Table 1 Baseline characteristics of subjects with type 1, type 2 diabetes, prediabetes and normoglycemia
From: Lipidome characterisation and sex-specific differences in type 1 and type 2 diabetes mellitus
Control | Prediabetes | T1D | T2D | P-value | |
|---|---|---|---|---|---|
N = 100 | N = 69 | N = 59 | N = 86 | ||
Sex (men) | 60 (60.0%) | 34 (49.3%) | 27 (45.8%) | 46 (53.5%) | 0.308 |
Age (years) | 53.1 (12.3) | 56.7 (11.9) | 50.7 (9.9) | 58.0 (10.0) | < 0.001 |
Hypertension (yes) | 17 (17.0%) | 19 (27.5%) | 22 (37.3%) | 48 (55.8%) | < 0.001 |
Dyslipidemia (yes) | 26 (26.0%) | 30 (43.5%) | 30 (50.8%) | 49 (57.0%) | < 0.001 |
BMI (kg/m2) | 25.7 (3.6) | 27.8 (4.2) | 25.5 (3.6) | 31.7 (5.6) | < 0.001 |
Waist circumference (cm) | 94.5 (11.7) | 99.3 (11.4) | 89.1 (12.2) | 106 (12.4) | < 0.001 |
DM duration (years) | . | . | 24.6 (10.4) | 10.6 (7.7) | < 0.001 |
HbA1c (%) | 5.26 (0.28) | 5.73 (0.31) | 7.58 (0.94) | 8.16 (1.54) | < 0.001 |
Glucose (mg/dL) | 88.0 (7.1) | 95.3 (9.5) | 154.0 (79.4) | 169.0 (61.2) | < 0.001 |
Smoking (former/current) | 41 (41.0%) | 42 (60.9%) | 31 (52.5%) | 52 (60.5%) | 0.024 |
sBP (mmHg) | 122 (15) | 129 (14) | 130 (19) | 139 (18) | < 0.001 |
dBP (mmHg) | 77 (10) | 80 (9) | 71 (10) | 77 (11) | < 0.001 |
TG (mg/dL) | 105.0 (50.6) | 124.0 (58.3) | 68.9 (38.1) | 127.0 (65.8) | < 0.001 |
HDL-cholesterol (mg/dL) | 58.0 (15.2) | 56.3 (11.3) | 65.5 (16.8) | 49.0 (12.7) | < 0.001 |
LDL-cholesterol (mg/dL) | 128.0 (29.2) | 127.0 (31.1) | 102.0 (20.2) | 103.0 (33.8) | < 0.001 |
Insulin (yes) | 0 (0.0%) | 0 (0.0%) | 59 (100%) | 31 (36.0%) | < 0.001 |
Metformin (yes) | 0 (0.0%) | 0 (0.0%) | 0 (0.0%) | 68 (79.1%) | < 0.001 |
aMED | 3.38 (1.81) | 3.07 (1.59) | 4.36 (1.61) | 4.19 (1.51) | < 0.001 |
eGFR (mL/min/1.73 m2) | 87.2 (14.9) | 83.6 (18.3) | 91.7 (14.3) | 89.8 (19.2) | 0.033 |