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Fig. 5 | Cardiovascular Diabetology

Fig. 5

From: MCT4-dependent lactate transport: a novel mechanism for cardiac energy metabolism injury and inflammation in type 2 diabetes mellitus

Fig. 5

*Leprdb compared to m Leprdb, #Leprdb + VB124 compared to Leprdb. A Pulsed‐wave Doppler showing: LV mass, E/A ratio and LVEF%. B Representative diagram and quantification of cardiac hypertrophy, fibrosis and oil-drop deposition in mice. C mRNA expression of cardiac Anp and Bnp in mice. D mRNA expression of cardiac Cd36 and Fabp3 in mice. E mRNA expression of cardiac Il-1β and Ccl2 in mice. F Representative diagram and quantification of heart H4K12La positive macrophage (%) in mice. G Representative diagram and quantification of heart HIF-1α positive macrophage (%) in mice. H Representative diagram and quantification of heart iNOS positive macrophage (%) in mice

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