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Table 3 Mean adjusted levels of cardiovascular risk factors in the 3 weight change groups at 1-year, 3-years, and 5-years postpartum, respectively, after adjustment for age, ethnicity, family history of DM, parity, pre-pregnancy BMI, duration of breastfeeding, and time since delivery

From: Postpartum weight retention and the early evolution of cardiovascular risk over the first 5 years after pregnancy

   

Weight Loss

 

Weight Gain 0–6%

 

Weight Gain ≥6%

  

Cardiovascular Risk Factor

(n = 100)

 

(n = 110)

 

(n = 120)

 

P

Triglycerides (mmol/l):

       

 At 1-year

 

0.90 ± 0.05

1.00 ± 0.05

0.98 ± 0.05

0.2

 At 3-years

 

0.84 ± 0.04

0.92 ± 0.04

0.98 ± 0.04 a

0.02

 At 5-years

 

0.90 ± 0.05

1.05 ± 0.05 b

1.11 ± 0.05 a

0.001

HDL cholesterol (mmol/l):

       

 At 1-year

 

1.45 ± 0.04

1.48 ± 0.04

1.42 ± 0.04

0.44

 At 3-years

 

1.44 ± 0.04

1.46 ± 0.04

1.41 ± 0.04

0.51

 At 5-years

 

1.61 ± 0.05

1.62 ± 0.05

1.49 ± 0.04 c

0.02

LDL cholesterol (mmol/l):

       

 At 1-year

 

2.56 ± 0.10

2.67 ± 0.10

2.69 ± 0.09

0.47

 At 3-years

 

2.42 ± 0.10

2.55 ± 0.10

2.56 ± 0.08

0.36

 At 5-years

 

2.26 ± 0.10

2.48 ± 0.09

2.59 ± 0.08 a

0.01

apoB (g/L):

        

 At 1-year

 

0.78 ± 0.03

0.82 ± 0.02

0.81 ± 0.02

0.47

 At 3-years

 

0.72 ± 0.02

0.77 ± 0.02

0.77 ± 0.02

0.13

 At 5-years

 

0.74 ± 0.03

0.82 ± 0.03b

0.84 ± 0.02a

0.003

Matsuda index:

        

 At 1-year

 

6.86 ± 0.48

6.85 ± 0.47

6.92 ± 0.43

0.99

 At 3-years

 

6.96 ± 0.44

6.02 ± 0.38

5.26 ± 0.29 a

0.0006

 At 5-years

 

7.28 ± 0.49

6.02 ± 0.38 b

5.06 ± 0.29 a,c

< 0.0001

HOMA-IR:

        

 At 1-year

 

1.37 ± 0.09

1.35 ± 0.09

1.38 ± 0.08

0.95

 At 3-years

 

1.34 ± 0.09

1.59 ± 0.10

1.75 ± 0.10 a

0.002

 At 5-years

 

1.21 ± 0.08

1.44 ± 0.09

1.81 ± 0.10 a,c

< 0.0001

Fasting glucose (mmol/l):

       

 At 1-year

 

4.70 ± 0.06

4.78 ± 0.06

4.83 ± 0.05

0.18

 At 3-years

 

4.64 ± 0.06

4.73 ± 0.06

4.84 ± 0.05 a

0.01

 At 5-years

 

4.63 ± 0.07

4.74 ± 0.07

4.82 ± 0.06

0.07

CRP (mg/L):

        

 At 1-year

 

1.01 ± 0.14

1.10 ± 0.15

1.21 ± 0.15

0.55

 At 3-years

 

0.82 ± 0.11

1.01 ± 0.14

1.27 ± 0.15 a

0.02

 At 5-years

 

0.77 ± 0.12

1.04 ± 0.16

1.34 ± 0.18 a

0.01

  1. Bold indicates p < 0.05
adenotes P < 0.05 for weight gain ≥ 6.0% vs. weight loss;bdenotes P < 0.05 for weight gain 0–6% vs. weight loss;cdenotes P < 0.05 for weight gain ≥ 6.0% vs. weight gain 0–6%