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  2. The identification of circulating biomarkers associated with the risk of type 2 diabetes (T2D) is useful for improving the current prevention strategies in the most at-risk patients. Here, we aimed to investig...

    Authors: Mikaël Croyal, Matthieu Wargny, Kevin Chemello, Chloé Chevalier, Valentin Blanchard, Edith Bigot-Corbel, Gilles Lambert, Cédric Le May, Samy Hadjadj and Bertrand Cariou
    Citation: Cardiovascular Diabetology 2022 21:21
    Content type: Original investigation Published on:

  3. There is uncertainty and limited data regarding initiation of sodium-glucose cotransporter 2 (SGLT2) inhibitors among patients hospitalized with acute heart failure (AHF). This systematic review and meta-analy...

    Authors: Husam M. Salah, Subhi J. Al’Aref, Muhammad Shahzeb Khan, Malek Al-Hawwas, Srikanth Vallurupalli, Jawahar L. Mehta, J. Paul Mounsey, Stephen J. Greene, Darren K. McGuire, Renato D. Lopes and Marat Fudim
    Citation: Cardiovascular Diabetology 2022 21:20
    Content type: Original investigation Published on:

  4. Since sodium-glucose cotransporter 2 (SGLT2) inhibitors have a pleiotropic antiatherogenic effect, they are expected to attenuate the progression of atherosclerosis. However, whether SGLT2 inhibitors affect th...

    Authors: Naoto Katakami, Tomoya Mita, Norikazu Maeda, Yasunori Sato, Hirotaka Watada and Iichiro Shimomura
    Citation: Cardiovascular Diabetology 2022 21:19
    Content type: Original investigation Published on:

  5. The gut incretin hormones GLP-1 (glucagon-like peptide-1) and GIP (glucose-dependent insulinotropic peptide) are secreted by enteroendocrine cells following food intake leading to insulin secretion and glucose...

    Authors: Florian Kahles, Matthias Rau, Martin Reugels, Ann C. Foldenauer, Robert W. Mertens, Maria C. Arrivas, Jörg Schröder, Paul Idel, Julia Moellmann, Emiel P. C. van der Vorst, Nikolaus Marx and Michael Lehrke
    Citation: Cardiovascular Diabetology 2022 21:18
    Content type: Original investigation Published on:

  6. Elevated endothelial microparticles (EMPs) levels are surrogate markers of vascular dysfunction. We analyzed EMPs with apoptotic characteristics and assessed the angiogenic contents of microparticles in the bl...

    Authors: Isra Marei, Omar Chidiac, Binitha Thomas, Jennifer Pasquier, Soha Dargham, Amal Robay, Muneera Vakayil, Mohammad Jameesh, Christopher Triggle, Arash Rafii, Amin Jayyousi, Jassim Al Suwaidi and Charbel Abi Khalil
    Citation: Cardiovascular Diabetology 2022 21:17
    Content type: Original investigation Published on:

  7. It remains unclear how the variability of adiposity indices relates to incident HF. This study evaluated the associations of the variability in several adiposity indices with incident heart failure (HF) in ind...

    Authors: Arnaud D. Kaze, Sebhat Erqou, Prasanna Santhanam, Alain G. Bertoni, Rexford S. Ahima, Gregg C. Fonarow and Justin B. Echouffo-Tcheugui
    Citation: Cardiovascular Diabetology 2022 21:16
    Content type: Original investigation Published on:

  8. Diabetes have been known as a traditional risk factor of developing peripheral artery disease (PAD). However, the study evaluating the impact of long-term glycemic variability on the risk of developing PAD is ...

    Authors: Hye Soo Chung, Soon Young Hwang, Jung A. Kim, Eun Roh, Hye Jin Yoo, Sei Hyun Baik, Nan Hee Kim, Ji A. Seo, Sin Gon Kim, Nam Hoon Kim and Kyung Mook Choi
    Citation: Cardiovascular Diabetology 2022 21:15
    Content type: Original investigation Published on:

  9. Whether smoking modifies the associations of diabetes and risk factor management with subsequent risk of cardiovascular disease (CVD), and whether the smoking related CVD risk differs among people with and wit...

    Authors: Yang Yang, Nianchun Peng, Gang Chen, Qin Wan, Li Yan, Guixia Wang, Yingfen Qin, Zuojie Luo, Xulei Tang, Yanan Huo, Ruying Hu, Zhen Ye, Guijun Qin, Zhengnan Gao, Qing Su, Yiming Mu…
    Citation: Cardiovascular Diabetology 2022 21:14
    Content type: Original investigation Published on:

  10. HbA1c variability has emerged as risk factor for cardiovascular diseases in diabetes. However, the impact of HbA1c variability on cardiovascular diseases in subjects within the recommended HbA1c target has bee...

    Authors: Antonio Ceriello, Giuseppe Lucisano, Francesco Prattichizzo, Rosalba La Grotta, Stefan Franzén, Ann-Marie Svensson, Björn Eliasson and Antonio Nicolucci
    Citation: Cardiovascular Diabetology 2022 21:13
    Content type: Original investigation Published on:

  11. Guidelines recommend physical activity to reduce cardiovascular (CV) events. The association between physical activity and progression of chronic kidney disease (CKD) with and without diabetes is unknown. We a...

    Authors: Michael Böhm, Helmut Schumacher, Christian Werner, Koon K. Teo, Eva M. Lonn, Felix Mahfoud, Thimoteus Speer, Giuseppe Mancia, Josep Redon, Roland E. Schmieder, Karen Sliwa, Nikolaus Marx, Michael A. Weber, Ulrich Laufs, Bryan Williams, Salim Yusuf…
    Citation: Cardiovascular Diabetology 2022 21:12
    Content type: Original investigation Published on:

  12. It has been demonstrated that glycated albumin (GA) is significantly associated with diabetes complications and mortality. However, among patients diagnosed with non-ST-elevation acute coronary syndrome (NSTE-...

    Authors: Chi Liu, Qi Zhao, Xiaoteng Ma, Yujing Cheng, Yan Sun, Dai Zhang, Xiaoli Liu and Yujie Zhou
    Citation: Cardiovascular Diabetology 2022 21:11
    Content type: Original investigation Published on:

  13. Diabetes and hypertension are common in older adults and represent established risk factors for frailty. Frailty is a multidimensional condition due to reserve loss and susceptibility to stressors with a high ...

    Authors: Pasquale Mone, Jessica Gambardella, Angela Lombardi, Antonella Pansini, Stefano De Gennaro, Anna Luisa Leo, Michele Famiglietti, Anna Marro, Maria Morgante, Salvatore Frullone, Antonio De Luca and Gaetano Santulli
    Citation: Cardiovascular Diabetology 2022 21:10
    Content type: Original investigation Published on:

  14. Coronary artery ectasia (CAE) is a rare finding in coronary angiography and associated with poor clinical outcomes. Unlike atherosclerosis, diabetes mellitus (DM) is not commonly associated with CAE. This stud...

    Authors: Zhongxing Cai, Luqi Li, Haoyu Wang, Sheng Yuan, Dong Yin, Weihua Song and Kefei Dou
    Citation: Cardiovascular Diabetology 2022 21:9
    Content type: Original investigation Published on:

  15. To assess trends in primary and specialist care consultation rates and average length of consultation by cardiovascular disease (CVD), type 2 diabetes mellitus (T2DM), or cardiometabolic multimorbidity exposur...

    Authors: Sophia Abner, Clare L. Gillies, Sharmin Shabnam, Francesco Zaccardi, Samuel Seidu, Melanie J. Davies, Tobi Adeyemi, Kamlesh Khunti and David R. Webb
    Citation: Cardiovascular Diabetology 2022 21:8
    Content type: Original investigation Published on:

  16. Patients with diabetes are at increased risk of developing chronic limb-threatening ischemia (CLTI) due to peripheral arterial disease, and this often results in lower extremity amputation (LEA). Little is kno...

    Authors: Ariel Fangting Ying, Tjun Yip Tang, Aizhen Jin, Tze Tec Chong, Derek John Hausenloy and Woon-Puay Koh
    Citation: Cardiovascular Diabetology 2022 21:7
    Content type: Original investigation Published on:

  17. Fetuin-A is a hepatokine which has the capacity to prevent vascular calcification. Moreover, it is linked to the induction of metabolic dysfunction, insulin resistance and associated with increased risk of dia...

    Authors: Anna Birukov, Elli Polemiti, Susanne Jäger, Norbert Stefan and Matthias B. Schulze
    Citation: Cardiovascular Diabetology 2022 21:6
    Content type: Original investigation Published on:

  18. Systemic inflammatory processes plausibly contribute to the development of cardiovascular complications, causing increased morbidity and mortality in type 2 diabetes. Circulating inflammatory markers, i.e., in...

    Authors: A. M. Wegeberg, T. Okdahl, S. Riahi, N. Ejskjaer, F. Pociot, J. Størling, B. Brock and C. Brock
    Citation: Cardiovascular Diabetology 2022 21:5
    Content type: Original investigation Published on:

  19. In patients with type 2 diabetes (T2D) sodium-glucose cotransporter 2 (SGLT-2) inhibitors improve glycaemic control as well as cardiovascular and renal outcomes. Their effects on l-arginine (Arg) related risk mar...

    Authors: Arne Gessner, Anna Gemeinhardt, Agnes Bosch, Dennis Kannenkeril, Christian Staerk, Andreas Mayr, Martin F. Fromm, Roland E. Schmieder and Renke Maas
    Citation: Cardiovascular Diabetology 2022 21:4
    Content type: Original investigation Published on:

  20. With the advancement of the world population aging, more attention should be paid to the prognosis of elderly patients with acute coronary syndrome (ACS). Triglyceride-glucose (TyG) index is a reliable indicat...

    Authors: Yang Jiao, Yongkang Su, Jian Shen, Xiaoling Hou, Ying Li, Jihang Wang, Bing Liu, Dongfeng Qiu, Zhijun Sun, Yundai Chen, Qing Xi, Mingzhi Shen and Zhenhong Fu
    Citation: Cardiovascular Diabetology 2022 21:3
    Content type: Original investigation Published on:

  21. Previous studies suggested an elevated risk of venous thromboembolism (VTE) among patients with type 2 diabetes mellitus (T2DM), with a possible sex difference. The impact of glycemic control on the risk of VT...

    Authors: Sarah H. R. Charlier, Christian Meier, Susan S. Jick, Christoph R. Meier and Claudia Becker
    Citation: Cardiovascular Diabetology 2022 21:2
    Content type: Original investigation Published on:

  22. The effect of comorbid hypertension and type 2 diabetes mellitus (T2DM) on coronary artery plaques examined by coronary computed tomography angiography (CCTA) is not fully understood. We aimed to comprehensive...

    Authors: Yu Jiang, Yuan Li, Ke Shi, Jin Wang, Wen-Lei Qian, Wei-Feng Yan, Tong Pang and Zhi-Gang Yang
    Citation: Cardiovascular Diabetology 2022 21:1
    Content type: Original investigation Published on:

  23. Elevated blood pressure among adolescents has been shown to be associated with future adverse cardiovascular outcomes and early onset diabetes. Most data regarding systolic and diastolic blood pressure trends ...

    Authors: Boris Fishman, Yair Zloof, Omri Orr, Avishai M. Tsur, Ariel Furer, Ma’ayan Omer Gilon, Gabriel Chodick, Adi Leiba, Estela Derazne, Dorit Tzur, Arnon Afek, Ehud Grossman and Gilad Twig
    Citation: Cardiovascular Diabetology 2021 20:242
    Content type: Original investigation Published on:

  24. Insulin-treated patients with type 2 diabetes (T2D) are at risk of hypoglycemia, which is associated with an increased risk of cardiovascular disease and mortality. Using a long-term monitoring approach, we in...

    Authors: Andreas Andersen, Jonatan I. Bagger, Samuel K. Sørensen, Maria P. A. Baldassarre, Ulrik Pedersen-Bjergaard, Julie L. Forman, Gunnar Gislason, Tommi B. Lindhardt, Filip K. Knop and Tina Vilsbøll
    Citation: Cardiovascular Diabetology 2021 20:241
    Content type: Original investigation Published on:

  25. Post-stroke functional recovery is severely impaired by type 2 diabetes (T2D). This is an important clinical problem since T2D is one of the most common diseases. Because weight loss-based strategies have been...

    Authors: Dimitra Karampatsi, Alexander Zabala, Ulrika Wilhelmsson, Doortje Dekens, Ellen Vercalsteren, Martin Larsson, Thomas Nyström, Milos Pekny, Cesare Patrone and Vladimer Darsalia
    Citation: Cardiovascular Diabetology 2021 20:240
    Content type: Original investigation Published on:

  26. Evidence is limited regarding the association of healthy lifestyle including sleep pattern with the risk of complicated type 2 diabetes mellitus (T2DM) among patients with hypertension. We aimed to investigate...

    Authors: Zimin Song, Ruotong Yang, Wenxiu Wang, Ninghao Huang, Zhenhuang Zhuang, Yuting Han, Lu Qi, Ming Xu, Yi-da Tang and Tao Huang
    Citation: Cardiovascular Diabetology 2021 20:239
    Content type: Original investigation Published on:

  27. The enhanced thrombotic milieu in diabetes contributes to increased risk of vascular events. Aspirin, a key antiplatelet agent, has inconsistent effects on outcomes in diabetes and the best dosing regimen rema...

    Authors: William A. E. Parker, Rebecca Sagar, Zeyad Kurdee, Fladia Hawkins, Khalid M. Naseem, Peter J. Grant, Robert F. Storey and Ramzi A. Ajjan
    Citation: Cardiovascular Diabetology 2021 20:238
    Content type: Original investigation Published on:

  28. Treatment with glucagon-like peptide-1 receptor agonists (GLP-1 RAs) leads to multiple metabolic changes, reduction in glucose levels and body weight are well established. In people with type 2 diabetes, GLP-1...

    Authors: J. Jendle, T. Hyötyläinen, M. Orešič and T. Nyström
    Citation: Cardiovascular Diabetology 2021 20:237
    Content type: Original investigation Published on:

  29. It has been suggested that sodium–glucose cotransporter 2 (SGLT-2) inhibitors reduce the cardiorenal risk in patients with type 2 diabetes (T2D). The purpose of this study is to provide an update of all large ...

    Authors: Dario Giugliano, Miriam Longo, Lorenzo Scappaticcio, Giuseppe Bellastella, Maria Ida Maiorino and Katherine Esposito
    Citation: Cardiovascular Diabetology 2021 20:236
    Content type: Original investigation Published on:

  31. Intensive glycemic control is generally recommended for diabetic patients to reduce complications. However, the role of glycemic control in the mortality in diabetic patients with acute myocardial infarction (...

    Authors: Ik Jun Choi, Eun Ho Choo, Hwa Jung Kim, Sungmin Lim, Donggyu Moon, Kwan Yong Lee, Byung-Hee Hwang, Chan Joon Kim, Mahn-Won Park, Jong-Min Lee, Chul Soo Park, Hee-Yeol Kim, Ki-Dong Yoo, Doo Soo Jeon, Wook Sung Chung, Min Chul Kim…
    Citation: Cardiovascular Diabetology 2021 20:234
    Content type: Original investigation Published on:

  33. Low C-peptide levels, indicating beta-cell dysfunction, are associated with increased within-day glucose variation and hypoglycemia. In advanced type 2 diabetes, severe hypoglycemia and increased glucose varia...

    Authors: Juraj Koska, Daniel S. Nuyujukian, Gideon D. Bahn, Jin J. Zhou and Peter D. Reaven
    Citation: Cardiovascular Diabetology 2021 20:232
    Content type: Original investigation Published on:

  34. Incidence rates of cardiovascular disease (CVD) are increasing, partly driven by the diabetes epidemic. Novel prediction tools and modifiable treatment targets are needed to enhance risk assessment and managem...

    Authors: Parag Anilkumar Chevli, Barry I. Freedman, Fang-Chi Hsu, Jianzhao Xu, Megan E. Rudock, Lijun Ma, John S. Parks, Nicholette D. Palmer and Michael D. Shapiro
    Citation: Cardiovascular Diabetology 2021 20:231
    Content type: Original investigation Published on:

  35. Atrial fibrillation (AF) is a common arrhythmia classified as paroxysmal and non-paroxysmal. Non-paroxysmal AF is associated with an increased risk of complications. Diabetes contributes to AF initiation, yet ...

    Authors: Fadi Alijla, Chepkoech Buttia, Tobias Reichlin, Salman Razvi, Beatrice Minder, Matthias Wilhelm, Taulant Muka, Oscar H. Franco and Arjola Bano
    Citation: Cardiovascular Diabetology 2021 20:230
    Content type: Review Published on:

  36. The THEMIS randomized trial compared ticagrelor plus aspirin versus placebo plus aspirin for patients with stable coronary artery disease and type 2 diabetes mellitus (CAD-T2DM), and without prior myocardial i...

    Authors: Patrick Blin, Patrice Darmon, Patrick Henry, Estelle Guiard, Marie-Agnès Bernard, Caroline Dureau-Pournin, Hélène Maizi, Florence Thomas-Delecourt, Régis Lassalle, Cécile Droz-Perroteau and Nicholas Moore
    Citation: Cardiovascular Diabetology 2021 20:229
    Content type: Original investigation Published on:

  37. Dyslipidemia is a major cardiovascular risk factor and common in diabetes patients. Most guidelines focus on optimal lipid levels, while variation of lipid profiles is far less discussed. This study aims to in...

    Authors: Mu-Cyun Wang, Chia-Ing Li, Chiu-Shong Liu, Chih-Hsueh Lin, Shing-Yu Yang, Tsai-Chung Li and Cheng-Chieh Lin
    Citation: Cardiovascular Diabetology 2021 20:228
    Content type: Original investigation Published on:

  38. Dysglycaemia is associated with overall cardiovascular disease even at prediabetes levels. The aim of this study was to explore the association between glucose levels and future risk of developing atrial fibri...

    Authors: Viktor Lind, Niklas Hammar, Pia Lundman, Leif Friberg, Mats Talbäck, Göran Walldius and Anna Norhammar
    Citation: Cardiovascular Diabetology 2021 20:227
    Content type: Original investigation Published on:

  39. Atrial fibrillation (AF) is prevalent in patients with type 2 diabetes mellitus (T2DM). Obesity commonly accompanies T2DM, and increases the risk of AF. However, the dose-relationship between body mass index (...

    Authors: Jung-Chi Hsu, Yen-Yun Yang, Shu-Lin Chuang, Yi-Wei Chung, Chih-Hsien Wang and Lian-Yu Lin
    Citation: Cardiovascular Diabetology 2021 20:226
    Content type: Original investigation Published on:

  40. Incretin hormones are peptides released in the intestine in response to the presence of nutrients in its lumen. The main incretins are glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polyp...

    Authors: Enrique Z. Fisman and Alexander Tenenbaum
    Citation: Cardiovascular Diabetology 2021 20:225
    Content type: Commentary Published on:

  41. Epicardial adipose tissue (EAT) is considered a novel diagnostic marker for cardiometabolic disease. This study aimed to evaluate whether EAT volume was associated with stress-induced myocardial ischemia in as...

    Authors: Emmanuel Cosson, Minh Tuan Nguyen, Imen Rezgani, Narimane Berkane, Sara Pinto, Hélène Bihan, Sopio Tatulashvili, Malak Taher, Meriem Sal, Michael Soussan, Pierre-Yves Brillet and Paul Valensi
    Citation: Cardiovascular Diabetology 2021 20:224
    Content type: Original investigation Published on:

  42. Biomarkers may contribute to improved cardiovascular risk estimation. Glycated hemoglobin A1c (HbA1c) is used to monitor the quality of diabetes treatment. Its strength of association with cardiovascular outcomes...

    Authors: Christoph Sinning, Nataliya Makarova, Henry Völzke, Renate B. Schnabel, Francisco Ojeda, Marcus Dörr, Stephan B. Felix, Wolfgang Koenig, Annette Peters, Wolfgang Rathmann, Ben Schöttker, Hermann Brenner, Giovanni Veronesi, Giancarlo Cesana, Paolo Brambilla, Tarja Palosaari…
    Citation: Cardiovascular Diabetology 2021 20:223
    Content type: Original investigation Published on:

  43. We aimed to compare cardiovascular outcomes of patients with type 2 diabetes (T2D) who initiated GLP-1 receptor agonists (GLP-1RA) or basal insulin (BI) under routine care.

    Authors: Enrico Longato, Barbara Di Camillo, Giovanni Sparacino, Lara Tramontan, Angelo Avogaro and Gian Paolo Fadini
    Citation: Cardiovascular Diabetology 2021 20:222
    Content type: Original investigation Published on:

  44. RBP4 is an adipokine with an established role in atherosclerosis, while adiponectin has unique anti-inflammatory properties. We investigated the association of RBP4 and adiponectin with the presence of symptom...

    Authors: Nikolaos P. E. Kadoglou, Emmanouil Korakas, Christos Karkos, Eirini Maratou, Ioannis Kanonidis, Panagiotis Plotas, Nikolaos Papanas, Paraskevi Moutsatsou, Ignatios Ikonomidis and Vaia Lambadiari
    Citation: Cardiovascular Diabetology 2021 20:221
    Content type: Original investigation Published on:

  45. Type 2 diabetes is a condition associated with a state of low-grade inflammation caused by adipose tissue dysfunction and insulin resistance. High sensitive-CRP (hs-CRP) is a marker for systemic low-grade infl...

    Authors: Shahnam Sharif, Y. Van der Graaf, M. J. Cramer, L. J. Kapelle, G. J. de Borst, Frank L. J. Visseren and Jan Westerink
    Citation: Cardiovascular Diabetology 2021 20:220
    Content type: Original investigation Published on:

  46. Recent studies indicated that sodium glucose cotransporter (SGLT)2 inhibition increases levels of ketone bodies in the blood in patients with type 1 and 2 diabetes. Other studies suggested that in patients wit...

    Authors: R. Pietschner, J. Kolwelter, A. Bosch, K. Striepe, S. Jung, D. Kannenkeril, C. Ott, M. Schiffer, S. Achenbach and R. E. Schmieder
    Citation: Cardiovascular Diabetology 2021 20:219
    Content type: Original investigation Published on:

  47. Type 2 diabetes is one of the most relevant risk factors for heart failure, the prevalence of which is increasing worldwide. The aim of the review is to highlight the current perspectives of the pathophysiolog...

    Authors: Antonio Ceriello, Doina Catrinoiu, Chanchal Chandramouli, Francesco Cosentino, Annique Cornelia Dombrowsky, Baruch Itzhak, Nebojsa Malić Lalic, Francesco Prattichizzo, Oliver Schnell, Petar M. Seferović, Paul Valensi and Eberhard Standl
    Citation: Cardiovascular Diabetology 2021 20:218
    Content type: Review Published on:

  48. Diabetes is associated with adverse outcomes after percutaneous coronary intervention with drug-eluting stents (DES), but for prediabetes this association has not been definitely established. Furthermore, in p...

    Authors: Eline H. Ploumen, Tineke H. Pinxterhuis, Paolo Zocca, Ariel Roguin, Rutger L. Anthonio, Carl E. Schotborgh, Edouard Benit, Adel Aminian, Peter W. Danse, Carine J. M. Doggen, Clemens von Birgelen and Marlies M. Kok
    Citation: Cardiovascular Diabetology 2021 20:217
    Content type: Original investigation Published on:

  49. Authors: Michal Herman-Edelstein, Tali Guetta, Amir Barnea, Maayan Waldman, Naomi Ben-Dor, Yaron D. Barac, Ran Kornowski, Michael Arad, Edith Hochhauser and Dan Aravot
    Citation: Cardiovascular Diabetology 2021 20:216
    Content type: Correction Published on:

    The original article was published in Cardiovascular Diabetology 2021 20:90

  50. Type 2 diabetes mellitus (T2DM) is a major risk factor for coronary artery disease and myocardial infarction (MI). The interaction of diabetic cardiomyopathy and MI scars on myocardial deformation in T2DM pati...

    Authors: Yue Gao, Hua-yan Xu, Ying-kun Guo, Xiao-ling Wen, Rui Shi, Yuan Li and Zhi-gang Yang
    Citation: Cardiovascular Diabetology 2021 20:215
    Content type: Original investigation Published on:
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