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Table 5 Multivariable logistic regression analysis of independent determinants for plaque progression

From: Chromosome 9p21.3 polymorphism in a Chinese Han population is associated with angiographic coronary plaque progression in non-diabetic but not in type 2 diabetic patients

 

HR

95% CI

p

 

HR

95% CI

p

Non-diabetes

   

Diabetes

   

rs1333049 (GC vs. GG)

3.468

1.504-8.000

0.004

 

0.529

0.685-1.474

0.077

rs1333049 (CC vs. GG)

4.339

1.740-10.821

0.002

 

0.878

0.278-2.814

0.644

Gender (male vs. female)

2.912

1.184-7.161

0.020

 

1.807

1.615-3.100

0.007

Age (y)

0.993

0.914-1.025

0.051

 

0.932

0.876-0.995

0.027

Hypertension

2.129

1.066-4.251

0.032

 

2.287

0.840-6.223

0.105

Hyperlipidemia

2.110

0.732-4.148

0.324

 

6.057

1.922-22.145

0.003

Smoking

1.301

0.638-2.656

0.469

 

3.165

1.008-9.938

0.048

Triglyceride

0.880

0.601-1.298

0.886

 

1.130

0.580-2.119

0.720

Total cholesterol

0.531

0.247-1.429

0.528

 

0.431

0.254-1.116

0.077

LDL-C

1.422

0.497-2.104

0.701

 

1.749

0.556-2.599

0.378

HDL-C

0.471

0.106-0.877

0.030

 

0.214

0.005-0.915

0.037

Creatinine

1.104

0.975-1.156

0.226

 

1.009

0.989-1.029

0.361

Baseline hsCRP

1.302

1.115-1.522

<0.001

 

1.283

1.211-1.309

<0.001

Use of statins

1.401

0.644-3.492

0.562

 

1.709

0.590-4.952

0.317

BMI

1.028

0.925-1.143

0.608

 

1.025

0.889-1.181

0.734

  1. Abbreviations are as in Table 1.