Fig. 3

Postprandial (iAUC) TAG and CE content expressed as percentages of total lipoprotein lipid content in muscle and liver IR. Left: associations of MISI with plasma metabolite iAUCs. Middle: associations of HIRI with plasma metabolite iAUCs. Right: plasma metabolite iAUCs in muscle compared to liver IR. Associations between MISI/HIRI and plasma metabolites were tested using linear regression analyses with adjustment for age, sex, center, BMI, waist-to-hip ratio, and HIRI/MISI. Differences between muscle and liver IR were tested using ANCOVA with adjustment for age, sex, center, BMI, and waist-to-hip ratio. P-values were adjusted for a false discovery rate (FDR) of 0.05 using the Benjamini Hochberg method