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Table 2 Independent associates of CAN category in FDS2 participants with type 2 diabetes

From: Prevalence and prognostic significance of cardiac autonomic neuropathy in community-based people with type 2 diabetes: the Fremantle Diabetes Study Phase II

 

Possible CAN

Definite CAN

OR (95% CI)

OR (95% CI)

Aboriginal descent

1.91 (1.01, 3.62)

1.65 (0.72, 3.78)

Diabetes duration (increase of 1 year)

1.01 (0.98, 1.03)

1.05 (1.02, 1.08)

Body mass index (increase of 1 kg/m2)

1.02 (0.99, 1.05)

1.04 (1.005, 1.08)

Pulse rate (increase of 1 beat/min)

1.01 (0.996, 1.03)

1.04 (1.02, 1.06)

On beta-blockers

1.95 (1.24, 3.09)

2.86 (1.60, 4.93)

On calcium channel blockers

1.70 (1.15, 2.50)

2.44 (1.47, 4.04)

On antidepressant medication

1.67 (1.06, 2.64)

2.81 (1.60, 4.93)

Ln [urinary albumin:creatinine ratio (mg/mmol)]a

1.09 (0.95, 1.24)

1.29 (1.10, 1.53)

Distal symmetrical polyneuropathy

1.12 (0.79, 1.58)

1.65 (1.04, 2.61)

Prior hospitalisation for heart failure

2.96 (1.11, 7.92)

3.46 (1.15, 10.4)

  1. Multinomial regression was used with no prevalent CAN as the reference. Data are odds ratios (OR) and 95% confidence intervals (CIs). Values are provided for both CAN categories where variables were significant for at least category
  2. aA 2.72-fold increase in urinary albumin:creatinine ratio corresponds to an increased risk of 1 in ln(urinary albumin:creatinine)