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Table 3 Changes in biochemical and angiographic measurements during follow-up

From: Chromosome 9p21.3 polymorphism in a Chinese Han population is associated with angiographic coronary plaque progression in non-diabetic but not in type 2 diabetic patients

  Rs1333049  
  GG (n = 122) GC (n = 200) CC (n = 108) p
Change of Biochemical measurements  
   Total cholesterol (mmol/L) 0.64 ± 1.17 0.41 ± 1.12 0.53 ± 1.14 0.228
   LDL-C (mmol/L) 0.27 ± 0.98 0.24 ± 0.90 0.34 ± 0.86 0.623
   HDL-C (mmol/L) -0.05 ± 0.49 -0.01 ± 0.22 0.01 ± 0.19 a 0.422
   Triglyceride (mmol/L) 0.41 ± 1.92 0.10 ± 0.86 a 0.16 ± 1.06 b 0.106
   apoA (g/L) 0.10 ± 0.15 0.09 ± 0.17 0.08 ± 0.16 0.029
   apoB (g/L) 0.41 ± 0.37 0.39 ± 0.30 0.40 ± 0.34 0.639
   Lipoprotein (a) (g/L) -0.01 ± 0.08 -0.02 ± 0.09 -0.01 ± 0.12 0.873
   Fast glucose (mmol/L) 0.39 ± 1.22 0.42 ± 2.48 0.66 ± 1.58 0.487
   HbA1c (%) 0.52 ± 1.54 0.40 ± 1.32 0.27 ± 1.44 0.419
   White blood cells (× 10 9/L) 0.75 ± 2.02 0.92 ± 1.94 a 1.46 ± 1.87 a 0.012
   Neutrophile (× 10 9/L) 0.51 ± 1.64 0.66 ± 1.98 1.13 ± 1.80 a 0.025
   Lymphocyte (× 10 9/L) 0.21 ± 0.66 0.21 ± 0.64 0.29 ± 0.54 0.463
Smoking status     
   Non-smoker (%) 67 (54.9%) 109 (54.5%) 54 (49.2%) 0.309
   Smoker with cessation (%) 30 (24.6%) 49 (24.5%) 30 (27.7%) 0.474
   Smoker without cessation (%) 25 (20.5%) 42 (21.0%) 24 (23.1%) 0.532
Angiographic features     
   New coronary lesion 0.09 ± 0.29 0.07 ± 0.26 0.11 ± 0.32 0.385
   Change of MLD (mm) 0.18 ± 0.46 0.26 ± 0.44 0.29 ± 0.50 0.151
   Change of diameter stenosis (%) -5.14 ± 15.87 -8.82 ± 16.03 -9.38 ± 14.89 0.081
   Coronary artery score (mm) 0.05 ± 0.03 0.16 ± 0.07 0.21 ± 0.11 0.188
   Cumulative coronary obstruction -0.03 ± 0.09 -0.20 ± 0.13 -0.31 ± 0.21 0.076
  1. MLD, minimal lumen diameter; other abbreviations are listed in table 1
  2. a < 0.05 compared with GG
  3. b <0.01 compared with GG