Fig. 2

Fold-change values and statistical significance obtained for each lipid determined as being significantly different in at least one of the nine analyses conducted. Statistical significance is indicated using asterisks: corrected p-value (p) < 0.05 (*), p < 0.01 (**), p < 0.001 (***), p < 0.0001 (****). Bars in the right side of each panel indicate a positive fold-change value, while bars in the left indicate a negative one. A positive fold-change indicates that the lipid is increased in the first group (e.g. in T1D vs. T2D, TG(18:1_18:1_18:2) is significantly increased in T1D with respect to T2D). The different colours in the background of the plot show the different lipid classes. In the left, the names of the lipid subspecies are shown. The nomenclatures of the type 16:1e indicate that the fatty acid (FA) of the glycerophospholipid is linked to the glycerol moiety by an ether bond, therefore, the mentioned glycerophospholipid is an ether-glycerophospholipid