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Table 4 Cox regression analysis to assess mortality

From: Factors influencing hospitalization or emergency department visits and mortality in type 2 diabetes following the onset of new cardiovascular diagnoses in a population-based study

  

Hazard

95.0% CI for Exp(B)

 
  

ratio

Lower

Upper

p-value

Origin of diagnosis

     

IPC

Reference

1.00

   

OPC

 

0.37

0.20

0.67

< 0.001

Primary care

 

0.34

0.18

0.66

< 0.001

Emergency department

 

0.56

0.25

1.26

0.16

Sex and age

     

Women

 

1.08

0.75

1.56

0.67

Age

 

1.05

1.03

1.08

< 0.001

Systolic blood pressure

     

< 100 mmHg

Reference

1.00

   

100–130 mmHg

 

0.38

0.19

0.77

0.02

> 130 mmHg

 

0.26

0.13

0.52

< 0.001

Glucose regulation

     

P-Glucose > 8,5 mmol/ml

Reference

1.00

   

P-Glucose  8,5 mmol/ml

 

0.91

0.62

1.31

0.60

HbA1c < 52 mmol/mol

Reference

1.00

   

HbA1c 52–70 mmol/mol

 

1.49

1.07

2.56

0.02

HbA1c > 70 mmol/mol

 

1.46

1.18

3.82

0.01

Kidney function

     

eGFR > 60 ml/min

Reference

1.00

   

eGFR 30–59 ml/min

 

1.49

0.86

2.56

0.36

eGFR < 30 ml/min

 

1.49

0.86

2.59

0.15

LDL-Cholesterol

     

LDL < 2,5 mmol/ml

Reference

1.00

   

LDL  2.5 mmol/ml

 

1.46

1.01

2.11

0.04

Pharmacotherapy

     

Insulin

 

0.80

0.52

1.22

0.30

Metformin

 

0.41

0.28

0.62

< 0.001

DPP4

 

0.85

0.55

1.32

0.47

GLP1

 

0.96

0.54

1.73

0.90

SGLT2

 

0.20

0.06

0.64

0.01

Aldosterone antagonist

 

0.80

0.52

1.24

0.32

Betablocker

 

0.97

0.66

1.44

0.89

Calcium antagonist

 

0.70

0.48

1.01

0.06

RAASi

 

0.74

0.51

1.07

0.11

Statin

 

0.39

0.27

0.57

< 0.001

Follow-up visit

     

Hospital outpatient care > 30 days

Reference

1.00

   

Hospital outpatient care  30 days

 

0.79

0.38

1.64

0.53

Primary care > 30 days

Reference

1.00

   

Primary care  30 days

 

0.53

0.37

0.77

< 0.001

  1. Note CI = confidence interval, IPC = in-patient care (hospitalization), OPC = out-patient care in hospital setting, HbA1c = hemoglobin A1c, LDL-cholesterol = Low-density lipoprotein cholesterol, eGFR = estimated glomerulofiltration rate, GLP1 = Glucagon-like peptide-1 agonists, DPP4 = dipeptidyl peptidase 4 inhibitors, SGLT-2 = sodium-glucose cotransporter-2 inhibitors, RAASi = Renin-angiotensin-aldosterone system inhibitors