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Table 2 All-cause and atherosclerotic cardiovascular mortality in individuals with type 2 diabetes versus controls

From: Risk factors for and risk of all-cause and atherosclerotic cardiovascular disease mortality in people with type 2 diabetes and peripheral artery disease: an observational, register-based cohort study

Group

No. of Events

Person-Years

Incidence Rate per 10 000 Person-Years (95% CI)

Hazard Ratio

(95% CI)*

P-Value

P < 0.05 = †

All-cause mortality

     

Controls, no PAD

116 414

3 681 164

316.2

(314.4–318.1)

Reference

 

T2D, no PAD

60 558

1 539 673

393.3

(390.2–396.5)

1.11

(1.09–1.13)†

P < 0.05

Controls with PAD

3 935

71 661

549.1 (532.1–566.5)

Reference

 

T2D with PAD

3 804

63 361

600.4 (581.4–619.8)

1.12

(1.05–1.19)†

P < 0.05

Cardiovascular mortality

     

Controls, no PAD

69 637

3 681 164

189.2 (187.8–190.6)

Reference

 

T2D, no PAD

39 885

1 539 673

259.1 (256.5–261.6)

1.09

(1.08–1.10)†

P < 0.05

Controls with PAD

2 971

71 661

414.6 (399.8–429.8)

Reference

 

T2D with PAD

2 959

63 361

467 (450.3–484.1)

1.13

(1.07–1.19)†

P < 0.05

  1. Number of events, incidence rates and adjusted hazard ratios for mortality (all-cause and atherosclerotic cardiovascular disease mortality) in individuals with type 2 diabetes versus controls, stratified by whether onset of incident peripheral artery disease occurred or not
  2. *Based on Cox regression analysis adjusted for age, sex, diabetes duration, all demographic and socioeconomic variables, selected medications and comorbidities shown in Table 1
  3. †Significant difference versus controls (P < 0.05)
  4. CI indicates confidence interval; PAD, peripheral artery disease; and T2D, type 2 diabetes mellitus