Table 3 Results of Poisson models for people with and without diabetes, Augsburg, MONICA/KORA study region, 1985–2016

Model 1a (population with diabetes)

Time period^a

1989–1992

0.99 (0.82–1.20)

1.03 (0.76–1.39)

0.97 (0.79–1.19)

1993–1996

1.00 (0.82–1.20)

1.06 (0.79–1.44)

0.91 (0.74–1.13)

1997–2000

1.19 (1.002–1.44)*

1.35 (1.01–1.81)*

0.99 (0.80–1.22)

2001–2004

1.04 (0.87–1.25)

1.20 (0.91–1.60)

0.84 (0.68–1.04)

2005–2008

0.85 (0.71–1.03)

1.00 (0.75–1.33)

0.66 (0.53–0.82)*

2009–2012

0.81 (0.67–0.97)*

0.95 (0.72–1.26)

0.60 (0.48–0.75)*

2013–2016

0.63 (0.52–0.77)*

0.72 (0.54–0.97)*

0.52 (0.41–0.65)*

Male vs. female

1.88 (1.71–2.07)*

Age (years) ^b

65–74

3.45 (2.98–3.99)*

3.54 (2.90–4.31)*

2.59 (2.08–3.22)*

55–64

1.79 (1.53–2.08)*

1.92 (1.56–2.36)*

1.23 (0.97–1.56)

Model 1b (population without diabetes)

Time period^a

1989–1992

0.97 (0.87–1.09)

0.91 (0.83-0.9997)*

1.16 (0.99–1.35)

1993–1996

0.81 (0.73–0.91)*

0.75 (0.68–0.83)*

1.00 (0.85–1.17)

1997–2000

0.78 (0.70–0.87)*

0.74 (0.68–0.81)*

0.90 (0.77–1.06)

2001–2004

0.77 (0.69–0.86)*

0.74 (0.67–0.81)*

0.87 (0.74–1.03)

2005–2008

0.69 (0.61–0.77)*

0.65 (0.60–0.72)*

0.80 (0.67–0.94)*

2009–2012

0.67 (0.60–0.75)*

0.62 (0.57–0.69)*

0.83 (0.71–0.98)*

2013–2016

0.65 (0.58–0.73)*

0.62 (0.57–0.69)*

0.74 (0.62–0.87)*

Male vs. female

3.24 (3.04–3.45)*

Age (years) ^b

65–74

4.07 (3.78–4.38)*

3.41 (3.20–3.62)*

6.97 (6.17–7.89)*

55–64

2.06 (1.91–2.23)*

1.97 (1.85–2.10)*

2.53 (2.21–2.90)*

Models - stratified for time period^c

Diabetes (yes vs. no)

1985–1988

1.95 (1.62–2.34)*

1.40 (1.22–1.61)*

3.33 (2.84–3.91)*

1989–1992

2.01 (1.70–2.37)*

1.61 (1.33–1.96)*

2.87 (2.34–3.52)*

1993–1996

2.37 (2.04–2.75)*

2.00 (1.72–2.33)*

3.14 (2.49–3.95)*

1997–2000

2.93 (2.55–3.38)*

2.60 (2.26–2.99)*

3.71 (3.19–4.33)*

2001–2004

2.61 (2.24–3.03)*

2.33 (2.03–2.67)*

3.35 (2.61–4.29)*

2005–2008

2.46 (2.13–2.84)*

2.24 (1.91–2.63)*

3.07 (2.42–3.91)*

2009–2012

2.42 (2.09–2.80)*

2.33 (2.00-2.71)*

2.72 (2.08–3.56)*

2013–2016

1.92 (1.63–2.27)*

1.75 (1.47–2.09)*

2.57 (2.03–3.25)*

First non-fatal MI

              Relative risk for first non-fatal MI (95% CI)^d

Both sexes

Men

Women

Model 1a (population with diabetes)

Time period^a

1989–1992

0.86 (0.68–1.09)

0.87 (0.62–1.22)

0.86 (0.63–1.17)

1993–1996

0.92 (0.73–1.15)

0.92 (0.66–1.27)

0.92 (0.68–1.24)

1997–2000

1.23 (0.99–1.53)

1.46 (1.08–1.98)*

0.85 (0.62–1.17)

2001–2004

1.41 (1.15–1.73)*

1.54 (1.15–2.05)*

1.22 (0.92–1.62)

2005–2008

1.28 (1.04–1.57)*

1.41 (1.05–1.88)*

1.09 (0.82–1.43)

2009–2012

1.23 (1.01–1.51)*

1.42 (1.07–1.88)*

0.92 (0.69–1.23)

2013–2016

0.98 (0.79–1.20)

1.09 (0.81–1.46)

0.79 (0.59–1.07)

Male vs. female

2.02 (1.82–2.24)*

Age (years)^b

65–74

2.26 (1.96–2.61)*

2.29 (1.91–2.75)*

1.83 (1.41–2.36)*

55–64

1.49 (1.28–1.73)*

1.57 (1.30–1.89)*

1.11 (0.84–1.46)

Model 1b (population without diabetes)

Time period^a

1989–1992

0.96 (0.84–1.09)

0.87 (0.78–0.97)*

1.28 (1.03–1.58)*

1993–1996

0.82 (0.72–0.93)*

0.76 (0.68–0.85)*

1.07 (0.86–1.33)

1997–2000

0.77 (0.68–0.88)*

0.73 (0.65–0.82)*

0.94 (0.75–1.17)

2001–2004

0.96 (0.85–1.08)

0.88 (0.79–0.98)*

1.29 (1.05–1.59)*

2005–2008

0.91 (0.81–1.03)

0.84 (0.76–0.94)*

1.22 (0.99–1.51)

2009–2012

0.88 (0.78–0.99)*

0.79 (0.71–0.88)*

1.26 (1.03–1.55)*

2013–2016

0.90 (0.80–1.02)

0.83 (0.75–0.92)*

1.19 (0.96–1.46)

Male vs. female

3.59 (3.34–3.85)*

Age (years) ^b

65–74

2.99 (2.77–3.23)*

2.53 (2.37–2.71)*

5.10 (4.44–5.86)*

55–64

1.90 (1.75–2.06)*

1.82 (1.70–1.95)*

2.32 (1.99–2.69)*

Models - stratified for time period^c

Diabetes (yes vs. no)

1985–1988

1.70 (1.37–2.11)*

1.24 (1.05–1.46)*

3.22 (2.53–4.10)*

1989–1992

1.56 (1.27–1.92)*

1.27 (0.98–1.64)

2.29 (1.78–2.95)*

1993–1996

1.89 (1.56–2.29)*

1.51 (1.30–1.75)*

2.93 (2.12–4.06)*

1997–2000

2.69 (2.24–3.23)*

2.51 (2.00-3.16)*

3.22 (2.39–4.33)*

2001–2004

2.44 (2.08–2.87)*

2.17 (1.90–2.47)*

3.24 (2.40–4.36)*

2005–2008

2.36 (2.00-2.79)*

2.09 (1.76–2.49)*

3.21 (2.40–4.29)*

2009–2012

2.38 (2.03–2.80)*

2.31 (1.95–2.74)*

2.63 (1.95–3.56)*

2013–2016

1.79 (1.52–2.11)*

1.65 (1.38–1.97)*

2.38 (1.87–3.03)*

Fatal MI

              Relative risk for fatal MI (95% CI)^d

Both sexes

Men

Women

Model 1a (population with diabetes)

Time period^a

1989–1992

1.15 (0.95–1.40)

1.25 (0.93–1.69)

1.06 (0.83–1.35)

1993–1996

1.08 (0.89–1.31)

1.24 (0.93–1.67)

0.91 (0.71–1.17)

1997–2000

1.15 (0.95–1.40)

1.21 (0.90–1.63)

1.11 (0.87–1.42)

2001–2004

0.68 (0.55–0.83)*

0.81 (0.60–1.09)

0.52 (0.39–0.69)*

2005–2008

0.44 (0.35–0.55)*

0.55 (0.40–0.75)*

0.31 (0.23–0.43)*

2009–2012

0.40 (0.32–0.50)*

0.45 (0.33–0.62)*

0.34 (0.25–0.47)*

2013–2016

0.30 (0.24–0.38)*

0.32 (0.23–0.46)*

0.28 (0.20–0.40)*

Male vs. female

1.75 (1.57–1.95)*

Age (years) ^b

65–74

7.83 (6.31–9.72)*

8.78 (6.68–11.53)*

4.60 (3.20–6.62)*

55–64

2.78 (2.21–3.49)*

3.16 (2.37–4.22)*

1.57 (1.06–2.33)*

Model 1b (population without diabetes)

Time period^a

1989–1992

1.00 (0.88–1.13)

0.98 (0.85–1.12)

1.04 (0.86–1.26)

1993–1996

0.80 (0.70–0.90)*

0.74 (0.64–0.85)*

0.93 (0.77–1.14)

1997–2000

0.79 (0.70–0.89)*

0.76 (0.66–0.87)*

0.87 (0.71–1.06)

2001–2004

0.49 (0.43–0.56)*

0.49 (0.43–0.58)*

0.47 (0.37–0.60)*

2005–2008

0.35 (0.31–0.41)*

0.34 (0.29–0.40)*

0.39 (0.31–0.50)*

2009–2012

0.37 (0.32–0.43)*

0.35 (0.29–0.41)*

0.42 (0.34–0.54)*

2013–2016

0.28 (0.24–0.33)*

0.27 (0.23–0.32)*

0.31 (0.24–0.40)*

Male vs. female

2.66 (2.47–2.87)*

Age (years) ^b

65–74

8.60 (7.70–9.59)*

7.30 (6.51–8.18)*

13.28 (10.74–16.41)*

55–64

2.77 (2.46–3.13)*

2.65 (2.35-3.00)*

3.28 (2.59–4.14)*

Models - stratified for time period^c

Diabetes (yes vs. no)

1985–1988

2.28 (1.90–2.73)*

1.68 (1.35–2.08)*

3.43 (2.76–4.27)*

1989–1992

2.61 (2.22–3.06)*

2.15 (1.86–2.49)*

3.48 (2.62–4.62)*

1993–1996

3.03 (2.55–3.59)*

2.84 (2.26–3.57)*

3.35 (2.53–4.43)*

1997–2000

3.23 (2.73–3.83)*

2.72 (2.24–3.31)*

4.15 (3.46–4.98)*

2001–2004

3.04 (2.50–3.70)*

2.79 (2.20–3.53)*

3.60 (2.66–4.86)*

2005–2008

2.76 (2.30–3.32)*

2.76 (2.14–3.55)*

2.73 (2.07–3.60)*

2009–2012

2.53 (2.08–3.08)*

2.38 (1.98–2.86)*

2.93 (1.94–4.41)*

2013–2016

2.51 (1.95–3.23)*

2.26 (1.69–3.02)*

3.20 (2.16–4.74)*