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Table 2 Association of the TyG index with atherosclerotic stenosis in intracranial, extracranial, and combined intra/extracranial arteries

From: Association between triglyceride-glucose index and intracranial/extracranial atherosclerotic stenosis: findings from a retrospective study

 

Model 1*OR (95% CI)

p

Model 2 OR (95% CI)

p

Model 3# OR (95% CI)

p

Model 4& OR (95% CI)

p

Intracranial stenosis (n = 396)

  

TyG index

1.45(1.07–1.98)

0.017

1.48(1.09–2.03)

0.013

1.44(1.05–1.98)

0.025

1.77 (1.10–2.84)

0.019

TyG index tertiles

T1 (n = 126)

reference

 

reference

 

reference

 

reference

 

T2 (n = 132)

1.42(0.90–2.24)

0.132

1.44(0.91–2.28)

0.116

1.42(0.89–2.26)

0.139

1.37(0.84–2.23)

0.211

T3 (n = 138)

1.81(1.12–2.90)

0.015

1.87(1.16–3.01)

0.011

1.80(1.11–2.94)

0.018

1.88(1.01–1.86)

0.046

p for trend

1.35(1.06–1.71)

0.014

1.37(1.08–1.74)

0.010

1.35(1.06–1.72)

0.017

1.37(1.01–1.86)

0.044

Extracranial stenosis (n = 222)

  

TyG index

1.03(0.74–1.43)

0.872

1.22(0.86–1.73)

0.260

1.20(0.84–1.71)

0.323

1.45(0.86–2.45)

0.166

TyG index tertiles

T1 (n = 93)

reference

 

reference

 

reference

 

reference

 

T2 (n = 71)

1.03(0.63–1.70)

0.892

1.19(0.70–2.02)

0.516

1.13(0.66–1.93)

0.651

1.13(0.64-2.00)

0.674

T3 (n = 58)

1.03(0.61–1.74)

0.917

1.37(0.78–2.41)

0.272

1.34(0.75–2.37)

0.321

1.50(0.73–3.07)

0.273

p for trend

1.02(0.78–1.32)

0.907

1.17(0.89–1.55)

0.265

1.15(0.87–1.53)

0.322

1.21(0.85–1.73)

0.287

Combined intra/extracranial stenosis (n = 368)

  

TyG index

1.86 (1.34–2.58)

< 0.001

2.47 (1.72–3.54)

< 0.001

2.37 (1.64–3.43)

< 0.001

2.81(1.67–4.72)

< 0.001

TyG index tertiles

T1 (n = 96)

reference

 

reference

 

reference

 

reference

 

T2 (n = 128)

1.81 (1.13–2.88)

0.013

2.47 (1.49–4.11)

< 0.001

2.37 (1.42–3.98)

0.001

1.96(1.13–3.38)

0.017

T3 (n = 144)

2.47 (1.53–4.01)

< 0.001

3.83 (2.26–6.51)

< 0.001

3.68 (2.14–6.34)

< 0.001

3.27(1.66–6.46)

0.001

p for trend

1.58 (1.24–2.02)

< 0.001

1.97 (1.50–2.57)

< 0.001

1.93 (1.46–2.54)

< 0.001

1.82(1.29–2.56)

0.001

  1. TyG index Triglyceride-glucose index
  2. T1, T2, T3 indicate the 1st, 2nd, and 3rd tertile of TyG
  3. * Model 1: Non adjusted
  4. Model 2: adjusted for age and sex
  5. # Model 3: adjusted for age, sex, smoking, drinking, medical history of hypertension, stroke
  6. &Model 4: adjusted for age, sex, smoking, drinking, medical history of hypertension, stroke, platelet, TC, HDL, and LDL