Table 3 Cox regression analysis to assess hospital admissions/emergency department visits

Diagnose origin

IPC

Reference

1.00

OPC

0.89

0.68

1.16

0.06

Primary care

0.52

0.35

0.77

< 0.001

Emergency department

1.23

0.78

1.94

0.80

Sex and age

Women

0.88

0.72

1.07

0.20

Age

1.02

1.00

1.03

0.01

Systolic blood pressure

< 100 mm Hg

Reference

1.00

100–130 mmHg

0.61

0.32

1.14

0.31

> 130 mm Hg

0.54

0.29

1.00

0.21

Renal function

eGFR > 60 ml/min

Reference

1.00

eGFR 30–60 ml/min

0.87

0.69

1.09

0.30

eGFR < 30 ml/min

0.85

0.58

1.24

0.40

Glucose regulation

HbA1c < 52 mmol/ml

Reference

1.00

HbA1c 52–70 mmol/ml

0.85

0.69

1.05

0.43

HbA1c > 70 mmol/ml

0.76

0.54

1.07

0.90

LDL-cholesterol ≥ 2.5 mmol/ml

1.00

LDL-cholesterol < 2.5 mmol/ml

1.05

0.84

1.32

0.67

Pharmacotherapy

Insulin

1.29

1.04

1.61

0.02

Metformin

0.88

0.70

1.10

0.25

DPP4

1.38

1.10

1.74

0.006

GLP1

1.04

0.78

1.38

0.81

SGLT2

1.01

0.77

1.34

0.93

Aldosterone antagonist

1.63

1.27

2.08

< 0.001

Betablocker

1.34

1.08

1.67

0.008

Calcium blocker

1.21

0.99

1.47

0.06

RAASi

1.01

0.80

1.26

0.95

Statin

0.97

0.71

1.32

0.82

Healthcare utilization

Hospital out-patient care visit > 30 days

Reference

1.00

Hospital out-patient care visit ≤ 30 days

2.19

1.70

2.82

< 0.001

Primary care visit > 30 days

Reference

1.00

Primary care visit ≤ 30 days

0.86

0.70

1.05

0.13