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Fig. 3 | Cardiovascular Diabetology

Fig. 3

From: Protective effects of imeglimin on the development of atherosclerosis in ApoE KO mice treated with STZ

Fig. 3

a–c In HE staining of the thoracic aorta, substantial plaque development was observed in untreated DM mice (control group) compared to non-DM mice. In imeglimin-treated DM mice, plaque development was markedly reduced compared to control group. d–f In CD68 staining of the aortic aorta, quite large CD68 positive area was observed in control group compared to non-DM group. In addition, CD68 positive area coincided with the plaque area. In imeglimin-treated DM mice, CD68 positive area was markedly reduced compared to control group

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Cardiovascular Diabetology

ISSN: 1475-2840