Associations of triglyceride-glucose (TyG) index with chest pain incidence and mortality among the U.S. population

Table 3 HRs (95% CIs) for all-cause mortality according to the TyG index

Characteristic	model 1			model 2			model 3
Characteristic	HR¹	95% CI¹	P-value	HR¹	95% CI¹	P-value	HR¹	95% CI¹	P-value
All participants
Continous	1.29	1.21, 1.37	< 0.001	1.19	1.08, 1.30	< 0.001	1.21	1.09, 1.33	< 0.001
TyG index
Q1	—	—		—	—		—	—
Q2	1.35	1.14, 1.60	< 0.001	0.98	0.84, 1.14	0.8	1.01	0.86, 1.18	> 0.9
Q3	1.48	1.26, 1.73	< 0.001	1.03	0.90, 1.18	0.7	1.05	0.91, 1.21	0.5
Q4	1.64	1.42, 1.89	< 0.001	1.18	1.02, 1.36	0.021	1.19	1.03, 1.37	0.021
P for trend			< 0.001			< 0.001			< 0.001
Pain
Continous	1.18	1.02, 1.36	0.029	1.13	0.96, 1.34	0.13	1.14	0.94, 1.37	0.2
TyG index
Q1	—	—		—	—		—	—
Q2	1.14	0.82, 1.58	0.4	0.90	0.64, 1.26	0.5	0.90	0.65, 1.27	0.6
Q3	1.22	0.92, 1.61	0.2	0.88	0.67, 1.16	0.4	0.88	0.67, 1.15	0.3
Q4	1.45	1.09, 1.94	0.010	1.12	0.85, 1.48	0.4	1.13	0.84, 1.50	0.4
P for trend			0.065			0.065			0.065
No pain
Continous	1.33	1.21, 1.46	< 0.001	1.20	1.05, 1.37	0.007	1.25	1.09, 1.43	0.002
TyG index
Q1	—	—		—	—		—	—
Q2	1.45	1.14, 1.83	0.002	1.02	0.83, 1.25	0.9	1.06	0.86, 1.32	0.6
Q3	1.60	1.27, 2.01	< 0.001	1.10	0.90, 1.35	0.4	1.15	0.93, 1.42	0.2
Q4	1.68	1.33, 2.13	< 0.001	1.18	0.94, 1.49	0.2	1.22	0.96, 1.54	0.10
P for trend			< 0.001			< 0.001			< 0.001

HR = Hazard Ratio, CI = Confidence Interval
Model 1: Unadjusted
Model 2: Adjusted for age, sex, and BMI
Model 3: Adjusted for age, sex, BMI, race, education, smoking status, total cholesterol, hypertension, heart failure, coronary heart disease, angina, heart attack, stroke, antihyperlipidemic agents, and antidiabetic agents

ISSN: 1475-2840