Fig. 3From: Sodium-glucose cotransporter 2 inhibitors, inflammation, and heart failure: a two-sample Mendelian randomization studyThe CXCL10 mediated the causal effect of SGLT-2 inhibitor on heart failure. The β1 value between the SGLT-2 inhibitor and inflammation biomarker and the β2 value between inflammation biomarker and heart failure are MR estimates using the inverse–variance weighted methodBack to article page