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Table 3 Association of insulin resistance index with new onset hypertension phenotype

From: Prediction of various insulin resistance indices for the risk of hypertension among military young adults: the CHIEF cohort study, 2014–2020

Incidence of total hypertension

 

Isolated systolic hypertension

 

Isolated diastolic hypertension

 

Combined hypertension

HR (95% CI)

p-value

 

HR (95% CI)

p-value

 

HR (95% CI)

p-value

TyG index

0.835 (0.663–1.052)

0.12

 

1.355 (1.121–1.637)

0.002

 

1.056 (0.799–1.396)

0.70

TG/HDL-C

0.975 (0.915–1.040)

0.44

 

1.060 (1.025–1.096)

0.001

 

1.012 (0.942–1.087)

0.75

METS-IR

0.634 (0.326–1.233)

0.18

 

3.006 (1.747–5.171)

< 0.001

 

1.624 (0.716–3.683)

0.24

ZJU index

0.995 (0.985–1.005)

0.30

 

1.005 (1.000–1.010)

0.04

 

1.005 (0.997–1.013)

0.23

Incidence of stage I hypertension

TyG index

0.826 (0.653–1.046)

0.11

 

1.376 (1.123–1.687)

0.002

 

0.828 (0.575–1.193)

0.31

TG/HDL-C

0.975 (0.913–1.041)

0.44

 

1.082 (1.039–1.127)

< 0.001

 

0.964 (0.873–1.065)

0.46

METS-IR

0.619 (0.313–1.221)

0.16

 

3.455 (1.921–6.214)

< 0.001

 

1.196 (0.425–3.366)

0.73

ZJU index

0.995 (0.984–1.005)

0.31

 

1.005 (0.999–1.011)

0.09

 

0.995 (0.980–1.009)

0.47

Incidence of stage II hypertension

TyG index

1.643 (0.892–3.027)

0.11

 

1.265 (0.825–1.939)

0.28

 

2.821 (1.244–6.395)

0.01

TG/HDL-C

1.074 (0.931–1.240)

0.32

 

1.049 (0.974–1.130)

0.20

 

1.161 (0.963–1.398)

0.11

METS-IR

4.216 (0.689–25.80)

0.11

 

2.179 (0.622–7.628)

0.22

 

6.940 (0.617–78.10)

0.11

ZJU index

1.013 (1.003–1.023)

0.009

 

1.011 (1.001–1.021)

0.03

 

1.010 (0.982–1.038)

0.49

  1. Data are presented as hazard ratios (HR) and 95% confidence intervals (CI) using multivariable Cox regression analysis for age, sex, alcohol intake, tobacco smoking, family history for early-onset cardiovascular diseases or hypertension, body mass index, physical activity levels, systolic blood pressure, diastolic blood pressure, low-density lipoprotein cholesterol, serum uric acid, blood urea nitrogen and estimated glomerular filtration rate adjustments
  2. Abbreviations: TyG, triglyceride glucose; TG, triglyceride; HDL-C, high-density lipoprotein cholesterol; METS-IR, metabolic score for insulin resistance; ZJU, Zhejiang University