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Table 1 Baseline characteristics of included participants

From: The neutrophil-to-lymphocyte ratio is associated with all-cause and cardiovascular mortality among individuals with hypertension

Characteristics

Total

(n = 3067)

Lower NLR

(n = 2686)

Higher NLR

(n = 381)

P-value

Age, years

57.1 (56.4, 57.7)

56.3 (55.6, 56.9)

62.5 (60.8, 64.3)

< 0.0001

Sex, %

   

0.8896

 Male

48.4 (46.5, 50.3)

48.3 (46.1, 50.6)

48.9 (42.1, 55.6)

 

 Female

51.6 (49.7, 53.5)

51.7 (49.4, 53.9)

51.1 (44.4, 57.9)

 

Race, %

   

< 0.0001

 Non-Hispanic White

69.6 (64.8, 74.0)

67.9 (63.0, 72.4)

81.4 (75.1, 86.3)

 

 Non-Hispanic Black

14.5 (11.9, 17.5)

15.8 (13.0, 19.1)

5.2 (3.4, 8.0)

 

 Mexican American

5.6 (4.0, 7.8)

5.9 (4.2, 8.1)

3.8 (2.1, 6.6)

 

 Others

10.3 (8.6, 12.3)

10.4 (8.6, 12.5)

9.7 (6.7, 13.7)

 

Education levels, %

   

0.9317

 Less than high school level

6.7 (5.7, 7.8)

6.7 (5.7, 8.0)

6.2 (4.2, 9.1)

 

 High school or equivalent

37.2 (34.3, 40.3)

37.3 (34.2, 40.5)

36.9 (30.7, 43.5)

 

 Greater than high school level

56.1 (53.1, 59.1)

56.0 (52.7, 59.2)

56.9 (50.7, 63.0)

 

 Not recorded

0.0 (0.0, 0.1)

0.0 (0.0, 0.1)

0.1 (0.0, 0.4)

 

Smoking status, %

   

0.0216

 Never

49.4 (46.7, 52.1)

50.5 (47.7, 53.2)

41.9 (35.7, 48.5)

 

 Former

32.5 (29.9, 35.2)

31.3 (28.7, 34.0)

40.7 (33.0, 48.8)

 

 Current

18.1 (16.2, 20.2)

18.2 (16.3, 20.3)

17.4 (12.0, 24.5)

 

 Not recorded

0.3 (0.2, 0.6)

0.4 (0.2, 0.7)

0.0 (0.0, 0.0)

 

BMI, kg/m2

31.3 (30.9, 31.7)

31.4 (31.0, 31.8)

30.7 (29.5, 31.9)

0.246

BMI category, %

   

0.0009

 < 25

17.9 (16.1, 19.8)

16.9 (15.3, 18.7)

24.6 (19.3, 30.8)

 

 25–30

31.4 (29.5, 33.4)

31.8 (29.6, 34.0)

29.2 (23.4, 35.7)

 

 ≥ 30

50.7 (48.3, 53.0)

51.3 (49.0, 53.6)

46.2 (38.9, 53.7)

 

 Not recorded

1.1 (0.7, 1.6)

0.9 (0.6, 1.4)

2.4 (1.4, 4.2)

 

Diabetes, %

   

0.0334

 No

81.0 (79.0, 82.9)

81.8 (79.5, 83.9)

75.6 (69.5, 80.7)

 

 Yes

19.0 (17.1, 21.0)

18.2 (16.1, 20.5)

24.4 (19.3, 30.5)

 

 Not recorded

0.0 (0.0, 0.2)

0.0 (0.0, 0.2)

0.0 (0.0, 0.0)

 

History of CVD, %

   

< 0.0001

 No

82.6 (80.9, 84.2)

84.7 (83.2, 86.1)

68.2 (61.2, 74.5)

 

 Yes

17.4 (15.8, 19.1)

15.3 (13.9, 16.8)

31.8 (25.5, 38.8)

 

 Not recorded

0.4 (0.2, 0.7)

0.4 (0.3, 0.8)

0.1 (0.0, 1.0)

 

HbA1c, %

5.9 (5.9, 6.0)

5.9 (5.8, 6.0)

6.0 (5.8, 6.1)

0.4054

HDL, mg/dl

52.5 (51.6, 53.4)

52.6 (51.6, 53.5)

51.6 (49.6, 53.6)

0.3599

TC, mg/dl

195.2 (193.1, 197.4)

196.7 (194.2,199.1)

185.3 (179.3, 191.2)

0.0016

TG, mg/dl

143.0 (136.8, 149.1)

144.8 (137.8, 151.7)

130.6 (122.8, 138.5)

0.0088

LDL, mg/dl

114.7 (112.9, 116.4)

115.7 (113.9, 117.6)

107.4 (102.0, 112.8)

0.0072

SCR, mg/dl

1.0 (0.9, 1.0)

0.9 (0.9, 0.9)

1.1 (1.0, 1.3)

0.0025

Lymphocyte, × 109/L

2.0 (1.9, 2.0)

2.1 (2.0, 2.1)

1.3 (1.3, 1.4)

< 0.0001

Neutrophil, × 109/L

4.2 (4.1, 4.3)

3.9 (3.8, 4.0)

6.2 (5.9, 6.5)

< 0.0001

eGFR, mL/min/1.73m2

83.4 (82.3, 84.5)

84.5 (83.2, 85.8)

75.7 (72.8, 78.6)

< 0.0001

  1. BMI: body mass index; CVD: cardiovascular disease; HDL: high-density lipoprotein cholesterol; LDL: low-density lipoprotein cholesterol; TC: total cholesterol; TG: triglyceride; SCR: serum creatinine; eGFR: estimated glomerular filtration rate. Continuous variables are presented as the mean and 95% confidence interval, category variables are described as the percentage and 95% confidence interval. Continuous variables are presented as the mean and 95% confidence interval, category variables are described as the percentage and 95% confidence interval
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Cardiovascular Diabetology

ISSN: 1475-2840