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Fig. 4 | Cardiovascular Diabetology

Fig. 4

From: Protective effects of imeglimin on the development of atherosclerosis in ApoE KO mice treated with STZ

Fig. 4

a Urinary 8-OHdG levels were significantly higher in untreated DM group (control group) compared to non-DM group. And in imeglimin-treated DM group, urinary 8-OHdG levels were significantly lower compared to untreated DM group (control group). n = 4–6. b–d Expression levels of NLRP-3, IL-1β and MCP-1 mRNA were significantly higher in control group compared to non-DM group. NLRP-3 and IL-1β levels were significantly lower in imeglimin group compared to control group. n = 8–10. *: p < 0.05

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Cardiovascular Diabetology

ISSN: 1475-2840