The relative and combined ability of stress hyperglycemia ratio and N-terminal pro-B-type natriuretic peptide to predict all-cause mortality in diabetic patients with multivessel coronary artery disease

Table 3 Associations of SHR and NT-proBNP categories with all-cause mortality

Variable	Events, n/Total	Unadjusted model		Adjusted model
Variable	Events, n/Total	HR (95%CI)	P value	HR (95%CI)	P value
SHR			< 0.001
Low	46/574(8.0)	Reference		Reference
High	92/574(16.0)	2.072(1.454–2.952)		2.046(1.414–2.960)	< 0.001
NT-proBNP			< 0.001
Low	36/574(6.3)	Reference		Reference
High	102/574(17.7)	3.021(2.066–4.418)		5.739(3.365–9.789)	< 0.001
Combined categories			< 0.001		< 0.001
G1(SHR-L + NT-proBNP-L)	11/282(3.9)	References		References
G2(SHR-H + NT-proBNP-L)	25/292(8.6)	2.225(1.095–4.522)	0.027	2.372(1.160–4.849)	0.018
G3(SHR-L + NT-proBNP-H)	35/292(12.0)	3.204(1.627–6.308)	0.001	6.587(3.012–14.406)	< 0.001
G4(SHR-H + NT-proBNP-H)	67/282(23.8)	6.753(3.569–12.778)	< 0.001	12.244(5.828–25.721)	< 0.001

SHR stress hyperglycemia, NT-proBNP N-terminal proB-type natriuretic peptide, HR hazard ratio; CI confidential intervals. Adjusted variables included age, smoker, hypertension, previous MI, previous stroke, ACS, LVEF, hemoglobin, TC, TG, HDL-C, LDL-C, hs-CRP, creatinine, three-vessel disease, left main disease, aspirin, and statin

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