Fig. 1From: Sodium-glucose cotransporter 2 inhibitors, inflammation, and heart failure: a two-sample Mendelian randomization studyThe flowchart of two-sample and two-step mendelian randomization evaluating the effects of inflammation biomarkers in mediating the effect of SGLT-2 inhibition on heart failure. HbA1c glycated hemoglobin, GWAS genome-wide association study, pQTL protein quantitative trait loci SNP single nucleotide polymorphism, LD linkage disequilibrium, CRP C-reactive protein, SGLT-2 sodium-glucose Cotransporter-2Back to article page