Table 2 Associations between triglyceride-glucose index and incident cardiovascular disease stratified by systolic blood pressure
TyG | Overall (N = 6558) | SBP < 120mmHg (N = 2434) | SBP = 120-129mmHg (N = 1324) | SBP ≥ 130mmHg (N = 2800) | Relative HR with SBP group increment | P-interaction | ||||
|---|---|---|---|---|---|---|---|---|---|---|
Incidence rate & 95% CI (Per 1000 person-years) | HR (95% CI) | Incidence rate & 95% CI (Per 1000 person-years) | HR (95% CI) | Incidence rate & 95% CI (Per 1000 person-years) | HR (95% CI) | Incidence rate & 95% CI (Per 1000 person-years) | HR (95% CI) | |||
Per 1-SD increment | 27.4 (26.1, 28.8) | 1.19 (1.12, 1.27) | 21.8 (19.9, 23.9) | 1.31 (1.17, 1.47) | 28.3 (25.4, 31.5) | 1.28 (1.12, 1.47) | 31.9 (29.7, 34.2) | 1.10 (1.01, 1.20) | 0.91 (0.86, 0.96) | < 0.001 |
Q1[< 8.21] | 17.3 (15.3, 19.6) | Reference | 13.4 (10.9, 16.5) | Reference | 17.9 (13.8, 23.3) | Reference | 22.4 (18.6, 27.1) | Reference | Reference | < 0.001 |
Q2[8.21 ∼ 8.58] | 24.7 (22.2, 27.3) | 1.29 (1.10, 1.52) | 18.9 (15.7, 22.7) | 1.32 (0.99, 1.75) | 25.8 (20.6, 32.3) | 1.32 (0.92, 1.88) | 30.1 (25.9, 35.0) | 1.23 (0.96, 1.58) | 0.96 (0.88, 1.04) | |
Q3[8.58 ∼ 9.02] | 30.7 (28.0, 33.7) | 1.48 (1.25, 1.74) | 25.4 (21.4, 30.3) | 1.63 (1.22, 2.18) | 32.7 (26.7, 40.1) | 1.63 (1.14, 2.32) | 33.7 (29.6, 38.3) | 1.28 (1.00, 1.63) | 0.87 (0.77, 0.98) | |
Q4[> 9.02] | 37.1 (34.1, 40.4) | 1.54 (1.29, 1.84) | 35.5 (30.2, 41.7) | 2.09 (1.53, 2.87) | 37.9 (31.4, 45.7) | 1.62 (1.09, 2.41) | 37.7 (33.6, 42.4) | 1.23 (0.95, 1.60) | 0.76 (0.65, 0.89) | |
P-trend | - | < 0.001 | - | < 0.001 | - | 0.010 | - | 0.184 | - | - |