Skip to main content

Table 4 Plaque progression in different genotypes of rs1333049

From: Chromosome 9p21.3 polymorphism in a Chinese Han population is associated with angiographic coronary plaque progression in non-diabetic but not in type 2 diabetic patients

Non-DM (N = 280)

GG (n = 90)

GC (n = 114)

CC (n = 76)

p

New coronary lesion

0.05 ± 0.22

0.07 ± 0.27

0.11 ± 0.32

0.347

Change of MLD (mm)

0.05 ± 0.35

0.20 ± 0.35 a

0.25 ± 0.49 b

0.005

Change of diameter stenosis (%)

-3.44 ± 13.80

-7.38 ± 13.70

-8.93 ± 14.64 a

0.038

Coronary artery score (mm)

0.01 ± 0.02

0.12 ± 0.04 a

0.16 ± 0.07 b

0.004

Cumulative coronary obstruction

-0.02 ± 0.11

-0.17 ± 0.09

-0.28 ± 0.13 a

0.025

DM (N = 150)

GG (n = 32)

GC (n = 86)

CC (n = 32)

 

New coronary lesion

0.19 ± 0.40

0.07 ± 0.23

0.13 ± 0.34

0.173

Change of MLD (mm)

0.34 ± 0.53

0.39 ± 0.53

0.46 ± 0.56

0.513

Change of diameter stenosis (%)

-9.20 ± 19.61

-10.86 ± 18.77

-10.67 ± 15.74

0.908

Coronary artery score (mm)

0.14 ± 0.07

0.22 ± 0.11

0.29 ± 0.15

0.152

Cumulative coronary obstruction

-0.05 ± 0.10

-0.25 ± 0.18

-0.36 ± 0.27

0.770

  1. MLD, minimal lumen diameter.
  2. a < 0.05 compared with GG
  3. b <0.01 compared with GG