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Table 1 Clinical profile, cardiovascular risk factors and therapies characterizing the subgroup of CAD patients enrolled on the study. Patients have been categorized for the presence of T2DM as a comorbidity

From: Persistent epigenetic signals propel a senescence-associated secretory phenotype and trained innate immunity in CD34+ hematopoietic stem cells from diabetic patients

 

CAD

CAD-T2DM

P value

N

15

17

 

 AGE (years)

65.33 ± 2.41

66.88 ± 2.31

0.65

 BMI (KG/m2)

26.86 ± 0.87

27.13 ± 0.79

0.82

 Glycemia (mg/dL)

103.1 ± 3.27

137.5 ± 10.31

0.004**

 LDL (mg/dL)

120.4 ± 11.52

78.40 ± 9.74

0.0095**

 HDL (mg/dL)

48.93 ± 3.58

45.60 ± 3.29

0.49

 Total cholesterol (mg/dL)

189.1 ± 12.38

150.0 ± 9.67

0.012*

 Creatinin(mg/dL)

1.068 ± 0.1

1.096 ± 0.1

0.84

 Hypertension

11

15

 

 Dyslipidemia

11

15

 

 Smoke

7

6

 

 Oral antidiabetic agents

0

14

 

 Insulin

0

1

 

 Oral antidiabetic agents + Insulin

0

2

 

 Antihypertensive drugs

12

15

 

 Lipid-lowering drugs

7

13

 
  1. CAD ± T2DM, coronary artery disease with or without diabetes mellitus; BMI, body mass index; HDL, high-density lipoprotein; LDL, low-density lipoprotein. *P<0.05; **P<0.01 vs CAD