Table 1 General baseline characteristics of study participants
Characteristics | Total (n = 403) | T2DM (n = 207) | Non-T2DM (n = 196) | P value |
|---|---|---|---|---|
Age (years) | 54.0 (12.0) | 53.2 (15.0) | 53.5 (10.0) | 0.62 |
Males, n (%) | 235 (58.3) | 126 (60.9) | 109 (55.6) | 0.17 |
Smoking status, n (%) | 0.54 | |||
Never smoking | 253 (62.8) | 130 (62.8) | 123 (62.8) | |
Smoking | 150 (37.2) | 77 (37.3) | 73 (37.2) | |
BMI (kg/m²) | 24.2 (4.7) | 24.9 (4.7) | 24.6 (4.2) | 0.85 |
SBP (mmHg) | 119.0 (14.0) | 117.1 (12.3) | 118.6 (14.0) | 0.07 |
DBP (mmHg) | 75.0 (8.0) | 75.6 (9.0) | 74.4 (7.0) | 0.07 |
TC (mM) | 5.0 (1.5) | 4.8 (1.5) | 5.0 (1.4) | 0.08 |
TG (mM) | 1.7 (1.2) | 2.2 (1.4) | 1.7 (0.8) | < 0.01 |
HDL-c (mM) | 1.1 (0.4) | 1.1 (0.3) | 1.3 (0.4) | < 0.01 |
LDL-c (mM) | 2.8 (1.0) | 2.8 (1.1) | 2.9 (1.0) | 0.09 |
FBG (mM) | 5.6 (4.1) | 9.9 (4.1) | 5.1 (0.5) | < 0.01 |
HbA1c (%) | 6.0 (3.6) | 8.9 (3.7) | 5.4 (0.4) | < 0.01 |
25- (OH)D3 (ng/ml) | 16.0 (6.4) | 15.6 (7.5) | 17.4 (5.0) | 0.01 |
Scr (mM) | 57.0 (20.2) | 55.4 (19.7) | 63.4 (21.9) | < 0.01 |
BUN (mM) | 4.9 (1.7) | 5.5 (1.8) | 4.6 (1.3) | < 0.01 |
Cys-C (mM) | 0.81 (0.2) | 0.90 (0.2) | 0.80 (0.2) | < 0.01 |
Ca (mM) | 2.34 (0.11) | 2.34 (0.13) | 2.36 (0.12) | 0.02 |
P (mM) | 1.2 (0.3) | 1.1 (0.2) | 1.4 (0.4) | < 0.01 |
eGFR (ml/min/1.73m2) | 101.5 (19.7) | 99.6 (22.6) | 101.3 (18.7) | 0.40 |
FGF23 (pg/ml) | 353.3 (246.2) | 451.7 (192.6) | 308.4 (195.3) | < 0.01 |
α-klotho (ng/ml) | 2.5 (3.2) | 2.8 (2.3) | 3.6 (3.5) | < 0.01 |