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Table 2 Logistic regression models for the association of cardiometabolic biomarkers with diabetic kidney disease

From: Associations between cardiometabolic indices and the risk of diabetic kidney disease in patients with type 2 diabetes

 

AIP

 

SHR

 

TyG index

 

HOMA-IR

 

OR

95% CI

P value

 

OR

95% CI

P value

 

OR

95% CI

P value

 

OR

95% CI

P value

Model 1

               

per unit increase

1.09

1.06–1.12

< 0.001

 

1.46

1.14–1.88

0.003

 

1.79

1.64–1.95

< 0.001

 

1.07

1.05–1.09

< 0.001

Tertile 1

Reference

 

Reference

 

Reference

 

Reference

Tertile 2

1.31

1.10–1.56

0.003

 

0.84

0.71-1.00

0.048

 

1.20

1.00-1.45

0.054

 

1.60

1.25–2.05

< 0.001

Tertile 3

2.17

1.83–2.57

< 0.001

 

1.30

1.11–1.51

0.001

 

2.60

2.19–3.10

< 0.001

 

2.95

2.32–3.75

< 0.001

P for trend

  

< 0.001

   

0.005

   

0.004

   

< 0.001

Model 2

               

per unit increase

1.09

1.05–1.13

< 0.001

 

1.60

1.13–2.27

0.008

 

1.70

1.50–1.93

< 0.001

 

1.04

1.02–1.07

0.001

Tertile 1

Reference

 

Reference

 

Reference

 

Reference

Tertile 2

0.98

0.76–1.25

0.855

 

0.98

0.76–1.25

0.855

 

1.01

0.76–1.34

0.949

 

1.27

0.88–1.84

0.206

Tertile 3

1.59

1.22–2.08

0.001

 

1.30

1.03–1.64

0.028

 

2.00

1.53–2.61

< 0.001

 

2.47

1.70–3.59

< 0.001

P for trend

  

0.002

   

0.003

   

0.006

   

0.005

Model 3

               

per unit increase

1.08

1.04–1.12

< 0.001

 

1.63

1.14–2.32

0.007

 

1.62

1.43–1.84

< 0.001

 

1.03

1.01–1.06

0.009

Tertile 1

Reference

 

Reference

 

Reference

 

Reference

Tertile 2

1.00

0.95–1.06

0.968

 

1.15

0.89–1.48

0.295

 

1.01

0.76–1.35

0.944

 

1.25

0.86–1.81

0.252

Tertile 3

1.08

1.02–1.14

0.005

 

1.42

1.12–1.81

0.004

 

1.86

1.42–2.45

< 0.001

 

2.24

1.52–3.30

< 0.001

P for trend

  

0.014

   

0.012

   

0.009

   

0.023

  1. AIP, atherogenic index of plasma; CI, confidence interval; HOMA-IR, homeostasis model assessment of insulin resistance; OR, odds ratio; SHR, stress hyperglycemia ratio; TyG, triglyceride-glucose