhanced IL-1beta in type 2 diabetes. Nat Immunol. 2010;11(10):897–904.
Article
PubMed Central
CAS
PubMed
Google Scholar
Vallejo S, Palacios E, Romacho T, Villalobos L, Peiro C, Sanchez-Ferrer CF. The interleukin-1 receptor antagonist anakinra improves endothelial dysfunction in streptozotocin-induced diabetic rats. Cardiovasc Diabetol. 2014;13(158):014–0158.
Google Scholar
Howard C, Noe A, Skerjanec A, Holzhauer B, Wernsing M, Ligueros-Saylan M, Thuren T. Safety and tolerability of canakinumab, an IL-1beta inhibitor, in type 2 diabetes mellitus patients: a pooled analysis of three randomised double-blind studies. Cardiovasc Diabetol. 2014;13(94):1475–2840.
Google Scholar
Cenni V, Sirri A, De Pol A, Maraldi NM, Marmiroli S. Interleukin-1-receptor-associated kinase 2 (IRAK2)-mediated interleukin-1-dependent nuclear factor kappaB transactivation in Saos2 cells requires the Akt/protein kinase B kinase. Biochem J. 2003;376(Pt 1):303–11.
Article
PubMed Central
CAS
PubMed
Google Scholar
Meng Q, Zheng M, Liu H, Song C, Zhang W, Yan J, Qin L, Liu X. TRAF6 regulates proliferation, apoptosis, and invasion of osteosarcoma cell. Mol Cell Biochem. 2012;371(1–2):177–86.
Article
CAS
PubMed
Google Scholar